Inter- and intra-individual variation of faecal water - Genotoxicity in human colon cells

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 472, Issue 1-2, 2000, Pages 59-70

  Osswald K ^a   Becker, T W ^a   Grimm, M ^a   Jahreis, G ^a   Pool Zobel, B L ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Biomarker; Comet assay; Faecal water; Genotoxicity

Indexed keywords

BIOLOGICAL MARKER; CELL DNA; CELL ENZYME; DNA BASE; SODIUM CHLORIDE; TRYPAN BLUE;

ADULT; ANALYTIC METHOD; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DIET; DNA REPAIR; DNA STRAND BREAKAGE; FECES; FEMALE; GENOTOXICITY; HUMAN; HUMAN CELL; INTESTINE FLUID; MALE; MEMBRANE DAMAGE; OXIDATION; PRIORITY JOURNAL;

ADULT; CARCINOGENICITY TESTS; CARCINOGENS; CELL SURVIVAL; CLONE CELLS; COLON; DIET; DNA DAMAGE; FECES; FEMALE; HUMANS; LACTOBACILLUS CASEI; LIGNANS; MALE; MIDDLE AGED; MUTAGENICITY TESTS; MUTAGENS; TUMOR CELLS, CULTURED;

LONCHOCARPUS GLAUCIFOLIUS;

EID: 0034694965     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(00)00113-3     Document Type: Article

References (25)

1. Worldwide patterns of cancer mortality, 1985-1989
2. A genetic model for colorectal tumourigenesis
3. Colorectal cancer: Molecules and populations
4. Bacteria used for the production of yogurt inactivate carcinogens and prevent DNA damage in the colon of rats
5. The carbohydrate crystalean and colonic microflora modulate expression of glutathione S-transferase subunits in colon of rats
6. Lactobacillus- and bifidobacterium-mediated antigenotoxicity in colon cells of rats: Prevention of carcinogen-induced damage in vivo and elucidation of involved mechanisms
7. The effect of a shift from a mixed diet to a lacto-vegetarian diet on human urinary and fecal mutagenic activity
8. Genotoxic activity in human faecal water and the role of bile acids: A study using the alkaline comet-assay
9. A simple technique for quantitation of low levels of DNA damage in individual cells
10. Diets high in fat and meat but low in fiber increase the genotoxic potential of faecal water
11. Einfluss einer erhohten phosphatzufuhr bei jungen frauen auf parameter des knochenstoffwechsels und der nierenfunktion sowie auf mengen- und spurenelemente im serum
12. Antigenotoxic properties of lactic acid bacteria in the Salmonella typhimurium mutagenicity assay
13. Isoflavonoids and lignans have different potentials to modulate oxidative genetic damage in human colon cells
14. Cellular toxicity of faecal water depends on diet
15. The human colon carcinoma cell lines HT29 and Caco-2: Two in vitro models for the study of intestinal differentiation
16. Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate
17. Consumption of vegetables reduces genetic damage in humans: First results of an intervention trial with carotenoid-rich foods
18. Analysis of DNA strand breaks, oxidised bases and glutathione S-transferase P1 in human colon cells
19. Anthocyanins are potent antioxidants in vitro but do not reduce oxidative DNA damage within human colon cells
20. Diet, gut microflora and carcinogenesis
21. Diet and faecal genotoxicity
22. Mutagens in human faeces and cancer of the large bowel
23. Diet-induced increase of colonic bile acids stimulates lytic activity of faecal water and proliferation of colonic cells