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Volumn 110, Issue 8, 2003, Pages 911-922

Modifications of plasma and platelet levels of L-DOPA and its direct metabolites during treatment with tolcapone or entacapone in patients with Parkinson's disease

Author keywords

3 O methyldopa; Catechol O methyltransferase; Dopamine; Extracellular; Intracellular

Indexed keywords

3 O METHYLDOPA; CATECHOL METHYLTRANSFERASE; DOPAMINE; ENTACAPONE; LEVODOPA; TOLCAPONE;

EID: 10744223966     PISSN: 03009564     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00702-003-0004-z     Document Type: Article
Times cited : (12)

References (46)
  • 1
    • 70449211682 scopus 로고
    • O-methylation of catecholamines in vivo
    • Axelrod J, Senoh S, Witcop B (1958) O-methylation of catecholamines in vivo. J Biol Chem 233: 697-701
    • (1958) J Biol Chem , vol.233 , pp. 697-701
    • Axelrod, J.1    Senoh, S.2    Witcop, B.3
  • 2
    • 0030656298 scopus 로고    scopus 로고
    • Simultaneous determination of L-dopa and 3-O-methyldopa in human platelets and plasma using high-performance liquid chromatography with electrochemical detection
    • Blandini F, Martignoni E, Pacchetti C, Desideri S, Rivellini D, Nappi G (1997) Simultaneous determination of L-dopa and 3-O-methyldopa in human platelets and plasma using high-performance liquid chromatography with electrochemical detection. J Chromatogr B Biomed Sci Appl 700: 278-282
    • (1997) J Chromatogr B Biomed Sci Appl , vol.700 , pp. 278-282
    • Blandini, F.1    Martignoni, E.2    Pacchetti, C.3    Desideri, S.4    Rivellini, D.5    Nappi, G.6
  • 3
    • 0032949477 scopus 로고    scopus 로고
    • New, selective catechol-O-methyltransferase inhibitors as therapeutic agents in Parkinson's disease
    • Bonifati V, Meco G (1999) New, selective catechol-O-methyltransferase inhibitors as therapeutic agents in Parkinson's disease. Pharmacol Ther 81: 1-36
    • (1999) Pharmacol Ther , vol.81 , pp. 1-36
    • Bonifati, V.1    Meco, G.2
  • 4
    • 0036489157 scopus 로고    scopus 로고
    • 18F-dopa PET evidence that tolcapone acts as a central COMT inhibitor in Parkinson's disease
    • Ceravolo R, Piccini P, Bailey DL, Jorga KM, Bryson H, Brooks DJ (2002) 18F-dopa PET evidence that tolcapone acts as a central COMT inhibitor in Parkinson's disease. Synapse 43: 201-207
    • (2002) Synapse , vol.43 , pp. 201-207
    • Ceravolo, R.1    Piccini, P.2    Bailey, D.L.3    Jorga, K.M.4    Bryson, H.5    Brooks, D.J.6
  • 5
    • 0028907751 scopus 로고
    • Improved therapy of Parkinson's disease by tolcapone, a central and peripheral COMT inhibitor with an S-adenosyl-L-methionine sparing effect
    • Da Prada M, Borgulya J, Napolitano A, Zurcher G (1994) Improved therapy of Parkinson's disease by tolcapone, a central and peripheral COMT inhibitor with an S-adenosyl-L-methionine sparing effect. Clin Neuropharmacol 17[Suppl 3]: S26-S37
    • (1994) Clin Neuropharmacol , vol.17 , Issue.3 SUPPL.
    • Da Prada, M.1    Borgulya, J.2    Napolitano, A.3    Zurcher, G.4
  • 6
    • 0024402941 scopus 로고
    • Dopamine uptake by platelets is selective, temperature dependent and not influenced by the dopamine-D1 or dopamine-D2 receptor
    • Dean B, Copolov DL (1989) Dopamine uptake by platelets is selective, temperature dependent and not influenced by the dopamine-D1 or dopamine-D2 receptor. Life Sci 45: 401-411
    • (1989) Life Sci , vol.45 , pp. 401-411
    • Dean, B.1    Copolov, D.L.2
  • 7
    • 0031415076 scopus 로고    scopus 로고
    • Cathecol-O-methyltransferase inhibitors: Clinical potential in the treatment of Parkinson's disease
    • Dingemanse J (1997) Cathecol-O-methyltransferase inhibitors: clinical potential in the treatment of Parkinson's disease. Drug Dev Res 42: 1-25
    • (1997) Drug Dev Res , vol.42 , pp. 1-25
    • Dingemanse, J.1
  • 8
    • 0034642349 scopus 로고    scopus 로고
    • Issues important for rational COMT inhibition
    • Dingemanse J (2000) Issues important for rational COMT inhibition. Neurology 55[Suppl 4]: S24-S27
    • (2000) Neurology , vol.55 , Issue.4 SUPPL.
    • Dingemanse, J.1
  • 9
    • 0029044201 scopus 로고
    • Integrated pharmacokinetics and pharmacodynamics of the novel catechol-O-methyltransferase inhibitor tolcapone during first administration to humans
    • Dingemanse J, Jorga KM, Schmitt M, Gieschke R, Fotteler B, Zurcher G, Da Prada M, van Brummelen P (1995) Integrated pharmacokinetics and pharmacodynamics of the novel catechol-O-methyltransferase inhibitor tolcapone during first administration to humans. Clin Pharmacol Ther 57: 508-517
    • (1995) Clin Pharmacol Ther , vol.57 , pp. 508-517
    • Dingemanse, J.1    Jorga, K.M.2    Schmitt, M.3    Gieschke, R.4    Fotteler, B.5    Zurcher, G.6    Da Prada, M.7    Van Brummelen, P.8
  • 10
    • 0034816337 scopus 로고    scopus 로고
    • Long-term comparative experience with tolcapone and entacapone in advanced Parkinson's disease
    • Factor SA, Molho ES, Feustel PJ, Brown DL, Evans SM (2001) Long-term comparative experience with tolcapone and entacapone in advanced Parkinson's disease. Clin Neuropharmacol 24: 295-299
    • (2001) Clin Neuropharmacol , vol.24 , pp. 295-299
    • Factor, S.A.1    Molho, E.S.2    Feustel, P.J.3    Brown, D.L.4    Evans, S.M.5
  • 11
    • 0000224448 scopus 로고
    • Unified Parkinson's Disease Rating Scale
    • Fahn S, Marsden CD, Calne DB, Goldstein M (eds). MacMillian Healthcare Information, Florham Park, NJ
    • Fahn S, Elton RL and UPDRS Committee (1987) Unified Parkinson's Disease Rating Scale. In: Fahn S, Marsden CD, Calne DB, Goldstein M (eds) Recent developments in Parkinson's disease. MacMillian Healthcare Information, Florham Park, NJ, pp 153-163
    • (1987) Recent Developments in Parkinson's Disease , pp. 153-163
    • Fahn, S.1    Elton, R.L.2
  • 12
    • 0031900188 scopus 로고    scopus 로고
    • Influence of COMT inhibition on levodopa pharmacology and therapy
    • Goetz CG (1998) Influence of COMT inhibition on levodopa pharmacology and therapy. Neurology 50[Suppl 5]: S26-S30
    • (1998) Neurology , vol.50 , Issue.5 SUPPL.
    • Goetz, C.G.1
  • 13
    • 0032809060 scopus 로고    scopus 로고
    • Interaction between L-DOPA and 3-O-methyl-L-DOPA for transport in immortalised rat capillary cerebral endothelial cells
    • Gomes P, Soares-da-Silva P (1999) Interaction between L-DOPA and 3-O-methyl-L-DOPA for transport in immortalised rat capillary cerebral endothelial cells. Neuropharmacology 38: 1371-1380
    • (1999) Neuropharmacology , vol.38 , pp. 1371-1380
    • Gomes, P.1    Soares-Da-Silva, P.2
  • 15
    • 0019123620 scopus 로고
    • Benserazide and carbidopa as substrates of catechol-O-methyltransferase: New mechanism of action in Parkinson's disease
    • Hagan RM, Raxworhty MJ, Gulliver PA (1980) Benserazide and carbidopa as substrates of catechol-O-methyltransferase: new mechanism of action in Parkinson's disease. Biochem Pharmacol 29: 3123-3126
    • (1980) Biochem Pharmacol , vol.29 , pp. 3123-3126
    • Hagan, R.M.1    Raxworhty, M.J.2    Gulliver, P.A.3
  • 16
    • 0027485236 scopus 로고
    • The transport of L-6-fluorodopa and its metabolites from blood to cerebrospinal fluid and brain
    • Hammerstad JP, Pate BD, Hewitt KA, Chan GL, Ruth TJ, Calne DB (1993) The transport of L-6-fluorodopa and its metabolites from blood to cerebrospinal fluid and brain. Ann Neurol 34: 603-608
    • (1993) Ann Neurol , vol.34 , pp. 603-608
    • Hammerstad, J.P.1    Pate, B.D.2    Hewitt, K.A.3    Chan, G.L.4    Ruth, T.J.5    Calne, D.B.6
  • 17
    • 0014082977 scopus 로고
    • Parkinsonism: Onset, progression and mortality
    • Hoehn MM, Yahr MD (1967) Parkinsonism: onset, progression and mortality. Neurology 17: 427-442
    • (1967) Neurology , vol.17 , pp. 427-442
    • Hoehn, M.M.1    Yahr, M.D.2
  • 18
    • 0042393522 scopus 로고    scopus 로고
    • Clinical pharmacology of COMT-inhibitors: Differences and similarities between entacapone and tolcapone
    • Jorga KM, Fotteler B (1996) Clinical pharmacology of COMT-inhibitors: differences and similarities between entacapone and tolcapone. Acta Neurol Scand 94[Suppl 167]: 8
    • (1996) Acta Neurol Scand , vol.94 , Issue.167 SUPPL. , pp. 8
    • Jorga, K.M.1    Fotteler, B.2
  • 19
    • 0026526135 scopus 로고
    • Levodopa: Pharmacology, pharmacokinetics and pharmacodynamics
    • Juncos JL (1992) Levodopa: pharmacology, pharmacokinetics and pharmacodynamics. Neurol Clin 10: 487-509
    • (1992) Neurol Clin , vol.10 , pp. 487-509
    • Juncos, J.L.1
  • 20
    • 0034095886 scopus 로고    scopus 로고
    • Clinical pharmacology, therapeutic use and potential of COMT inhibitors in Parkinson's disease
    • Kaakkola S (2000) Clinical pharmacology, therapeutic use and potential of COMT inhibitors in Parkinson's disease. Drugs 59: 1233-1250
    • (2000) Drugs , vol.59 , pp. 1233-1250
    • Kaakkola, S.1
  • 21
    • 0027492354 scopus 로고
    • Effects of catechol-O-methyltransferase inhibitors and L-3,4-dihydroxyphenylalanine with or without carbidopa on extracellular dopamine in rat striatum
    • Kaakkola S, Wurtman RJ (1993) Effects of catechol-O-methyltransferase inhibitors and L-3,4-dihydroxyphenylalanine with or without carbidopa on extracellular dopamine in rat striatum. J Neurochem 60: 137-144
    • (1993) J Neurochem , vol.60 , pp. 137-144
    • Kaakkola, S.1    Wurtman, R.J.2
  • 24
    • 0034642346 scopus 로고    scopus 로고
    • Benefits of COMT inhibitors in levodopa-treated parkinsonian patients. Results of clinical trials
    • Kieburtz K, Hubble J (2000) Benefits of COMT inhibitors in levodopa-treated parkinsonian patients. Results of clinical trials. Neurology 55[Suppl 4]: S42-S45
    • (2000) Neurology , vol.55 , Issue.4 SUPPL.
    • Kieburtz, K.1    Hubble, J.2
  • 25
    • 0031923914 scopus 로고    scopus 로고
    • COMT inhibition: A new strategy for Parkinson's disease
    • Kurth MA, Adler CH (1998) COMT inhibition: a new strategy for Parkinson's disease. Neurology 50[Suppl 5]: S3-S14
    • (1998) Neurology , vol.50 , Issue.5 SUPPL.
    • Kurth, M.A.1    Adler, C.H.2
  • 26
    • 0035133553 scopus 로고    scopus 로고
    • Molecular mechanism controlling the rate and specificity of catechol-O-methylation by human soluble catechol-O-methyltransferase
    • Lautala P, Ulmanen I, Taskinen J (2001) Molecular mechanism controlling the rate and specificity of catechol-O-methylation by human soluble catechol-O-methyltransferase. Mol Pharmacol 59: 393-402
    • (2001) Mol Pharmacol , vol.59 , pp. 393-402
    • Lautala, P.1    Ulmanen, I.2    Taskinen, J.3
  • 27
    • 0025039417 scopus 로고
    • Rationale for selective COMT inhibitors as adjuvants in the drug treatment of Parkinson's disease
    • Mannisto PT, Kaakkola S (1990) Rationale for selective COMT inhibitors as adjuvants in the drug treatment of Parkinson's disease. Pharmacol Toxicol 66: 317-323
    • (1990) Pharmacol Toxicol , vol.66 , pp. 317-323
    • Mannisto, P.T.1    Kaakkola, S.2
  • 28
    • 0038287034 scopus 로고    scopus 로고
    • Catechol-O-methyltransferase (COMT): Biochemistry, molecular biology, pharmacology and clinical efficacy of the new selective COMT inhibitors
    • Mannisto PT, Kaakkola S (1999) Catechol-O-methyltransferase (COMT): biochemistry, molecular biology, pharmacology and clinical efficacy of the new selective COMT inhibitors. Pharmacol Rev 51: 593-628
    • (1999) Pharmacol Rev , vol.51 , pp. 593-628
    • Mannisto, P.T.1    Kaakkola, S.2
  • 30
    • 0345647071 scopus 로고    scopus 로고
    • Extending levodopa action - COMT inhibition
    • Martínez-Martín P, O'Brien CF (1998) Extending levodopa action - COMT inhibition. Neurology 50[Suppl 6]: S27-S32
    • (1998) Neurology , vol.50 , Issue.6 SUPPL.
    • Martínez-Martín, P.1    O'Brien, C.F.2
  • 32
    • 0028815750 scopus 로고
    • Effects of tolcapone, a novel catechol-O-methyltransferase inhibitor, on striatal metabolism of L-dopa and dopamine in rats
    • Napolitano A, Zurcher G, Da Prada M (1995) Effects of tolcapone, a novel catechol-O-methyltransferase inhibitor, on striatal metabolism of L-dopa and dopamine in rats. Eur J Pharmacol 273: 215-221
    • (1995) Eur J Pharmacol , vol.273 , pp. 215-221
    • Napolitano, A.1    Zurcher, G.2    Da Prada, M.3
  • 33
    • 0034642337 scopus 로고    scopus 로고
    • Effect of COMT inhibition on the pharmacokinetics and pharmacodynamics of levodopa in parkinsonian patients
    • Nutt JG (2000) Effect of COMT inhibition on the pharmacokinetics and pharmacodynamics of levodopa in parkinsonian patients. Neurology 55[Suppl 4]: S33-S37
    • (2000) Neurology , vol.55 , Issue.4 SUPPL.
    • Nutt, J.G.1
  • 34
    • 0013695875 scopus 로고    scopus 로고
    • Elevated serum levels of dihydroxyphenylacetic acid (DOPAC) and dopamine after catechol-O-methyltransferase (COMT) inhibition
    • Oechsner M, Sturenburg HJ, Buhmann C, Muller D, Kunze K (1998) Elevated serum levels of dihydroxyphenylacetic acid (DOPAC) and dopamine after catechol-O-methyltransferase (COMT) inhibition. Eur J Neurol 5[Suppl 3]: S169
    • (1998) Eur J Neurol , vol.5 , Issue.3 SUPPL.
    • Oechsner, M.1    Sturenburg, H.J.2    Buhmann, C.3    Muller, D.4    Kunze, K.5
  • 35
    • 0033977448 scopus 로고    scopus 로고
    • Tolcapone and hepatotoxic effects. Tasmar Advisory Panel
    • Olanow CW (2000) Tolcapone and hepatotoxic effects. Tasmar Advisory Panel. Arch Neurol 57: 263-267
    • (2000) Arch Neurol , vol.57 , pp. 263-267
    • Olanow, C.W.1
  • 36
    • 0034973443 scopus 로고    scopus 로고
    • An algorithm (decision tree) for the management of Parkinson's disease (2001): Treatment guidelines
    • Olanow CW, Watts RL, Koller WC (2001) An algorithm (decision tree) for the management of Parkinson's disease (2001): treatment guidelines. Neurology 56[11 Suppl 5]: S1-S88
    • (2001) Neurology , vol.56 , Issue.11 SUPPL. 5
    • Olanow, C.W.1    Watts, R.L.2    Koller, W.C.3
  • 37
    • 0027330930 scopus 로고
    • 3H] dopamine uptake by platelet storage granules in Parkinson's disease
    • 3H] dopamine uptake by platelet storage granules in Parkinson's disease. Life Sci 53: 1753-1759
    • (1993) Life Sci , vol.53 , pp. 1753-1759
    • Rabey, J.M.1    Shabtai, H.2    Graff, E.3    Oberman, Z.4
  • 38
    • 0019985169 scopus 로고
    • 3-O-methyldopa blocks dopa metabolism in rat corpus striatum
    • Reches A, Fahn S (1982) 3-O-methyldopa blocks dopa metabolism in rat corpus striatum. Ann Neurol 12: 267-271
    • (1982) Ann Neurol , vol.12 , pp. 267-271
    • Reches, A.1    Fahn, S.2
  • 40
    • 0031708101 scopus 로고    scopus 로고
    • COMT inhibition in the treatment of Parkinson's disease
    • Ruottinen HM, Rinne UK (1998) COMT inhibition in the treatment of Parkinson's disease. J Neurol 245[Suppl 3]: P25-P34
    • (1998) J Neurol , vol.245 , Issue.3 SUPPL.
    • Ruottinen, H.M.1    Rinne, U.K.2
  • 42
    • 0034642335 scopus 로고    scopus 로고
    • The place of COMT inhibitors in the armamentarium of drugs for the treatment of Parkinson's disease
    • Schapira AHV, Obeso JA, Olanow CW (2000) The place of COMT inhibitors in the armamentarium of drugs for the treatment of Parkinson's disease. Neurology 55[Suppl 4]: S65-S68
    • (2000) Neurology , vol.55 , Issue.4 SUPPL.
    • Schapira, A.H.V.1    Obeso, J.A.2    Olanow, C.W.3
  • 43
    • 0035225222 scopus 로고    scopus 로고
    • Catechol-O-methyltransferase inhibitors in Parkinson's disease
    • Teravainen H, Rinne U, Gordin A (2001) Catechol-O-methyltransferase inhibitors in Parkinson's disease. Adv Neurol 86: 311-325
    • (2001) Adv Neurol , vol.86 , pp. 311-325
    • Teravainen, H.1    Rinne, U.2    Gordin, A.3
  • 44
    • 0029943947 scopus 로고    scopus 로고
    • Minor effect of tolcapone, a catechol-O-methyltransferase inhibitor, on extracellular dopamine levels modified by amphetamine or pargyline: A microdialysis study in anaesthetized rats
    • Tuomainen P, Tornwall M, Mannisto PT (1996) Minor effect of tolcapone, a catechol-O-methyltransferase inhibitor, on extracellular dopamine levels modified by amphetamine or pargyline: a microdialysis study in anaesthetized rats. Pharmacol Toxicol 78: 392-396
    • (1996) Pharmacol Toxicol , vol.78 , pp. 392-396
    • Tuomainen, P.1    Tornwall, M.2    Mannisto, P.T.3
  • 45
    • 0016707704 scopus 로고
    • 3-O-methyldopa uptake and inhibition of L-DOPA at the blood-brain barrier
    • Wade LA, Katzman R (1975) 3-O-methyldopa uptake and inhibition of L-DOPA at the blood-brain barrier. Life Sci 17: 131-136
    • (1975) Life Sci , vol.17 , pp. 131-136
    • Wade, L.A.1    Katzman, R.2
  • 46
    • 0025157730 scopus 로고
    • Ro 40-7592, a novel, very potent, and orally active inhibitor of catechol-O-methyltransferase: A pharmacological study in rats
    • Zurcher G, Keller HH, Kettler R, Borgulya J, Bonetti EP, Eigenmann R, Da Prada M (1990) Ro 40-7592, a novel, very potent, and orally active inhibitor of catechol-O-methyltransferase: a pharmacological study in rats. Adv Neurol 53: 497-503
    • (1990) Adv Neurol , vol.53 , pp. 497-503
    • Zurcher, G.1    Keller, H.H.2    Kettler, R.3    Borgulya, J.4    Bonetti, E.P.5    Eigenmann, R.6    Da Prada, M.7


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