Interferon-γ (IFN-γ): A possible prognostic marker for clearance of high-risk human papillomavirus (HPV)

Gynecologic Oncology

Volumn 108, Issue 3, 2008, Pages 543-548

  Song, Seung Hun ^a   Lee, Jae Kwan ^b   Lee, Nak Woo ^b   Saw, Ho Suk ^b   Kang, Jae Sung ^b   Lee, Kyu Wan ^b  

^a Sun General Hospital   (South Korea)

^b Korea University College of Medicine   (South Korea)

Author keywords

Human papillomavirus (HPV); Interferon (IFN ); Interleukin 10 (IL 10); Interleukin 6 (IL 6); Tumor necrosis factor (TNF )

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 6; ORAL CONTRACEPTIVE AGENT; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MENSTRUAL CYCLE; PRIORITY JOURNAL; PROGNOSIS; REAL TIME POLYMERASE CHAIN REACTION; SMOKING; UTERINE CERVIX BIOPSY; UTERINE CERVIX DYSPLASIA; WART VIRUS;

EID: 39249085187     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2007.11.006     Document Type: Article

References (41)

1. Ambros R.A., and Kurman R.J. Current concepts in the relationship of human papillomavirus infection to the pathogenesis and classification of precancerous squamous lesions of the uterine cervix. Semin Diagn Pathol 7 3 (1990) 158-172
2. Josefsson A.M., Magnusson P.K., Ylitalo N., Sorensen P., Qwarforth-Tubbin P., Andersen P.K., et al. Viral load of human papilloma virus 16 as a determinant for development of cervical carcinoma in situ: a nested case-control study. Lancet 355 9222 (2000) 2189-2193
3. Kjaer S.K., van den Brule A.J., Paull G., Svare E.I., Sherman M.E., Thomsen B.L., et al. Type specific persistence of high risk human papillomavirus (HPV) as indicator of high grade cervical squamous intraepithelial lesions in young women: population based prospective follow up study. BMJ 325 7364 (2002) 572-578
4. Nobbenhuis M.A., Walboomers J.M., Helmerhorst T.J., Rozendaal L., Remmink A.J., Risse E.K., et al. Relation of human papillomavirus status to cervical lesions and consequences for cervical-cancer screening: a prospective study. Lancet 354 9172 (1999) 20-25
5. Sellors J.W., Mahony J.B., Kaczorowski J., Lytwyn A., Bangura H., Chong S., et al. Prevalence and predictors of human papillomavirus infection in women in Ontario, Canada. Survey of HPV in Ontario Women (SHOW) Group. CMAJ 163 5 (2000) 503-508
6. zur Hausen H. Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis. J Natl Cancer Inst 92 9 (2000) 690-698
7. Kyo S., Inoue M., Hayasaka N., Inoue T., Yutsudo M., Tanizawa O., et al. Regulation of early gene expression of human papillomavirus type 16 by inflammatory cytokines. Virology 200 1 (1994) 130-139
8. Clerici M., and Shearer G.M. The Th1-Th2 hypothesis of HIV infection: new insights. Immunol Today 15 12 (1994) 575-581
9. Spellberg B., and Edwards Jr. J.E. Type 1/Type 2 immunity in infectious diseases. Clin Infect Dis 32 1 (2001) 76-102
10. Kadish A.S., Ho G.Y., Burk R.D., Wang Y., Romney S.L., Ledwidge R., et al. Lymphoproliferative responses to human papillomavirus (HPV) type 16 proteins E6 and E7: outcome of HPV infection and associated neoplasia. J Natl Cancer Inst 89 17 (1997) 1285-1293
11. Sharma A, Rajappa M, Saxena A, Sharma M. Cytokine profile in Indian women with cervical intraepithelial neoplasia and cancer cervix. Int J Gynecol Cancer 17(4):879-85.
12. Aggarwal B.B. Signalling pathways of the TNF superfamily: a double-edged sword. Nat Rev Immunol 3 9 (2003) 745-756
13. Arany I., Grattendick K.G., and Tyring S.K. Interleukin-10 induces transcription of the early promoter of human papillomavirus type 16 (HPV 16) through the 5-segment of the upstream regulatory region (URR). Antiviral Res 55 2 (2002) 331-339
14. Farzaneh F., Roberts S., Mandal D., Ollier B., Winters U., Kitchener H.C., et al. The IL-10-1082G polymorphism is associated with clearance of HPV infection. BJOG 113 8 (2006) 961-964
15. Scott M., Stites D.P., and Moscicki A.B. Th1 cytokine patterns in cervical human papillomavirus infection. Clin Diagn Lab Immunol 6 5 (1999) 751-755
16. Scott M., Nakagawa M., and Moscicki A.B. Cell-mediated immune response to human papillomavirus infection. Clin Diagn Lab Immunol 8 2 (2001) 209-220
17. Tjiong M.Y., van der Vange N., ten Kate F.J., Tjong-A-Hung S.P., ter Schegget J., Burger M.P., et al. Increased IL-6 and IL-8 levels in cervicovaginal secretions of patients with cervical cancer. Gynecol Oncol 73 2 (1999) 285-291
18. Wei L.H., Kuo M.L., Chen C.A., Cheng W.F., Cheng S.P., Hsieh F.J., et al. Interleukin-6 in cervical cancer: the relationship with vascular endothelial growth factor. Gynecol Oncol 82 1 (2001) 49-56
19. Wu T.C., and Kurman R.J. Analysis of cytokine profiles in patients with human papillomavirus-associated neoplasms. J Natl Cancer Inst 89 3 (1997) 185-187
20. Castellsague X., and Munoz N. Chapter 3: cofactors in human papillomavirus carcinogenesis-role of parity, oral contraceptives, and tobacco smoking. J Natl Cancer Inst Monogr 31 (2003) 20-28
21. Garcia-Pineres A.J., Hildesheim A., Herrero R., Trivett M., Williams M., Atmetlla I., et al. Persistent human papillomavirus infection is associated with a generalized decrease in immune responsiveness in older women. Cancer Res 66 22 (2006) 11070-11076
22. Gravitt P.E., Hildesheim A., Herrero R., Schiffman M., Sherman M.E., Bratti M.C., et al. Correlates of IL-10 and IL-12 concentrations in cervical secretions. J Clin Immunol 23 3 (2003) 175-183
23. Scott M.E., Ma Y., Farhat S., Shiboski S., and Moscicki A.B. Covariates of cervical cytokine mRNA expression by real-time PCR in adolescents and young women: effects of Chlamydia trachomatis infection, hormonal contraception, and smoking. J Clin Immunol 26 3 (2006) 222-232
24. Wang-Johanning F., Lu D.W., Wang Y., Johnson M.R., and Johanning G.L. Quantitation of human papillomavirus 16 E6 and E7 DNA and RNA in residual material from ThinPrep Papanicolaou tests using real-time polymerase chain reaction analysis. Cancer 94 8 (2002) 2199-2210
25. Govan V.A., Carrara H.R., Sachs J.A., Hoffman M., Stanczuk G.A., and Williamson A.L. Ethnic differences in allelic distribution of IFN-γ in South African women but no link with cervical cancer. J Carcinog 2 1 (2003) 3
26. Welters M.J., de Jong A., van den Eeden S.J., van der Hulst J.M., Kwappenberg K.M., Hassane S., et al. Frequent display of human papillomavirus type 16 E6-specific memory t-Helper cells in the healthy population as witness of previous viral encounter. Cancer Res 63 3 (2003) 636-641
27. Lai H.C., Chang C.C., Lin Y.W., Chen S.F., Yu M.H., Nieh S., et al. Genetic polymorphism of the interferon-gamma gene in cervical carcinogenesis. Int J Cancer 113 5 (2005) 712-718
28. Song S.H., Lee J.K., Seok O.S., and Saw H.S. The relationship between cytokines and HPV-16, HPV-16 E6, E7, and high-risk HPV viral load in the uterine cervix. Gynecol Oncol 104 3 (2007) 732-738
29. Rafiq K., Charitidou L., Bullens D.M., Kasran A., Lorre K., Ceuppens J., et al. Regulation of the IL-10 production by human T cells. Scand J Immunol 53 2 (2001) 139-147
30. Garzetti G.G., Ciavattini A., Goteri G., De Nictolis M., Menso S., Muzzioli M., et al. HPV DNA positivity and natural killer cell activity in the clinical outcome of mild cervical dysplasia: integration between virus and immune system. Gynecol Obstet Invest 39 2 (1995) 130-135
31. Malejczyk J., Malejczyk M., Urbanski A., Kock A., Jablonska S., Orth G., et al. Constitutive release of IL6 by human papillomavirus type 16 (HPV16)-harboring keratinocytes: a mechanism augmenting the NK-cell-mediated lysis of HPV-bearing neoplastic cells. Cell Immunol 136 1 (1991) 155-164
32. Boccardo E., Noya F., Broker T.R., Chow L.T., and Villa L.L. HPV-18 confers resistance to TNF-alpha in organotypic cultures of human keratinocytes. Virology 328 2 (2004) 233-243
33. Majewski S., Hunzelmann N., Nischt R., Eckes B., Rudnicka L., Orth G., et al. TGF beta-1 and TNF alpha expression in the epidermis of patients with epidermodysplasia verruciformis. J Invest Dermatol 97 50 (1991) 862-867
34. Gaiotti D., Chung J., Iglesias M., Nees M., Baker P.D., Evans C.H., et al. Tumor necrosis factor-alpha promotes human papillomavirus (HPV) E6/E7 RNA expression and cyclin-dependent kinase activity in HPV-immortalized keratinocytes by a ras-dependent pathway. Mol Carcinog 27 2 (2000) 97-109
35. Manchester K.M., Heston W.D., and Donner D.B. Tumour necrosis factor-induced cytotoxicity is accompanied by intracellular mitogenic signals in ME-180 human cervical carcinoma cells. Biochem J 290 Pt 1 (1993) 185-190
36. Ahmed M.I., Salahy E.E., Fayed T.T., El-Hefnawy N.G., and Khalifa A. Human papillomavirus infection among Egyptian females with cervical carcinoma: relationship to spontaneous apoptosis and TNF-alpha. Clin Biochem 34 6 (2001) 491-498
37. Castle P.E., Hildesheim A., Bowman F.P., Strickler H.D., Walker J.L., Pustilnik T., et al. Cervical concentrations of interleukin-10 and interleukin-12 do not correlate with plasma levels. J Clin Immunol 22 1 (2002) 23-27
38. Azar K.K., Tani M., Yasuda H., Sakai A., Inoue M., and Sasagawa T. Increased secretion patterns of interleukin-10 and tumor necrosis factor-alpha in cervical squamous intraepithelial lesions. Hum Pathol 35 11 (2004) 1376-1384
39. Crowley-Nowick P.A., Ellenberg J.H., Vermund S.H., Douglas S.D., Holland C.A., and Moscicki A.B. Cytokine profile in genital tract secretions from female adolescents: impact of human immunodeficiency virus, human papillomavirus, and other sexually transmitted pathogens. J Infect Dis 181 3 (2000) 939-945
40. Hildesheim A., McShane L.M., Schiffman M., Bratti M.C., Rodriguez A.C., Herrero R., et al. Cytokine and immunoglobulin concentrations in cervical secretions: reproducibility of the Weck-cel collection instrument and correlates of immune measures. J Immunol Methods 225 1-2 (1999) 131-143
41. Woodman C.B., Collins S.I., and Young L.S. The natural history of cervical HPV infection: unresolved issues. Nat Rev Cancer 7 1 (2007) 11-22