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Volumn 1782, Issue 1, 2008, Pages 1-9

Protein kinase X (PRKX) can rescue the effects of polycystic kidney disease-1 gene (PKD1) deficiency

Author keywords

Adhesion; Cyclic AMP; Developmental biology; Differentiation; Migration; Morphogenesis; Renal cystic disease

Indexed keywords

CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; HYBRID PROTEIN; LENTIVIRUS VECTOR; POLYCYSTIN 1; PROTEIN KINASE X; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

EID: 39149102488     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2007.09.003     Document Type: Article
Times cited : (20)

References (41)
  • 1
    • 0027925829 scopus 로고
    • Autosomal dominant polycystic kidney disease
    • Gabow P. Autosomal dominant polycystic kidney disease. N. Engl. J. Med. 329 (1993) 332
    • (1993) N. Engl. J. Med. , vol.329 , pp. 332
    • Gabow, P.1
  • 2
    • 0347357836 scopus 로고    scopus 로고
    • Polycystic kidney disease
    • Wilson P.D. Polycystic kidney disease. N. Engl. J. Med. 350 (2004) 151
    • (2004) N. Engl. J. Med. , vol.350 , pp. 151
    • Wilson, P.D.1
  • 3
    • 0037047061 scopus 로고    scopus 로고
    • PRKX, a phylogenetically and functionally distinct cAMP-dependent protein kinase, activates renal epithelial cell migration and morphogenesis
    • Li X., Li H.P., Amsler K., Hyink D., Wilson P.D., and Burrow C.R. PRKX, a phylogenetically and functionally distinct cAMP-dependent protein kinase, activates renal epithelial cell migration and morphogenesis. Proc. Natl. Acad. Sci. 99 (2002) 9260
    • (2002) Proc. Natl. Acad. Sci. , vol.99 , pp. 9260
    • Li, X.1    Li, H.P.2    Amsler, K.3    Hyink, D.4    Wilson, P.D.5    Burrow, C.R.6
  • 4
    • 0033532582 scopus 로고    scopus 로고
    • Identification of phosphorylation sites in the PKD1-encoded protein C-terminal domain
    • Li H.P., Geng L., Burrow C.R., and Wilson P.D. Identification of phosphorylation sites in the PKD1-encoded protein C-terminal domain. Biochem. Biophys. Res. Commun. 259 (1999) 356
    • (1999) Biochem. Biophys. Res. Commun. , vol.259 , pp. 356
    • Li, H.P.1    Geng, L.2    Burrow, C.R.3    Wilson, P.D.4
  • 5
    • 33751327780 scopus 로고    scopus 로고
    • Epithelial cell polarity and disease
    • Wilson P.D. Epithelial cell polarity and disease. Am. J. Physiol. 272 (1997) F434
    • (1997) Am. J. Physiol. , vol.272
    • Wilson, P.D.1
  • 9
    • 25844515578 scopus 로고    scopus 로고
    • Disruption of polycystin-1 function interferes with branching morphogenesis of the ureteric bud in developing mouse kidneys
    • Polgar K., Burrow C.R., Hyink D.P., Fernandez H., Thornton K., Li X., Gusella G.L., and Wilson P.D. Disruption of polycystin-1 function interferes with branching morphogenesis of the ureteric bud in developing mouse kidneys. Dev. Biol. 286 (2005) 16
    • (2005) Dev. Biol. , vol.286 , pp. 16
    • Polgar, K.1    Burrow, C.R.2    Hyink, D.P.3    Fernandez, H.4    Thornton, K.5    Li, X.6    Gusella, G.L.7    Wilson, P.D.8
  • 10
    • 0142106807 scopus 로고    scopus 로고
    • Role of polycystins in renal tubulogenesis
    • Boletta A., and Germino G.G. Role of polycystins in renal tubulogenesis. Trends Cell Biol. 13 (2003) 484
    • (2003) Trends Cell Biol. , vol.13 , pp. 484
    • Boletta, A.1    Germino, G.G.2
  • 11
    • 0141451943 scopus 로고    scopus 로고
    • Combination treatment of PKD utilizing dual inhibition of EGF-receptor activity and ligand bioavailability
    • Sweeney Jr. W.E., Hamahira K., Sweeney J., Garcia-Gatrell M., Frost P., and Avner E.D. Combination treatment of PKD utilizing dual inhibition of EGF-receptor activity and ligand bioavailability. Kidney Int. 64 (2003) 1310
    • (2003) Kidney Int. , vol.64 , pp. 1310
    • Sweeney Jr., W.E.1    Hamahira, K.2    Sweeney, J.3    Garcia-Gatrell, M.4    Frost, P.5    Avner, E.D.6
  • 12
    • 4644293032 scopus 로고    scopus 로고
    • Therapies to slow polycystic kidney disease
    • Torres V.E. Therapies to slow polycystic kidney disease. Nephron. Exp. Nephrol. 98 (2004) e1
    • (2004) Nephron. Exp. Nephrol. , vol.98
    • Torres, V.E.1
  • 14
    • 0345329652 scopus 로고    scopus 로고
    • Does cAMP enhance cyst formation both in polycystic kidney disease (ADPKD) cells and normal renal cells?
    • Hanaoka K., Devuyst O., Schwiebert E., and Guggino W.B. Does cAMP enhance cyst formation both in polycystic kidney disease (ADPKD) cells and normal renal cells?. JASN B. (1997) 372a
    • (1997) JASN B.
    • Hanaoka, K.1    Devuyst, O.2    Schwiebert, E.3    Guggino, W.B.4
  • 16
    • 0032956458 scopus 로고    scopus 로고
    • ATP release mechanisms in primary cultures of epithelia derived from the cysts of polycystic kidney
    • Wilson P.D., Hovater J.S., Casey C.C., Fortenberry J.A., and Schwiebert E.M. ATP release mechanisms in primary cultures of epithelia derived from the cysts of polycystic kidney. JASN 10 (1999) 218
    • (1999) JASN , vol.10 , pp. 218
    • Wilson, P.D.1    Hovater, J.S.2    Casey, C.C.3    Fortenberry, J.A.4    Schwiebert, E.M.5
  • 17
    • 0036083611 scopus 로고    scopus 로고
    • cAMP-dependent protein kinase and proliferation differ in normal and polycystic kidney epithelia
    • Marfella-Scivittaro C., Quinones A., and Orellana S.A. cAMP-dependent protein kinase and proliferation differ in normal and polycystic kidney epithelia. Am. J. Physiol. 282 (2002) C693
    • (2002) Am. J. Physiol. , vol.282
    • Marfella-Scivittaro, C.1    Quinones, A.2    Orellana, S.A.3
  • 18
    • 0033605139 scopus 로고    scopus 로고
    • PrKX is a novel catalytic subunit of the cAMP-dependent protein kinase regulated by the regulatory subunit type I
    • Zimmermann B., Chiorini J.A., Ma Y., Kotin R.M., and Herberg F.W. PrKX is a novel catalytic subunit of the cAMP-dependent protein kinase regulated by the regulatory subunit type I. J. Biol. Chem. 274 (1999) 5370
    • (1999) J. Biol. Chem. , vol.274 , pp. 5370
    • Zimmermann, B.1    Chiorini, J.A.2    Ma, Y.3    Kotin, R.M.4    Herberg, F.W.5
  • 19
    • 2942534582 scopus 로고    scopus 로고
    • Polycystic kidney disease: new understanding in the pathogenesis
    • Wilson P.D. Polycystic kidney disease: new understanding in the pathogenesis. Int. J. Biochem. Cell Biol. 36 (2004) 1868
    • (2004) Int. J. Biochem. Cell Biol. , vol.36 , pp. 1868
    • Wilson, P.D.1
  • 20
    • 0029034123 scopus 로고
    • Multiple signal transduction pathways regulate discoidin I gene expression in Dictyostelium discoideum
    • Blusch J., Alexander S., and Nellen W. Multiple signal transduction pathways regulate discoidin I gene expression in Dictyostelium discoideum. Differentiation 58 (1995) 253
    • (1995) Differentiation , vol.58 , pp. 253
    • Blusch, J.1    Alexander, S.2    Nellen, W.3
  • 21
    • 0033574983 scopus 로고    scopus 로고
    • Identification of the major site of in vitro PKA phosphorylation in the polycystin-1 C-terminal cytosolic domain
    • Parnell S.C., Magenheimer B.S., Maser R.L., and Calvet J.P. Identification of the major site of in vitro PKA phosphorylation in the polycystin-1 C-terminal cytosolic domain. Biochem. Biophys. Res. Commun. 259 (1999) 539
    • (1999) Biochem. Biophys. Res. Commun. , vol.259 , pp. 539
    • Parnell, S.C.1    Magenheimer, B.S.2    Maser, R.L.3    Calvet, J.P.4
  • 22
    • 0026571382 scopus 로고
    • Relationship between abnormal extracellular matrix and excessive growth of human adult polycystic kidney disease epithelia
    • Wilson P.D., Hreniuk D., and Gabow P. Relationship between abnormal extracellular matrix and excessive growth of human adult polycystic kidney disease epithelia. J. Cell. Physiol. 150 (1992) 360
    • (1992) J. Cell. Physiol. , vol.150 , pp. 360
    • Wilson, P.D.1    Hreniuk, D.2    Gabow, P.3
  • 23
    • 0037213437 scopus 로고    scopus 로고
    • Morphogenesis during mouse embryonic kidney explant culture
    • Gupta I.R., Lapointe M., and Yu O.H. Morphogenesis during mouse embryonic kidney explant culture. Kidney Int. 63 (2003) 365
    • (2003) Kidney Int. , vol.63 , pp. 365
    • Gupta, I.R.1    Lapointe, M.2    Yu, O.H.3
  • 25
    • 0032831465 scopus 로고    scopus 로고
    • The PKD1 gene product, "polycystin-1," is a tyrosine-phosphorylated protein that colocalizes with alpha2beta1-integrin in focal clusters in adherent renal epithelia
    • Wilson P.D., Geng L., Li X., and Burrow C.R. The PKD1 gene product, "polycystin-1," is a tyrosine-phosphorylated protein that colocalizes with alpha2beta1-integrin in focal clusters in adherent renal epithelia. Lab. Invest. 79 (1999) 1311
    • (1999) Lab. Invest. , vol.79 , pp. 1311
    • Wilson, P.D.1    Geng, L.2    Li, X.3    Burrow, C.R.4
  • 26
    • 0034672628 scopus 로고    scopus 로고
    • Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation
    • Geng L., Burrow C.R., Li H., and Wilson P.D. Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation. BBA 1535 (2000) 21
    • (2000) BBA , vol.1535 , pp. 21
    • Geng, L.1    Burrow, C.R.2    Li, H.3    Wilson, P.D.4
  • 27
    • 0027409422 scopus 로고
    • Mutations in the catalytic subunit of the cAMP-dependent protein kinase interfere with holoenzyme formation without disrupting inhibition by protein kinase inhibitor
    • Orellana S.A., Amieux P.S., Zhao X., and McKnight G.S. Mutations in the catalytic subunit of the cAMP-dependent protein kinase interfere with holoenzyme formation without disrupting inhibition by protein kinase inhibitor. J. Biol. Chem. 268 (1993) 6843
    • (1993) J. Biol. Chem. , vol.268 , pp. 6843
    • Orellana, S.A.1    Amieux, P.S.2    Zhao, X.3    McKnight, G.S.4
  • 28
    • 0029996147 scopus 로고    scopus 로고
    • In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
    • Naldini L., Blomer U., Gage F.H., Trono D., and Verma I.M. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272 (1996) 263
    • (1996) Science , vol.272 , pp. 263
    • Naldini, L.1    Blomer, U.2    Gage, F.H.3    Trono, D.4    Verma, I.M.5
  • 30
    • 0029122255 scopus 로고
    • Renal proximal tubular epithelium from patients with nephropathic cystinosis: immortalized cell lines as in vitro model systems
    • Racusen L.C., Wilson P.D., Hartz P.A., Fivush B.A., and Burrow C.R. Renal proximal tubular epithelium from patients with nephropathic cystinosis: immortalized cell lines as in vitro model systems. Kidney Int. 48 (1995) 536
    • (1995) Kidney Int. , vol.48 , pp. 536
    • Racusen, L.C.1    Wilson, P.D.2    Hartz, P.A.3    Fivush, B.A.4    Burrow, C.R.5
  • 32
    • 0030932681 scopus 로고    scopus 로고
    • FISH localization of the human Y-homolog of protein kinase PRKX (PRKY) to Yp11.2 and two pseudogenes to 15q26 and Xq12->q13
    • Schiebel K., Mertz A., Winkelmann M., Glaser B., Schempp W., and Rappold G. FISH localization of the human Y-homolog of protein kinase PRKX (PRKY) to Yp11.2 and two pseudogenes to 15q26 and Xq12->q13. Cytogenet. Cell Genet. 76 (1997) 49
    • (1997) Cytogenet. Cell Genet. , vol.76 , pp. 49
    • Schiebel, K.1    Mertz, A.2    Winkelmann, M.3    Glaser, B.4    Schempp, W.5    Rappold, G.6
  • 34
    • 0026485791 scopus 로고
    • DdPK3, which plays essential roles during Dictyostelium development, encodes the catalytic subunit of cAMP-dependent protein kinase
    • Mann S.K., Yonemoto W.M., Taylor S.S., and Firtel R.A. DdPK3, which plays essential roles during Dictyostelium development, encodes the catalytic subunit of cAMP-dependent protein kinase. Proc. Natl. Acad. Sci. U. S. A. 89 (1992) 10701
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 10701
    • Mann, S.K.1    Yonemoto, W.M.2    Taylor, S.S.3    Firtel, R.A.4
  • 35
    • 0027363994 scopus 로고
    • An unusual catalytic subunit for the cAMP-dependent protein kinase of Dictyostelium discoideum
    • Anjard C., Etchebehere L., Pinaud S., Veron M., and Reymond C.D. An unusual catalytic subunit for the cAMP-dependent protein kinase of Dictyostelium discoideum. Biochemistry 32 (1993) 9532
    • (1993) Biochemistry , vol.32 , pp. 9532
    • Anjard, C.1    Etchebehere, L.2    Pinaud, S.3    Veron, M.4    Reymond, C.D.5
  • 36
    • 33645956213 scopus 로고    scopus 로고
    • Protein kinase X activates ureteric bud branching morphogenesis in developing mouse metanephric kidney
    • Li X., Hyink D., Polgar K., Gusella G.L., Wilson P.D., and Burrow C.R. Protein kinase X activates ureteric bud branching morphogenesis in developing mouse metanephric kidney. JASN 16 (2005) 3543
    • (2005) JASN , vol.16 , pp. 3543
    • Li, X.1    Hyink, D.2    Polgar, K.3    Gusella, G.L.4    Wilson, P.D.5    Burrow, C.R.6
  • 38
    • 33646155954 scopus 로고    scopus 로고
    • Identification of an N-terminal glycogen synthase kinase 3 phosphorylation site which regulates the functional localization of polycystin-2 in vivo and in vitro
    • Streets A.J., Moon D.J., Kane M.E., Obara T., and Ong A.C. Identification of an N-terminal glycogen synthase kinase 3 phosphorylation site which regulates the functional localization of polycystin-2 in vivo and in vitro. Hum. Mol. Genet. 15 (2006) 1465
    • (2006) Hum. Mol. Genet. , vol.15 , pp. 1465
    • Streets, A.J.1    Moon, D.J.2    Kane, M.E.3    Obara, T.4    Ong, A.C.5
  • 39
    • 0032820782 scopus 로고    scopus 로고
    • Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration
    • Sieg D.J., Hauck C.R., and Schlaepfer D.D. Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration. J. Cell Sci. 112 (1999) 2677
    • (1999) J. Cell Sci. , vol.112 , pp. 2677
    • Sieg, D.J.1    Hauck, C.R.2    Schlaepfer, D.D.3
  • 40
    • 0034635442 scopus 로고    scopus 로고
    • Characterization of structural features that mediate the tethering of Caenorhabditis elegans protein kinase A to a novel A kinase anchor protein. Insights into the anchoring of PKAI isoforms
    • Angelo R.G., and Rubin C.S. Characterization of structural features that mediate the tethering of Caenorhabditis elegans protein kinase A to a novel A kinase anchor protein. Insights into the anchoring of PKAI isoforms. J. Biol. Chem. 275 (2000) 4351
    • (2000) J. Biol. Chem. , vol.275 , pp. 4351
    • Angelo, R.G.1    Rubin, C.S.2
  • 41
    • 0023113876 scopus 로고
    • Characterization of two mutants of the LLC-PK1 porcine kidney cell line affected in the catalytic subunit of the cAMP-dependent protein kinase
    • Botterell S.H., Jans D.A., and Hemmings B.A. Characterization of two mutants of the LLC-PK1 porcine kidney cell line affected in the catalytic subunit of the cAMP-dependent protein kinase. Eur. J. Biochem. 164 (1987) 39
    • (1987) Eur. J. Biochem. , vol.164 , pp. 39
    • Botterell, S.H.1    Jans, D.A.2    Hemmings, B.A.3


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