Cellular localization of Nicastrin affects amyloid β species production

FEBS Letters

Volumn 582, Issue 3, 2008, Pages 427-433

  Morais, Vanessa A ^a,b   Leight, Susan ^b   Pijak, Donald S ^b   Lee, Virginia M Y ^b   Costa, Júlia ^a,c  

^a INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLÓGICA   (Portugal)

Author keywords

Secretase complex; A production; Alzheimer's disease; Nicastrin; Protein trafficking

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; GAMMA SECRETASE; NICASTRIN;

ANIMAL CELL; ARTICLE; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; TRANS GOLGI NETWORK;

AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; CELLS, CULTURED; ENZYME ACTIVATION; HELA CELLS; HUMANS; MEMBRANE GLYCOPROTEINS; MICE; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; MUTANT PROTEINS; SUBSTRATE SPECIFICITY; TISSUE DISTRIBUTION;

EID: 38649109815     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2008.01.003     Document Type: Article

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