Synthesis of ethyl (1S,2R,3S,4S,5S)-2,3-O-(isopropylidene)-4-hydroxy- bicyclo[3.1.0]hexane-carboxylate from l-ribose: A versatile chiral synthon for preparation of adenosine and P2 receptor ligands

Nucleosides, Nucleotides and Nucleic Acids

Volumn 27, Issue 3, 2008, Pages 279-291

  Joshi, Bhalchandra V ^a,c   Melman, Artem ^a   Mackman, Richard L ^b   Jacobson, Kenneth A ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b GILEAD SCIENCES   (United States)

^c NEKTAR THERAPEUTICS   (United States)

Author keywords

G protein coupled receptor; Iodination; Nucleosides; Nucleotides; Purines; Pyrimidines

Indexed keywords

ADENOSINE; CARBOXYLIC ACID DERIVATIVE; LIGAND; PURINERGIC P2 RECEPTOR; RIBOSE;

AMINO ACID SUBSTITUTION; ARTICLE; CHIRALITY; ENANTIOSELECTIVITY; IODINATION; NUCLEOTIDE METABOLISM; PROTEIN CONFORMATION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

ADENOSINE; ADENOSINE DEAMINASE; HETEROCYCLIC COMPOUNDS, 3-RING; LIGANDS; NUCLEOSIDES; NUCLEOTIDES; RECEPTORS, PURINERGIC P2; RIBOSE; STEREOISOMERISM;

EID: 38949112186     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770701845253     Document Type: Article

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