Microglia and astroglia prevent oxidative stress-induced neuronal cell death: Implications for aceruloplasminemia

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1782, Issue 2, 2008, Pages 109-117

  Oshiro, Satoru ^a   Kawamura, Ken ichi ^b   Zhang, Chun ^a   Sone, Toshio ^c   Morioka, Masaki S ^d   Kobayashi, Shin ^e   Nakajima, Kazuyuki ^f  

^a Faculty of Sports and Health Sciences   (Japan)

^b Department of Research and Development   (Japan)

^c SAITAMA MEDICAL UNIVERSITY   (Japan)

^d TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^e KIRIN BREWERY CO LTD   (Japan)

^f SOKA UNIVERSITY   (Japan)

Author keywords

Aceruloplasminemia; Astrocyte; Microglial; Neurodegenerative disorders; Neuronal cell death; Oxidative stress

Indexed keywords

CERULOPLASMIN; FERRIC CITRATE; HYDROGEN PEROXIDE; IRON;

ACERULOPLASMINEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASTROCYTE; CELL DEATH; CELL PROLIFERATION; CELL VIABILITY; COCULTURE; CONTROLLED STUDY; DEGENERATIVE DISEASE; EMBRYO; GLIA CELL; IRON METABOLISM; MACROGLIA; MICROGLIA; NERVE CELL; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; CELL DEATH; CELLS, CULTURED; CERULOPLASMIN; COCULTURE TECHNIQUES; CYTOPROTECTION; EMBRYO, MAMMALIAN; IRON; MICROGLIA; NERVE DEGENERATION; NEURODEGENERATIVE DISEASES; NEURONS; OXIDATIVE STRESS; RATS;

EID: 39149094622     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2007.12.002     Document Type: Article

References (54)

1. Behl C., Davis J.B., Lesley R., and Schubert D. Hydrogen peroxide mediates amyloidβprotein toxicity. Cell 77 (1994) 817-827
2. Cai Y., Zhang C., Nawa T., Aso T., Tanaka M., Oshiro S., Ichijyo H., and Kitajima S. Homocysteine-responsive ATF3 gene expression in human vascular endothelial cells: activation of c-Jun NH(2)-terminal kinase and promoter response element. Blood 96 (2000) 2140-2148
3. Coyle J.T., and Puttfarcken P. Oxidative stress, glutamate, and neurodegenerative disorders. Science 262 (1993) 689-695
4. Connor J.R., Snyder B.S., Beard J.L., Fine R.E., and Mufson E.J. Regional distribution of iron and iron-regulatory proteins in the brain in aging and Alzheimer's disease. J. Neurosci. Res. 31 (1992) 327-335
5. Donovan A., Brownlie A., Zhou Y., Shepard J., Pratt S.J., Movnihan J., Paw B.H., Drejer A., Barut B., Zapata A., Law T.C., Bruqnara C., Lux S.E., Pinkus G.S., Pinkus J.L., Kingslev P.D., Palis J., Fleming M.D., Andrew N.C., and Zon L.I. Positional cloning of zebrafish ferroportin 1 identifies a conserved vertebrate iron exporter. Nature 403 (2000) 776-781
6. Evans C.A.W., Harbuz M.S., Ostenfeld T., Norrish A., and Blackwell J.M. Nramp1 is expressed in neurons and is associated with behavioural and immune response to stress. Neurogenet. 27 (2001) 69-78
7. Gerlach M., Shachar D.B., Riederer P., and Youdim M.B. Altered brain metabolism of iron as a cause of neurodegenerative diseases?. J. Neurochem. 63 (1994) 793-807 (Review)
8. Good P.F., Perl D.P., Bierer L.M., and Schmeider J. Selective accumulation and iron in the neurofibrillary tangles of Alzheimer's disease: a laser microprobe (LAMMA) study. Ann. Neurol. 31 (1992) 286-292
9. Gunshin H., Mackenzie B., Berger U.V., Gunshin Y., Romero M.F., Borton W.F., Nussberger S., Gollan J.L., and Hediger M.A. Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature 388 (1997) 482-488
10. Halliday W. The nosology of Hallervorden-Spatz disease. J. Neurol. Sci. 134 (1995) 84-91 (suppl.)
11. Halliwell B. Reactive oxygen species and central nervous system. J. Neurochem. 59 (1992) 1609-1623
12. Halliwell B., and Gutteridge J.M.C. Free Radicals in Biology and Medicine (1989), Oxford University Press, Oxford 188-266
13. Harris Z.L., Takahashi Y., Miyajima H., Serizawa M., MacGillivray R.T., and Gitlin J.D. Aceruloplasminemia: molecular characterization of this disorder of iron metabolism. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 2539-2543
14. Harris Z.L., Klomp L.W.J., and Gitlin J.D. Aceruloplasminemia: an inherited neurodegenerative disease with impairment of iron homeostasis. Am. J. Clin. Nut. 67 (1998) 972s-977s (suppl)
15. Hirsch E.C., Brandel J.P., Galle P., Javoy-Agid F., and Agid Y. Iron and aluminum increase in substantia nigra of patients with Parkinson's disease: an X-ray microanalysis. J.Neurochem. 56 (1991) 446-451
16. Kaneko K., Yoshida K., Arima K., Ohara S., Miyajima H., Kato T., Ohta M., and Ikeda S. Astrocytic deformity and globular structures are characteristic of the brains of patients with aceruloplasminemia. J. Neuropathol. Exp. Neurol. 61 (2002) 1069-1077
17. Kaneko K., Nakamura A., Yoshida K., Kametani F., Higuchi K., and Ikeda S. Glial fibrillary acidic protein is greatly modified by oxidative stress in aceruloplasminemia brain. Free Radic Res. 36 (2002) 303-306
18. Kaplan J., Jordan I., and Sturrock A. Regulation of the transferrin-independent iron transport system in cultured cells. J. Biol. Chem. 266 (1992) 2997-3004
19. Kasarskis E.J., Tandon L., Lovell M.A., and Ehmann W.D. Aluminum, calcium, and iron in the spinal cord of patients with sporadic amyotrophic lateral sclerosis using laser microprobe mass spectroscopy: a preliminary study. J. Neurol. Sci. 130 (1995) 203-208
20. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
21. Lim J.H., Wen T.C., Matsuda S., Tanaka J., Meda N., Peng H., Aburaya J., Ishihara K., and Sakanaka M. Protection of ischemic hippocampal neurons by ginsenoside Rb1, a main ingredient of ginseng root. Neurosci. Res. 28 (1997) 191-200
22. Makar T.K., Nedergaad M., Preuss A., Gelbard A.S., Perumal A.S., and Cooper A.J.L. Vitamin E, ascorbate, glutathione, glutathione disulfide, and enzymes of glutathione metabolism in cultures of chick astrocytes and neurons: evidence that astrocytes play an important role in antioxidative processes in the brain. J. Neurochem. 62 (1994) 45-53
23. Maines M.D. The heme oxygenase system: a regulator of second messenger gases. Annu. Rev. Pharmacol. Toxicol. 37 (1997) 517-554
24. Mancuso C., Perluigi M., Cini C., Marco C.D., Maria A., Stella G., and Calabrese V. Heme oxygenase and cyclooxygenase in the central nervous system: a functional interplay. J. Neurosci. Res. 84 (2006) 1385-1391
25. Miyajima H., Nishimura Y., Mizoguchi K., Sakamoto M., Shimizu T., and Honda N. Familial apoceruloplasmin deficiency associated with blepharospasm and retinal degeneration. Neurology 37 (1987) 761-767
26. Miyajima H., Kono S., Takahashi Y., Sugimoto M., Sakamoto M., and Sakai N. Cerebellar ataxia associated with heteroallelic ceruloplasmin gene mutation. Neurology 57 (2001) 2205-2210
27. Morita H., Ikeda S., Yamamoto K., Morita S., Yoshida K., Nomoto S., Kato M., and Yanagisawa N. Hereditary ceruloplasmin deficiency with hemosiderosis: a clinicopathological study of a Japanese family. Ann. Neurol. 37 (1995) 646-656
28. Moos T. Brain iron homeostasis. Dan. Med. Bull. 49 (2002) 279-301
29. Moos T., and Morgan E.H. The significance of the mutated divalent metal transporter (DMT1) on iron transport into the Belgrade rat brain. J. Neurochem. 88 (2004) 233-245
30. Nakajima K., Nakajima M., Hamanoue M., Shimojo M., Takei N., and Kohsaka S. Characterization of microglia isolated from a primary culture of embryonic rat brain by a simplified method. Biomed. Res. 10 (1989) 411-423
31. Nakajima K., Shimojo M., Hamanoue M., Ishiura S., Sugita H., and Kohsaka S. Identification of elastase as a secretory protease from cultured rat microglia. J. Neurochem. 58 (1992) 1401-1408
32. Nakajima K., Honda S., Tohyama Y., Imai Y., Kohsaka S., and Kurihara T. Neurotrophin secretion from cultured microglia. J. Neurosci. Res. 65 (2001)
33. Nakajima K., Tohyama Y., Kohsaka S., and Kurihara T. Ability of rat microglia to uptake extracellular glutamate. Neurosci. Lett. 307 (2001) 171-174
34. Oba H., Araki T., Ohtomo K., Monzawa S., Uchiyama G., Koizumi K., Nogata Y., Kachi K., Shiozawa Z., and Kobayashi M. Amyotrophic lateral sclerosis: T2 shortening in motor cortex at MR imaging. Radiology 189 (1993) 843-846
35. Oshiro S., Kawahara M., Kuroda Y., Zhang C., Cai Y., Kitajima S., and Shirao M. Glial cells contribute more to iron and aluminum accumulation but are more resistant to oxidative stress than neuronal cells. Biochim. Biophys. Acta 1502 (2000) 405-414
36. Oshiro S., Nakajima H., Markello T., Krasnewich D., Bernardini I., and Gahl W. Redox, transferrin-independent and receptor-mediated endocytosis iron uptake system in cultured human fibroblasts. J. Biol. Chem. 268 (1993) 21586-21591
37. Palmer A.M., and Burns M.A. Selective increase in lipid peroxidation in the inferior temporal cortex in Alzheimer's disease. Brain Res. 645 (1994) 338-342
38. Peng H., Wen T.C., Tanaka J., Matsuda S., Desaki J., Sudo S., Zhang B., and Sakanaka M. Epidermal growth factor protects neuronal cells in vivo and in vitro against transient forebrain ischemia- and free radical-induced injuries. J. Cereb. Blood Flow Metab. 18 (1998) 349-360
39. Perl D.P., and Good P.F. Comparative techniques for determining cellular iron distribution in brain tissues. Ann. Neurol. 32 (1992) S76-S81 (Suppl)
40. Piani D., Spranger M., Frei K., Schaffner A., and Fontana A. Macrophage-induced cytotoxicity of N-methyl-d-aspartate receptor positive neurons involves excitatory amino acids rather than reactive oxygen intermediates and cytokines. Eur. J. Immunol. 22 (1992) 2429-2436
41. Polazzi E., Gianni T., and Contestabile A. Microglial cells protect cerebellar granule neurons from apoptosis: evidence for reciprocal signaling. Glia 36 (2001) 271-280
42. Poss K.D., and Tonegawa S. Heme oxygenase 1 is required for mammalian iron reutilization. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 10919-10924
43. Poss K.D., and Tonegawa S. Reduced stress defense in heme oxygenase 1-deficient cells. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 10925-10930
44. Qian Z.M., and Wang Q. Expression of iron transport proteins and excessive iron accumulation in the brain in neurodegenerative disorders. Brain Res. Rev. 27 (1998) 257-267
45. Roeser H.P., Lee G.R., Nacht S., and Cartwright G.E. The role of ceruloplasmin in iron metabolism. J. Clin. Invest. 49 (1970) 2408-2417
46. Roth J.A., Horbinski C., Feng L., Dolan K.G., Higgins D., and Garrick M.D. Differential localization of divalent metal transporter 1 with and without iron response element in rat PC12 and sympathetic neuronal cells. J. Neurosci. 20 (2000) 7595-7601
47. Shimojo M., Imai Y., Nakajima K., Mizushima S., Uemura A., and Kohsaka S. Interleukin-2 enhances the viability of primary cultured rat neocortical neurons. Neurosci. Lett. 151 (1993) 170-173
48. Sofic E., Paulus W., Jellinger K., Riederer P.M., and Yodium M.B.H. Selective increase of iron in substantia nigra zona compacta of Parkinsonian brains. J. Neurochem. 56 (1991) 978-982
49. Song N., Jiang H., and Xie J.X. Divalent metal transporter 1 upregulation is involved in the 6-hydroxydopamine-induced ferrous iron influx. J. Neurosci. Res. (2007) Jul 30 [Electronic publication ahead of print]
50. Sturrock A., Alexander J., and Lamb J. Characterization of a transferrin-independent uptake system for iron in HeLa cells. J. Biol. Chem 265 (1990) 3139-3145
51. Takeda A., Devenyi A., and Connor J.R. Evidence for non-transferrin-mediated uptake and release of iron and manganese in glial cell cultures from hypotransferrinemic mice. J. Neurosci. Res. 51 (1998) 454-462
52. Tanaka J., Toku K., Zahng B., Ishihara K., Sakanaka M., and Maeda N. Astrocytes prevent neuronal death induced by reactive oxygen and nitrogen species. Glia 28 (1999) 85-96
53. Toku K., Tanaka J., Yano H., Desaki J., Zhang B., Yang L., Ishihara K., Sakanaka M., and Maeda N. Microglial cells prevent nitric oxide-induced neuronal apoptosis in vitro. J. Neurosci. Res. 53 (1998) 415-425
54. Yoshida K., Furihata K., Takeda S., Nakamura A., Yamamoto K., Morita H., Hiyamuta S., Ikeda S., Shimizu N., and Yanagisawa N. A mutation in the ceruloplasmin gene is associated with systemic hemosiderosis in humans. Nat. Genet. 9 (1995) 267-272