-
1
-
-
0032694577
-
Metabonomics': Understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data [J]
-
Nicholson LK, Lindon JC, Holmes E. 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data [J]. Xenobiotica, 1999, 29(11):1181-1189.
-
(1999)
Xenobiotica
, vol.29
, Issue.11
, pp. 1181-1189
-
-
Nicholson, L.K.1
Lindon, J.C.2
Holmes, E.3
-
2
-
-
0035796127
-
Pattern recognition methods and applications in biomedical magnetic resonance [J]
-
Lindon JC, Holmes E, Nicholson JK. Pattern recognition methods and applications in biomedical magnetic resonance [J]. Prog NMRS, 2001, 39(1):1-40
-
(2001)
Prog NMRS
, vol.39
, Issue.1
, pp. 1-40
-
-
Lindon, J.C.1
Holmes, E.2
Nicholson, J.K.3
-
3
-
-
0036463681
-
Metabonomics: A platform for studying drug toxicity and gene function [J]
-
Nicholson JK, Connelly J, Lindon JC, et al. Metabonomics: a platform for studying drug toxicity and gene function [J]. Nat Rev Drug Discov, 2002, 1(2):153-161.
-
(2002)
Nat Rev Drug Discov
, vol.1
, Issue.2
, pp. 153-161
-
-
Nicholson, J.K.1
Connelly, J.2
Lindon, J.C.3
-
4
-
-
38849111850
-
-
Chinese source.
-
Chinese source.
-
-
-
-
5
-
-
0020645974
-
High resolution proton NMR studies of vertebrate blood and plasma [J]
-
Nicholson JK, Buckingham MJ, Ssdler PJ. High resolution proton NMR studies of vertebrate blood and plasma [J]. Biochem J, 1983, 211(3):605-615.
-
(1983)
Biochem J
, vol.211
, Issue.3
, pp. 605-615
-
-
Nicholson, J.K.1
Buckingham, M.J.2
Ssdler, P.J.3
-
6
-
-
20144388102
-
Comparative metabonomics of differential hydrazine toxicity in the rat and mouse [J]
-
Bollard ME, Keun HC, Beckonert O, et al. Comparative metabonomics of differential hydrazine toxicity in the rat and mouse [J]. Toxicol Appl Pharmacol, 2005, 204(2):135-151.
-
(2005)
Toxicol Appl Pharmacol
, vol.204
, Issue.2
, pp. 135-151
-
-
Bollard, M.E.1
Keun, H.C.2
Beckonert, O.3
-
7
-
-
0034634448
-
An NMR-based metabonomic approach to investigate the biochemical consequences of genetic strain differences: Application to the C57BL10J and Alpk: ApfCD mouse [J]
-
Gavaghan CL, Holmes E, Lenz E, et al. An NMR-based metabonomic approach to investigate the biochemical consequences of genetic strain differences: application to the C57BL10J and Alpk: ApfCD mouse [J]. FEBS Lett, 2000, 484 (3):169-174.
-
(2000)
FEBS Lett
, vol.484
, Issue.3
, pp. 169-174
-
-
Gavaghan, C.L.1
Holmes, E.2
Lenz, E.3
-
8
-
-
0036174751
-
Metabolic trajectory characterisation of xenobiotic-induced hepatotoxic lesions using statistical batch processing of NMR data [J]
-
Azmi J, Griffin JL, Antti H, et al. Metabolic trajectory characterisation of xenobiotic-induced hepatotoxic lesions using statistical batch processing of NMR data [J]. Analyst, 2002, 127(2):271-276.
-
(2002)
Analyst
, vol.127
, Issue.2
, pp. 271-276
-
-
Azmi, J.1
Griffin, J.L.2
Antti, H.3
-
9
-
-
0034861361
-
Metabonomic investigations into hydrazine toxicity in the rat [J]
-
Nicholls AW, Holmes E, Lindon JC, et al. Metabonomic investigations into hydrazine toxicity in the rat [J]. Chem Res Toxicol, 2001, 14(8):975-987.
-
(2001)
Chem Res Toxicol
, vol.14
, Issue.8
, pp. 975-987
-
-
Nicholls, A.W.1
Holmes, E.2
Lindon, J.C.3
-
10
-
-
0033795182
-
Metabonomics: Evaluation of nuclear magnetic resonance (NMR) and pattern recognition technology for rapid in vivo screening of liver and kidney toxicants [J]
-
Robertson DG, Reily MD, Sigler Re, et al. Metabonomics: evaluation of nuclear magnetic resonance (NMR) and pattern recognition technology for rapid in vivo screening of liver and kidney toxicants [J]. Toxicol Sci, 2000, 57(2):326-337.
-
(2000)
Toxicol Sci
, vol.57
, Issue.2
, pp. 326-337
-
-
Robertson, D.G.1
Reily, M.D.2
Sigler, R.3
-
11
-
-
0036163759
-
Mechanisms of hepatotoxicity [J]
-
Jaeschke H, Gores GJ, Cederbaum AI, et al. Mechanisms of hepatotoxicity [J]. Toxicol Sci, 2002, 65(2):166-176.
-
(2002)
Toxicol Sci
, vol.65
, Issue.2
, pp. 166-176
-
-
Jaeschke, H.1
Gores, G.J.2
Cederbaum, A.I.3
-
12
-
-
0036435788
-
Starvation-induced posttranscriptional control of rat liver nutochondrial citrate carrier expression [J]
-
Siculella L, Sabetta S, Di Summa R, et al. Starvation-induced posttranscriptional control of rat liver nutochondrial citrate carrier expression [J]. Biochem Biophys Res Commun, 2002, 299(3):418-423.
-
(2002)
Biochem Biophys Res Commun
, vol.299
, Issue.3
, pp. 418-423
-
-
Siculella, L.1
Sabetta, S.2
Di Summa, R.3
-
13
-
-
2342499901
-
1H NMR analysis of urine in toxicity studies: Effects of reduced feeding [J]
-
1H NMR analysis of urine in toxicity studies: effects of reduced feeding [J]. Toxicology, 2001, 164(3):225-229.
-
(2001)
Toxicology
, vol.164
, Issue.3
, pp. 225-229
-
-
Sweatman, B.C.1
Manini, J.A.2
Waterfield, C.J.3
-
14
-
-
0034130232
-
Chemometric models for toxicity classification based on NMR spectra of biofluids [J]
-
Holmes E, Nicholls AW, Lindon JC, et al. Chemometric models for toxicity classification based on NMR spectra of biofluids [J]. Chem Res Toxicol, 2000, 13(6):471-478.
-
(2000)
Chem Res Toxicol
, vol.13
, Issue.6
, pp. 471-478
-
-
Holmes, E.1
Nicholls, A.W.2
Lindon, J.C.3
-
15
-
-
0035107971
-
Metabonomic classification of genetic variations in toxicological and metabolic responses using probabalistic neural networks [J]
-
Holmes E, Nicholson JK, Tranter G. Metabonomic classification of genetic variations in toxicological and metabolic responses using probabalistic neural networks [J]. Chem Res Toxicol, 2001, 14(2):182-191.
-
(2001)
Chem Res Toxicol
, vol.14
, Issue.2
, pp. 182-191
-
-
Holmes, E.1
Nicholson, J.K.2
Tranter, G.3
-
16
-
-
0034130232
-
Chemometric models for toxicity based on NMR spectra of biofluids [J]
-
Holmes E, Nicholls AW, Lindon JC, et al. Chemometric models for toxicity based on NMR spectra of biofluids [J]. Chem Res Toxicol, 2000, 13(6):471-478.
-
(2000)
Chem Res Toxicol
, vol.13
, Issue.6
, pp. 471-478
-
-
Holmes, E.1
Nicholls, A.W.2
Lindon, J.C.3
-
17
-
-
0028083271
-
Pattern recognition of the site of nephrotoxicity based on metabolic data derived from proton nuclear magnetic resonance spectra of urine [J]
-
Anthony ML, Sweatman BC, Beddll CR, et al. Pattern recognition of the site of nephrotoxicity based on metabolic data derived from proton nuclear magnetic resonance spectra of urine [J]. Mol Pharmacol, 1994, 46(1):199-211.
-
(1994)
Mol Pharmacol
, vol.46
, Issue.1
, pp. 199-211
-
-
Anthony, M.L.1
Sweatman, B.C.2
Beddll, C.R.3
-
18
-
-
0032517858
-
The identification of novel biomarkers of renal toxicity using automatic data reduction techniques and PCA of proton NMR spectra of urine [J]
-
Holmes E, Nicholson JK, Nicholls AW, et al. The identification of novel biomarkers of renal toxicity using automatic data reduction techniques and PCA of proton NMR spectra of urine [J]. Chemometrics Intel Lab Sys, 1998, 44(3): 245-255.
-
(1998)
Chemometrics Intel Lab Sys
, vol.44
, Issue.3
, pp. 245-255
-
-
Holmes, E.1
Nicholson, J.K.2
Nicholls, A.W.3
|