Cytokinesis-block micronucleus cytome assays for the determination of genotoxicity and cytotoxicity of cecal water in rats and fecal water in humans

Cancer Epidemiology Biomarkers and Prevention

Volumn 16, Issue 12, 2007, Pages 2676-2680

  Benassi, Bianca ^a,b   LeLeu, Richard ^a   Bird, Tony ^a   Clifton, Peter ^a   Fenech, Michael ^a  

^a CSIRO   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CASEIN; CECAL WATER; FAT; TOXIC SUBSTANCE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOBLAST; CANCER RISK; COLORECTAL CANCER; CONTROLLED STUDY; CYTOKINESIS BLOCK MICRONUCLEUS CYTOME ASSAY; CYTOTOXICITY; DIET; DILUTION; FECES; GENOTOXICITY; HUMAN; HUMAN CELL; INTESTINE FLUID; MALE; MICRONUCLEUS; MICRONUCLEUS TEST; NONHUMAN; PRIORITY JOURNAL; RAT; RED MEAT;

ANIMALS; BODY WATER; CECUM; CELL LINE, TUMOR; CYTOKINESIS; DIET; FECES; HUMANS; MALE; MICRONUCLEUS TESTS; MUTAGENICITY TESTS; MUTAGENS; RATS; RATS, SPRAGUE-DAWLEY; SENSITIVITY AND SPECIFICITY;

EID: 38849087239     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-07-0488     Document Type: Article

References (25)

1. Lipkin M, Reddy B, Newmark H, Lamprecht SA. Dietary factors in human colorectal cancer. Annu Rev Nutr 1999;19:545-86.
2. Armstrong B, Doll R. Environmental factors and cancer incidence and mortality in different countries, with special reference to dietary practices. Int J Cancer 1975;15:617-31.
3. American Institute for Cancer Research/World Cancer Research Fund. Food, nutrition and the prevention of cancer: a global perspective. Washington (DC): American Institute for Cancer Research; 1997.
4. Norat T, Bingham S, Ferrari P, et al. Meat, fish, and colorectal cancer risk: the European Prospective Investigation into cancer and nutrition. J Natl Cancer Inst 2005;97:906-16.
5. Sandhu MS, White IR, McPherson K. Systematic review of the prospective cohort studies on meat consumption and colorectal cancer risk: a meta-analytical approach. Cancer Epidemiol Biomarkers Prev 2001;10:439-46.
6. Young GP, Hu Y, Le Leu RK, Nyskohus L. Dietary fibre and colorectal cancer: a model for environment-gene interactions. Mol Nutr Food Res 2005;49:571-84.
7. Giovannucci E, Willett WC. Dietary factors and risk of colon cancer. Ann Med 1994;26:443-52.
8. Howe GR, Benito E, Castelleto R, et al. Dietary intake of fiber and decreased risk of cancers of the colon and rectum: evidence from the combined analysis of 13 case-control studies. J Natl Cancer Inst 1992;84:1887-96.
9. Osswald K, Becker TW, Grimm M, Jahreis G, Pool-Zobel BL. Inter- and intra-individual variation of faecal water - genotoxicity in human colon cells. Mutat Res 2000;472:59-70.
10. de Kok TM, van Maanen JM. Evaluation of fecal mutagenicity and colorectal cancer risk. Mutat Res 2000;463:53-101.
11. Haza AI, Glinghammar B, Grandien A, Rafter J. Effect of colonic luminal components on induction of apoptosis in human colonic cell lines. Nutr Cancer 2000;36:79-89.
12. Cross AJ, Greetham HL, Pollock JR, Rowland IR, Bingham SA. Variability in fecal water genotoxicity, determined using the Comet assay, is independent of endogenous N-nitroso compound formation attributed to red meat consumption. Environ Mol Mutagen 2006;47:179-84.
13. Pfohl-Leszkowicz A, Grosse Y, Carriere V, et al. High levels of DNA adducts in human colon are associated with colorectal cancer. Cancer Res 1995;55:5611-6.
14. Hwang ES, Bowen PE. DNA damage, a biomarker of carcinogenesis: its measurement and modulation by diet and environment. Crit Rev Food Sci Nutr 2007;47:27-50.
15. Fenech M. Cytokinesis-block micronucleus assay evolves into a "cytome" assay of chromosomal instability, mitotic dysfunction and cell death. Mutat Res 2006;600:58-66.
16. Fenech M. The cytokinesis-block micronucleus cytome assay. Nat Protoc 2007;2:1084-104.
17. Report of the American Institute of Nutrition ad hoc committee on standards for nutritional studies. J Nutr 1977;107:1340-8.
18. Zhen W, Denault CM, Loviscek K, et al. The relative radiosensitivity of TK6 and WI-L2-NS lymphoblastoid cells derived from a common source is primarily determined by their p53 mutational status. Mutat Res 1995;346:85-92.
19. Umegaki K, Fenech M. Cytokinesis-block micronucleus assay in WIL2-NS cells: a sensitive system to detect chromosomal damage induced by reactive oxygen species and activated human neutrophils. Mutagenesis 2000;15:261-9.
20. Beetstra S, Thomas P, Salisbury C, Turner J, Fenech M. Folic acid deficiency increases chromosomal instability, chromosome 21 aneuploidy and sensitivity to radiation-induced micronuclei. Mutat Res 2005;578:317-26.
21. Fenech M, Chang WP, Kirsch-Volders M, et al. HUMN project: detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures. Mutat Res 2003;534:65-75.
22. Shivapurkar N, Tang ZC, Alabaster O. The effect of high-risk and low-risk diets on aberrant crypt and colonic tumor formation in Fischer-344 rats. Carcinogenesis 1992;13:887-90.
23. Bonassi S, Znaor A, Ceppi M, et al. An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans. Carcinogenesis 2007;28:625-31.
24. El-Zein RA, Schabath MB, Etzel CJ, et al. Cytokinesis-blocked micronucleus assay as a novel biomarker for lung cancer risk. Cancer Res 2006;66:6449-56.
25. Glinghammar B, Holmberg K, Rafter J. Effects of colonic lumenal components on AP-1-dependent gene transcription in cultured human colon carcinoma cells. Carcinogenesis 1999;20:969-76.