Platelet-activating factor induces cyclooxygenase-2 gene expression in corneal epithelium: Requirement of calcium in the signal transduction pathway

Investigative Ophthalmology and Visual Science

Volumn 38, Issue 12, 1997, Pages 2492-2501

  Bazan, Haydee E P ^a,b   Tao, Ying ^a   DeCoster, Mark A ^a   Bazan, Nicolas G ^a  

^a LSU EYE CENTER   (United States)

^b LOUISIANA STATE UNIV MEDICAL CENTER   (United States)

Author keywords

Calcium dependence; Corneal epithelium; Cyclooxygenase 2; Platelet activating factor; Prostaglandins

Indexed keywords

CALCIMYCIN; CALCIUM IONOPHORE; DACTINOMYCIN; MONOCLONAL ANTIBODY; THROMBOCYTE ACTIVATING FACTOR;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM METABOLISM; EPITHELIUM CELL; EYE INFLAMMATION; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; MICROSCOPY; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; RABBIT; SIGNAL TRANSDUCTION;

ANILINE COMPOUNDS; ANIMALS; AZEPINES; BLOTTING, NORTHERN; BLOTTING, WESTERN; CALCIMYCIN; CALCIUM; CYCLOOXYGENASE 2; ENZYME INDUCTION; EPITHELIUM, CORNEAL; FLUORESCENT DYES; GENE EXPRESSION; IONOPHORES; ISOENZYMES; MICROSCOPY, CONFOCAL; ORGAN CULTURE TECHNIQUES; PEROXIDASES; PLATELET ACTIVATING FACTOR; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RABBITS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRIAZOLES; XANTHENES;

EID: 0030815781     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Xie W, Chipman JG, Robertson DL, Erikson RL, Simmons DL. Expression of a mitogen responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc Natl Acad Sci USA. 1991;88:2692-2696.
2. O'Banion MK, Sadowski HB, Winn V, Young DA. A serum and glucocorticoid-regulated 4-kilobase mRNA encodes a cyclooxygenase-related protein. J Biol Chem. 1991;266:23261-23267.
3. Kujuba DA, Fietcher BS, Varnum BC, Lim RW, Herschman HR. TIS10, a phorbol ester tumor promoter inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue. J Biol Chem. 1991;266:12866-12872.
4. Sirois J, Richards JS. Purification and characterization of a novel, distinct isoform of prostaglandin endoperoxidase synthase induced by human chronic gonadotropin in granulosa cells of rat preovulatory follicles. J Biol Chem. 1992;267:6382-6388.
5. Hemler M, Lands WEM, Smith WL. Purification of the cyclo-oxygenase that forms prostaglandins. Demonstration of the two forms of iron in the holoenzyme. J Biol Chem. 1976;251:5575-5579.
6. DeWitt DL, Smith WL. Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence. Proc Natl Acad Sci USA. 1988;85:1212-1416.
7. Jones DA, Carton DP, McIntyre TM, Zimmerman GA, Prescott SM. Molecular clonings of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines. J Biol Chem. 1993;268:9049-9054.
8. DeWitt DL, Meade EA. Serum and glucocorticoid regulation of gene transcription and expression of the prostaglandin H synthase-1 and prostaglandin H synthase-2 isoenzymes. Arch Biochem Biophys. 1993; 306:94-102.
9. Kujuba DA, Herschman HR. Dexamethasone inhibits mitogen induction of the TIS10 prostaglandin synthase/cyclooxygenase gene. J Biol Chem. 1992; 267:7991-7994.
10. Bazan HEP, Birkle DL, Beuerman R, Bazan NG. Cryogenic lesion alters the metabolism of arachidonic acid in rabbit cornea layers. Invest Ophthalmol Vis Sci. 1985;26:474-480.
11. Bazan HEP. Corneal injury alters eicosanoid formation in the rabbit anterior segment in vivo. Invest Ophthalmol Vis Sci. 1987;28:314-319.
12. Bazan HEP. The synthesis and effects of eicosanoids in avascular ocular tissues. In: L Bito, ed. Ocular Effects of Prostaglandins and Other Eicosanoids. New York: Alan R. Liss; 1989:73-84.
13. 2: Effects of EGF and indomethacin. Invest Ophthalmol Vis Sci. 1986;27:1437-1442.
14. 2 on corneal inflammation in the rat. Exp Eye Res. 1993;57:499-501.
15. Ben Ezra D. Neovasculogenic ability of prostaglandins, growth factors and synthetic chemoattractants. Am J Ophthalmol. 1978;86:455-458.
16. Verbey NLJ, van Haeringen NJ, de Jong PTVM. Modulation of immunogenic keratitis in rabbits by topical administration of inhibitors of lipoxygenase and cyclooxygenase. Curr Eye Res. 1988;7:361-368.
17. Szerenyi K, Sorken K, Gorbus JJ, Lee M, McDonnell PJ. Decrease in normal human corneal sensitivity with topical diclofenac sodium. Am J Ophthalmol. 1994; 118:312-315.
18. Bito LZ, Camras CB, Glenwood GG, Resul B. The ocular hypotensive effects and side effects of prostaglandins on the eyes of experimental animals. In: Bito L, Stjernschantz J, eds. The Ocular Effects of Prostaglandins and Other Eicosanoids. New York: Alan R. Liss; 1989:349-368.
19. Bazan HEP, Reddy STK, Lin N. Platelet-activating factor (PAF) accumulation correlates with injury in the cornea. Exp Eye Res. 1991;52:481-491.
20. Bazan HEP, Tao Y, Bazan NG. Platelet-activating factor induces collagenase expression in corneal epithelial cells. Proc Natl Acad Sci USA. 1993;90:8678-8682.
21. Tao Y, Bazan HEP, Bazan NG. Platelet-activating factor induces the expression of metalloproteinases-1 and -9, but not -2 or -3, in the corneal epithelium. Invest Ophthalmol Vis Sci. 1995;36:345-354.
22. Tao Y, Bazan HEP, Bazan NG. Platelet-activating factor enhances urokinase-type plasminogen activation (UPA) gene expression in corneal epithelium. Invest Ophthalmol Vis Sci. 1996;37:2037-2046.
23. 2/cyclooxygenase cascade in the rabbit cornea. Curr Eye Res. 1995;14:769-775.
24. Honda Z, Nakamura M, Ichiro M, et al. Cloning by functional expression of platelet-activating factor receptor from guinea-pig lung. Nature. 1991;349:342-346.
25. Shukla SD. Platelet-activating factor and signal transduction mechanisms. FASEB J. 1992;6:2296-2301.
26. Chomczyski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenolchloroform extraction. Anal Biochem. 1987;162:156-159
27. DeCoster MA, Koenig ML, Hunter JC, Tortella FC. Calcium dynamics in neurons treated with toxic and non-toxic concentrations of glutamate. NeuroReport. 1992;3:773-776.
28. 2 synthesis. Invest Ophthalmol Vis Sci. 1996;37:1294-1301.
29. Kaufmann WE, Worley PF, Pegg J, Bremer M, Isakson P. The COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex. Proc Natl Acad Sci USA. 1996;93:2317-2321.
30. Marcheselli VL, Bazan NG. Sustained induction of prostaglandin endoperoxide synthase-2 by seizures in hippocampus. J Biol Chem. 1996;271:24794-24799.
31. Hurst J, Bazan HEP. Activation of the phospholipase/ cyclooxygenase cascade in the rabbit cornea by platelet-activating factor is challenged by PAF receptor antagonists. J Ocular Pharmacol. 1995;11:329-337.
32. Smith WL, DeWitt DL. Prostaglandin endoperoxide H synthases-1 and -2. Adv Immunol. 1995;62:167-215.
33. 2+] and phospholipase activity in mesangial cells. Am Physiol Soc. 1988;F87-F94.
34. Selak MA, Smith JB. Platelet-activating factor-induced calcium mobilization in human platelets and neutrophils: Effects of PAF-acether antagonists. J Lipid Med. 1989;1:125-137.
35. Kornecki E, Ehrlich YH. Neuroregulatory and neuropathological actions of the ether-phospholipid platelet-activating factor. Science. 1988;240:1792-1794.
36. Mazer B, Domenico J, Hiroyasu S, Gelfand EW. Platelet-activating factor induces an increase in intracellular calcium and expression of regulatory genes in human B lymphoblastoid cells. J Immunol. 1991; 146:1914-1920.
37. Ali H, Richardson RM, Tomhave ED, DuBose RA, Bodduluri H, Snyderman R. Regulation of stably transfected platelet activating factor receptor in RBL-2H3 cells. J Biol Chem. 1994;269:24557-24563.
38. 2 and distal prostaglandin synthase 1. J Biol Chem. 1996; 271:186-191.
39. Marcheselli V, Rossowska M, Domingo M, Braquet P, Bazan NG. Distinct platelet-activating factor binding sites in synaptic endings and in intracellular membranes of rat cerebral cortex. J Biol Chem. 1990;265:9140-9145.
40. Chang MS, Yang R, O'Day DM, Breyer MD, DuBois RN. Cloning of rabbit cyclooxygenase-2 and the time course of its induction during fungal endophthalmitis. Invest Ophthalmol Vis Sci. 1996;(S)37:55478.
41. Xie W, Herschman HR. V-src induces prostaglandin synthase 2 gene expression by activation of the c-Jun N-terminal kinase and the c-Jun transcription factor. J Biol Chem. 1995;270:27622-27628.
42. Schwaninger M, Blume R, Oetjen E, Lux G, Knepel W. Inhibition of cAMP-responsive element-mediated gene transcription by cyclosporin A and FK506 after membrane depolarization. J Biol Chem. 1995; 268:23111-23115.
43. Bazan NG, Fletcher BS, Herschman HR, Mukherjee PK. Platelet-activating factor and retinoic acid synergistically activate the inducible prostaglandin synthase gene. Proc Natl Acad Sci USA. 1994;91:5252-5256.
44. Tsujii M, DuBois RN. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell. 1995;83:493-501.
45. Srinivasan BD, Kulkarni PS. The effect of steroidal and nonsteroidal anti-inflammatory agents on corneal re-epithelialization. Invest Ophthalmol Vis Sci. 1981; 20:688-691.