-
1
-
-
0037024472
-
Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling
-
[comment]
-
He Y, Kozaki K, Karpanen T, Koshikawa K, Yla-Herttuala S, Takahashi T, et al. Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling [comment]. J Natl Cancer Inst. 2002;94:819-25.
-
(2002)
J. Natl. Cancer Inst.
, vol.94
, pp. 819-825
-
-
He, Y.1
Kozaki, K.2
Karpanen, T.3
Koshikawa, K.4
Yla-Herttuala, S.5
Takahashi, T.6
-
2
-
-
0036310316
-
The role of tumor lymphangiogenesis in metastatic spread
-
Stacker SA, Baldwin ME, Achen MG. The role of tumor lymphangiogenesis in metastatic spread. FASEB J. 2002;16:922-34.
-
(2002)
FASEB J.
, vol.16
, pp. 922-934
-
-
Stacker, S.A.1
Baldwin, M.E.2
Achen, M.G.3
-
3
-
-
0035940071
-
The physiology of the lymphatic system
-
Swartz MA. The physiology of the lymphatic system. Adv Drug Deliv Rev. 2001;50:3-20.
-
(2001)
Adv. Drug Deliv. Rev.
, vol.50
, pp. 3-20
-
-
Swartz, M.A.1
-
4
-
-
0030118083
-
A novel vascular endothelial growth factor VEGF-C is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases
-
[erratum appears in EMBO J. 1996 Apr 1;15(7):1751; PMID: 8612600]
-
Joukov V, Pajusola K, Kaipainen A, Chilov D, Lahtinen I, Kukk E, et al. A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases.[erratum appears in EMBO J. 1996 Apr 1;15(7):1751; PMID: 8612600]. EMBO J. 1996;15:290-98.
-
(1996)
EMBO J.
, vol.15
, pp. 290-298
-
-
Joukov, V.1
Pajusola, K.2
Kaipainen, A.3
Chilov, D.4
Lahtinen, I.5
Kukk, E.6
-
5
-
-
0029962242
-
Vascular endothelial growth factor-related protein: A ligand and specific activator of the tyrosine kinase receptor Flt4
-
Lee J, Gray A, Yuan J, Luoh SM, Avraham H, Wood WI. Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt4. Proc Natl Acad Sci USA. 1996;93:1988-92.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 1988-1992
-
-
Lee, J.1
Gray, A.2
Yuan, J.3
Luoh, S.M.4
Avraham, H.5
Wood, W.I.6
-
6
-
-
0031011529
-
Proteolytic processing regulates receptor specificity and activity of VEGF-C
-
Joukov V, Sorsa T, Kumar V, Jeltsch M, Claesson-Welsh L, Cao Y, et al. Proteolytic processing regulates receptor specificity and activity of VEGF-C. EMBO J. 1997;16:3898-911.
-
(1997)
EMBO J.
, vol.16
, pp. 3898-3911
-
-
Joukov, V.1
Sorsa, T.2
Kumar, V.3
Jeltsch, M.4
Claesson-Welsh, L.5
Cao, Y.6
-
7
-
-
0028938746
-
Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development
-
Kaipainen A, Korhonen J, Mustonen T, van Hinsbergh VW, Fang GH, Dumont D, Breitman M, Alitalo K. Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development. Proc Natl Acad Sci USA. 1995;92:3566-70.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 3566-3570
-
-
Kaipainen, A.1
Korhonen, J.2
Mustonen, T.3
van Hinsbergh, V.W.4
Fang, G.H.5
Dumont, D.6
Breitman, M.7
Alitalo, K.8
-
8
-
-
17744390184
-
Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis
-
Mandriota SJ, Jussila L, Jeltsch M, Compagni A, Baetens D, Prevo R, et al. Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis. EMBO J. 2001;20:672-682.
-
(2001)
EMBO J.
, vol.20
, pp. 672-682
-
-
Mandriota, S.J.1
Jussila, L.2
Jeltsch, M.3
Compagni, A.4
Baetens, D.5
Prevo, R.6
-
9
-
-
0035122537
-
Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis
-
Skobe M, Hawighorst T, Jackson DG, Prevo R, Janes L, Velasco P, et al. Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis. Nat Med. 2001;7:192-8.
-
(2001)
Nat. Med.
, vol.7
, pp. 192-198
-
-
Skobe, M.1
Hawighorst, T.2
Jackson, D.G.3
Prevo, R.4
Janes, L.5
Velasco, P.6
-
10
-
-
0035266283
-
Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth
-
Karpanen T, Egeblad M, Karkkainen MJ, Kubo H, Yla-Herttuala S, Jaattela M, Alitalo K. Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth. Cancer Res. 2001;61:1786-90.
-
(2001)
Cancer Res.
, vol.61
, pp. 1786-1790
-
-
Karpanen, T.1
Egeblad, M.2
Karkkainen, M.J.3
Kubo, H.4
Yla-Herttuala, S.5
Jaattela, M.6
Alitalo, K.7
-
11
-
-
0036673666
-
Lymphangiogenesis and cancer metastasis
-
Stacker SA, Achen MG, Jussila L, Baldwin ME, Alitalo K. Lymphangiogenesis and cancer metastasis. Nat Rev Cancer 2002;2:573-83.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 573-583
-
-
Stacker, S.A.1
Achen, M.G.2
Jussila, L.3
Baldwin, M.E.4
Alitalo, K.5
-
12
-
-
0242624291
-
Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3
-
Makinen T, Veikkola T, Mustjoki S, Karpanen T, Catimel B, Nice EC, et al. Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3. EMBO J. 2001; 20:4762-73.
-
(2001)
EMBO J.
, vol.20
, pp. 4762-4773
-
-
Makinen, T.1
Veikkola, T.2
Mustjoki, S.3
Karpanen, T.4
Catimel, B.5
Nice, E.C.6
-
13
-
-
0035122695
-
Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3
-
Makinen T, Jussila L, Veikkola T, Karpanen T, Kettunen MI, Pulkkanen KJ, et al. Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3. Nat Med. 2001;7:199-205.
-
(2001)
Nat. Med.
, vol.7
, pp. 199-205
-
-
Makinen, T.1
Jussila, L.2
Veikkola, T.3
Karpanen, T.4
Kettunen, M.I.5
Pulkkanen, K.J.6
-
14
-
-
0037172970
-
Blockade of vascular endothelial growth factor receptor-3 signaling inhibits fibroblast growth factor-2-induced lymphangiogenesis in mouse cornea
-
Kubo H, Cao R, Brakenhielm E, Makinen T, Cao Y, Alitalo K. Blockade of vascular endothelial growth factor receptor-3 signaling inhibits fibroblast growth factor-2-induced lymphangiogenesis in mouse cornea. Proc Natl Acad Sci USA. 2002;99:8868-73.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 8868-8873
-
-
Kubo, H.1
Cao, R.2
Brakenhielm, E.3
Makinen, T.4
Cao, Y.5
Alitalo, K.6
-
15
-
-
18544393909
-
Involvement of vascular endothelial growth factor receptor-3 in maintenance of integrity of endothelial cell lining during tumor angiogenesis
-
Kubo H, Fujiwara T, Jussila L, Hashi H, Ogawa M, Shimizu K, et al. Involvement of vascular endothelial growth factor receptor-3 in maintenance of integrity of endothelial cell lining during tumor angiogenesis. Blood 2000;96:546-53.
-
(2000)
Blood
, vol.96
, pp. 546-553
-
-
Kubo, H.1
Fujiwara, T.2
Jussila, L.3
Hashi, H.4
Ogawa, M.5
Shimizu, K.6
-
16
-
-
3042587472
-
Involvement of the VEGF receptor 3 in tubular morphogenesis demonstrated with a human anti-human VEGFR-3 monoclonal antibody that antagonizes receptor activation by VEGF-C
-
Persaud K, Tille JC, Liu M, Zhu Z, Jimenez X, Pereira DS, et al. Involvement of the VEGF receptor 3 in tubular morphogenesis demonstrated with a human anti-human VEGFR-3 monoclonal antibody that antagonizes receptor activation by VEGF-C. J Cell Sci. 2004;117(Pt 13):2745-56.
-
(2004)
J. Cell Sci.
, vol.117
, Issue.PART 13
, pp. 2745-2756
-
-
Persaud, K.1
Tille, J.C.2
Liu, M.3
Zhu, Z.4
Jimenez, X.5
Pereira, D.S.6
-
17
-
-
0242609820
-
Lymphangiogenesis in a mouse tail
-
ASME / Bioengineering Division Snowbird, UT: ASME; 2001
-
Boardman KC, Swartz MA. Lymphangiogenesis in a mouse tail. In: ASME / Bioengineering Division; 2001; Snowbird, UT: ASME; 2001.
-
(2001)
-
-
Boardman, K.C.1
Swartz, M.A.2
-
18
-
-
0037453703
-
Interstitial flow as a guide for lymphangiogenesis
-
Boardman KC, Swartz MA. Interstitial flow as a guide for lymphangiogenesis. Circ Res. 2003;92:801-8.
-
(2003)
Circ. Res.
, vol.92
, pp. 801-808
-
-
Boardman, K.C.1
Swartz, M.A.2
-
19
-
-
0025011056
-
The kit ligand: A cell surface molecule altered in steel mutant fibroblasts
-
Flanagan JG, Leder P. The kit ligand: a cell surface molecule altered in steel mutant fibroblasts. Cell 1990;63:185-194.
-
(1990)
Cell
, vol.63
, pp. 185-194
-
-
Flanagan, J.G.1
Leder, P.2
-
20
-
-
0028336966
-
Heparin modulates the interaction of VEGF165 with soluble and cell associated flk-1 receptors
-
Tessler S, Rockwell P, Hicklin D, Cohen T, Levi BZ, Witte L, et al. Heparin modulates the interaction of VEGF165 with soluble and cell associated flk-1 receptors. J Biol Chem. 1994;269:12456-61.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 12456-12461
-
-
Tessler, S.1
Rockwell, P.2
Hicklin, D.3
Cohen, T.4
Levi, B.Z.5
Witte, L.6
-
22
-
-
0026055091
-
Murine endothelioma cell lines transformed by polyoma middle T oncogene as target for and producers of cytokines
-
Bussolino F, De Rossi M, Sica A, Colotta F, Wang JM, Bocchietto E, et al. Murine endothelioma cell lines transformed by polyoma middle T oncogene as target for and producers of cytokines. J Immunol. 1991;147:2122-9.
-
(1991)
J. Immunol.
, vol.147
, pp. 2122-2129
-
-
Bussolino, F.1
De Rossi, M.2
Sica, A.3
Colotta, F.4
Wang, J.M.5
Bocchietto, E.6
-
23
-
-
0030051265
-
Transport in lymphatic capillaries: I. Macroscopic measurment using residence time distribution analysis
-
Swartz MA, Berk DA, Jain RK. Transport in lymphatic capillaries: I. Macroscopic measurment using residence time distribution analysis. Am J Physiol. 1996;270:H324-329.
-
(1996)
Am. J. Physiol.
, vol.270
-
-
Swartz, M.A.1
Berk, D.A.2
Jain, R.K.3
-
24
-
-
0033593793
-
LYVE-1 a new homologue of the CD44 glycoprotein is a lymph-specific receptor for hyaluronan
-
Banerji S, Ni J, Wang SX, Clasper S, Su J, Tammi R, et al. LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan. J Cell Biol. 1999;144:789-801.
-
(1999)
J. Cell Biol.
, vol.144
, pp. 789-801
-
-
Banerji, S.1
Ni, J.2
Wang, S.X.3
Clasper, S.4
Su, J.5
Tammi, R.6
-
25
-
-
0036279804
-
Clinical development of angiogenesis inhibitors to vascular endothelial growth factor and its receptors as cancer therapeutics
-
Review
-
Zhu Z, Bohlen P, Witte L. Clinical development of angiogenesis inhibitors to vascular endothelial growth factor and its receptors as cancer therapeutics. Curr Cancer Drug Targets 2002;2:135-56. Review.
-
(2002)
Curr. Cancer Drug Targets
, vol.2
, pp. 135-156
-
-
Zhu, Z.1
Bohlen, P.2
Witte, L.3
-
26
-
-
0030058931
-
Phenotype of normal cutaneous microvasculature. Immumoelectron microscopic observations with emphasis on the differences between blood vessels and lymphatics
-
Erhard H, Rietveld FJ, Brocker EB, de Waal RM, Ruiter DJ. Phenotype of normal cutaneous microvasculature. Immumoelectron microscopic observations with emphasis on the differences between blood vessels and lymphatics. J Invest Dermatol. 1996;106:135- 40.
-
(1996)
J. Invest. Dermatol.
, vol.106
, pp. 35-40
-
-
Erhard, H.1
Rietveld, F.J.2
Brocker, E.B.3
de Waal, R.M.4
Ruiter, D.J.5
-
27
-
-
0030973506
-
Hyperplasia of lymphatic vessels in VEGF-C transgenic mice
-
Jeltsch M, Kaipainen A, Joukov V, Meng X, Lakso M, Rauvala H, et al. Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. Science 1997;276:1423-5.
-
(1997)
Science
, vol.276
, pp. 1423-1425
-
-
Jeltsch, M.1
Kaipainen, A.2
Joukov, V.3
Meng, X.4
Lakso, M.5
Rauvala, H.6
-
28
-
-
17744396472
-
Signaling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice
-
Veikkola T. Signaling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice. EMBO J. 2001;20: 1223-31.
-
(2001)
EMBO J.
, vol.20
, pp. 1223-1231
-
-
Veikkola, T.1
-
29
-
-
0037036136
-
Lymphatic metastasis in the absence of functional intratumor lymphatics
-
Padera TP, Kadambi A, di Tomaso E, Carreira CM, Brown EB, Boucher Y, et al. Lymphatic metastasis in the absence of functional intratumor lymphatics. Science 2002;296:1883-6.
-
(2002)
Science
, vol.296
, pp. 1883-1886
-
-
Padera, T.P.1
Kadambi, A.2
di Tomaso, E.3
Carreira, C.M.4
Brown, E.B.5
Boucher, Y.6
-
30
-
-
0037120009
-
Lymphangiogenetic gene theraphy with minimal blood vascular side effects
-
Saaristo A, Veikkola T, Tammela T, Enholm B, Karkkainen MJ, Pajusola K, et al. Lymphangiogenetic gene theraphy with minimal blood vascular side effects. J Exp Med. 2002;196:719-30.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 719-730
-
-
Saaristo, A.1
Veikkola, T.2
Tammela, T.3
Enholm, B.4
Karkkainen, M.J.5
Pajusola, K.6
-
31
-
-
0037373489
-
VEGF-C gene theraphy augments postnatal lymphangiogenesis and ameliorates secondary lymphedema
-
Yoon YS, Murayama T, Gravereaux E, Tkebuchava T, Silver M, Curry C, et al. VEGF-C gene theraphy augments postnatal lymphangiogenesis and ameliorates secondary lymphedema. J Clin Invest. 2003;111:717-25.
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 717-725
-
-
Yoon, Y.S.1
Murayama, T.2
Gravereaux, E.3
Tkebuchava, T.4
Silver, M.5
Curry, C.6
-
32
-
-
0035970622
-
Adenoviral expression of vascular endothelial growth factor-C induces lymphangiogenesis in the skin
-
Enholm B, Karpanen T, Jeltsch M, Kubo H, Stenback F, Prevo R, et al. Adenoviral expression of vascular endothelial growth factor-C induces lymphangiogenesis in the skin. Circ Res. 2001;88:623-9.
-
(2001)
Circ. Res.
, vol.88
, pp. 623-629
-
-
Enholm, B.1
Karpanen, T.2
Jeltsch, M.3
Kubo, H.4
Stenback, F.5
Prevo, R.6
|