The KCNQ/M-current modulates arterial baroreceptor function at the sensory terminal in rats

Journal of Physiology

Volumn 586, Issue 3, 2008, Pages 795-802

  Wladyka, Cynthia L ^a   Feng, Bin ^b   Glazebrook, Patricia A ^a   Schild, John H ^b   Kunze, Diana L ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Indiana University Purdue University Indianapolis   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM CHANNEL KCNQ; POTASSIUM CHANNEL KCNQ2; POTASSIUM CHANNEL KCNQ3; POTASSIUM CHANNEL KCNQ5; RETIGABINE; UNCLASSIFIED DRUG; 10,10 BIS(4 PYRIDINYLMETHYL) 9(10H) ANTHRACENONE;

ANIMAL CELL; ANIMAL TISSUE; AORTA PRESSORECEPTOR; ARTERIAL PRESSURE; ARTICLE; CELL LABELING; CONTROLLED STUDY; GENE FUNCTION; HYPERPOLARIZATION; IMMUNOHISTOCHEMISTRY; M TYPE POTASSIUM CURRENT; MALE; NERVE CELL MEMBRANE HYPERPOLARIZATION; NERVE CELL MEMBRANE STEADY POTENTIAL; NERVE EXCITABILITY; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; ADULT; ANIMAL EXPERIMENT; AORTA ARCH; AORTA PRESSURE; ARTERIAL BARORECEPTOR; NERVE CELL EXCITABILITY; PRESSORECEPTOR; PROTEIN FUNCTION; SENSORY NERVE;

ANIMALS; ANTHRACENES; ANTICONVULSANTS; AORTA, THORACIC; CARBAMATES; KCNQ POTASSIUM CHANNELS; KCNQ2 POTASSIUM CHANNEL; KCNQ3 POTASSIUM CHANNEL; MALE; MEMBRANE POTENTIALS; NEURONS, AFFERENT; NODOSE GANGLION; PATCH-CLAMP TECHNIQUES; PHENYLENEDIAMINES; PRESSORECEPTORS; PRESYNAPTIC TERMINALS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 38849088576     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2007.145284     Document Type: Article

References (15)

1. Adams PR, Brown DA & Constanti A (1982). M-currents and other potassium currents in bullfrog sympathetic neurons. J Physiol 330, 537-572.
2. Andresen MC & Yang M (1989). Arterial baroreceptor resetting: contributions of chronic and acute processes. Clin Exp Pharmacol Physiol Suppl 15, 19-30.
3. Block BM & Jones SW (1996). Ion permeation and block of M-type and delayed rectifier potassium channels. J Gen Physiol 107, 473-488.
4. + current in a vertebrate neurone. Nature 283, 673-676.
5. H) in sensory neurons and mechanosensitive fibers. J Neurosci 24, 3335-3343.
6. Gamper N, Stockand JD & Shapiro MS (2003). Subunit-specific modulation of KCNQ potassium channels by src tyrosine kinases. J Neurosci 23, 84-95.
7. Glazebrook PA, Ramirez A, Schild JH, Shieh C-C, Doan T, Wible BA & Kunze DL (2002). Potassium channels, Kv1.1, Kv1.2 and Kv1.6, influence excitability of rat visceral sensory neurons. J Physiol 541, 467-482.
8. Holzapfel GA, Eberlein R, Wriggers P & Weizsacker HW (1996). A new axisymmetrical membrane element for anisotropic, finite strain analysis of arteries. Comm Num Meth Eng 12, 507-517.
9. Schroder RL, Jespersen T, Christophersen P, Strobaek D, Jensen BS & Olesen SP (2001). KCNQ4 channel activation by BMS-204352 and retigabine. Neuropharmacology 40, 888-898.
10. Sogaard R, Ljungstrom T, Pedersen KA, Olesen SP & Jensen BS (2001). KCNQ4 channels expressed in mammalian cells: Functional characteristics and pharmacology. Am J Physiol Cell Physiol 280, C859-C866.
11. Tatulian L, Delmas P, Abogadie FC & Brown DA (2001). Activation of expressed KCNQ potassium currents and native neuronal M-type potassium currents by the anti-convulsant drug retigabine. J Neurosci 21, 5535-5545.
12. Tinel N, Diochot S, Lauritzen I, Barhanin J, Lazdunski M & Borsotto M (2000). M-type KCNQ2-KCNQ3 potassium channels are modulated by the KCNE2 subunit. FEBS Lett 480, 137-141.
13. Wang HS, Brown BS, McKinnon D & Cohen IS (2000). Molecular basis for differential sensitivity of KCNQ and IKs channels to the cognitive enhancer XE991. Mol Pharmacol 57, 1218-1223.
14. Weizsacker HW, Lambert H & Pascale K (1983). Analysis of the passive mechanical properties of rat carotid arteries. J Biomech 16, 703-715.
15. Wladyka CL & Kunze DL (2006). KCNQ/M currents contribute to the resting membrane potential in rat nodose sensory neurons. J Physiol 575, 175-189.