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A review of novel biomarkers of AKI is presented
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Kidney NGAL is a novel early marker of acute injury following transplantation
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Mishra J, Ma Q, Kelly C, et al. Kidney NGAL is a novel early marker of acute injury following transplantation. Pediatr Nephrol 2006; 21:856-863.
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Mishra, J.1
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16
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Urine NGAL and IL-18 are predictive biomarkers for delayed graft function following kidney transplantation
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In a multicenter study, urine NGAL and IL-18 levels were identified as promising biomarkers of delayed graft function after kidney transplantation
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Parikh CR, Jani A, Mishra J, et al. Urine NGAL and IL-18 are predictive biomarkers for delayed graft function following kidney transplantation. Am J Transplant 2006; 6:1639-1645. In a multicenter study, urine NGAL and IL-18 levels were identified as promising biomarkers of delayed graft function after kidney transplantation.
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Parikh, C.R.1
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Urinary NGAL in D+HUS: A novel marker of renal injury
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NGAL is an early predictive biomarker of contrast-induced nephropathy in children
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Hirsch R, Dent C, Pfriem H, et al. NGAL is an early predictive biomarker of contrast-induced nephropathy in children. Pediatr Nephrol 2007; 22:2089-2095.
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Urine neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in critically ill children: A prospective cohort study
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Zappitelli M, Washburn KK, Arikan AA, et al. Urine neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in critically ill children: a prospective cohort study. Crit Care 2007; 11:R84. This prospective study identified NGAL as a promising biomarker that predicted development and severity of AKI in a heterogeneous cohort of critically ill patients with unknown timing of kidney injury.
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Crit Care
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Zappitelli, M.1
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Parikh CR, Mishra J, Thiessen-Philbrook H, et al. Urinary IL-18 is an early predictive biomarker of acute kidney injury after cardiac surgery. Kidney Int 2006; 70:199-203. NGAL and IL-18 were identified as early sequential biomarkers for AKI and adverse clinical outcomes.
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Parikh CR, Mishra J, Thiessen-Philbrook H, et al. Urinary IL-18 is an early predictive biomarker of acute kidney injury after cardiac surgery. Kidney Int 2006; 70:199-203. NGAL and IL-18 were identified as early sequential biomarkers for AKI and adverse clinical outcomes.
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24
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27
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Han WK, Waikar SS, Johnson A, et al. Urinary biomarkers in the early diagnosis of acute kidney injury. Kidney Int 2007 [Epub ahead of print].
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Kidney Int
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Han, W.K.1
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30
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33947262956
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Urinary N-acetyl-beta-(D)-glucosaminidase activity and kidney injury molecule-1 level are associated with adverse outcomes in acute renal failure
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This study showed that elevated urinary KIM-1 levels are associated with adverse outcomes in hospitalized patients who develop AKI
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Liangos O, Perianayagam MC, Vaidya VS, et al. Urinary N-acetyl-beta-(D)-glucosaminidase activity and kidney injury molecule-1 level are associated with adverse outcomes in acute renal failure. J Am Soc Nephrol 2007; 18:904-912. This study showed that elevated urinary KIM-1 levels are associated with adverse outcomes in hospitalized patients who develop AKI.
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J Am Soc Nephrol
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Liangos, O.1
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31
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Projecting the number of patients with end-stage renal disease in the United States to the year 2015
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Testing for chronic kidney disease: A position statement from the National Kidney Foundation
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Vassalotti JA, Stevens LA, Levey AS. Testing for chronic kidney disease: a position statement from the National Kidney Foundation. Am J Kidney Dis 2007; 50:169-180.
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Renal risk and renoprotection among ethnic groups with type 2 diabetic nephropathy: A post hoc analysis of RENAAL
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de Zeeuw D, Ramjit D, Zhang Z, et al. Renal risk and renoprotection among ethnic groups with type 2 diabetic nephropathy: a post hoc analysis of RENAAL. Kidney Int 2006; 69:1675-1682.
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33846421334
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Serum neutrophil gelatinase-associated lipocalin as a marker of renal function in children with chronic kidney disease
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This study showed that serum NGAL outperforms cystatin C as a biomarker in CKD
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Mitsnefes MM, Kathman TS, Mishra J, et al. Serum neutrophil gelatinase-associated lipocalin as a marker of renal function in children with chronic kidney disease. Pediatr Nephrol 2007; 22:101-108. This study showed that serum NGAL outperforms cystatin C as a biomarker in CKD.
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Pediatr Nephrol
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Mitsnefes, M.M.1
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Urinary neutrophil gelatinase-associated lipocalin (NGAL) is associated with severity of renal disease in proteinuric patients
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Can cystatin C replace creatinine to estimate glomerular filtration rate? A literature review
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Zahran A, El-Husseini A, Shoker A. Can cystatin C replace creatinine to estimate glomerular filtration rate? A literature review. Am J Nephrol 2007; 27:197-205.
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Ravani P, Tripepi G, Malberti F, et al. Asymmetrical dimethylarginine predicts progression to dialysis and death in patients with chronic kidney disease: a competing risks modeling approach. J Am Soc Nephrol 2005; 16:2449-2455.
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40
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33745898830
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Urinary liver-type fatty acid binding protein as a useful biomarker in chronic kidney disease
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This study identified urinary L-FABP as a biomarker in CKD
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Kamijo A, Sugaya T, Hikawa A, et al. Urinary liver-type fatty acid binding protein as a useful biomarker in chronic kidney disease. Mol Cell Biochem 2006; 284 (1-2):175-182. This study identified urinary L-FABP as a biomarker in CKD.
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Kamijo, A.1
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41
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Asymmetric dimethylarginine and progression of chronic kidney disease: The mild to moderate kidney disease study
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Fliser D, Kronenberg F, Kielstein JT, et al. Asymmetric dimethylarginine and progression of chronic kidney disease: the mild to moderate kidney disease study. J Am Soc Nephrol 2005; 16:2456-2461.
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Matsuguma K, Ueda S, Yamagishi S, et al. Molecular mechanism for elevation of asymmetric dimethylarginine and its role for hypertension in chronic kidney disease. J Am Soc Nephrol 2006; 17:2176-2183.
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Dent CL, Ma Q, Dastrala S, et al. Plasma NGAL predicts acute kidney injury, morbidity and mortality after pediatric cardiac surgery: a prospective uncontrolled cohort study. Crit Care 2007; 11:R127.
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in press
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Bennett M, Dent CL, Ma Q, et al. Urine NGAL predicts severity of acute kidney injury after cardiac surgery: a prospective study. Clin J Am Soc Nephrol (in press).
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