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Volumn 308, Issue 1-2, 2008, Pages 161-168

RNA interference (RNAi)-mediated vascular endothelial growth factor-C (VEGF-C) reduction interferes with lymphangiogenesis and enhances Epirubicin sensitivity of breast cancer cells

Author keywords

Breastcancer; Epirubicin; Human lymphatic endothelial cells (HLECs); RNA interference (RNAi); Vascular endothelial growth factor C (VEGF C)

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; EPIRUBICIN; PROTEIN BAX; PROTEIN BCL 2; SMALL INTERFERING RNA; VASCULOTROPIN C;

EID: 38649115326     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-007-9624-1     Document Type: Article
Times cited : (32)

References (30)
  • 2
    • 23944466427 scopus 로고    scopus 로고
    • A pooled analysis of bone marrow micro-metastasis in breast cancer
    • Braun S, Vogl FD, Naume B et al (2005) A pooled analysis of bone marrow micro-metastasis in breast cancer. N Engl J Med 353:793-802
    • (2005) N Engl J Med , vol.353 , pp. 793-802
    • Braun, S.1    Vogl, F.D.2    Naume, B.3
  • 3
    • 0035060628 scopus 로고    scopus 로고
    • Pathological validation and significance of micrometastasis in sentinel nodes in primary breast cancer
    • Rampaul RS, Miremad A, Pinder SE et al (2001) Pathological validation and significance of micrometastasis in sentinel nodes in primary breast cancer. Breast Cancer Res 3:113-116
    • (2001) Breast Cancer Res , vol.3 , pp. 113-116
    • Rampaul, R.S.1    Miremad, A.2    Pinder, S.E.3
  • 4
    • 0037310399 scopus 로고    scopus 로고
    • Differential in vivo and in vitro expression of vascular endothelial growth factor (VEGF)-C and VEGF-D in tumors and its relationship to lymphatic metastasis in immunocompetent rats
    • Krishnan J, Kirkin V, Steffen A et al (2003) Differential in vivo and in vitro expression of vascular endothelial growth factor (VEGF)-C and VEGF-D in tumors and its relationship to lymphatic metastasis in immunocompetent rats. Cancer Res 63:713-722
    • (2003) Cancer Res , vol.63 , pp. 713-722
    • Krishnan, J.1    Kirkin, V.2    Steffen, A.3
  • 5
    • 0036733564 scopus 로고    scopus 로고
    • Tumor-associated macrophages express lymphatic endothelial growth factors and are related to peritumoral lymphangiogenesis
    • Schoppmann SF, Birner P, Stöckl J et al (2002) Tumor-associated macrophages express lymphatic endothelial growth factors and are related to peritumoral lymphangiogenesis. Am J Pathol 161:947-956
    • (2002) Am J Pathol , vol.161 , pp. 947-956
    • Schoppmann, S.F.1    Birner, P.2    Stöckl, J.3
  • 6
    • 14244269759 scopus 로고    scopus 로고
    • The lymphangiogenesis vascular endothelial growth factors VEGF-C and -D are ligands for the integrin alpha9beta1
    • Vlahakis NE, Young BA, Atakilit A et al (2005) The lymphangiogenesis vascular endothelial growth factors VEGF-C and -D are ligands for the integrin alpha9beta1. J Biol Chem 280:4544-4552
    • (2005) J Biol Chem , vol.280 , pp. 4544-4552
    • Vlahakis, N.E.1    Young, B.A.2    Atakilit, A.3
  • 7
    • 0030973506 scopus 로고    scopus 로고
    • Hyperplasia of lymphatic vessels in VEGF-C transgenic mice
    • Jeltsch M, Kaipainen A, Joukov V et al (1997) Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. Science 276:1423-1425
    • (1997) Science , vol.276 , pp. 1423-1425
    • Jeltsch, M.1    Kaipainen, A.2    Joukov, V.3
  • 8
    • 0035266283 scopus 로고    scopus 로고
    • Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth
    • Karpanen T, Egeblad M, Karkkainen M et al (2001) Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth. Cancer Res 61:1786-1790
    • (2001) Cancer Res , vol.61 , pp. 1786-1790
    • Karpanen, T.1    Egeblad, M.2    Karkkainen, M.3
  • 9
    • 34548028000 scopus 로고    scopus 로고
    • VEGF-C, VEGFR-3, and COX-2 enhances growth and metastasis of human cervical carcinoma cell lines in vitro
    • Shi X, Chen G, Xing H et al (2007) VEGF-C, VEGFR-3, and COX-2 enhances growth and metastasis of human cervical carcinoma cell lines in vitro. Oncol Rep 18:241-247
    • (2007) Oncol Rep , vol.18 , pp. 241-247
    • Shi, X.1    Chen, G.2    Xing, H.3
  • 10
    • 34248190166 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-C secreted by pancreatic cancer cell line promotes lymphatic endothelial cell migration in an in vitro model of tumor lymphangiogenesis
    • Ochi N, Matsuo Y, Sawai H et al (2007) Vascular endothelial growth factor-C secreted by pancreatic cancer cell line promotes lymphatic endothelial cell migration in an in vitro model of tumor lymphangiogenesis. Pancreas 34:444-451
    • (2007) Pancreas , vol.34 , pp. 444-451
    • Ochi, N.1    Matsuo, Y.2    Sawai, H.3
  • 11
    • 33747589866 scopus 로고    scopus 로고
    • Hypoxia inducible factor-1alpha correlate with VEGF-C expression and lymphangiogenesis in breast cancer
    • Schoppmann SF, Fenzl A, Schindl M et al (2006) Hypoxia inducible factor-1alpha correlate with VEGF-C expression and lymphangiogenesis in breast cancer. Breast Cancer Res Treat 99:135-141
    • (2006) Breast Cancer Res Treat , vol.99 , pp. 135-141
    • Schoppmann, S.F.1    Fenzl, A.2    Schindl, M.3
  • 12
    • 0037085765 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF)-C signaling through FLT-4 (VEGFR-) mediates leukemic cell proliferation, survival, and resistance to chemotherapy
    • Dias S, Choy M, Alitalo K et al (2002) Vascular endothelial growth factor (VEGF)-C signaling through FLT-4 (VEGFR-) mediates leukemic cell proliferation, survival, and resistance to chemotherapy. Blood 99:2179-2184
    • (2002) Blood , vol.99 , pp. 2179-2184
    • Dias, S.1    Choy, M.2    Alitalo, K.3
  • 13
    • 5344225275 scopus 로고    scopus 로고
    • Preoperative chemotherapy of continuous infusion of 5-Fluorouracil, Epirubicin or Pirarubicin and cyclophosphamine in operable primary breast cancer
    • Li JF, Ou YT, Wang TF et al (2004) Preoperative chemotherapy of continuous infusion of 5-Fluorouracil, Epirubicin or Pirarubicin and cyclophosphamine in operable primary breast cancer. Chinese Journal of Cancer Res 16:197-202
    • (2004) Chinese Journal of Cancer Res , vol.16 , pp. 197-202
    • Li, J.F.1    Ou, Y.T.2    Wang, T.F.3
  • 14
    • 0034737747 scopus 로고    scopus 로고
    • Genetic requirements for inheritance of RNAi in C. elegans
    • Grishok A, Tabara H, Mello CC (2000) Genetic requirements for inheritance of RNAi in C. elegans. Science 287:2494-2497
    • (2000) Science , vol.287 , pp. 2494-2497
    • Grishok, A.1    Tabara, H.2    Mello, C.C.3
  • 15
    • 0035694237 scopus 로고    scopus 로고
    • Identification of essential genes in cultured mammalian cells using small interfering RNAs
    • Harborth J, Elbashir SM, Bechert K et al (2001) Identification of essential genes in cultured mammalian cells using small interfering RNAs. J Cell Sci 114:4557-4565
    • (2001) J Cell Sci , vol.114 , pp. 4557-4565
    • Harborth, J.1    Elbashir, S.M.2    Bechert, K.3
  • 16
    • 0037117550 scopus 로고    scopus 로고
    • A DNA vector based RNAi technology to suppress gene expression in mammalian cells
    • Sui G, Soohoo C, Affar el B et al (2002) A DNA vector based RNAi technology to suppress gene expression in mammalian cells. Proc Natl Acad Sci USA 99:5515-5520
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 5515-5520
    • Sui, G.1    Soohoo, C.2    Affar el, B.3
  • 17
    • 0037197914 scopus 로고    scopus 로고
    • RNA interfering by expression of short interfering RNAs and hairpin RNAs in mammalian cells
    • Yu JY, DeRuiter SL, Turner DL (2002) RNA interfering by expression of short interfering RNAs and hairpin RNAs in mammalian cells. Proc Natl Acad Sci USA 99:6047-6052
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 6047-6052
    • Yu, J.Y.1    DeRuiter, S.L.2    Turner, D.L.3
  • 18
    • 27344431724 scopus 로고    scopus 로고
    • Insulin-like growth factors 1 and 2 induce lymphangiogenesis in vivo
    • Bjorndahl M, Cao R, Nissen LJ et al (2005) Insulin-like growth factors 1 and 2 induce lymphangiogenesis in vivo. Proc Natl Acad Sci USA 102:15593-15598
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15593-15598
    • Bjorndahl, M.1    Cao, R.2    Nissen, L.J.3
  • 19
    • 34247881817 scopus 로고    scopus 로고
    • Bcl-2-specific siRNAs restore Gemcitabine sensitivity in human pancreatic cancer cells
    • Okamoto K, Ocker M, Neureiter D et al (2007) Bcl-2-specific siRNAs restore Gemcitabine sensitivity in human pancreatic cancer cells. Cell Mol Med 11:349- 361
    • (2007) Cell Mol Med , vol.11
    • Okamoto, K.1    Ocker, M.2    Neureiter, D.3
  • 20
    • 12444343144 scopus 로고    scopus 로고
    • Complete and specific inhibition of adult lymphatic regeneration by a novel VEGFR-3 neutralizing antibody
    • Pytowski B, Goldman J, Persaud K et al (2005) Complete and specific inhibition of adult lymphatic regeneration by a novel VEGFR-3 neutralizing antibody. J Natl Cancer Inst 97:14-21
    • (2005) J Natl Cancer Inst , vol.97 , pp. 14-21
    • Pytowski, B.1    Goldman, J.2    Persaud, K.3
  • 21
    • 0037024472 scopus 로고    scopus 로고
    • Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor-3 signaling
    • HeY, Kozaki K, Karpanen T et al (2002) Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor-3 signaling. J Natl Cancer Inst 94:819-825
    • (2002) J Natl Cancer Inst , vol.94 , pp. 819-825
    • He, Y.1    Kozaki, K.2    Karpanen, T.3
  • 22
    • 24144445346 scopus 로고    scopus 로고
    • Comparison of the suppression effects of antisense oligonucleotides and siRNA directed against the same targets in mammalian cells
    • Miyagishi M, Hayashi M, Taira K (2003) Comparison of the suppression effects of antisense oligonucleotides and siRNA directed against the same targets in mammalian cells. Antisense Nucleic Acid Drug Dev 13:1-7
    • (2003) Antisense Nucleic Acid Drug Dev , vol.13 , pp. 1-7
    • Miyagishi, M.1    Hayashi, M.2    Taira, K.3
  • 23
    • 0037022382 scopus 로고    scopus 로고
    • Stable suppression of gene expression by RNAi in mammalian cells
    • Paddison PJ, Caudy AA, Hannon GJ (2002) Stable suppression of gene expression by RNAi in mammalian cells. Proc Natl Acad Sci USA 99:1443-1448
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 1443-1448
    • Paddison, P.J.1    Caudy, A.A.2    Hannon, G.J.3
  • 24
    • 0037140120 scopus 로고    scopus 로고
    • VEGF-C induced lymphangiogenesis is associated with lymph node metastasis in orthotopic MCF-7 tumors
    • Mattila MM, Ruohola JK, Karpanen T et al (2002) VEGF-C induced lymphangiogenesis is associated with lymph node metastasis in orthotopic MCF-7 tumors. Int J Cancer 98:946-951
    • (2002) Int J Cancer , vol.98 , pp. 946-951
    • Mattila, M.M.1    Ruohola, J.K.2    Karpanen, T.3
  • 25
    • 33846180704 scopus 로고    scopus 로고
    • Lymphatic endothelial cells, tumor lymphangiogenesis and metastasis: New insights into intratumoral and peritumoral lymphatics
    • Ji RC (2006) Lymphatic endothelial cells, tumor lymphangiogenesis and metastasis: New insights into intratumoral and peritumoral lymphatics. Cancer Metastasis Rev 25:677-694
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 677-694
    • Ji, R.C.1
  • 26
    • 35448946476 scopus 로고    scopus 로고
    • Lymphatic endothelial cells, inflammatory lymphangiogenesis, and prospective players
    • Ji RC (2007) Lymphatic endothelial cells, inflammatory lymphangiogenesis, and prospective players. Curr Med Chem 14:2359-2368
    • (2007) Curr Med Chem , vol.14 , pp. 2359-2368
    • Ji, R.C.1
  • 27
    • 0037302501 scopus 로고    scopus 로고
    • Combined epirubicin and vinorelbine as first-line therapy in metastatic breast cancer: A pilot study performed by the Danish Breast Cancer Cooperative Group
    • Ejlertsen B, Hojris I, Hansen S et al (2003) Combined epirubicin and vinorelbine as first-line therapy in metastatic breast cancer: A pilot study performed by the Danish Breast Cancer Cooperative Group. Breast 12:42-50
    • (2003) Breast , vol.12 , pp. 42-50
    • Ejlertsen, B.1    Hojris, I.2    Hansen, S.3
  • 28
    • 33847149631 scopus 로고    scopus 로고
    • Individually tailored toxicity-based 5-fluorouracil, epirubicin and cyclophosphamide (FEC) therapy of metastatic breast cancer
    • Lindman H, Astrom G, Ahlgren J et al (2007) Individually tailored toxicity-based 5-fluorouracil, epirubicin and cyclophosphamide (FEC) therapy of metastatic breast cancer. Acta Oncol 46:165-171
    • (2007) Acta Oncol , vol.46 , pp. 165-171
    • Lindman, H.1    Astrom, G.2    Ahlgren, J.3
  • 29
    • 11144220793 scopus 로고    scopus 로고
    • Relative Bcl-2 indepenence of drug-induced cytotoxicity and resistance in 518A2 melanoma cells
    • Benimetskaya L, Lai JC, Khvorova A et al (2004) Relative Bcl-2 indepenence of drug-induced cytotoxicity and resistance in 518A2 melanoma cells. Clin Cancer Res 10:8371-8379
    • (2004) Clin Cancer Res , vol.10 , pp. 8371-8379
    • Benimetskaya, L.1    Lai, J.C.2    Khvorova, A.3
  • 30
    • 20444456293 scopus 로고    scopus 로고
    • Bcl-2 acts in a proangiogenic signaling pathway through nuclear factor-kappaB and CXC chemokines
    • Karl E, Warner K, Zeitlin B et al (2005) Bcl-2 acts in a proangiogenic signaling pathway through nuclear factor-kappaB and CXC chemokines. Cancer Res 65:5063-5069
    • (2005) Cancer Res , vol.65 , pp. 5063-5069
    • Karl, E.1    Warner, K.2    Zeitlin, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.