Glypican 4, a membrane binding protein for bactericidal/permeability- increasing protein signaling pathways in retinal pigment epithelial cells

Investigative Ophthalmology and Visual Science

Volumn 48, Issue 12, 2007, Pages 5750-5755

  Geraldes, Pedro ^a   Yamagata, Michiko ^a   Rook, Susan L ^a   Sassa, Yukio ^a   Ma, Ronald C ^a   Clermont, Allen ^a   Gao, Benbo ^a   Aiello, Lloyd Paul ^a,b   Feener, Edward P ^a,b   King, George L ^a,b  

^a JOSLIN DIABETES CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; BACTERICIDAL PERMEABILITY INCREASING PROTEIN; DNA; ENZYME; GLYPICAN; GLYPICAN 4; HEPARITINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE PHOSPHODIESTERASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; ANTIMICROBIAL CATIONIC PEPTIDE; HEPARITINSULFATE LYASE; MEMBRANE PROTEIN; MESSENGER RNA; PHOSPHOLIPASE C; PLASMA PROTEIN; PLATELET DERIVED GROWTH FACTOR B; POLYSACCHARIDE LYASE; VASCULOTROPIN A;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; PERICYTE; PIGMENT CELL; PIGMENT EPITHELIUM; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY; ANIMAL; CATTLE; CELL CULTURE; CHEMISTRY; DRUG EFFECT; GENETICS; IMMUNOBLOTTING; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; BLOOD PROTEINS; CATTLE; CELLS, CULTURED; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLYPICANS; IMMUNOBLOTTING; MEMBRANE PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; PIGMENT EPITHELIUM OF EYE; POLYSACCHARIDE-LYASES; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-SIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY; TYPE C PHOSPHOLIPASES; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 38549167495     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.07-0470     Document Type: Article

References (31)

1. Weiss J, Eisbach P, Olsson I, Odeberg H. Purification and characterization of a potent bactericidal and membrane active protein from the granules of human polymorphonuclear leukocytes. J Biol Chem. 1978;253:2664-2672.
2. Shafer WM, Martin LE, Spitznagel JK. Cationic antimicrobial proteins isolated from human neutrophil granulocytes in the presence of diisopropyl fluorophosphate. Infect Immun. 1984;45:29-35.
3. Canny G, Levy O, Furuta GT, et al. Lipid mediator-induced expression of bactericidal/permeability-increasing protein (BPI) in human mucosal epithelia. Proc Natl Acad Sci USA. 2002;99:3902-3907.
4. Yamagata M, Rook SL, Sassa Y, et al. Bactericidal/permeability-increasing protein's signaling pathways and its retinal trophic and anti-angiogenic effects. FASEB J. 2006;20:2058-2067.
5. van der Schaft DW, Toebes EA, Haseman JR, Mayo KH, Griffioen AW. Bactericidal/permeability-increasing protein (BPI) inhibits angiogenesis via induction of apoptosis in vascular endothelial cells. Blood. 2000;96:176-181.
6. Gazzano-Santoro H, Parent JB, Grinna L, et al. High-affinity binding of the bactericidal/permeability-increasing protein and a recombinant amino-terminal fragment to the lipid A region of lipopotysaccharide. Infect Immun. 1992;60:4754-4761.
7. Weiss J, Elsbach P, Shu C, et al. Human bactericidal/permeability- increasing protein and a recombinant NH2-terminal fragment cause killing of serum-resistant Gram-negative bacteria in whole blood and inhibit tumor necrosis factor release induced by the bacteria. J Clin Invest. 1992;90:1122-1130.
8. Rauniyar RK, Suzuma K, King AL, Aiello LP, King GL. Differential effects of bactericidal/permeability-increasing protein (BPI) analogues on retinal neovascularization and retinal pericyte growth. Invest Ophthalmol Vis Sci. 2002;43:503-509.
9. Kuwabara T, Cogan DG. Retinal vascular patterns, VI: mural cells of the retinal capillaries. Arch Ophthalmol. 1963;69:492-502.
10. King GL, Suzuma K. Pigment-epithelium-derived factor-a key coordinator of retinal neuronal and vascular functions. N Engl J Med. 2000;342:349-351.
11. Shima DT, Adamis AP, Ferrara N, et al. Hypoxic induction of endothelial cell growth factors in retinal cells: identification and characterization of vascular endothelial growth factor (VEGF) as the mitogen. Mol Med. 1995;1:182-193.
12. Betsholtz C. Role of platelet-derived growth factors in mouse development. Int J Dev Biol. 1995;39:817-825.
13. Lindahl P, Johansson BR, Leveen P, Betsholtz C. Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science. 1997;277:242-245.
14. Wilkinson-Berka JL, Babic S, De Gooyer T, et al. Inhibition of platelet-derived growth factor promotes pericyte loss and angiogenesis in ischemic retinopathy. Am J Pathol. 2004;164:1263-1273.
15. King GL, Goodman AD, Buzney S, Moses A, Kahn CR. Receptors and growth-promoting effects of insulin and insulinlike growth factors on cells from bovine retinal capillaries and aorta. J Clin Invest. 1985;75:1028-1036.
16. King GL, Berman AB, Bonner-Weir S, Carson MP. Regulation of vascular permeability in cell culture. Diabetes. 1987;36:1460-1467.
17. Little RG, Keiner DN, Lim E, Burke DJ, Cordon PJ. Functional domains of recombinant bactericidal/permeability increasing protein (rBPI23). J Biol Chem. 1994;269:1865-1872.
18. Ford-Perriss M, Turner K, Guimond S, et al. Localisation of specific heparan sulfate proteoglycans during the proliferative phase of brain development. Dev Dyn. 2003;227:170-184.
19. Watanabe K, Yamada H, Yamaguchi Y. K-glypican: a novel GPI-anchored heparan sulfate proteoglycan that is highly expressed in developing brain and kidney. J Cell Biol. 1995;130:1207-1218.
20. Hagihara K, Watanabe K, Chun J, Yamaguchi Y. Glypican-4 is an FGF2-binding heparan sulfate proteoglycan expressed in neural precursor cells. Dev Dyn. 2000;219:353-367.
21. Filmus J, Selleck SB. Glypicans: proteoglycans with a surprise. J Clin Invest. 2001;108:497-501.
22. O'Brian CA, Ward NE. Biology of the protein kinase C family. Cancer Metastasis Rev. 1989;8:199-214.
23. Takahashi M, Horiuchi Y, Tezuka T. Presence of bactericidal/permeability- increasing protein in human and rat skin. Exp Dermatol. 2004;13:55-60.
24. Palacin M, Estevez R, Bertran J, Zorzano A. Molecular biology of mammalian plasma membrane amino acid transporters. Physiol Rev. 1998;78:969-1054.
25. Levine KB, Cloherty EK, Hamill S, Carruthers A. Molecular determinants of sugar transport regulation by ATP. Biochemistry. 2002;41:12629-12638.
26. Filmus J. The contribution of in vivo manipulation of gene expression to the understanding of the function of glypicans. Glycoconj J. 2002;19:319-323.
27. Fransson LA, Belting M, Cheng F, Jonsson M, Mani K, Sandgren S. Novel aspects of glypican glycobiology. Cell Mol Life Sci. 2004;61:1016-1024.
28. Bernfield M, Gotte M, Park PW, et al. Functions of cell surface heparan sulfate proteoglycans. Annu Rev Biochem. 1999;68:729-777.
29. Karumanchi SA, Jha V, Ramchandran R, et al. Cell surface glypicans are low-affinity endostatin receptors. Mol Cell. 2001;7:811-822.
30. Karihaloo A, Kale S, Rosenblum ND, Cantley LG. Hepatocyte growth factor-mediated renal epithelial branching morphogenesis is regulated by glypican-4 expression. Mol Cell Biol. 2004;24:8745-8752.
31. Midorikawa Y, Ishikawa S, Iwanari H, et al. Glypican-3, overexpressed in hepatocellular carcinoma, modulates FGF2 and BMP-7 signaling. Int J Cancer. 2003;103:455-465.