Aconitum and Delphinium alkaloids. "Drug-likeness" descriptors related to toxic mode of action

Environmental Toxicology and Pharmacology

Volumn 25, Issue 3, 2008, Pages 310-320

  Turabekova, Malakhat A ^a,b   Rasulev, Bakhtiyor F ^b   Dzhakhangirov, Farkhad N ^b   Salikhov, Shavkat I ^a  

^a NATIONAL UNIVERSITY OF UZBEKISTAN   (Uzbekistan)

^b S Yu Yunusov Institute of the Chemistry of Plant Substances Uzbekistan Academy of Sciences   (Uzbekistan)

Author keywords

"Drug likeness"; Aconitum alkaloids; Alkaloids; Delphinium alkaloids; QSAR; Toxicity

Indexed keywords

ACONITUM EXTRACT; ALKALOID; ANTIARRHYTHMIC AGENT; CONDELPHINE; DELPHINIUM EXTRACT; DITERPENOID; LAPPACONITINE; METHYLLYCACONITINE HYDROIODIDE; NEUROMUSCULAR BLOCKING AGENT; NICOTINIC RECEPTOR BLOCKING AGENT; PLANT EXTRACT; SODIUM CHANNEL BLOCKING AGENT; UNCLASSIFIED DRUG;

ACONITUM; ANTIARRHYTHMIC ACTIVITY; ARRHYTHMOGENESIS; ARTICLE; DRUG STRUCTURE; LARKSPUR; LD 50; MOLECULAR SIZE; NEUROLOGIC DISEASE; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RELIABILITY; STATISTICAL SIGNIFICANCE; VALIDATION PROCESS;

ACONITUM; DELPHINIUM;

EID: 39649114121     PISSN: 13826689     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etap.2007.10.035     Document Type: Article

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