PPARα and PPARβ Are differentially affected by ethanol and the ethanol metabolite acetaldehyde in the MCF-7 breast cancer cell line

Toxicological Sciences

Volumn 102, Issue 1, 2008, Pages 120-128

  Venkata, Nagaraj Gopisetty ^a   Aung, Cho S ^a   Cabot, Peter J ^a   Monteith, Gregory R ^a   Roberts Thomson, Sarah J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Acetaldehyde; Breast; Cell lines; Ethanol; MCF 7; PPAR; Proliferation

Indexed keywords

2 [4 [2 [3 CYCLOHEXYL 1 (4 CYCLOHEXYLBUTYL)UREIDO]ETHYL]PHENYLTHIO] 2 METHYLPROPIONIC ACID; 4 METHYLPYRAZOLE; [4 [2 (3 FLUORO 4 TRIFLUOROMETHYLPHENYL) 4 METHYL 5 THIAZOLYLMETHYLTHIO] 2 METHYLPHENOXY]ACETIC ACID; ACETALDEHYDE; ALCOHOL; CYANAMIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; ENZYME INHIBITOR; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PYRAZOLE DERIVATIVE; THIAZOLE DERIVATIVE;

ALCOHOL CONSUMPTION; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER RISK; CELL STRAIN MCF 7; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; HUMAN CELL; PROTEIN FUNCTION; RECEPTOR UPREGULATION; TRANSACTIVATION; TRANSCRIPTION REGULATION; BREAST TUMOR; CHEMICALLY INDUCED DISORDER; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; METABOLISM; TUMOR CELL LINE;

ACETALDEHYDE; ALCOHOL DEHYDROGENASE; ALDEHYDE OXIDOREDUCTASES; BREAST NEOPLASMS; CELL LINE, TUMOR; CYANAMIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; ETHANOL; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; PPAR ALPHA; PPAR-BETA; PYRAZOLES; RNA, MESSENGER; THIAZOLES; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 39149132477     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm281     Document Type: Article

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