PMS777, a bis-interacting ligand for PAF receptor antagonism and AChE inhibition, attenuates PAF-induced neurocytotoxicity in SH-SY5Y cells

Cellular and Molecular Neurobiology

Volumn 28, Issue 1, 2008, Pages 125-136

  Li, Juan ^a   Shao, Biyun ^a   Zhu, Liang ^a   Cui, Yongyao ^a   Dong, Changzhi ^b   Miezan Ezoulin, Jean Marc ^a   Gao, Xiaoling ^a   Ren, Qiushi ^c   Heymans, Françoise ^b   Chen, Hongzhuan ^a,c  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Laboratoire de Pharmacochimie   (France)

^c SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Bax; Bcl 2; Caspase 3; Cox 2; Intracellular calcium; PAF; PMS777

Indexed keywords

ACETYLCHOLINESTERASE; CASPASE 3; CYCLOOXYGENASE 2; MESSENGER RNA; PMS 777; PROTEIN BAX; PROTEIN BCL 2; TETRAHYDROFURAN DERIVATIVE; THROMBOCYTE ACTIVATING FACTOR RECEPTOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; ENZYME ACTIVATION; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; NERVE CELL LESION; NEUROBLASTOMA CELL; NEUROTOXICITY; PRIORITY JOURNAL;

ACETYLCHOLINESTERASE; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CALCIUM; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; CHOLINESTERASE INHIBITORS; CYCLOOXYGENASE 2; FURANS; GENE EXPRESSION REGULATION; HUMANS; INTRACELLULAR SPACE; LIGANDS; NEURONS; NEUROTOXINS; PLATELET ACTIVATING FACTOR; PLATELET MEMBRANE GLYCOPROTEINS; PROTEASE INHIBITORS; RECEPTORS, G-PROTEIN-COUPLED; RNA, MESSENGER;

HUMAN IMMUNODEFICIENCY VIRUS 1; MUS;

EID: 39149119919     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10571-007-9190-9     Document Type: Article

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