Synthesis and cytotoxicity evaluation of 22,23-oxygenated stigmastane derivatives

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 3, 2008, Pages 1460-1473

  Misharin, Alexander Yu ^a   Mehtiev, Arif R ^a   Morozevich, Galina E ^a   Tkachev, Yaroslav V ^b   Timofeev, Vladimir P ^b  

^a INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

^b ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

Author keywords

Cytotoxicity; MTT assay; Sterols; Stigmastane

Indexed keywords

22,23 DIHYDROXYSTIGMAST 4 EN 3 ONE; 22,23 DIHYDROXYSTIGMAST 4 EN 3,6 DIONE; 22,23 ISOPROPYLIDENEDIOXYSTIGMAST 4 EN 3,6 DIONE; 22,23 OXIDOSTIGMAST 4 EN 3 ONE; 22,23 OXIDOSTIGMAST 4 EN 3,6 DIONE; 3 BETA 22,23 TRIACETOXY 5 ALPHA 6 ALPHA OXIDOSTIGMASTANE; 3 BETA 22,23 TRIHYDROXY 5 ALPHA 6 ALPHA OXIDOSTIGMASTANE; 3 BETA 22,23 TRIHYDROXYSITOST 5 ENE; 3 BETA 22,23 TRIHYDROXYSTIG MAST 5 EN 7 ONE; 3 BETA 22,23 TRIHYDROXYSTIGMAST 5 ENE; 3 BETA 5 ALPHA 6 BETA 22,23 PENTAHYDROXYSTIGMASTANE; 3 BETA 7 ALPHA DIHYDROXY 22,23 OXIDOSTIGMAST 5 ENE; 3 BETA 7 BETA DIHYDROXY 22,23 OXIDOSTIGMAST 5 ENE; 3 BETA HYDROXY 22,23 OXIDOSTIGMAST 5 EN 7 ONE; 3 BETA HYDROXY 22,23 OXIDOSTIGMAST 5 ENE; NITROBLUE TETRAZOLIUM; STEROL DERIVATIVE; STIGMASTANE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CELL STRAIN HEPG2; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NITROBLUE TETRAZOLIUM TEST;

CELL LINE, TUMOR; CELL SURVIVAL; CHOLESTENONES; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; OXYGEN; PROTONS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 38849085288     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.10.056     Document Type: Article

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