Human endogenous retrovirus HERV-K113 is capable of producing intact viral particles

Journal of General Virology

Volumn 89, Issue 2, 2008, Pages 567-572

  Boller, Klaus ^a   Schönfeld, Kurt ^a,c   Lischer, Stefanie ^a,d   Fischer, Nicole ^a   Hoffmann, Andreas ^a   Kurth, Reinhard ^b   Tönjes, Ralf R ^a  

^a PAUL EHRLICH INSTITUT   (Germany)

^b ROBERT KOCH INSTITUTE   (Germany)

^c Forschungslabor Hautklinik Heidelberg   (Germany)

^d SWISS FEDERAL LABORATORIES FOR MATERIALS SCIENCE AND TECHNOLOGY   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; CELL LINE; CONTROLLED STUDY; ENDOGENOUS RETROVIRUS; GERM CELL TUMOR; HUMAN GENOME; IN VIVO STUDY; MELANOMA; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROVIRUS; VIRUS DNA CELL DNA INTERACTION; VIRUS GENE; VIRUS MORPHOLOGY; VIRUS PARTICLE; ANIMAL; ARMYWORM; BACULOVIRUS; CELL CULTURE; CLASSIFICATION; GENE VECTOR; GENETICS; GENOME; HUMAN; METABOLISM; PATHOGENICITY; PHYSIOLOGY; ULTRASTRUCTURE; VIRION; VIRUS REPLICATION;

HUMAN ENDOGENOUS RETROVIRUS; HUMAN ENDOGENOUS RETROVIRUSES;

VIRUS DNA;

ANIMALS; BACULOVIRIDAE; CELLS, CULTURED; DNA, VIRAL; ENDOGENOUS RETROVIRUSES; GENETIC VECTORS; GENOME, HUMAN; HUMANS; PROVIRUSES; SPODOPTERA; VIRION; VIRUS REPLICATION;

EID: 39549099581     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.83534-0     Document Type: Article

References (26)

1. Bannert, N. & Kurth, R. (2004). Retroelements and the human genome: new perspectives on an old relation. Proc Natl Acad Sci U S A 101 (Suppl. 2), 14572-14579.
2. Belshaw, R., Pereira, V., Katzourakis, A., Talbot, G., Paces, J., Burt, A. & Tristem, M. (2004). Long-term reinfection of the human genome by endogenous retroviruses. Proc Natl Acad Sci U S A 101, 4894-4899.
3. Bieda, K., Hoffmann, A. & Boller, K. (2001). Phenotypic heterogeneity of human endogenous retrovirus particles produced by teratocarcinoma cell lines. J Gen Virol 82, 591-596.
4. Boller, K., Frank, H., Löwer, J., Löwer, R. & Kurth, R. (1983). Structural organization of unique retrovirus-like particles budding from human teratocarcinoma cell lines. J Gen Virol 64, 2549-2559.
5. Boller, K., König, H., Sauter, M., Mueller-Lantzsch, N., Löwer, R., Löwer, J. & Kurth, R. (1993). Evidence that HERV-K is the endogenous retrovirus sequence that codes for the human teratocarcinoma-derived retrovirus HTDV. Virology 196, 349-353.
6. Boller, K., Janssen, O., Schuldes, H., Tönjes, R. R. & Kurth, R. (1997). Characterization of the antibody response specific for the human endogenous retrovirus HTDV/HERV-K. J Virol 71, 4581-4588.
7. Büscher, K., Hahn, S., Hofmann, M., Trefzer, U., Özel, M., Sterry, W., Löwer, J., Löwer, R., Kurth, R. & Denner, J. (2006). Expression of the human endogenous retrovirus-K transmembrane envelope, Rec and Np9 proteins in melanomas and melanoma cell lines. Melanoma Res 16, 223-234.
8. Dewannieux, M., Blaise, S. & Heidmann, T. (2005). Identification of a functional envelope protein from the HERV-K family of human endogenous retroviruses. J Virol 79, 15573-15577.
9. Dewannieux, M., Harper, F., Richaud, A., Letzelter, C., Ribet, D., Pierron, G. & Heidmann, T. (2006). Identification of an infectious progenitor for the multiple-copy HERV-K human endogenous retroelements. Genome Res 16, 1548-1556.
10. Jeang, K. T., Holmgren-Konig, M. & Khoury, G. (1987). A baculovirus vector can express intron-containing genes. J Virol 61, 1761-1764.
11. Kleiman, A., Senyuta, N., Tryakin, A., Sauter, M., Karseladze, A., Tjulandin, S., Gurtsevitch, V. & Mueller-Lantzsch, N. (2004). HERV-K(HML-2) GAG/ENV antibodies as indicator for therapy effect in patients with germ cell tumors. Int J Cancer 110, 459-461.
12. Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zody, M. C., Baldwin, J., Devon, K., Dewar, K., Doyle, M. & other authors (2001). Initial sequencing and analysis of the human. Nature 409, 860-921.
13. Lee, Y. N. & Bieniasz, P. D. (2007). Reconstitution of an infectious human endogenous retrovirus. PLoS Pathog 3, e10.
14. Löwer, R., Löwer, J., Frank, H., Harzmann, R. & Kurth, R. (1984). Human teratocarcinomas cultured in vitro produce unique retrovirus-like viruses. J Gen Virol 65, 887-898.
15. Löwer, R., Boller, K., Hasenmaier, B., Korbmacher, C., Müller-Lantzsch, N., Löwer, J. & Kurth, R. (1993). Identification of human endogenous retroviruses with complex mRNA expression and particle formation. Proc Natl Acad Sci U S A 90, 4480-4484.
16. Lugert, R., König, H., Kurth, R. & Tönjes, R. R. (1996). Specific suppression of false-positive signals in the product-enhanced reverse transcriptase assay. Biotechniques 20, 210-217.
17. Medstrand, P., Lindeskog, M. & Blomberg, J. (1992). Expression of human endogenous retroviral sequences in peripheral blood mononuclear cells of healthy individuals. J Gen Virol 73, 2463-2466.
18. Moyes, D. L., Martin, A., Sawcer, S., Temperton, N., Worthington, J., Griffiths, D. J. & Venables, P. J. (2005). The distribution of the endogenous retroviruses HERV-K113 and HERV-K115 in health and disease. Genomics 86, 337-341.
19. Mueller-Lantzsch, N., Sauter, M., Welskircher, A., Kramer, K., Best, B., Buck, M. & Grasser, F. (1993). Human endogenous retroviral element K10 (HERV-K10) encodes a full-length gag homologous 73-kDa protein and a functional protease. AIDS Res Hum Retroviruses 9, 343-350.
20. Muster, T., Waltenberger, A., Grassauer, A., Hirschl, S., Caucig, P., Romirer, I., Fodinger, D., Seppele, H., Schanab, O. & other authors (2003). An endogenous retrovirus derived from human melanoma cells. Cancer Res 63, 8735-8741.
21. Sauter, M., Schommer, S., Kremmer, E., Remberger, K., Dolken, G., Lemm, I., Buck, M., Best, B., Neumann-Haefelin, D. & Mueller-Lantzsch, N. (1995). Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas. J Virol 69, 414-421.
22. Schommer, S., Sauter, M., Kräusslich, H. G., Best, B. & Mueller-Lantzsch, N. (1996). Characterization of the human endogenous retrovirus K proteinase. J Gen Virol 77, 375-379.
23. Silver, J., Maudru, T., Fujita, K. & Repaske, R. (1993). An RT-PCR assay for the enzyme activity of reverse transcriptase capable of detecting single virions. Nucleic Acids Res 21, 3593-3594.
24. Tokuyasu, K. T., Dutton, A. H., Geiger, B. & Singer, S. J. (1981). Ultrastructure of chicken cardiac muscle as studied by double immunolabeling in electron microscopy. Proc Natl Acad Sci U S A 78, 7619-7623.
25. Tönjes, R. R., Boller, K., Limbach, C., Lugert, R. & Kurth, R. (1997). Characterization of human endogenous retrovirus type K virus-like particles generated from recombinant baculoviruses. Virology 233, 280-291.
26. Turner, G., Barbulescu, M., Su, M., Jensen-Seaman, M. I., Kidd, K. K. & Lenz, J. (2001). Insertional polymorphisms of full-length endogenous retroviruses in humans. Curr Biol 11, 1531-1535.