-
1
-
-
0025500378
-
Mechanisms and kinetics of monoclonal antibody synthesis and secretion in synchronous and asynchronous hybridoma cell cultures
-
Al-Rubeai M, Emery AN (1990) Mechanisms and kinetics of monoclonal antibody synthesis and secretion in synchronous and asynchronous hybridoma cell cultures. J Biotechnol 16:67-86
-
(1990)
J Biotechnol
, vol.16
, pp. 67-86
-
-
Al-Rubeai, M.1
Emery, A.N.2
-
2
-
-
0027024341
-
Specific antibody productivity and the cell cycle comparisons of batch, continuous and perfusion cultures
-
Al-Rubeai M, Emery AN, Chalder S, Jan DC (1992a) Specific antibody productivity and the cell cycle comparisons of batch, continuous and perfusion cultures. Cytotechnology 9:85-87
-
(1992)
Cytotechnology
, vol.9
, pp. 85-87
-
-
Al-Rubeai, M.1
Emery, A.N.2
Chalder, S.3
Jan, D.C.4
-
3
-
-
0026575910
-
The effect of Pluronic F-68 on hybridoma cells in continuous culture
-
Al-Rubeai M, Emery AN, Chalder S (1992b) The effect of Pluronic F-68 on hybridoma cells in continuous culture. Appl Microbiol Biotechnol 37:44-45
-
(1992)
Appl Microbiol Biotechnol
, vol.37
, pp. 44-45
-
-
Al-Rubeai, M.1
Emery, A.N.2
Chalder, S.3
-
4
-
-
0029636268
-
Cell cycle and cell size dependence of susceptibility to hydrodynamic forces
-
Al-Rubeai M, Singh RP, Emery AN, Zhang Z (1995) Cell cycle and cell size dependence of susceptibility to hydrodynamic forces. Biotechnol Bioeng 46:88-92
-
(1995)
Biotechnol Bioeng
, vol.46
, pp. 88-92
-
-
Al-Rubeai, M.1
Singh, R.P.2
Emery, A.N.3
Zhang, Z.4
-
5
-
-
0028485585
-
Hybridoma growth and monoclonal antibody production in a dialysis prefusion system
-
Amos B, Al-Rubeai M, Emery AN (1994) Hybridoma growth and monoclonal antibody production in a dialysis prefusion system. Enzyme Microb Technol 16:688-695
-
(1994)
Enzyme Microb Technol
, vol.16
, pp. 688-695
-
-
Amos, B.1
Al-Rubeai, M.2
Emery, A.N.3
-
7
-
-
1542410260
-
Uncoupling of cell growth and proliferation results in enhancement of productivity in p21 arrested CHO cells
-
Bi J-X, Shuttleworth J, Al-Rubeai M (2004) Uncoupling of cell growth and proliferation results in enhancement of productivity in p21 arrested CHO cells. Biotechnol Bioeng 85:741-749
-
(2004)
Biotechnol Bioeng
, vol.85
, pp. 741-749
-
-
Bi, J.-X.1
Shuttleworth, J.2
Al-Rubeai, M.3
-
8
-
-
0025428078
-
Industrial production of monoclonal antibodies and theraputic protiens by dialysis fermentation
-
Comer M, Kearns M, Wahl J, Munster M, Lorenz T, Szperalski B, Behrendt U, Brunner H (1990) Industrial production of monoclonal antibodies and theraputic protiens by dialysis fermentation. Cytotechnol 3:295-299
-
(1990)
Cytotechnol
, vol.3
, pp. 295-299
-
-
Comer, M.1
Kearns, M.2
Wahl, J.3
Munster, M.4
Lorenz, T.5
Szperalski, B.6
Behrendt, U.7
Brunner, H.8
-
9
-
-
0032483461
-
Ectopic p21(WAF1) expression induces differentiation-specific cell cycle changes in PC12 cells characteristic of nerve growth factor treatment
-
Erhardt JA, Pittman RN (1998) Ectopic p21(WAF1) expression induces differentiation-specific cell cycle changes in PC12 cells characteristic of nerve growth factor treatment. J Biol Chem 273:23517-23523
-
(1998)
J Biol Chem
, vol.273
, pp. 23517-23523
-
-
Erhardt, J.A.1
Pittman, R.N.2
-
11
-
-
0031911956
-
Long term cultivation of immortalised mouse hepatocytes in high cell density, fixed-bed reactor
-
Fassnacht D, Rossing S, Strange J, Porter R (1998a) Long term cultivation of immortalised mouse hepatocytes in high cell density, fixed-bed reactor. Biotechnol Techniq 12:25-30
-
(1998)
Biotechnol Techniq
, vol.12
, pp. 25-30
-
-
Fassnacht, D.1
Rossing, S.2
Strange, J.3
Porter, R.4
-
12
-
-
0031899540
-
Effect of Bcl-2 expression on hybridoma cell growth in serum supplemented, protein free and diluted media
-
Fassnacht D, Rossing S, Franek F, Al-Rubeai M, Porter R (1998b) Effect of Bcl-2 expression on hybridoma cell growth in serum supplemented, protein free and diluted media. Cytotechnol 26:219-225
-
(1998)
Cytotechnol
, vol.26
, pp. 219-225
-
-
Fassnacht, D.1
Rossing, S.2
Franek, F.3
Al-Rubeai, M.4
Porter, R.5
-
13
-
-
0025756428
-
Nucleosomes occurring in protein free hybridoma cell cultures. Evidence for programmed cell death
-
Franek F, Dolnikova J (1991) Nucleosomes occurring in protein free hybridoma cell cultures. Evidence for programmed cell death. FEBS Lett 248:285-287
-
(1991)
FEBS Lett
, vol.248
, pp. 285-287
-
-
Franek, F.1
Dolnikova, J.2
-
14
-
-
0014661176
-
Spin filter culture: The propagation of mammalian cells in suspension
-
Himmelfarb P, Thayer PS, Martin HE (1969) Spin filter culture: the propagation of mammalian cells in suspension. Science 164:555-557
-
(1969)
Science
, vol.164
, pp. 555-557
-
-
Himmelfarb, P.1
Thayer, P.S.2
Martin, H.E.3
-
15
-
-
0027935405
-
Molecular cloning, sequencing, chromosomal localization and expression of mouse p21 (Waf1)
-
Huppi K, Siwarski D, Dosik J, Michieli P, Chedid M, Reed S, Mock B, Givol D, Mushinski JF (1994) Molecular cloning, sequencing, chromosomal localization and expression of mouse p21 (Waf1). Oncogene 9:3017-3020
-
(1994)
Oncogene
, vol.9
, pp. 3017-3020
-
-
Huppi, K.1
Siwarski, D.2
Dosik, J.3
Michieli, P.4
Chedid, M.5
Reed, S.6
Mock, B.7
Givol, D.8
Mushinski, J.F.9
-
16
-
-
0032726415
-
Role of Ca, Mg and K ions in determining apoptosis and extent of suppression afforded by bcl-2 during hybridoma cell culture
-
Ishaque A, Al-Rubeai M (1999) Role of Ca, Mg and K ions in determining apoptosis and extent of suppression afforded by bcl-2 during hybridoma cell culture. Apoptosis 4:335-355
-
(1999)
Apoptosis
, vol.4
, pp. 335-355
-
-
Ishaque, A.1
Al-Rubeai, M.2
-
17
-
-
0036016922
-
Role of vitamins in determining apoptosis and extent of suppression by bcl-2 during hybridoma cell culture
-
Ishaque A, Al-Rubeai M (2002) Role of vitamins in determining apoptosis and extent of suppression by bcl-2 during hybridoma cell culture. Apoptosis 7:231-239
-
(2002)
Apoptosis
, vol.7
, pp. 231-239
-
-
Ishaque, A.1
Al-Rubeai, M.2
-
18
-
-
0029048389
-
Overexpression of Bcl-2, apoptosis suppressing gene: Prolonged viable culture period of hybridoma and enhanced antibody production
-
Itoh Y, Ueda H, Suzuki E (1995) Overexpression of Bcl-2, apoptosis suppressing gene: prolonged viable culture period of hybridoma and enhanced antibody production. Biotechnol Bioeng 48:118-122
-
(1995)
Biotechnol Bioeng
, vol.48
, pp. 118-122
-
-
Itoh, Y.1
Ueda, H.2
Suzuki, E.3
-
19
-
-
0001061059
-
Introducing spin filter eliminates hydrodynamic damage to hybridomas in bioreactor
-
Jan DCH, Emery AN, Al-rubeai M (1993) Introducing spin filter eliminates hydrodynamic damage to hybridomas in bioreactor. Biotechnol Techniq 7:351-356
-
(1993)
Biotechnol Techniq
, vol.7
, pp. 351-356
-
-
Jan, D.C.H.1
Emery, A.N.2
Al-Rubeai, M.3
-
20
-
-
0037454718
-
Effect of shear stress on expression of a recombinant protein by Chinese hamster ovary cells
-
Keane JT (2003) Effect of shear stress on expression of a recombinant protein by Chinese hamster ovary cells. Biotechnol Bioeng 81:211-220
-
(2003)
Biotechnol Bioeng
, vol.81
, pp. 211-220
-
-
Keane, J.T.1
-
21
-
-
0029173973
-
Adaptation of cholesterol-requiring NS0 mouse myeloma cells to high density growth in a fully defined protein-free and cholesterol-free culture medium
-
Keen MJ, Steward TW (1995) Adaptation of cholesterol-requiring NS0 mouse myeloma cells to high density growth in a fully defined protein-free and cholesterol-free culture medium. Cyotechnol 17:203-211
-
(1995)
Cyotechnol
, vol.17
, pp. 203-211
-
-
Keen, M.J.1
Steward, T.W.2
-
22
-
-
84984086633
-
The cultivation of animal cells at controlled dissolved oxygen partial pressure
-
Kilburn DG, Webb FC (1968) The cultivation of animal cells at controlled dissolved oxygen partial pressure. Biotechnol Bioeng 10:801-814
-
(1968)
Biotechnol Bioeng
, vol.10
, pp. 801-814
-
-
Kilburn, D.G.1
Webb, F.C.2
-
23
-
-
0021267816
-
Serum-free medium for hybridoma and parental myeloma cell cultivation: A novel composition of growth-supporting substances
-
Kovar J, Franek F (1984) Serum-free medium for hybridoma and parental myeloma cell cultivation: a novel composition of growth-supporting substances. Immunol Lett 7:339-345
-
(1984)
Immunol Lett
, vol.7
, pp. 339-345
-
-
Kovar, J.1
Franek, F.2
-
24
-
-
0026457919
-
Influence of shear stress on adherent mammalian cells during division
-
Ludwig A (1992) Influence of shear stress on adherent mammalian cells during division. Biotechnol Lett 14:881-884
-
(1992)
Biotechnol Lett
, vol.14
, pp. 881-884
-
-
Ludwig, A.1
-
25
-
-
0030440856
-
Bcl-2 inhibits apoptosis and extends recombinant protein production in cells infected with sinbis viral vectors
-
Mastrangelo AJ, Hardwick JM, Betenbaugh MJ (1996) Bcl-2 inhibits apoptosis and extends recombinant protein production in cells infected with sinbis viral vectors. Cytotechnology 22:169-178
-
(1996)
Cytotechnology
, vol.22
, pp. 169-178
-
-
Mastrangelo, A.J.1
Hardwick, J.M.2
Betenbaugh, M.J.3
-
26
-
-
0028765762
-
Induction of apoptosis in nutrient deprived cultures of hybridoma and myeloma cells
-
Mercille S, Massie B (1994) Induction of apoptosis in nutrient deprived cultures of hybridoma and myeloma cells. Biotechnol Bioeng 44:1140-1154
-
(1994)
Biotechnol Bioeng
, vol.44
, pp. 1140-1154
-
-
Mercille, S.1
Massie, B.2
-
27
-
-
0343035687
-
Bcl-2 expression in Spodoptera frugiperda Sf9 and Trichoplusia ni BT-Tn-5B1-4 insect cell: Effect on recombinant protein expression and cell viability
-
Mitchell-Logean C, Murhammer DW (1997) Bcl-2 expression in Spodoptera frugiperda Sf9 and Trichoplusia ni BT-Tn-5B1-4 insect cell: effect on recombinant protein expression and cell viability. Biotechnol Bioeng 56:380-388
-
(1997)
Biotechnol Bioeng
, vol.56
, pp. 380-388
-
-
Mitchell-Logean, C.1
Murhammer, D.W.2
-
28
-
-
0028291485
-
High density cultivation of hybridoma in charged porous carriers
-
Ong CP, Portner R, Markl H, Yamazaki Y, Yasuda K, Matsumura M (1994) High density cultivation of hybridoma in charged porous carriers. Biotechnol 34:259-268
-
(1994)
Biotechnol
, vol.34
, pp. 259-268
-
-
Ong, C.P.1
Portner, R.2
Markl, H.3
Yamazaki, Y.4
Yasuda, K.5
Matsumura, M.6
-
30
-
-
0032442810
-
Variable functions of bcl-2 in mediating bioreactor stress- induced apoptosis in hybridoma cells
-
Perani A, Singh RP, Chauhan R, Al-Rubeai M (1999) Variable functions of bcl-2 in mediating bioreactor stress- induced apoptosis in hybridoma cells. Cytotechnology 28:177-188
-
(1999)
Cytotechnology
, vol.28
, pp. 177-188
-
-
Perani, A.1
Singh, R.P.2
Chauhan, R.3
Al-Rubeai, M.4
-
31
-
-
0343812075
-
Kinetic studies on hybridoma cells immobilised in fixed-bed reactors
-
Portner R, Rossing S, Koop M, Ludemann I (1997) Kinetic studies on hybridoma cells immobilised in fixed-bed reactors. Biotechnol Bioeng 55:535-541
-
(1997)
Biotechnol Bioeng
, vol.55
, pp. 535-541
-
-
Portner, R.1
Rossing, S.2
Koop, M.3
Ludemann, I.4
-
33
-
-
0031554004
-
Prevention of hybridoma cell death by Bcl-2 during sub optimal culture conditions
-
Simpson NH, Milner AN, Al-Rubeai M (1997) Prevention of hybridoma cell death by Bcl-2 during sub optimal culture conditions. Biotechnol Bioeng 54:1-16
-
(1997)
Biotechnol Bioeng
, vol.54
, pp. 1-16
-
-
Simpson, N.H.1
Milner, A.N.2
Al-Rubeai, M.3
-
34
-
-
0033587794
-
Bcl-2 over-expression reduces growth rate and prolongs G1 phase in continuous chemostat cultures of hybridoma cells
-
Simpson NH, Singh RP, Emery AN, Al-Rubeai M (1999) Bcl-2 over-expression reduces growth rate and prolongs G1 phase in continuous chemostat cultures of hybridoma cells. Biotechnol Bioeng 64:174-186
-
(1999)
Biotechnol Bioeng
, vol.64
, pp. 174-186
-
-
Simpson, N.H.1
Singh, R.P.2
Emery, A.N.3
Al-Rubeai, M.4
-
35
-
-
0033846848
-
Adaptation of mammalian cells to growth in serum free media
-
Sinacore M, Drapeau D, Adamson SR (2000) Adaptation of mammalian cells to growth in serum free media. Mol Biotechnol 15:249-257
-
(2000)
Mol Biotechnol
, vol.15
, pp. 249-257
-
-
Sinacore, M.1
Drapeau, D.2
Adamson, S.R.3
-
37
-
-
21644458683
-
Suppression of apoptosis in perfusion culture of myeloma NS0 enhances cell growth but reduces antibody productivity
-
Tey BT, Al-Rubeai M (2004) Suppression of apoptosis in perfusion culture of myeloma NS0 enhances cell growth but reduces antibody productivity. Apoptosis 9:843-852
-
(2004)
Apoptosis
, vol.9
, pp. 843-852
-
-
Tey, B.T.1
Al-Rubeai, M.2
-
38
-
-
0034607272
-
Influence of Bcl-2 on cell death during the cultivation of a Chinese hamster ovary cell line expressing a chimeric antibody
-
Tey BT, Singh L, Piredda M, Al-Rubeai M (2000a) Influence of Bcl-2 on cell death during the cultivation of a Chinese hamster ovary cell line expressing a chimeric antibody. Biotechnol Bioeng 68:31-43
-
(2000)
Biotechnol Bioeng
, vol.68
, pp. 31-43
-
-
Tey, B.T.1
Singh, L.2
Piredda, M.3
Al-Rubeai, M.4
-
39
-
-
0034607272
-
Influence of Bcl-2 on cell death during cultivation of a Chinese Hamster Ovary cell line expressing a chimeric antibody
-
Tey BT, Singh RP, Piredda L, Piacentini M, Al-Rubeai M (2000b) Influence of Bcl-2 on cell death during cultivation of a Chinese Hamster Ovary cell line expressing a chimeric antibody. Biotechnol Bioeng 68:31-43
-
(2000)
Biotechnol Bioeng
, vol.68
, pp. 31-43
-
-
Tey, B.T.1
Singh, R.P.2
Piredda, L.3
Piacentini, M.4
Al-Rubeai, M.5
-
40
-
-
0022679115
-
A radial flow hollow fiber reactor for large scale culture of mammalian cells
-
Tharakan JP, Chau PC (1986) A radial flow hollow fiber reactor for large scale culture of mammalian cells. Biotechnol Bioeng 28:329-342
-
(1986)
Biotechnol Bioeng
, vol.28
, pp. 329-342
-
-
Tharakan, J.P.1
Chau, P.C.2
-
41
-
-
0037021802
-
Regulation of cell cycle and productivity in NS0 cells by the over-expression of p21
-
Watanabe S, Shuttleworth J, Al-Rubeai M (2002) Regulation of cell cycle and productivity in NS0 cells by the over-expression of p21. Biotechnol Bioeng 77:1-7
-
(2002)
Biotechnol Bioeng
, vol.77
, pp. 1-7
-
-
Watanabe, S.1
Shuttleworth, J.2
Al-Rubeai, M.3
-
42
-
-
0031974591
-
Ammonium ion transport by the Na+ K+ 2C1- co transporter induces apoptosis in hybridoma cells
-
Westlund A, Haggstrom L (1998) Ammonium ion transport by the Na+ K+ 2C1- co transporter induces apoptosis in hybridoma cells. Biotechnol Lett 20:87-90
-
(1998)
Biotechnol Lett
, vol.20
, pp. 87-90
-
-
Westlund, A.1
Haggstrom, L.2
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