메뉴 건너뛰기




Volumn 38, Issue 3, 2008, Pages 190-198

An overview of chronic severe asthma

Author keywords

Chronic severe asthma; Differential diagnosis; Pharmacotherapy; Steroid refractoriness

Indexed keywords

AZATHIOPRINE; BECLOMETASONE DIPROPIONATE; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CORTICOSTEROID; CYCLOSPORIN A; ETANERCEPT; GOLD; IMMUNOGLOBULIN; METHOTREXATE; OMALIZUMAB; PREDNISONE; TROLEANDOMYCIN;

EID: 39449103632     PISSN: 14440903     EISSN: 14455994     Source Type: Journal    
DOI: 10.1111/j.1445-5994.2007.01547.x     Document Type: Review
Times cited : (20)

References (40)
  • 1
    • 0036339313 scopus 로고    scopus 로고
    • Trends in childhood asthma: Prevalence, health care utilization, and mortality
    • Akinbami LJ, Schoendorf KC. Trends in childhood asthma: prevalence, health care utilization, and mortality. Pediatrics 2002 110 : 315 22.
    • (2002) Pediatrics , vol.110 , pp. 315-22
    • Akinbami, L.J.1    Schoendorf, K.C.2
  • 4
    • 22144452574 scopus 로고    scopus 로고
    • Severe asthma in adults
    • Wenzel S. Severe asthma in adults. Am J Respir Crit Care Med 2005 172 : 149 60.
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 149-60
    • Wenzel, S.1
  • 5
    • 33747750597 scopus 로고    scopus 로고
    • The mechanisms, diagnosis, and management of severe asthma in adults
    • Holgate ST, Polosa R. The mechanisms, diagnosis, and management of severe asthma in adults. Lancet 2006 368 : 780 93.
    • (2006) Lancet , vol.368 , pp. 780-93
    • Holgate, S.T.1    Polosa, R.2
  • 6
    • 24744432044 scopus 로고    scopus 로고
    • Difficult asthma in adults: Recognition and approaches to management
    • Harrison BD. Difficult asthma in adults: recognition and approaches to management. Intern Med J 2005 35 : 543 7.
    • (2005) Intern Med J , vol.35 , pp. 543-7
    • Harrison, B.D.1
  • 8
    • 33845987340 scopus 로고    scopus 로고
    • National Heart, Lung, Blood Institute's Severe Asthma Research Program. Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program
    • Moore WC, Bleecker ER, Curran-Everett D, Erzurum SC, Ameredes BT, Bacharier L et al. National Heart, Lung, Blood Institute's Severe Asthma Research Program. Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. J Allergy Clin Immunol 2007 119 : 405 13.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 405-13
    • Moore, W.C.1    Bleecker, E.R.2    Curran-Everett, D.3    Erzurum, S.C.4    Ameredes, B.T.5    Bacharier, L.6
  • 9
  • 10
    • 10744224453 scopus 로고    scopus 로고
    • Allergy Research Group of the National Heart and Lung Institute. Systematic assessment of difficult-to-treat asthma
    • Robinson DS, Campbell DA, Durham SR, Pfeffer J, Barnes PJ, Chung KF et al. Allergy Research Group of the National Heart and Lung Institute. Systematic assessment of difficult-to-treat asthma. Eur Respir J 2003 22 : 478 83.
    • (2003) Eur Respir J , vol.22 , pp. 478-83
    • Robinson, D.S.1    Campbell, D.A.2    Durham, S.R.3    Pfeffer, J.4    Barnes, P.J.5    Chung, K.F.6
  • 11
    • 0038015441 scopus 로고    scopus 로고
    • Predictors of therapy resistant asthma: Outcome of a systematic evaluation protocol
    • Heaney LG, Conway E, Kelly C, Johnston BT, English C, Stevenson M et al. Predictors of therapy resistant asthma: outcome of a systematic evaluation protocol. Thorax 2003 58 : 561 6.
    • (2003) Thorax , vol.58 , pp. 561-6
    • Heaney, L.G.1    Conway, E.2    Kelly, C.3    Johnston, B.T.4    English, C.5    Stevenson, M.6
  • 12
    • 0036858609 scopus 로고    scopus 로고
    • Allergic bronchopulmonary aspergillosis
    • Greenberger PA. Allergic bronchopulmonary aspergillosis. J Allergy Clin Immunol 2002 110 : 685 92.
    • (2002) J Allergy Clin Immunol , vol.110 , pp. 685-92
    • Greenberger, P.A.1
  • 13
    • 0037442282 scopus 로고    scopus 로고
    • Churg-Strauss syndrome
    • Noth I, Strek ME, Leff AR. Churg-Strauss syndrome. Lancet 2003 361 : 587 94.
    • (2003) Lancet , vol.361 , pp. 587-94
    • Noth, I.1    Strek, M.E.2    Leff, A.R.3
  • 15
    • 27644447206 scopus 로고    scopus 로고
    • Aspirin sensitivity and severity of asthma: Evidence for irreversible airway obstruction in patients with severe or difficult-to-treat asthma
    • TENOR Study Group.
    • Mascia K, Haselkorn T, Deniz YM, Miller DP, Bleecker ER, Borish L. TENOR Study Group. Aspirin sensitivity and severity of asthma: evidence for irreversible airway obstruction in patients with severe or difficult-to-treat asthma. J Allergy Clin Immunol 2005 116 : 970 75.
    • (2005) J Allergy Clin Immunol , vol.116 , pp. 970-75
    • Mascia, K.1    Haselkorn, T.2    Deniz, Y.M.3    Miller, D.P.4    Bleecker, E.R.5    Borish, L.6
  • 19
    • 0030801354 scopus 로고    scopus 로고
    • Psychological morbidity and coping skills in patients with brittle and non-brittle asthma: A case-control study
    • Miles JF, Garden GM, Tunnicliffe WS, Cayton RM, Ayres JG. Psychological morbidity and coping skills in patients with brittle and non-brittle asthma: a case-control study. Clin Exp Allergy 1997 27 : 1151 9.
    • (1997) Clin Exp Allergy , vol.27 , pp. 1151-9
    • Miles, J.F.1    Garden, G.M.2    Tunnicliffe, W.S.3    Cayton, R.M.4    Ayres, J.G.5
  • 20
    • 39449093271 scopus 로고    scopus 로고
    • Global Initiative for Asthma. Bethesda: NIH Publication Number 02-3659. Cited 2006 Nov 9. Available from URL:
    • Global Initiative for Asthma. Global strategy for asthma management and prevention. A six part management program. Bethesda : NIH Publication Number 02-3659 Cited 2006 Nov 9 Available from URL : http://www.ginasthma.org
    • Global Strategy for Asthma Management and Prevention. a Six Part Management Program
  • 21
    • 33644874322 scopus 로고    scopus 로고
    • Long-acting beta2-agonists as an inhaled corticosteroid sparing agent for chronic asthma in adults and children
    • CD 005076.
    • Gibson P, Powell H, Ducharme FJ. Long-acting beta2-agonists as an inhaled corticosteroid sparing agent for chronic asthma in adults and children. Cochrane Database Syst Rev 2005 4 : CD 005076.
    • (2005) Cochrane Database Syst Rev , vol.4
    • Gibson, P.1    Powell, H.2    Ducharme, F.J.3
  • 22
    • 0030791292 scopus 로고    scopus 로고
    • Low-dose methotrexate spares steroid usage in steroid-dependent asthmatic patients: A meta-analysis
    • Marin MG. Low-dose methotrexate spares steroid usage in steroid-dependent asthmatic patients: a meta-analysis. Chest 1997 112 : 29 33.
    • (1997) Chest , vol.112 , pp. 29-33
    • Marin, M.G.1
  • 23
    • 0031720221 scopus 로고    scopus 로고
    • Management of steroid-dependent asthma with methotrexate: A meta-analysis of randomized clinical trials
    • Aaron SD, Dales RE, Pham B. Management of steroid-dependent asthma with methotrexate: a meta-analysis of randomized clinical trials. Respir Med 1998 92 : 1059 65.
    • (1998) Respir Med , vol.92 , pp. 1059-65
    • Aaron, S.D.1    Dales, R.E.2    Pham, B.3
  • 24
    • 85016765389 scopus 로고    scopus 로고
    • Methotrexate as a steroid-sparing agent for asthma in adults
    • CD 000391.
    • Davies H, Olson L, Gibson P. Methotrexate as a steroid-sparing agent for asthma in adults. Cochrane Database Syst Rev 2000 2 CD 000391.
    • (2000) Cochrane Database Syst Rev , Issue.2
    • Davies, H.1    Olson, L.2    Gibson, P.3
  • 25
    • 0025268469 scopus 로고
    • Long-term methotrexate treatment in corticosteroid-dependent asthma
    • Mullarkey MF, Lammert JK, Blumenstein BA. Long-term methotrexate treatment in corticosteroid-dependent asthma. Ann Intern Med 1990 112 : 577 81.
    • (1990) Ann Intern Med , vol.112 , pp. 577-81
    • Mullarkey, M.F.1    Lammert, J.K.2    Blumenstein, B.A.3
  • 27
    • 32644435868 scopus 로고    scopus 로고
    • Benefits of low weekly doses of methotrexate in steroid-dependent asthmatic patients. a double-blind, randomized, placebo-controlled study
    • Comet R, Domingo C, Larrosa M, Moron A, Rue M, Amengual MJ et al. Benefits of low weekly doses of methotrexate in steroid-dependent asthmatic patients. A double-blind, randomized, placebo-controlled study. Respir Med 2006 100 : 411 19.
    • (2006) Respir Med , vol.100 , pp. 411-19
    • Comet, R.1    Domingo, C.2    Larrosa, M.3    Moron, A.4    Rue, M.5    Amengual, M.J.6
  • 28
    • 10144255093 scopus 로고    scopus 로고
    • A placebo controlled multicenter study of auranofin in the treatment of patients with corticosteroid-dependent asthma. Auranofin Multicenter Drug Trial
    • Bernstein IL, Bernstein DI, Dubb JW, Faiferman I, Wallin B. A placebo controlled multicenter study of auranofin in the treatment of patients with corticosteroid-dependent asthma. Auranofin Multicenter Drug Trial. J Allergy Clin Immunol 1996 98 : 317 24.
    • (1996) J Allergy Clin Immunol , vol.98 , pp. 317-24
    • Bernstein, I.L.1    Bernstein, D.I.2    Dubb, J.W.3    Faiferman, I.4    Wallin, B.5
  • 29
    • 0026529218 scopus 로고
    • Trial of cyclosporin in corticosteroid-dependent chronic severe asthma
    • Alexander AG, Barnes NC, Kay AB. Trial of cyclosporin in corticosteroid-dependent chronic severe asthma. Lancet 1992 339 : 324 8.
    • (1992) Lancet , vol.339 , pp. 324-8
    • Alexander, A.G.1    Barnes, N.C.2    Kay, A.B.3
  • 30
    • 0030071686 scopus 로고    scopus 로고
    • Double-blind, placebocontrolled study of cyclosporin a as a corticosteroid-sparing agent in corticosteroid-dependent asthma
    • Lock SH, Kay AB, Barnes NC. Double-blind, placebocontrolled study of cyclosporin A as a corticosteroid-sparing agent in corticosteroid-dependent asthma. Am J Respir Crit Care Med 1996 153 : 509 14.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 509-14
    • Lock, S.H.1    Kay, A.B.2    Barnes, N.C.3
  • 32
    • 0033057149 scopus 로고    scopus 로고
    • Effect of intravenous immunoglobulin on steroid consumption in patients with severe asthma: A double-blind, placebo-controlled, randomized trial
    • Salmun LM, Barlan I, Wolf HM, Eibl M, Twarog FJ, Geha RS et al. Effect of intravenous immunoglobulin on steroid consumption in patients with severe asthma: a double-blind, placebo-controlled, randomized trial. J Allergy Clin Immunol 1999 103 : 810 15.
    • (1999) J Allergy Clin Immunol , vol.103 , pp. 810-15
    • Salmun, L.M.1    Barlan, I.2    Wolf, H.M.3    Eibl, M.4    Twarog, F.J.5    Geha, R.S.6
  • 33
    • 0032938814 scopus 로고    scopus 로고
    • A multi-center, randomized, double-blind, placebo-controlled trial of high-dose intravenous immunoglobulin for oral corticosteroid-dependent asthma
    • Kishiyama JL, Valacer D, Cunningham-Rundles C, Sperber K, Richmond GW, Abramson S et al. A multi-center, randomized, double-blind, placebo-controlled trial of high-dose intravenous immunoglobulin for oral corticosteroid-dependent asthma. Clin Immunol 1999 91 : 126 33.
    • (1999) Clin Immunol , vol.91 , pp. 126-33
    • Kishiyama, J.L.1    Valacer, D.2    Cunningham-Rundles, C.3    Sperber, K.4    Richmond, G.W.5    Abramson, S.6
  • 34
    • 0027518873 scopus 로고
    • A double-blind study of troleandomycin and methylprednisolone in asthmatic subjects who require daily corticosteroids
    • Nelson HS, Hamilos DL, Corsello PR, Levesque NV, Buchmeier AD, Bucher BL. A double-blind study of troleandomycin and methylprednisolone in asthmatic subjects who require daily corticosteroids. Am Rev Respir Dis 1993 147 : 398 404.
    • (1993) Am Rev Respir Dis , vol.147 , pp. 398-404
    • Nelson, H.S.1    Hamilos, D.L.2    Corsello, P.R.3    Levesque, N.V.4    Buchmeier, A.D.5    Bucher, B.L.6
  • 36
    • 28244479315 scopus 로고    scopus 로고
    • Tumour necrosis factor (TNFalfa) as a novel therapeutic target in symptomatic corticosteroid dependent asthma
    • Howarth PH, Babu KS, Arshad HS, Lau L, Buckley M, McConnell W et al. Tumour necrosis factor (TNFalfa) as a novel therapeutic target in symptomatic corticosteroid dependent asthma. Thorax 2005 60 : 1012 18.
    • (2005) Thorax , vol.60 , pp. 1012-18
    • Howarth, P.H.1    Babu, K.S.2    Arshad, H.S.3    Lau, L.4    Buckley, M.5    McConnell, W.6
  • 39
    • 33244464083 scopus 로고    scopus 로고
    • Impact of omalizumab on quality-of-life outcomes in patients with moderate-to-severe allergic asthma
    • Niebauer K, Dewilde S, Fox-Rushby J, Revicki DA. Impact of omalizumab on quality-of-life outcomes in patients with moderate-to-severe allergic asthma. Ann Allergy Asthma Immunol 2006 96 : 316 26.
    • (2006) Ann Allergy Asthma Immunol , vol.96 , pp. 316-26
    • Niebauer, K.1    Dewilde, S.2    Fox-Rushby, J.3    Revicki, D.A.4
  • 40
    • 20044362008 scopus 로고    scopus 로고
    • Benefits of omalizumab as add-on therapy in patients with severe persistent asthma who are inadequately controlled despite best available therapy (GINA 2002 step 4 treatment): INNOVATE
    • Humbert M, Beasley R, Ayres J, Slavin R, Hebert J, Bousquet J et al. Benefits of omalizumab as add-on therapy in patients with severe persistent asthma who are inadequately controlled despite best available therapy (GINA 2002 step 4 treatment): INNOVATE. Allergy 2005 60 : 309 16.
    • (2005) Allergy , vol.60 , pp. 309-16
    • Humbert, M.1    Beasley, R.2    Ayres, J.3    Slavin, R.4    Hebert, J.5    Bousquet, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.