Opposite effect of phorbol ester PMA on PTGS2 and PGDH mRNA expression in human chorion trophoblast cells

Reproductive Sciences

Volumn 15, Issue 1, 2008, Pages 40-50

  Casciani, Valentina ^a,b   Marinoni, Emanuela ^b   Bocking, Alan D ^a   Moscarini, Massimo ^b   Di Iorio, Romolo ^b   Challis, John R G ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Calcium; Chorion; Mitogen activated protein kinase; Phorbol ester; Prostaglandins

Indexed keywords

15 HYDROXYPROSTAGLANDIN DEHYDROGENASE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CALCIMYCIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE P38; PHORBOL 13 ACETATE 12 MYRISTATE; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE 2; PROTEIN KINASE C; STRESS ACTIVATED PROTEIN KINASE; 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE; BISINDOLYLMALEIMIDE I; CALCIUM; CARCINOGEN; CYCLOOXYGENASE 2; ENZYME INHIBITOR; IMIDAZOLE DERIVATIVE; INDOLE DERIVATIVE; MALEIMIDE DERIVATIVE; MAP2K1 PROTEIN, HUMAN; MAP2K2 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PTGS2 PROTEIN, HUMAN; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHORION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; ENZYME REGULATION; FEMALE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TROPHOBLAST; UPREGULATION; CELL CULTURE; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; PREGNANCY; SIGNAL TRANSDUCTION;

CALCIUM; CARCINOGENS; CELLS, CULTURED; CHORION; CYCLOOXYGENASE 2; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; HYDROXYPROSTAGLANDIN DEHYDROGENASES; IMIDAZOLES; INDOLES; MALEIMIDES; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MAP KINASE KINASE 4; MAP KINASE SIGNALING SYSTEM; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PREGNANCY; PROTEIN KINASE C; PYRIDINES; RNA, MESSENGER; TETRADECANOYLPHORBOL ACETATE; TROPHOBLASTS;

EID: 38949115721     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719107309647     Document Type: Article

References (50)

1. Challis JRG, Matthews SG, Gibb W., Lye SJ Endocrine and paracrine regulation of birth at term and preterm. Endocr Rev. 2000 ; 21: 514-550.
2. Tanabe T., Tohnai N. Cyclooxygenase isozymes and their gene structures and expression. Prostaglandins Other Lipid Mediat. 2002 ; 68-69: 95-114.
3. Kelly RW Inflammatory mediators and parturition. Rev Reprod. 1996 ; 1: 89-96.
4. Hirst JJ, Teixeira FJ, Zakar T., Olson DM Prostaglandin endoperoxide-H synthase-1 and -2 messenger ribonucleic acid levels in human amnion with spontaneous labor onset. J Clin Endocrinol Metab. 1995 ; 80: 517-523.
5. Mijovic JE, Zakar T., Nairn TK, Olson DM Prostaglandin endoperoxide H synthase (PGHS) activity and PGHS-1 and -2 messenger ribonucleic acid abundance in human chorion throughout gestation and with preterm labor. J Clin Endocrinol Metab. 1998 ; 83: 1358-1367.
6. Mijovic JE, Zakar T., Angelova J., Olson DM Prostaglandin endoperoxide H synthase mRNA expression in the human amnion and decidua during pregnancy and in the amnion at preterm labour. Mol Hum Reprod. 1999 ; 5: 182-187.
7. Slater D., Dennes W., Sawdy R., AllportV., Bennett P. Expression of cyclo-oxygenase types-1 and -2 in human fetal membranes throughout pregnancy. J Mol Endocrinol. 1999 ; 22 (2). 125-130.
8. Sawdy RJ, Slater DM, Dennes WJ, Sullivan MH, Bennett PR The roles of the cyclo-oxygenases types one and two in prostaglandin synthesis in human fetal membranes at term. Placenta. 2000 ; 21 (1). 54-57.
9. Cheung PY, Walton JC, Tai HH, Riley SC, Challis JR Localization of 15-hydroxy prostaglandin dehydrogenase in human fetal membranes, decidua, and placenta during pregnancy. Gynecol Obstet Invest. 1992 ; 33: 142-146.
10. Sangha RK, Walton JC, Ensor CM, Tai HH, Challis JR Immunohistochemical localization, messenger ribonucleic acid abundance, and activity of 15-hydroxyprostaglandin dehydrogenase in placenta and fetal membranes during term and preterm labor. J Clin Endocrinol Metab. 1994 ; 78: 982-989.
11. Giannoulias D., Haluska GJ, Gravett MG, Sadowsky DW, Challis JR, Novy MJ Localization of prostaglandin H synthase, prostaglandin dehydrogenase, corticotropin releasing hormone and glucocorticoid receptor in rhesus monkey fetal membranes with labor and in the presence of infection. Placenta. 2005 ; 26: 289-297.
12. van Meir CA, Matthews SG, Keirse MJ, Ramirez MM, Bocking A., Challis JR 15-hydroxyprostaglandin dehydrogenase: implications in preterm labor with and without ascending infection. J Clin Endocrinol Metab. 1997 ; 82: 969-976.
13. Casciani V., Marinoni E., Di Iorio R., Challis JRG Opposite effect of extracellular calcium on PTGS2 and PGDH expression in human chorion trophoblast cells. Poster presented at: International Forum on Birth ; June 8-11, 2005 ; Rome, Italy.
14. Casciani V., Premyslova M., Marinoni E., Di Iorio R., Cosmi EV, Challis JRG Effect of extracellular calcium on the expression of PTGS2 and PGDH enzymes and on PGE2 output in human chorion trophoblast cells. Poster presented at: First SGI International Summit-Preterm Birth ; November 10-12, 2005 ; Siena, Italy.
15. Challis JR, Bloomfield FH, Bocking AD, et al. Fetal signals and parturition. J Obstet Gynaecol Res. 2005 ; 31 (6). 492-499.
16. Lundin-Schiller S., Mitchell MD Regulation of chorion laeve prostaglandin E2 production by epidermal growth factor, protein kinase C activation and calcium. Placenta. 1991 ; 12: 597-603.
17. Lytton FD, Mitchell MD Phorbol ester-induced stimulation of prostaglandin biosynthesis in human amnion cells. Biochim Biophys Acta. 1998 ; 959: 399-401.
18. Sander J., Myatt L. Regulation of prostaglandin E2 synthesis in human amnion by protein kinase C. Prostaglandins. 1990 ; 39: 355-363.
19. Kniss DA, Mershon J., Su HC, et al. Evidence of a role for protein kinase C in epidermal growth factor-induced prostaglandin E2 synthesis in amnion cells. Am J Obstet Gynecol. 1990 ; 163: 1883-1890.
20. Smieja Z., Zakar T., Olson DM Stimulation of cultured amnion cell prostaglandin endoperoxide H synthase activity by glucocorticoids and phorbol ester. Am J Obstet Gynecol. 1993 ; 169 (3). 653-661.
21. Mitchell MD The regulation of decidual prostaglandin biosynthesis by growth factors, phorbol esters, and calcium. Biol Reprod. 1991 ; 44: 871-874.
22. Zakar T., Mijovic JE, Eyster KM, Bhardwaj D., Olson DM Regulation of prostaglandin H2 synthase-2 expression in primary human amnion cells by tyrosine kinase dependent mechanisms. Biochim Biophys Acta. 1998 ; 1391: 37-51.
23. Trautman MS, Edwin SS, Collmer D., Dudley DJ, Simmons D., Mitchell MD Prostaglandin H synthase-2 in human gestational tissues: regulation in amnion. Placenta. 1996 ; 17: 239-245.
24. Cano E., Mahadevan LC Parallel signal processing among mammalian MAPKs. Trends Biochem Sci. 1995 ; 20: 117-122.
25. Kliman HJ, Nestler JE, Sermasi E., Sanger JM, Strauss JF III. Purification, characterization, and in vitro differentiation of cytotrophoblasts from human term placentae. Endocrinology. 1986 ; 118: 1567-1582.
26. LiW., Challis Jrg Corticotropin-releasing hormone and urocortin induce secretion of matrix metalloproteinase-9 (MMP-9) without change in tissue inhibitors of MMP-1 by cultured cells from human placenta and fetal membranes. J Clin Endocrinol Metab. 2005 ; 90 (12). 6569-6574.
27. Premyslova M., Chisaka H., Okamura K., Challis JR IL-1beta treatment does not co-ordinately up-regulate mPGES-1 and PTGS2 mRNA expression, but results in higher degree of cellular and intracellular co-localization of their immunoreactive proteins in human placenta trophoblast cells. Placenta. 2006 ; 27 (6-7). 576-586.
28. Vezza R., Habib A., Li H., Lawson JA, FitzGerald GA Regulation of cyclooxygenases by protein kinase C: evidence against the importance of direct enzyme phosphorylation. J Biol Chem. 1996 ; 271: 30028-30033.
29. Xun CQ, Ensor CM, Tai HH Regulation of synthesis and activity of NAD(+)-dependent 15-hydroxy-prostaglandin dehydrogenase (15-PGDH) by dexamethasone and phorbol ester in human erythroleukemia (HEL) cells. Biochem Biophys Res Commun. 1991 ; 177: 1258-1265.
30. Chang MS, Chen BC, Yu MT, Sheu JR, Chen TF, Lin CH Phorbol 12-myristate 13-acetate upregulates cyclooxygenase-2 expression in human pulmonary epithelial cells via Ras, Raf-1, ERK, and NF-kappaB, but not p38 MAPK, pathways. Cell Signal. 2005 ; 17: 299-310.
31. Xu L., Nishimura K., Jisaka M., Nagaya T., Yokota K. Gene expression of arachidonate cyclooxygenase pathway leading to the delayed synthesis of prostaglandins E2 and F2alpha in response to phorbol 12-myristate 13-acetate and action of these prostanoids during life cycle of adipocytes. Biochim Biophys Acta. 2006 ; 1761 (4). 434-444.
32. Kim JH, Lee KW, Lee MW, Lee HJ, Kim SH, Surh YJ Hirsutenone inhibits phorbol ester-induced upregulation of PTGS2 and MMP-9 in cultured human mammary epithelial cells: NF-kappaB as a potential molecular target. FEBS Lett. 2006 ; 580 (2). 385-392.
33. Inoue H., Yokoyama C., Hara S., Tone Y., Tanabe T. Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells: involvement of both nuclear factor for interleukin-6 expression site and cAMP response element. J Biol Chem. 1995 ; 270: 24965-24971.
34. Geng Y., Blanco FJ, Cornelisson M., Lotz M. Regulation of cyclooxygenase-2 expression in normal human articular chondrocytes. J Immunol. 1995 ; 155 (2). 796-801.
35. Xun CQ, Tian ZG, Tai HH Stimulation of synthesis de novo of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase in human promyelocytic leukaemia (HL-60) cells by phorbol ester. Biochem J. 1991 ; 279 (pt 2). 553-558.
36. Tong M., Tai HH Dexamethasone inhibits the induction of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase by phorbol ester in human promonocytic U937 cells. Biochim Biophys Acta. 2000 ; 1497: 61-68.
37. Tong M., Tai HH 15- Hydroxyprostaglandin dehydrogenase can be induced by dexamethasone and other glucocorticoids at the therapeutic level in A549 human lung adenocarcinoma cells. Arch Biochem Biophys. 2005 ; 435: 50-55.
38. Nishizuka Y. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science. 1992 ; 258: 607-614.
39. Kujubu DA, Fletcher BS, Varnum BC, Lim RW, Herschman HR TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/ cyclooxygenase homologue. J Biol Chem. 1991 ; 266 (20). 12866-12872.
40. Tong M., Ding Y., Tai HH Reciprocal regulation of cyclooxygenase-2 and 15-hydroxyprostaglandin dehydrogenase expression in A549 human lung adenocarcinoma cells. Carcinogenesis. 2006 ; 27 (11). 2170-2179.
41. Mann JR, Backlund MG, Buchanan FG, et al. Repression of prostaglandin dehydrogenase by epidermal growth factor and snail increases prostaglandin E2 and promotes cancer progression. Cancer Res. 2006 ; 66 (13). 6649-6656.
42. Olson DM, Opavsky MA, Challis JR Prostaglandin synthesis by human amnion is dependent upon extracellular calcium. Can J Physiol Pharmacol. 1983 ; 61: 1089-1092.
43. Newton AC Protein kinase C: structure, function, and regulation. J Biol Chem. 1995 ; 270 (48). 28495-28498.
44. Hirai K., Ezumi Y., Nishida E., Uchiyama T., Takayama H. Comparative study of vanadate- and phorbol ester-induced cyclo-oxygenase-2 expression in human endothelial cells. Thromb Haemost. 1999 ; 82 (5). 1545-1552.
45. Miyahara T., Katoh T., Watanabe M., et al. Involvement of mitogen-activated protein kinases and protein kinase C in cadmium-induced prostaglandin E2 production in primary mouse osteoblastic cells. Toxicology. 2004 ; 200 (2-3). 159-167.
46. Molina-Holgado E., Ortiz S., Molina-Holgado F., Guaza C. Induction of PTGS2 and PGE(2) biosynthesis by IL-1beta is mediated by PKC and mitogen-activated protein kinases in murine astrocytes. Br J Pharmacol. 2000 ; 131 (1). 152-159.
47. Sooranna SR, Engineer N., Loudon JA, Terzidou V., Bennett PR, Johnson MR The mitogen-activated protein kinase dependent expression of prostaglandin H synthase-2 and interleukin-8 messenger ribonucleic acid by myometrial cells: the differential effect of stretch and interleukin-1β. J Clin Endocrinol Metab. 2005 ; 90: 3517-3527.
48. Lo CJ MAPK regulation of prostaglandin E2 production by lipopolysaccharide-stimulated macrophages is not dependent on nuclear factor kappaB. J Surg Res. 2003 ; 113 (2). 189-194.
49. Okazaki T., Chung U., Nishishita T., et al. A redox factor protein, ref1, is involved in negative gene regulation by extracellular calcium. J Biol Chem. 1994 ; 269 (45). 27855-27862.
50. Fuchs S., Philippe J., Corvol P., Pinet F. Implication of Ref-1 in the repression of renin gene transcription by intracellular calcium. J Hypertens. 2003 ; 21 (2). 327-335.