Reduction of iatrogenic RPE lesions in AMD patients: Evidence for wound healing?

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 246, Issue 3, 2008, Pages 345-352

  Rabenlehner, Doris ^a,b   Stanzel, Boris V ^a,c   Krebs, Ilse ^a,b   Binder, Susanne ^a,b   Goll, Alexandra ^d  

^a LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

^b KRANKENANSTALT RUDOLFSTIFTUNG   (Austria)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Age related macular degeneration; Fundus autofluorescence; Retinal pigment epithelium; Wound healing

Indexed keywords

ADULT; AGED; ARTICLE; AUTOFLUORESCENCE; AUTOTRANSPLANTATION; CLINICAL ARTICLE; COMPUTER PROGRAM; CONTROLLED STUDY; FEMALE; FLUORESCENCE ANGIOGRAPHY; HUMAN; IATROGENIC DISEASE; MALE; PIGMENT EPITHELIUM; POSTOPERATIVE CARE; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; SUBRETINAL NEOVASCULARIZATION; TREATMENT DURATION; VITRECTOMY; WOUND HEALING;

AGED; AGED, 80 AND OVER; CHOROIDAL NEOVASCULARIZATION; DEBRIDEMENT; FEMALE; FLUORESCEIN ANGIOGRAPHY; HUMANS; IATROGENIC DISEASE; MACULAR DEGENERATION; MALE; MIDDLE AGED; PIGMENT EPITHELIUM OF EYE; VITRECTOMY; WOUND HEALING;

EID: 39049171205     PISSN: 0721832X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00417-007-0658-6     Document Type: Article

References (48)

1. Zhao S, Rizzolo LJ, Barnstable CJ (1997) Differentiation and transdifferentiation of the retinal pigment epithelium. Int Rev Cyt 171:225-266
2. Coulombre AJ (1979) Roles of the retinal pigment epithelium in the development of ocular tissues. In: Zinn KM, Marmor MF (eds) The retinal pigment epithelium. Harvard University Press, Cambridge, MA, pp 267-276
3. Grierson I, Hiscott P, Hogg P et al (1994) Development, repair and regeneration of the retinal pigment epithelium. Eye 8(Pt 2):255-262
4. Harman AM, Fleming PA, Hoskins RV, Moore SR (1997) Development and aging of cell topography in the human retinal pigment epithelium. Invest Ophthalmol Vis Sci 38:2016-2026
5. Panda-Jonas S, Jonas JB, Jakobczyk-Zmija M (1996) Retinal pigment epithelial cell count, distribution, and correlations in normal human eyes. Am J Ophthalmol 121:181-189
6. Del Priore LV, Kuo YH, Tezel TH (2002) Age-related changes in human RPE cell density and apoptosis proportion in situ. Invest Ophthalmol Vis Sci 43:3312-3318
7. Korte GE, Reppucci V, Henkind P (1984) RPE destruction causes choriocapillary atrophy. Invest Ophthalmol Vis Sci 25:1135-1145
8. Lopez PF, Yan Q, Kohen L et al (1995) Retinal pigment epithelial wound healing in vivo. Arch Ophthalmol 113:1437-1446
9. Valentino TL, Kaplan HJ, Del Priore LV et al (1995) Retinal pigment epithelial repopulation in monkeys after submacular surgery. Arch Ophthalmol 113:932-938
10. Leonard DS, Zhang XG, Panozzo G, Sugino IK, Zarbin MA (1997) Clinicopathologic correlation of localized retinal pigment epithelium debridement. Invest Ophthalmol Vis Sci 38:1094-1109
11. Marmor MF (1998) Structure, function, and disease of the retinal pigment epithelium. In: Marmor MF, Wolfensberger TJ (eds) The retinal pigment epithelium: Function and disease. Oxford University Press, New York, Oxford, pp 3-12
12. Strauss O (2005) The retinal pigment epithelium in visual function. Physiol Rev 85:845-881
13. Korte GE, Perlman JI, Pollack A (1994) Regeneration of mammalian retinal pigment epithelium. Int Rev Cytol 152:223-263
14. Del Priore LV, Hornbeck R, Kaplan HJ et al (1995) Debridement of the pig retinal pigment epithelium in vivo. Arch Ophthalmol 113:939-944
15. Klein R, Klein BE, Linton KL (1992) Prevalence of age-related maculopathy. The Beaver Dam Eye Study. Ophthalmology 99:933-943
16. Zarbin MA (2004) Current concepts in the pathogenesis of age-related macular degeneration. Arch Ophthalmol 122:598-614
17. Ferris FL, III, Fine SL, Hyman L (1984) Age-related macular degeneration and blindness due to neovascular maculopathy. Arch Ophthalmol 102:1640-1642
18. Pollack JS, Del Priore LV, Smith ME, Feiner MA, Kaplan HJ (1996) Postoperative abnormalities of the choriocapillaris in exudative age-related macular degeneration. Br J Ophthalmol 80:314-318
19. Nasir MA, Sugino I, Zarbin MA (1997) Decreased choriocapillaris perfusion following surgical excision of choroidal neovascular membranes in age-related macular degeneration. Br J Ophthalmol 81:481-489
20. Del Priore LV, Kaplan HJ, Hornbeck R, Jones Z, Swinn M (1996) Retinal pigment epithelial debridement as a model for the pathogenesis and treatment of macular degeneration. Am J Ophthalmol 122:629-643
21. Wang H, Ninomiya Y, Sugino IK, Zarbin MA (2003) Retinal pigment epithelium wound healing in human Bruch's membrane explants. Invest Ophthalmol Vis Sci 44:2199-2210
22. Tezel TH, Kaplan HJ, Del Priore LV (1999) Fate of human retinal pigment epithelial cells seeded onto layers of human Bruch's membrane. Invest Ophthalmol Vis Sci 40:467-476
23. Gullapalli VK, Sugino IK, Van Patten Y, Shah S, Zarbin MA (2005) Impaired RPE survival on aged submacular human Bruch's membrane. Exp Eye Res 80:235-248
24. Liu X, Ye X, Yanoff M, Li W (1997) Extracellular matrix of retinal pigment epithelium regulates choriocapillaris endothelial survival in vitro. Exp Eye Res 65:117-126
25. Leonard DS, Sugino IK, Zhang XG et al (2003) Ultrastructural analysis of hydraulic and abrasive retinal pigment epithelial cell debridements. Exp Eye Res 76:473-491
26. Sawa M, Kamei M, Ohji M et al (2002) Changes in fluorescein angiogram early after surgical removal of choroidal neovascularization in age-related macular degeneration. Graefe Arch Clin Exp Ophthalmol 240:12-16
27. van Meurs JC, ter Averst E, Croxen R, Hofland L, van Hagen PM (2004) Comparison of the growth potential of retinal pigment epithelial cells obtained during vitrectomy in patients with age-related macular degeneration or complex retinal detachment. Graefe's Arch Clin Exp Ophthalmol 242:442-443
28. Del Priore LV, Kaplan HJ, Tezel TH et al (2001) Retinal pigment epithelial cell transplantation after subfoveal membranectomy in age-related macular degeneration: Clinicopathologic correlation. Am J Ophthalmol 131:472-480
29. Binder S, Krebs I, Hilgers RD et al (2004) Outcome of transplantation of autologous retinal pigment epithelium in age-related macular degeneration: A prospective trial. Invest Ophthalmol Vis Sci 45:4151-4160
30. Binder S, Stolba U, Krebs I et al (2002) Transplantation of autologous retinal pigment epithelium in eyes with foveal neovascularization resulting from age-related macular degeneration: A pilot study. Am J Ophthalmol 133:215-225
31. van Meurs JC, ter Averst E, Hofland LJ et al (2004) Autologous peripheral retinal pigment epithelium translocation in patients with subfoveal neovascular membranes. Br J Ophthalmol 88:110-113
32. Phillips SJ, Sadda SR, Tso MO et al (2003) Autologous transplantation of retinal pigment epithelium after mechanical debridement of Bruch's membrane. Curr Eye Res 26:81-88
33. von Ruckmann A, Fitzke FW, Bird AC (1997) Fundus autofluorescence in age-related macular disease imaged with a laser scanning ophthalmoscope. Invest Ophthalmol Vis Sci 38:478-486
34. Okubo A, Rosa RH, Jr., Bunce CV et al (1999) The relationships of age changes in retinal pigment epithelium and Bruch's membrane. Invest Ophthalmol Vis Sci 40:443-449
35. Tezel TH, Del Priore LV, Kaplan HJ (2004) Reengineering of aged Bruch's membrane to enhance retinal pigment epithelium repopulation. Invest Ophthalmol Vis Sci 45:3337-3348
36. Boulton M, Dayhaw Barker P (2001) The role of the retinal pigment epithelium: Topographical variation and ageing changes. Eye 15:384-389
37. Boulton M, Roanowska M, Wess T (2004) Ageing of the retinal pigment epithelium: Implications for transplantation. Graefe's Arch Clin Exp Ophthalmol 242:76-84
38. Zarbin MA (2003) Analysis of retinal pigment epithelium integrin expression and adhesion to aged submacular human Bruch's membrane. Trans Am Ophthalmol Soc 101:499-520
39. Tso MO (1997) Developmental, reactive and neoplastic proliferation of the retinal pigment epithelium. In: Zinn KM, Marmor MF (eds) The retinal pigment epithelium. Harvard University Press, Cambridge, pp 267-276
40. Del Monte MA, Maumenee IH (1980) New technique for in vitro culture of human retinal epithelium. Birth Defects Orig Atic Ser 16:327-338
41. Delori FC, Dorey CK, Staurenghi G et al (1995) In vivo fluorescence of the ocular fundus exhibits retinal pigment epithelium lipofuscin characteristics. Invest Ophthalmol Vis Sci 36:718-729
42. Sparrow JR, Boulton M (2005) RPE lipofuscin and its role in retinal pathobiology. Exp Eye Res 80:595-606
43. Delori FC (1994) Spectrophotometer for noninvasive measurement of the intrinsic fluorescence and reflectance of the ocular fundus. Appl Opt 33:7439-7452
44. von Ruckmann A, Fitzke FW, Bird AC (1995) Distribution of fundus autofluorescence with a scanning laser ophthalmoscope. Br J Ophthalmol 79:407-412
45. Schmitz-Valckenberg S, Bultmann S, Dreyhaupt J et al (2004) Fundus autofluorescence and fundus perimetry in the junctional zone of geographic atrophy in patients with age-related macular degeneration. Invest Ophthalmol Vis Sci 45:4470-4476
46. Opas M (1994) Substratum mechanics and cell differentiation. Int Rev Cytol 150:119-137
47. Sarks S (1978). Changes in the region of the choriocapillaris in ageing and degeneration. In: Shimizu K, Oosterhuis J (eds) Concillium ophthalmologicum. Excerpta Medica, Kyoto, pp 228-238
48. Jonas JB, Gusek GC, Naumann GO (1988) Optic disc, cup and neuroretinal rim size, configuration and correlations in normal eyes. Invest Ophthalmol Vis Sci 29:1151-1158