Snake venom serine proteinases: Sequence homology vs. substrate specificity, a paradox to be solved

Toxicon

Volumn 45, Issue 8, 2005, Pages 1115-1132

  Serrano, Solange M T ^a   Maroun, Rachid C ^b  

^a INSTITUTO BUTANTAN   (Brazil)

^b INSTITUT PASTEUR   (France)

Author keywords

3D structure activity relationships; Blood clotting; Factor V activation; Kinin release; Molecular modeling; Molecular recognition; Platelet aggregation; Protein C activation; Snake venom serine proteinases

Indexed keywords

SERINE PROTEINASE; SNAKE VENOM;

AMINO ACID SEQUENCE; BIOCHEMISTRY; BIOLOGICAL ACTIVITY; BIOPHYSICS; BLOOD CLOTTING; ENZYME SPECIFICITY; EVOLUTION; FIBRINOLYSIS; HEMOSTASIS; KALLIKREIN KININ SYSTEM; MOLECULAR BIOLOGY; PHYLOGENY; PRIORITY JOURNAL; REVIEW; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; THROMBOCYTE;

EID: 19544394247     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2005.02.020     Document Type: Article

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