Transition-state interactions revealed in purine nucleoside phosphorylase by binding isotope effects

Journal of the American Chemical Society

Volumn 130, Issue 7, 2008, Pages 2166-2167

  Murkin, Andrew S ^a   Tyler, Peter C ^b   Schramm, Vern L ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b CALLAGHAN INNOVATION   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

ISOTOPE; PURINE NUCLEOSIDE PHOSPHORYLASE; FORODESINE; INOSINE; PURINE NUCLEOSIDE; PYRIMIDINONE DERIVATIVE; TRITIUM;

ARTICLE; BINDING COMPETITION; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME MECHANISM; HYDROGEN BOND; MOLECULAR INTERACTION; CHEMISTRY; HUMAN; KINETICS; METABOLISM; THERMODYNAMICS;

BINDING, COMPETITIVE; HUMANS; INOSINE; KINETICS; PURINE NUCLEOSIDES; PURINE-NUCLEOSIDE PHOSPHORYLASE; PYRIMIDINONES; THERMODYNAMICS; TRITIUM;

EID: 39549099106     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja7104398     Document Type: Article

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