메뉴 건너뛰기




Volumn 33, Issue 3, 2008, Pages 401-411

The role of 3-O-methyldopa in the side effects of L-dopa

Author keywords

3 O methyldopa; L dopa; Locomotor activity; Oxidative stress; Parkinson's disease

Indexed keywords

3 O METHYLDOPA; ADENOSINE; ALPHA TOCOPHEROL; CATECHOLAMINE; DOPAMINE; DOPAMINE TRANSPORTER; HOMOCYSTEINE; LEVODOPA;

EID: 38949133757     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-007-9442-6     Document Type: Article
Times cited : (43)

References (49)
  • 1
    • 0015356319 scopus 로고
    • Plasma 3-O-methyldopa in l-dopa therapy of Parkinson's disease
    • Muenter MD, Sharpless NS, Tyce GM (1972) Plasma 3-0-methyldopa in l-dopa therapy of Parkinson's disease. Mayo Clin Proc 47:389-395
    • (1972) Mayo Clin Proc , vol.47 , pp. 389-395
    • Muenter, M.D.1    Sharpless, N.S.2    Tyce, G.M.3
  • 2
    • 0015302499 scopus 로고
    • 3-methoxy-4-hydroxyphenylalanine (3-O-methyldopa) in plasma during oral L-dopa therapy of patients with Parkinson's disease
    • Sharpless NS, Muenter MD, Tyce GM et al (1972) 3-methoxy-4- hydroxyphenylalanine (3-O-methyldopa) in plasma during oral l-dopa therapy of patients with Parkinson's disease. Clin Chim Acta 37:359-369
    • (1972) Clin Chim Acta , vol.37 , pp. 359-369
    • Sharpless, N.S.1    Muenter, M.D.2    Tyce, G.M.3
  • 3
    • 0020685128 scopus 로고
    • Effects of 3-OM-dopa on monoamine metabolism in rat brain
    • Gervas JJ, Muradas V, Bazan E et al (1983) Effects of 3-OM-dopa on monoamine metabolism in rat brain. Neurology 33:278-282
    • (1983) Neurology , vol.33 , pp. 278-282
    • Gervas, J.J.1    Muradas, V.2    Bazan, E.3
  • 4
    • 0025818260 scopus 로고
    • Concentrations of tyrosine, l-dihydroxyphenylalanine, dopamine, and 3-O-methyldopa in the cerebrospinal fluid of Parkinson's disease
    • Tohgi H, Abe T, Takahashi S (1991b) Concentrations of tyrosine, l-dihydroxyphenylalanine, dopamine, and 3-O-methyldopa in the cerebrospinal fluid of Parkinson's disease. Neurosci Lett 127:212-214
    • (1991) Neurosci Lett , vol.127 , pp. 212-214
    • Tohgi, H.1    Abe, T.2    Takahashi, S.3
  • 5
    • 0031018201 scopus 로고    scopus 로고
    • Effect of l-Dopa and the catechol-O-methyltransferase inhibitor Ro 41-0960 on sulfur amino acid metabolites in rats
    • Miller JW, Shukitt-Hale B, Villalobos-Molina R et al (1997) Effect of l-Dopa and the catechol-O-methyltransferase inhibitor Ro 41-0960 on sulfur amino acid metabolites in rats. Clin Neuropharmacol 20:55-66
    • (1997) Clin Neuropharmacol , vol.20 , pp. 55-66
    • Miller, J.W.1    Shukitt-Hale, B.2    Villalobos-Molina, R.3
  • 6
    • 0015089408 scopus 로고
    • The metabolism of l-3-O-methyldopa, a precursor of dopa in man
    • Kuruma I, Bartholini G, Tissot R et al (1971) The metabolism of l-3-O-methyldopa, a precursor of dopa in man. Clin Pharmacol Ther 12:678-82
    • (1971) Clin Pharmacol Ther , vol.12 , pp. 678-82
    • Kuruma, I.1    Bartholini, G.2    Tissot, R.3
  • 7
    • 0022608793 scopus 로고
    • Repeated levodopa infusions in fluctuating Parkinson's disease: Clinical and pharmacokinetic data
    • Marion MH, Stocchi F, Quinn NP et al (1986) Repeated levodopa infusions in fluctuating Parkinson's disease: clinical and pharmacokinetic data. Clin Neuropharmacol 9:165-181
    • (1986) Clin Neuropharmacol , vol.9 , pp. 165-181
    • Marion, M.H.1    Stocchi, F.2    Quinn, N.P.3
  • 8
    • 0027988507 scopus 로고
    • Problems with long-term levodopa therapy for Parkinson's disease
    • Marsden CD (1994) Problems with long-term levodopa therapy for Parkinson's disease. Clin Neuropharmacol Suppl 2:S32-S44
    • (1994) Clin Neuropharmacol Suppl , vol.2
    • Marsden, C.D.1
  • 9
    • 0017603372 scopus 로고
    • Plasma O-methyldopa in levodopa-induced dyskinesias. a bioclinical investigation
    • Feuerstein C, Serre F, Gavend M et al (1977a) Plasma O-methyldopa in levodopa-induced dyskinesias. A bioclinical investigation. Acta Neurol Scand 56:508-524
    • (1977) Acta Neurol Scand , vol.56 , pp. 508-524
    • Feuerstein, C.1    Serre, F.2    Gavend, M.3
  • 10
    • 0017684305 scopus 로고
    • Does O-methyl-dopa play a role in levodopa-induced dyskinesias
    • Feuerstein C, Tauche M, Serre F et al (1977b) Does O-methyl-dopa play a role in levodopa-induced dyskinesias. Acta Neurol Scand 56:79-82
    • (1977) Acta Neurol Scand , vol.56 , pp. 79-82
    • Feuerstein, C.1    Tauche, M.2    Serre, F.3
  • 11
    • 0023255223 scopus 로고
    • Pharmacokinetics of l-dopa in patients with Parkinson's disease
    • Mena MA, Muradas V, Bazan E et al (1987) Pharmacokinetics of l-dopa in patients with Parkinson's disease. Adv Neurol 45:481-486
    • (1987) Adv Neurol , vol.45 , pp. 481-486
    • Mena, M.A.1    Muradas, V.2    Bazan, E.3
  • 12
    • 10744223966 scopus 로고    scopus 로고
    • Modifications of plasma and platelet levels of l-DOPA and its direct metabolites during treatment with tolcapone or entacapone in patients with Parkinson's disease
    • Blandini F, Nappi G, Fancellu R et al (2003) Modifications of plasma and platelet levels of l-DOPA and its direct metabolites during treatment with tolcapone or entacapone in patients with Parkinson's disease. J Neural Transm 110:911-922
    • (2003) J Neural Transm , vol.110 , pp. 911-922
    • Blandini, F.1    Nappi, G.2    Fancellu, R.3
  • 13
    • 0026018261 scopus 로고
    • The significance of 3-O-methyldopa concentrations in the cerebrospinal fluid in the pathogenesis of wearing-off phenomenon in Parkinson's disease
    • Tohgi H, Abe T, Kikuchi T et al (1991a) The significance of 3-O-methyldopa concentrations in the cerebrospinal fluid in the pathogenesis of wearing-off phenomenon in Parkinson's disease. Neurosci Lett 132:19-22
    • (1991) Neurosci Lett , vol.132 , pp. 19-22
    • Tohgi, H.1    Abe, T.2    Kikuchi, T.3
  • 14
    • 0023181117 scopus 로고
    • 3-O-methyldopa and motor fluctuations in Parkinson's disease
    • Fabbrini G, Juncos JL, Mouradian MM et al (1987) 3-O-methyldopa and motor fluctuations in Parkinson's disease. Neurology 37:856-859
    • (1987) Neurology , vol.37 , pp. 856-859
    • Fabbrini, G.1    Juncos, J.L.2    Mouradian, M.M.3
  • 15
    • 0034725156 scopus 로고    scopus 로고
    • The O-methylated derivative of l-DOPA, 3-O-methyl-l-DOPA, fails to inhibit neuronal and non-neuronal aromatic l-amino acid decarboxylase
    • Soares-da-Silva P, Parada A, Serrao P (2000) The O-methylated derivative of l-DOPA, 3-O-methyl-l-DOPA, fails to inhibit neuronal and non-neuronal aromatic l-amino acid decarboxylase. Brain Res 863:293-297
    • (2000) Brain Res , vol.863 , pp. 293-297
    • Soares-Da-Silva, P.1    Parada, A.2    Serrao, P.3
  • 16
    • 0019985169 scopus 로고
    • 3-O-methyldopa blocks dopa metabolism in rat corpus striatum
    • Reches A, Fahn S (1982) 3-O-methyldopa blocks dopa metabolism in rat corpus striatum. Ann Neurol 12:267-271
    • (1982) Ann Neurol , vol.12 , pp. 267-271
    • Reches, A.1    Fahn, S.2
  • 17
    • 0031126766 scopus 로고    scopus 로고
    • Levodopa and 3-O-methyldopa in cerebrospinal fluid after levodopa-carbidopa association
    • Benetello P, Furlanut M, Fortunato M et al (1997) Levodopa and 3-O-methyldopa in cerebrospinal fluid after levodopa-carbidopa association. Pharmacol Res 35:313-315
    • (1997) Pharmacol Res , vol.35 , pp. 313-315
    • Benetello, P.1    Furlanut, M.2    Fortunato, M.3
  • 18
    • 0030746734 scopus 로고    scopus 로고
    • Levels of l-methionine S-adenosyltransferase activity in erythrocytes and concentrations of S-adenosylmethionine and S-adenosylhomocysteine in whole blood of patients with Parkinson's disease
    • Cheng H, Gomes-Trolin C, Aquilonius SM et al (1997) Levels of l-methionine S-adenosyltransferase activity in erythrocytes and concentrations of S-adenosylmethionine and S-adenosylhomocysteine in whole blood of patients with Parkinson's disease. Exp Neurol 145:580-585
    • (1997) Exp Neurol , vol.145 , pp. 580-585
    • Cheng, H.1    Gomes-Trolin, C.2    Aquilonius, S.M.3
  • 19
    • 0034853461 scopus 로고    scopus 로고
    • L-dopa upregulates the expression and activities of methionine adenosyl transferase and catechol-O-methyltransferase
    • Zhao WQ, Latinwo L, Liu XX et al (2001) l-dopa upregulates the expression and activities of methionine adenosyl transferase and catechol-O- methyltransferase. Exp Neurol 171:127-138
    • (2001) Exp Neurol , vol.171 , pp. 127-138
    • Zhao, W.Q.1    Latinwo, L.2    Liu, X.X.3
  • 20
    • 0028810238 scopus 로고
    • Effects of 3-O-methyl on l-dopa-facilitated synthesis and efflux of dopamine from rat striatal slices
    • Chang WY, Webster RA (1995) Effects of 3-O-methyl on l-dopa-facilitated synthesis and efflux of dopamine from rat striatal slices. Br J Pharmacol 116:2637-2640
    • (1995) Br J Pharmacol , vol.116 , pp. 2637-2640
    • Chang, W.Y.1    Webster, R.A.2
  • 21
    • 0027462802 scopus 로고
    • Levodopa toxicity in foetal rat midbrain neurons in culture: Modulation by ascorbic acid
    • Mena MA, Pardo B, Paino CL et al (1993) Levodopa toxicity in foetal rat midbrain neurons in culture: modulation by ascorbic acid. Neuroreport 4:438-440
    • (1993) Neuroreport , vol.4 , pp. 438-440
    • Mena, M.A.1    Pardo, B.2    Paino, C.L.3
  • 22
    • 0029915162 scopus 로고    scopus 로고
    • Glia conditioned medium protects fetal rat midbrain neurones in culture from l-DOPA toxicity
    • Mena MA, Casarejos MJ, Carazo A et al (1996) Glia conditioned medium protects fetal rat midbrain neurones in culture from l-DOPA toxicity. Neuroreport 7:441-445
    • (1996) Neuroreport , vol.7 , pp. 441-445
    • Mena, M.A.1    Casarejos, M.J.2    Carazo, A.3
  • 23
    • 0035353737 scopus 로고    scopus 로고
    • Chronic l-DOPA administration is not toxic to the remaining dopaminergic nigrostriatal neurons, but instead may promote their functional recovery, in rats with partial 6-OHDA or FeCl(3) nigrostriatal lesions
    • Datla KP, Blunt SB, Dexter DT (2001) Chronic l-DOPA administration is not toxic to the remaining dopaminergic nigrostriatal neurons, but instead may promote their functional recovery, in rats with partial 6-OHDA or FeCl(3) nigrostriatal lesions. Mov Disord 16:424-434
    • (2001) Mov Disord , vol.16 , pp. 424-434
    • Datla, K.P.1    Blunt, S.B.2    Dexter, D.T.3
  • 25
    • 0031968959 scopus 로고    scopus 로고
    • Chronic levodopa is not toxic for remaining dopamine neurons, but instead promotes their recovery, in rats with moderate nigrostriatal lesions
    • Murer MG, Dziewczapolski G, Menalled LB et al (1998) Chronic levodopa is not toxic for remaining dopamine neurons, but instead promotes their recovery, in rats with moderate nigrostriatal lesions. Ann Neurol 43:561-575
    • (1998) Ann Neurol , vol.43 , pp. 561-575
    • Murer, M.G.1    Dziewczapolski, G.2    Menalled, L.B.3
  • 26
    • 0029051317 scopus 로고
    • Induction of apoptosis in catecholaminergic PC12 cells by l-DOPA. Implications for the treatment of Parkinson's disease
    • Walkinshaw G, Waters CM (1995) Induction of apoptosis in catecholaminergic PC12 cells by l-DOPA. Implications for the treatment of Parkinson's disease. J Clin Invest 95:2458-2464
    • (1995) J Clin Invest , vol.95 , pp. 2458-2464
    • Walkinshaw, G.1    Waters, C.M.2
  • 27
    • 0036186658 scopus 로고    scopus 로고
    • 3-OMD and homocysteine plasma levels in parkinsonian patients
    • Müller T, Woitalla D, Fowler B et al (2002) 3-OMD and homocysteine plasma levels in parkinsonian patients. J Neural Transm 109:175-179
    • (2002) J Neural Transm , vol.109 , pp. 175-179
    • Müller, T.1    Woitalla, D.2    Fowler, B.3
  • 28
    • 0035958821 scopus 로고    scopus 로고
    • Decrease of methionine and S-adenosylmethionine and increase of homocysteine in treated patients with Parkinson's disease
    • Müller T, Woitalla D, Hauptmann B et al (2001) Decrease of methionine and S-adenosylmethionine and increase of homocysteine in treated patients with Parkinson's disease. Neurosci Lett 308:54-56
    • (2001) Neurosci Lett , vol.308 , pp. 54-56
    • Müller, T.1    Woitalla, D.2    Hauptmann, B.3
  • 29
    • 20344396838 scopus 로고    scopus 로고
    • Effects of homocysteine on the dopaminergic system and behavior in rodents
    • Lee ES, Chen H, Soliman KF et al (2005) Effects of homocysteine on the dopaminergic system and behavior in rodents. Neurotoxicology 26:361-371
    • (2005) Neurotoxicology , vol.26 , pp. 361-371
    • Lee, E.S.1    Chen, H.2    Soliman, K.F.3
  • 30
    • 0028081018 scopus 로고
    • Intense oxidative DNA damage promoted by l-dopa and its metabolites. Implications for neurodegenerative disease
    • Spencer JP, Jenner A, Aruoma OI et al (1994) Intense oxidative DNA damage promoted by l-dopa and its metabolites. Implications for neurodegenerative disease. FEBS Lett 353:246-250
    • (1994) FEBS Lett , vol.353 , pp. 246-250
    • Spencer, J.P.1    Jenner, A.2    Aruoma, O.I.3
  • 32
    • 0032852976 scopus 로고    scopus 로고
    • Determination of hydroxyl free radical formation in human platelets using high-performance liquid chromatography with electrochemical detection
    • Blandini F, Martignoni E, Ricotti R et al (1999) Determination of hydroxyl free radical formation in human platelets using high-performance liquid chromatography with electrochemical detection. J Chromatogr B Biomed Sci Appl 732:213-220
    • (1999) J Chromatogr B Biomed Sci Appl , vol.732 , pp. 213-220
    • Blandini, F.1    Martignoni, E.2    Ricotti, R.3
  • 33
    • 0141888290 scopus 로고    scopus 로고
    • Aggravation of l-DOPA-induced neurotoxicity by tetrahydropapaveroline in PC12 cells
    • Lee JJ, Kim YM, Yin SY et al (2003) Aggravation of l-DOPA-induced neurotoxicity by tetrahydropapaveroline in PC12 cells. Biochem Pharmacol 66:1787-1795
    • (2003) Biochem Pharmacol , vol.66 , pp. 1787-1795
    • Lee, J.J.1    Kim, Y.M.2    Yin, S.Y.3
  • 34
    • 0030338162 scopus 로고    scopus 로고
    • Catecholamines and indoleamines in the central nervous system of a urodele amphibian: A microdissection study with emphasis on the distribution of epinephrine
    • Lowry CA, Renner KJ, Moore FL (1996) Catecholamines and indoleamines in the central nervous system of a urodele amphibian: a microdissection study with emphasis on the distribution of epinephrine. Brain Behav Evol 48:70-93
    • (1996) Brain Behav Evol , vol.48 , pp. 70-93
    • Lowry, C.A.1    Renner, K.J.2    Moore, F.L.3
  • 35
    • 0021285442 scopus 로고
    • 3H]SCH 23390, a selective D1 receptor antagonist ligand, in rat striatum
    • 3H]SCH 23390, a selective D1 receptor antagonist ligand, in rat striatum. Life Sci 35:1885-1893
    • (1984) Life Sci , vol.35 , pp. 1885-1893
    • Billard, W.1    Ruperto, V.2    Crosby, G.3
  • 36
  • 37
    • 0031773366 scopus 로고    scopus 로고
    • Catecholamines potentiate amyloid beta-peptide neurotoxicity: Involvement of oxidative stress, mitochondrial dysfunction, and perturbed calcium homeostasis
    • Fu W, Luo H, Parthasarathy S et al (1998) Catecholamines potentiate amyloid beta-peptide neurotoxicity: involvement of oxidative stress, mitochondrial dysfunction, and perturbed calcium homeostasis. Neurobiol Dis 5:229-243
    • (1998) Neurobiol Dis , vol.5 , pp. 229-243
    • Fu, W.1    Luo, H.2    Parthasarathy, S.3
  • 38
    • 0029925338 scopus 로고    scopus 로고
    • Continuous monitoring of mitochondrial membrane potential in hepatocyte cell suspensions
    • Palmeira CM, Moreno AJ, Madeira VM et al (1996) Continuous monitoring of mitochondrial membrane potential in hepatocyte cell suspensions. J Pharmacol Toxicol Methods 35:35-43
    • (1996) J Pharmacol Toxicol Methods , vol.35 , pp. 35-43
    • Palmeira, C.M.1    Moreno, A.J.2    Madeira, V.M.3
  • 39
    • 0036160538 scopus 로고    scopus 로고
    • + on membrane permeability in brain mitochondria and cell viability in PC12 cells
    • + on membrane permeability in brain mitochondria and cell viability in PC12 cells. Neurochem Int 40:361-369
    • (2002) Neurochem Int , vol.40 , pp. 361-369
    • Lee, C.S.1    Han, J.H.2    Jang, Y.Y.3
  • 40
    • 0018960332 scopus 로고
    • Catechol-O-methyltransferase activity: A determinant of levodopa response
    • Reilly DK, Rivera-Calimlim L, Van Dyke D (1980) Catechol-O- methyltransferase activity: a determinant of levodopa response. Clin Pharmacol Ther 28:278-286
    • (1980) Clin Pharmacol Ther , vol.28 , pp. 278-286
    • Reilly, D.K.1    Rivera-Calimlim, L.2    Van Dyke, D.3
  • 41
    • 0017348146 scopus 로고
    • The clinical picture and plasma levodopa metabolite profile of parkinsonian nonresponders. Treatment with levodopa and decarboxylase inhibitor
    • Rivera-Calimlim L, Tandon D, Anderson F et al (1977) The clinical picture and plasma levodopa metabolite profile of parkinsonian nonresponders. Treatment with levodopa and decarboxylase inhibitor. Arch Neurol 34:228-232
    • (1977) Arch Neurol , vol.34 , pp. 228-232
    • Rivera-Calimlim, L.1    Tandon, D.2    Anderson, F.3
  • 42
    • 0032809060 scopus 로고    scopus 로고
    • Interaction between l-DOPA and 3-O-methyl-l-DOPA for transport in immortalised rat capillary cerebral endothelial cells
    • Gomes P, Soares-da-Silva P (1999) Interaction between l-DOPA and 3-O-methyl-l-DOPA for transport in immortalised rat capillary cerebral endothelial cells. Neuropharmacology 38:1371-1380
    • (1999) Neuropharmacology , vol.38 , pp. 1371-1380
    • Gomes, P.1    Soares-Da-Silva, P.2
  • 43
    • 0028082343 scopus 로고
    • 3-O-methyldopa attenuates the effects of Madopar on the haloperidol-induced cataleptic behavior and the locomotor activity in the mouse
    • Himori N, Tanaka Y, Kurasawa M et al (1994) 3-O-methyldopa attenuates the effects of Madopar on the haloperidol-induced cataleptic behavior and the locomotor activity in the mouse. Pharmacology 48:226-233
    • (1994) Pharmacology , vol.48 , pp. 226-233
    • Himori, N.1    Tanaka, Y.2    Kurasawa, M.3
  • 44
    • 0017624823 scopus 로고
    • Release of (3H)norepinephrine from a clonal line of pheochromocytoma cells (PC12) by nicotinic cholinergic stimulation
    • Greene LA, Rein G (1977) Release of (3H)norepinephrine from a clonal line of pheochromocytoma cells (PC12) by nicotinic cholinergic stimulation. Brain Res 138:521-528
    • (1977) Brain Res , vol.138 , pp. 521-528
    • Greene, L.A.1    Rein, G.2
  • 45
    • 0037934795 scopus 로고
    • Storage and release of acetylcholine by a clonal cell line
    • Schubert D, Klier FG (1977) Storage and release of acetylcholine by a clonal cell line. Proc Natl Acad Sci USA 74:5184-5188
    • (1977) Proc Natl Acad Sci USA , vol.74 , pp. 5184-5188
    • Schubert, D.1    Klier, F.G.2
  • 46
    • 0019308385 scopus 로고
    • Storage of dopamine and acetylcholine in granules of PC12, a clonal pheochromocytoma cell line
    • Rebois RV, Reynolds EE, Toll L et al (1980) Storage of dopamine and acetylcholine in granules of PC12, a clonal pheochromocytoma cell line. Biochemistry 19:1240-1248
    • (1980) Biochemistry , vol.19 , pp. 1240-1248
    • Rebois, R.V.1    Reynolds, E.E.2    Toll, L.3
  • 47
    • 0345704610 scopus 로고
    • Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
    • Greene LA, Tischler AS (1976) Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci USA 73:2424-2428
    • (1976) Proc Natl Acad Sci USA , vol.73 , pp. 2424-2428
    • Greene, L.A.1    Tischler, A.S.2
  • 48
    • 0028834192 scopus 로고
    • L-dopa cytotoxicity to PC12 cells in culture is via its autoxidation
    • Basma AN, Morris EJ, Nicklas WJ, Geller HM (1995) l-dopa cytotoxicity to PC12 cells in culture is via its autoxidation. J Neurochem 64:825-832
    • (1995) J Neurochem , vol.64 , pp. 825-832
    • Basma, A.N.1    Morris, E.J.2    Nicklas, W.J.3    Geller, H.M.4
  • 49
    • 0028176878 scopus 로고
    • + in PC12 cells: Insights into potential neurotoxicants in Parkinson's disease
    • + in PC12 cells: insights into potential neurotoxicants in Parkinson's disease. J Neurochem 62:1503-1510
    • (1994) J Neurochem , vol.62 , pp. 1503-1510
    • Cobuzzi, R.J.1    Neafsey, E.J.2    Collins, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.