메뉴 건너뛰기




Volumn 274, Issue , 2006, Pages 118-126

Role of Akt in cardiac growth and metabolism

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SOMATOMEDIN C;

EID: 39049192580     PISSN: 15282511     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper
Times cited : (28)

References (31)
  • 1
    • 0035368548 scopus 로고    scopus 로고
    • Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)
    • Cho H, Mu J, Kim JK et al 2001a Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta). Science 292:1728-1731
    • (2001) Science , vol.292 , pp. 1728-1731
    • Cho, H.1    Mu, J.2    Kim, J.K.3
  • 2
    • 0035914388 scopus 로고    scopus 로고
    • Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice
    • Cho H, Thorvaldsen JL, Chu Q, Feng F, Birnbaum MJ 2001b Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice. J Biol Chem 276:38349-38352
    • (2001) J Biol Chem , vol.276 , pp. 38349-38352
    • Cho, H.1    Thorvaldsen, J.L.2    Chu, Q.3    Feng, F.4    Birnbaum, M.J.5
  • 3
    • 0037125980 scopus 로고    scopus 로고
    • Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice
    • Condorelli G, Drusco A, Stassi G et al 2002 Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice. Proc Natl Acad Sci USA 99:12333-12338
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 12333-12338
    • Condorelli, G.1    Drusco, A.2    Stassi, G.3
  • 4
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: A play in three Akts
    • Datta SR, Brunet A, Greenberg ME 1999 Cellular survival: a play in three Akts. Genes Dev 13:2905-2927
    • (1999) Genes Dev , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 5
    • 33646449520 scopus 로고    scopus 로고
    • Akt1 is required for physiological cardiac growth
    • DeBosch B, Treskov I, Lupu TS et al 2006 Akt1 is required for physiological cardiac growth. Circulation 113:2097-2104
    • (2006) Circulation , vol.113 , pp. 2097-2104
    • DeBosch, B.1    Treskov, I.2    Lupu, T.S.3
  • 6
    • 0037369166 scopus 로고    scopus 로고
    • Microarray expression analysis of effects of exercise training: Increase in atrial MLC-1 in rat ventricles
    • Diffee GM, Seversen EA, Stein TD, Johnson JA 2003 Microarray expression analysis of effects of exercise training: increase in atrial MLC-1 in rat ventricles. Am J Physiol Heart Circ Physiol 284:H830-837
    • (2003) Am J Physiol Heart Circ Physiol , vol.284
    • Diffee, G.M.1    Seversen, E.A.2    Stein, T.D.3    Johnson, J.A.4
  • 7
    • 0034730790 scopus 로고    scopus 로고
    • Early activation of the multicomponent signaling complex associated with focal adhesion kinase induced by pressure overload in the rat heart
    • Franchini KG, Torsoni AS, Soares PH, Saad MJ 2000 Early activation of the multicomponent signaling complex associated with focal adhesion kinase induced by pressure overload in the rat heart. Circ Res 87:558-565
    • (2000) Circ Res , vol.87 , pp. 558-565
    • Franchini, K.G.1    Torsoni, A.S.2    Soares, P.H.3    Saad, M.J.4
  • 8
    • 85047693348 scopus 로고    scopus 로고
    • Severe diabetes, age-dependent loss of adipose tissue and mild growth deficiency in mice lacking Akt2/PKB?
    • Garofalo RS, Orena SJ, Rafidi K et al 2003 Severe diabetes, age-dependent loss of adipose tissue and mild growth deficiency in mice lacking Akt2/PKB?. J Clin Invest 112:197-208
    • (2003) J Clin Invest , vol.112 , pp. 197-208
    • Garofalo, R.S.1    Orena, S.J.2    Rafidi, K.3
  • 9
    • 2542528670 scopus 로고    scopus 로고
    • A family with severe insulin resistance and diabetes due to a mutation in AKT2
    • George S, Rochford JJ, Wolfrum C et al 2004 A family with severe insulin resistance and diabetes due to a mutation in AKT2. Science 304:1325-1328
    • (2004) Science , vol.304 , pp. 1325-1328
    • George, S.1    Rochford, J.J.2    Wolfrum, C.3
  • 10
    • 0032520009 scopus 로고    scopus 로고
    • 4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway
    • Gingras AC, Kennedy SG, O'Leary MA, Sonenberg N, Hay N 1998 4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway. Genes Dev 12:502-513
    • (1998) Genes Dev , vol.12 , pp. 502-513
    • Gingras, A.C.1    Kennedy, S.G.2    O'Leary, M.A.3    Sonenberg, N.4    Hay, N.5
  • 11
    • 0035312747 scopus 로고    scopus 로고
    • Regulation of translation initiation by FRAP/mTOR
    • Gingras AC, Rought B, Sonenberg N 2001 Regulation of translation initiation by FRAP/mTOR. Genes Dev 15:807-826
    • (2001) Genes Dev , vol.15 , pp. 807-826
    • Gingras, A.C.1    Rought, B.2    Sonenberg, N.3
  • 12
    • 0034282892 scopus 로고    scopus 로고
    • Negative regulation of the serine/threonine kinase B-Raf by Akt
    • Guan KL, Figueroa C, Brtva TR et al 2000 Negative regulation of the serine/threonine kinase B-Raf by Akt. J Biol Chem 275:27354-27359
    • (2000) J Biol Chem , vol.275 , pp. 27354-27359
    • Guan, K.L.1    Figueroa, C.2    Brtva, T.R.3
  • 13
    • 0035133227 scopus 로고    scopus 로고
    • Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1
    • Kim AH, Khursigara G, Sun X, Franke TF, Chao MV 2001 Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1. Mol Cell Biol 21:893-901
    • (2001) Mol Cell Biol , vol.21 , pp. 893-901
    • Kim, A.H.1    Khursigara, G.2    Sun, X.3    Franke, T.F.4    Chao, M.V.5
  • 14
    • 0034845958 scopus 로고    scopus 로고
    • PKB/Akt: A key mediator of cell proliferation, survival and insulin responses?
    • Lawlor MA, Alessi DR 2001 PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? J Cell Sci 114:2903-2910
    • (2001) J Cell Sci , vol.114 , pp. 2903-2910
    • Lawlor, M.A.1    Alessi, D.R.2
  • 15
    • 0037151104 scopus 로고    scopus 로고
    • Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart
    • Matsui T, Li L, Wu JC et al 2002 Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart. J Biol Chem 277:22896-22901
    • (2002) J Biol Chem , vol.277 , pp. 22896-22901
    • Matsui, T.1    Li, L.2    Wu, J.C.3
  • 16
    • 0142027759 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase(p110alpha) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy
    • McMullen JR, Shioi T, Zhang L et al 2003 Phosphoinositide 3-kinase(p110alpha) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy. Proc Natl Acad Sci USA 100:12355-12360
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 12355-12360
    • McMullen, J.R.1    Shioi, T.2    Zhang, L.3
  • 17
    • 0033834163 scopus 로고    scopus 로고
    • Early sequence of cardiac adaptations and growth factor formation in pressure- and volume-overload hypertrophy
    • Modesti PA, Vanni S, Bertolozzi I et al 2000 Early sequence of cardiac adaptations and growth factor formation in pressure- and volume-overload hypertrophy. Am J Physiol Heart Circ Physiol 279:H976-985
    • (2000) Am J Physiol Heart Circ Physiol , vol.279
    • Modesti, P.A.1    Vanni, S.2    Bertolozzi, I.3
  • 18
    • 0032540252 scopus 로고    scopus 로고
    • Activation of phosphatidylinositol 3-kinase through glycoprotein 130 induces protein kinase B and p70 S6 kinase phosphorylation in cardiac myocytes
    • Oh H, Fujio Y, Kunisada K et al 1998 Activation of phosphatidylinositol 3-kinase through glycoprotein 130 induces protein kinase B and p70 S6 kinase phosphorylation in cardiac myocytes. J Biol Chem 273:9703-9710
    • (1998) J Biol Chem , vol.273 , pp. 9703-9710
    • Oh, H.1    Fujio, Y.2    Kunisada, K.3
  • 19
    • 0037169526 scopus 로고    scopus 로고
    • Akt (protein kinase B) negatively regulates SEK1 by means of protein phosphorylation
    • Park HS, Kim MS, Huh SH et al 2002 Akt (protein kinase B) negatively regulates SEK1 by means of protein phosphorylation. J Biol Chem 277:2573-2578
    • (2002) J Biol Chem , vol.277 , pp. 2573-2578
    • Park, H.S.1    Kim, M.S.2    Huh, S.H.3
  • 20
    • 0038624395 scopus 로고    scopus 로고
    • Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2
    • Peng XD, Xu PZ, Chen ML et al 2003 Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2. Genes Dev 17:1352-1365
    • (2003) Genes Dev , vol.17 , pp. 1352-1365
    • Peng, X.D.1    Xu, P.Z.2    Chen, M.L.3
  • 21
    • 0035823542 scopus 로고    scopus 로고
    • Regulation of Raf by Akt controls growth and differentiation in vascular smooth muscle cells
    • Reusch HP, Zimmermann S, Schaefer M, Paul M, Moelling K 2001 Regulation of Raf by Akt controls growth and differentiation in vascular smooth muscle cells. J Biol Chem 276:33630-33637
    • (2001) J Biol Chem , vol.276 , pp. 33630-33637
    • Reusch, H.P.1    Zimmermann, S.2    Schaefer, M.3    Paul, M.4    Moelling, K.5
  • 22
    • 0030969371 scopus 로고    scopus 로고
    • The cellular and molecular response of cardiac myocytes to mechanical stress
    • Sadoshima J, Izumo S 1997 The cellular and molecular response of cardiac myocytes to mechanical stress. Annu Rev Physiol 59:551-571
    • (1997) Annu Rev Physiol , vol.59 , pp. 551-571
    • Sadoshima, J.1    Izumo, S.2
  • 23
    • 0037292011 scopus 로고    scopus 로고
    • Short- and long-term swimming exercise training increases myocardial insulin-like growth factor-I gene expression
    • Scheinowitz M, Kessler-Icekson G, Freimann S et al 2003 Short- and long-term swimming exercise training increases myocardial insulin-like growth factor-I gene expression. Growth Horm IGF Res 13:19-25
    • (2003) Growth Horm IGF Res , vol.13 , pp. 19-25
    • Scheinowitz, M.1    Kessler-Icekson, G.2    Freimann, S.3
  • 24
    • 0034213075 scopus 로고    scopus 로고
    • The conserved phosphoinositide 3-kinase pathway determines heart size in mice
    • Shioi T, Kang PM, Douglas PS et al 2000 The conserved phosphoinositide 3-kinase pathway determines heart size in mice. EMBO J 19:2537-2548
    • (2000) EMBO J , vol.19 , pp. 2537-2548
    • Shioi, T.1    Kang, P.M.2    Douglas, P.S.3
  • 25
    • 0036200937 scopus 로고    scopus 로고
    • Akt/protein kinase B promotes organ growth in transgenic mice
    • Shioi T, McMullen JR, Kang PM et al 2002 Akt/protein kinase B promotes organ growth in transgenic mice. Mol Cell Biol 22:2799-2809
    • (2002) Mol Cell Biol , vol.22 , pp. 2799-2809
    • Shioi, T.1    McMullen, J.R.2    Kang, P.M.3
  • 26
    • 0036550053 scopus 로고    scopus 로고
    • 3′-phosphoinositide-dependent kinase-1 (PDK-1) in PI 3-kinase signaling
    • Storz P, Toker A 2002 3′-phosphoinositide-dependent kinase-1 (PDK-1) in PI 3-kinase signaling. Front Biosci 7:886-902
    • (2002) Front Biosci , vol.7 , pp. 886-902
    • Storz, P.1    Toker, A.2
  • 27
    • 0034911881 scopus 로고    scopus 로고
    • Synthesis and function of 3-phosphorylated inositol lipids
    • Vanhaesebroeck B, Leevers SJ, Ahmadi K et al 2001 Synthesis and function of 3-phosphorylated inositol lipids. Annu Rev Biochem 70:535-602
    • (2001) Annu Rev Biochem , vol.70 , pp. 535-602
    • Vanhaesebroeck, B.1    Leevers, S.J.2    Ahmadi, K.3
  • 28
    • 0032557646 scopus 로고    scopus 로고
    • Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB
    • van Weeren PC, de Bruyn KM, de Vries-Smits AM, van Lint J, Burgering BM 1998 Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB. J Biol Chem 273:13150-13156
    • (1998) J Biol Chem , vol.273 , pp. 13150-13156
    • van Weeren, P.C.1    de Bruyn, K.M.2    de Vries-Smits, A.M.3    van Lint, J.4    Burgering, B.M.5
  • 29
    • 0347320747 scopus 로고    scopus 로고
    • Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy
    • Wilkins BJ, Dai YS, Bueno OF et al 2004 Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy. Circ Res 94:110-118
    • (2004) Circ Res , vol.94 , pp. 110-118
    • Wilkins, B.J.1    Dai, Y.S.2    Bueno, O.F.3
  • 30
    • 0035072833 scopus 로고    scopus 로고
    • A motif-based profile scanning approach for genome-wide prediction of signaling pathways
    • Yaffe MB, Leparc GG, Lai J, Obata T, Volinia S, Cantley LC 2001 A motif-based profile scanning approach for genome-wide prediction of signaling pathways. Nat Biotechnol 19:348-353
    • (2001) Nat Biotechnol , vol.19 , pp. 348-353
    • Yaffe, M.B.1    Leparc, G.G.2    Lai, J.3    Obata, T.4    Volinia, S.5    Cantley, L.C.6
  • 31
    • 15444374951 scopus 로고    scopus 로고
    • Akt2 phosphorylates Synip to regulate docking and fusion of GLUT4-containing vesicles
    • Yamada E, Okada S, Saito T et al 2005 Akt2 phosphorylates Synip to regulate docking and fusion of GLUT4-containing vesicles. J Cell Biol 168:921-928
    • (2005) J Cell Biol , vol.168 , pp. 921-928
    • Yamada, E.1    Okada, S.2    Saito, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.