Antileukemic effect of a synthetic vitamin D3 analog, HY-11, with low potential to cause hypercalcemia

International Journal of Oncology

Volumn 32, Issue 2, 2008, Pages 387-396

  Yoon, Jin Sun ^a   Kim, Ju Young ^a   Park, Hyun Ki ^a   Kim, Eun Shil ^a   Ahn, Kwang Sung ^a   Yoon, Sung Soo ^a   Cho, Cheon Gyu ^b   Kim, Byoung Kook ^a   Lee, Young Yiul ^a,b  

^a Seoul National University College of Medicine   (South Korea)

^b Hanyang University   (South Korea)

Author keywords

Acute myelogenous leukemia; Apoptosis; BALB c leukemia model; Cell cycle; Cell line; HY 11; Vitamin D3 analog

Indexed keywords

'HY 1'; CALCITRIOL; CALCIUM; CASPASE 3; COLECALCIFEROL DERIVATIVE; COLECALCIFEROL RECEPTOR; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; HY 10; HY 11; HY 2; HY 3; HY 4; HY 5; HY 6; HY 7; HY 8; HY 9; PROTEIN P27; RETINOBLASTOMA PROTEIN; SEOCALCITOL; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; VITAMIN D DERIVATIVE;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; CALCIUM BLOOD LEVEL; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CANCER SURVIVAL; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CELL STRAIN HL 60; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INACTIVATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERCALCEMIA; IC 50; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; PARACRINE SIGNALING; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURVIVAL TIME; UPREGULATION;

EID: 38849145684     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.32.2.387     Document Type: Article

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