Molecular characterization of BjussuSP-I, a new thrombin-like enzyme with procoagulant and kallikrein-like activity isolated from Bothrops jararacussu snake venom

Biochimie

Volumn 90, Issue 3, 2008, Pages 500-507

  Sant'Ana, Carolina D ^a   Bernardes, Carolina P ^a   Izidoro, Luiz Fernando M ^a   Mazzi, Maurício V ^a   Soares, Sandro G ^a   Fuly, André L ^b   Zingali, Russolina B ^c   Magro, Angelo J ^d   Braz, Antonio S K ^d   Fontes, Marcos R M ^d   Stábeli, Rodrigo G ^e   Sampaio, Suely V ^a   Soares, Andreimar M ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

^c FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^d SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^e UNIVERSIDADE FEDERAL DE RONDÔNIA   (Brazil)

Author keywords

Bothrops jararacussu; cDNA; Glycosylation; Proteolytic activity; Snake venom; Structural characterization; Thrombin like enzyme

Indexed keywords

AMINO ACID; BATROXOBIN; BJUSSUSP 1 TOXIN; KALLIKREIN; SERINE PROTEINASE; THROMBIN; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME STRUCTURE; ENZYME SUBSTRATE; MOLECULAR DYNAMICS; OPEN READING FRAME; PROTEIN DEGRADATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BLOOD COAGULATION FACTORS; BOTHROPS; CLONING, MOLECULAR; CROTALID VENOMS; DNA, COMPLEMENTARY; KALLIKREINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; SERINE ENDOPEPTIDASES; THROMBIN; THROMBIN TIME;

BOTHROPS JARARACUSSU;

EID: 39049168155     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2007.10.005     Document Type: Article

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