A common mechanism for branching, cyclopropanation, and cyclobutanation reactions in the isoprenoid biosynthetic pathway

Journal of the American Chemical Society

Volumn 130, Issue 6, 2008, Pages 1966-1971

  Thulasiram, Hirekodathakallu V ^a,b   Erickson, Hans K ^a,c   Poulter, C Dale ^a  

^a UNIVERSITY OF UTAH   (United States)

^b NATIONAL CHEMICAL LABORATORY   (India)

^c IMMUNOGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAIN ELONGATION; CYCLOPROPANATION; KINETIC ISOTOPE EFFECTS; PLANOCOCCYL DIPHOSPHATE;

BIOSYNTHESIS; DEUTERIUM; ENZYME ACTIVITY; PROTEINS;

REACTION KINETICS;

CARBON; CHIMERIC PROTEIN; CHRYSANTHEMYL DIPHOSPHATE; CHRYSANTHEMYL DIPHOSPHATE SYNTHASE; DEUTERIUM; DIMETHYLALLYL DIPHOSPHATE; GERANYL DIPHOSPHATE; GERANYLTRANSFERASE; HYDROGEN; ISOPRENOID; MACONELLIYL DIPHOSPHATE; METHYL GROUP; PLANOCOCCYL DIPHOSPHATE; PYROPHOSPHORIC ACID DERIVATIVE; SYNTHETASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CATALYST; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; CYCLOBUTANATION REACTION; CYCLOPROPANATION; DIPOLE; ENZYME ACTIVE SITE; REACTION ANALYSIS; STRUCTURE ANALYSIS; SYNTHESIS;

ARTEMISIA; CYCLOBUTANES; CYCLOPROPANES; GERANYLTRANSTRANSFERASE; MOLECULAR CONFORMATION; TERPENES;

EID: 39049120483     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0771282     Document Type: Article

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