α-melanocyte-stimulating hormone gene transfer attenuates inflammation after bile duct ligation in the rat

Digestive Diseases and Sciences

Volumn 53, Issue 2, 2008, Pages 556-563

  Wang, Chien Che ^a   Lin, Jia Wei ^b   Lee, Liang Ming ^b   Lin, Chien Min ^b   Chiu, Wen Ta ^b   Pai, Hsin Te ^a   Hung, Kuo Sheng ^a,b  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Melanocyte stimulating hormone; Bile duct ligation; Cholestasis; Gene transfer; Inflammation

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA INTERMEDIN; BILIRUBIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BILE DUCT LIGATION; CHOLESTASIS; CONTROLLED STUDY; ENZYME ACTIVITY; GENE SEQUENCE; GENE TRANSFER; GENETIC TRANSFECTION; HEPATITIS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; KUPFFER CELL; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; STELLATE CELL; UPREGULATION;

ALANINE TRANSAMINASE; ALPHA-MSH; ANIMALS; CHOLESTASIS, EXTRAHEPATIC; COMMON BILE DUCT; GENE THERAPY; GENE TRANSFER TECHNIQUES; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1BETA; KUPFFER CELLS; LIGATION; MALE; NEUTROPHILS; NITRIC OXIDE SYNTHASE TYPE II; PLASMIDS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 38649088272     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-007-9901-6     Document Type: Article

References (20)

1. Trauner M, Meier PJ, Boyer JL (1998) Molecular pathogenesis of cholestasis. N Engl J Med 339:1217-1227
2. Greim H, Trulzsch D, Czygan P et al (1972) Mechanism of cholestasis. 6. Bile acids in human livers with or without biliary obstruction. Gastroenterology 63:846-850
3. Miyoshi H, Rust C, Roberts PJ et al (1999) Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas. Gastroenterology 117:669-677
4. Chiao H, Foster S, Thomas R et al (1996) α-melanocyte-stimulating hormone reduces endotoxin-induced liver inflammation. J Clin Invest 97:2038-2044
5. Rajora N, Boccoli G, Catania A, Lipton JM (1997) Alpha-MSH modulates experimental inflammatory bowel disease. Peptides 18:381-385
6. Airaghi L, Lettino M, Manfredi MG et al (1995) Endogenous cytokine antagonists during myocardial ischemia and thrombolytic therapy. Am Heart J 130:204-211
7. Cannon JG, Tatro JB, Reichlin S, Dinarello CA (1986) Alpha melanocyte stimulating hormone inhibits immunostimulatory and inflammatory actions of interleukin 1. J Immunol 137:2232-2236
8. Rajora N, Boccoli G, Burns D et al (1997) Alpha-MSH modulates local and circulating tumor necrosis factor-alpha in experimental brain inflammation. J Neurosci 17:2181-2186
9. Friedman SL (2000) Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J Biol Chem 275:2247-2250
10. Wang CH, Liang CL, Huang LT et al (2004) Single intravenous injection of naked plasmid DNA encoding erythropoietin provides neuroprotection in hypoxia-ischemia rats. Biochem Biophys Res Commun 314:1064-1071
11. Wang CH, Jawan B, Lee TH et al (2004) Single injection of naked plasmid encoding α-melanocyte stimulating hormone protects against thioacetamide-induced acute liver failure in mice. Biochem Biophys Res Commun 322:153-161
12. Hung KS, Tsai SH, Lee TC et al (2007) Gene transfer of insulin like growth factor-I providing neuroprotection after spinal cord injury in rats. J Neurosurg Spine 6:35-46
13. Etemad-Moghadam B, Chen H, Yin P et al (2002) Inhibition of NF-kappa B activity by plasmid expressed alpha-MSH peptide. J Neuroimmunol 125:23-29
14. Liu F, Song YK, Liu D (1999) Hydrodynamic-based transfection in animals by systemic administration of plasmid DNA. Gene Ther 6:1258-1266
15. Rudman D, Hollins BM, Kutmer MH et al (1983) Three types of alpha-melanocyte-stimulating hormone: bioactivities and half-lives. Am J Physiol 245:E47-E54
16. Rothuizen J, Biewenga WJ, Mol JA (1995) Chronic glucocorticoid excess and impaired osmoregulation of vasopressin release in dogs with hepatic encephalopathy. Domest Anim Endocrinol 12:13-24
17. Gujral JS, Farhood A, Bajt ML, Jaeschke H (2003) Neutrophils aggravate acute liver injury during obstructive cholestasis in bile duct-ligated mice. Hepatology 38:355-363
18. Essani NA, Fisher MA, Farhood A et al (1995) Cytokine-induced upregulation of hepatic intercellular adhesion molecule-1 messenger RNA expression and its role in the pathophysiology of murine endotoxin shock and acute liver failure. Hepatology 21:1632-1639
19. Catania A, Monno R, Motta P et al (1995) Influences of the neuropeptide alfa-MSH on cytokine production by peripheral blood mononuclear cells stimulated with gp120. VIII Research Project on AIDS, Rome, p 145
20. Li J, Billiar TR (1999) Nitric oxide. IV. Determinants of nitric oxide protection and toxicity in liver. Am J Physiol 276:G1069-G1073