Potent heteroarylpiperidine and carboxyphenylpiperidine 1-alkyl-cyclopentane carboxamide CCR2 antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 3, 2008, Pages 994-998

  Pasternak, Alexander ^a   Goble, Stephen D ^a   Vicario, Pasquale P ^a   Di Salvo, Jerry ^a   Ayala, Julia M ^a   Struthers, Mary ^a   DeMartino, Julie A ^a   Mills, Sander G ^a   Yang, Lihu ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Antagonist; CCR2; Chemokine

Indexed keywords

4 (CARBOXYPHENYL)PIPERIDINE; CHEMOKINE RECEPTOR ANTAGONIST; CHEMOKINE RECEPTOR CCR2 ANTAGONIST; PIPERIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; BINDING AFFINITY; BINDING ASSAY; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; EMBRYO; HUMAN; HUMAN CELL;

ANIMALS; HUMANS; MOLECULAR STRUCTURE; PIPERIDINES; POTASSIUM CHANNEL BLOCKERS; RATS; RECEPTORS, CCR2; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 38749132851     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.12.029     Document Type: Article

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