Na+/Ca2+-exchanger-mediated Mn2+-enhanced 1H2O MRI in hypoxic, perfused rat myocardium

Contrast Media and Molecular Imaging

Volumn 2, Issue 5, 2007, Pages 248-257

  Medina, Daniel C ^a,b   Kirkland, Dawn M ^c   Tavazoie, Masoud F ^a   Springer Jr , Charles S ^d   Anderson, Steven E ^c  

^a Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain   (United States)

^b UNIVERSITY OF BAMAKO   (Mali)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Ca2+; Heart; Hypoxia; KB R7943; MEMRI; Mn2+; MRI; Na+

Indexed keywords

CONTRAST MEDIUM; MANGANESE; SODIUM CALCIUM EXCHANGE PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOLOGICAL MODEL; CALCIUM TRANSPORT; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; EX VIVO STUDY; FEMALE; HEART MUSCLE; HEART PERFUSION; HYPERKALEMIA; HYPOXIA; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT; SARCOLEMMA; ANIMAL; CELL HYPOXIA; IN VITRO STUDY; METABOLISM; PERFUSION; SPRAGUE DAWLEY RAT;

ANIMALS; CARDIOVASCULAR DISEASES; CELL HYPOXIA; CONTRAST MEDIA; MAGNETIC RESONANCE IMAGING; MANGANESE; MYOCARDIUM; PERFUSION; RATS; RATS, SPRAGUE-DAWLEY; SODIUM-CALCIUM EXCHANGER;

EID: 38649097560     PISSN: 15554309     EISSN: 15554317     Source Type: Journal    
DOI: 10.1002/cmmi.151     Document Type: Article

References (42)

1. Hunter DR, Haworth RA, Berkoff HA. Cellular manganese uptake by the isolated perfused rat heart: A probe for the sarcolemma calcium channel. J. Mol. Cell Cardiol. 1981; 13: 823-832.
2. Koretsky AP, Silva AC. Manganese-enhanced magnetic resonance imaging (MEMRI). NMR Biomed. 2004; 17: 527-531.
3. Hu TC, Pautler RG, MacGowan GA, Koretsky AP. Manganese-enhanced MRI of mouse heart during changes in inotropy. Magn. Reson. Med. 2001; 46: 884-890.
4. Silva AC, Lee JH, Aoki I, Koretsky AP. Manganese-enhanced magnetic resonance imaging (MEMRI): Methodological and practical considerations. NMR Biomed. 2004; 17: 532-543.
5. Wendland ME Applications of manganese-enhanced magnetic resonance imaging (MEMRI) to imaging of the heart. NMR Biomed. 2004; 17 581-594.
6. Lauterbur PC. Image formation by induced local interactions: Examples employing nuclear magnetic resonance. Nature 1973; 242: 190-191.
7. Caravan P, Ellison JJ, McMurry TJ, Lauffer RB. Gadolinium(III) chelates as MRI contrast agents: Structure, dynamics, and applications. Chem. Rev. 1999; 99: 2293-2352.
8. Springer CS. Physico-chemical principles influencing magneto-pharmaceuticals. In: Gillies RJ (ed). NMR in Physiology and Biomedicine. Academic Press: Orlando, FL, 1994; 75-99.
9. 2. Neuroimage 2004; 22: 860-867.
10. 1-weighted MRI during brain activation: An approach to direct imaging of brain function. Magn. Reson. Med. 1997; 38: 378-388.
11. Wadghiri YZ, Blind JA, Duan X, Moreno C, Yu X, Joyner AL, Turnbull DH. Manganese-enhanced magnetic resonance imaging (MEMRI) of mouse brain development. NMR Biomed. 2004; 17: 613-619.
12. Pautler RG. In vivo, trans-synaptic tract-tracing utilizing manganese-enhanced magnetic resonance imaging (MEMRI). NMR Biomed. 2004; 17: 595-601.
13. Lin CP, Tseng WY, Cheng HC, Chen JH. Validation of diffusion tensor magnetic resonance axonal fiber imaging with registered manganese-enhanced optic tracts. Neuroimage 2001; 14: 1035-1047.
14. Pomeroy OH, Wendland M, Wagner S, Derugin N, Holt WW, Rocklage SM, Quay S, Higgins CB. Magnetic resonance imaging of acute myocardial ischemia using a manganese chelate, Mn-DPDP. Invest. Radiol. 1989; 24 531-536.
15. Saeed M, Wagner S, Wendland MF, Derugin N, Finkbeiner WE, Higgins CB. Occlusive and reperfused myocardial infarcts: Differentiation with Mn-DPDP-enhanced MR imaging. Radiology 1989; 172: 59-64.
16. Saeed M, Wendland MF, Takehara Y, Higgins CB. Reversible and irreversible injury in the reperfused myocardium: Differentiation with contrast material-enhanced MR imaging. Radiology 1990; 175: 633-637.
17. Wyttenbach R, Saeed M, Wendland MF, Geschwind JF, Bremerich J, Arheden H, Higgins CB. Detection of acute myocardial ischemia using first-pass dynamics of MnDPDP on inversion recovery echoplanar imaging. J. Magn. Reson. Imag. 1999; 9: 209-214.
18. Hu TC, Bao W, Lenhard SC, Schaeffer TR, Yue TL, Willette RN, Jucker BM. Simultaneous assessment of left-ventricular infarction size, function and tissue viability in a murine model of myocardial infarction by cardiac manganese-enhanced magnetic resonance imaging (MEMRI). NMR Biomed. 2004; 17: 620-626.
19. Bremerich J, Saced M, Arheden H, Higgins CB, Wendland MF. Normal and infarcted myocardium: Differentiation with cellular uptake of manganese at MR imaging in a rat model. Radiology 2000; 216: 524-530.
20. Nordhoy W, Anthonsen HW, Bruvold M, Jynge P, Krane J, Brurok H. Manganese ions as intracellular contrast agents: Proton relaxation and calcium interactions in rat myocardium. NMR Biomed. 2003; 16 82-95.
21. Nordhoy W, Anthonsen HW, Bruvold M, Brurok H, Skarra S, Krane J, Jynge P. Intracellular manganese ions provide strong T, relaxation in rat myocardium. Magn. Reson. Med. 2004; 52: 506-514.
22. Eriksson R, Johansson L, Bjerner T, Ahlstrom H. Dobutamine-induced stress affects intracellular uptake of manganese: A quantitative magnetic resonance imaging study in pigs. J. Magn. Reson. Imag. 2005; 21: 360-364.
23. Hu TC, Christian TF, Aletras AH, Taylor JL, Koretsky AP, Arai AE. Manganese enhanced magnetic resonance imaging of normal and ischemic canine heart. Magn. Reson. Med. 2005; 54: 196-200.
24. Storey P, Danias PG, Post M, Li W, Seoane PR, Harnish PP, Edelman RR, Prasad PV. Preliminary evaluation of EVP 1001-1: A new cardiac-specific magnetic resonance contrast agent with kinetics suitable for steady-state imaging of the ischemic heart. Invest. Radiol. 2003; 38: 642-652.
25. Krombach GA, Saeed M, Higgins CB, Novikov V, Wendland MF. Contrast-enhanced MR delineation of stunned myocardium with administration of MnCl(2) in rats. Radiology 2004; 230: 183-190.
26. Steenbergen C, Murphy E, Levy L, London RE. Elevation in cytosolic free calcium concentration early in myocardial ischemia in perfused rat heart. Circul. Res. 1987; 60: 700-707.
27. 2+) during ischaemia and reperfusion. Eur Heart J. 1999; K18-K30.
28. Anderson SE, Dickinson CZ, Liu H, Cala PM. Effects of Na - K - 2CI cotransport inhibition on myocardial Na and Ca during ischemia and reperfusion. Am. J. Physiol. 1996; 270: C608-C618.
29. 2+ accumulation in rabbit hearts exposed to hypoxia and acidification. Am. J. Physiol. Cell Physiol. 2003; 284: C1123-C1132.
30. Anderson SE, Murphy E, Steenbergen C, London RE, Cala PM. Na/H exchange in myocardium: Effects of hypoxia and acidification on Na and Ca. Am. J. Physiol. 1990; 259: C940-C948.
31. 2+ exchanger; 3:1 or 4:1? J. Pharmac. Sci. 2004; 96: 15-18.
32. Carmeliet E. Cardiac ionic currents and acute ischemia: From channels to arrhythmias. Physiol. Rev. 1999; 79: 917-1017.
33. Satoh H, Ginsburg KS, Qing K, Terada H, Hayashi H, Bers DM. KB-R7943 block of Ca(2+) influx via Na(+)/Ca(2+) exchange does not alter twitches or glycoside inotropy but prevents Ca(2+) overload in rat ventricular myocytes. Circulation 2000; 101: 1441-1446.
34. 2+ exchange under normal and sodium-loaded conditions in mammalian ventricles. Mol. Cell Biochem. 2003; 242: 11-17.
35. 2+ exchanger, on myocardial ischemia-reperfusion injuries. Eur J. Pharmac. 2003; 458: 155-162.
36. 2+ exchanger - lessons from knockout mice. J. Pharmac. Sci. 2004; 23-26.
37. 2+ exchange inhibition protects the rat heart from ischemia-reperfusion injury by blocking energy-wasting processes. Am. J. Physiol. Heart Circul. Physiol. 2005; 288: H1699-H1707.
38. Snabaitis AK, Shattock MJ, Chambers DJ. Comparison of polarized and depolarized arrest in the isolated rat heart for long-term preservation. Circulation 1997; 96: 3148-3156.
39. Blaustein MP, Lederer WJ. Sodium/calcium exchange: Its physiological implications. Physiol. Rev. 1999; 79: 763-854.
40. Rezkalla SH, Kloner RA. No-reflow phenomenon. Circulation 2002; 105: 656-662.
41. Medina DC, Kirkland DM, Cala PM, Springer CS, Anderson SE. Proc. Int. Soc. Magn. Reson. Med. 2005; 13: 1688.
42. Crossgrove J, Zheng W. Manganese toxicity upon overexposure. NMR Biomed. 2004; 17: 544-553.