Three-dimensional quantitative structure-activity relationship modeling of γ-secretase inhibitors using molecular field analysis

Chemical Biology and Drug Design

Volumn 71, Issue 2, 2008, Pages 155-166

  Sammi, Tarnvir ^a   Silakari, Om ^a   Ravikumar, Muttineni ^b  

^a PUNJABI UNIVERSITY   (India)

^b GVK BIOSCIENCES PVT LTD   (India)

Author keywords

Drug design; Drug discovery; Molecular modeling; Therapeutic target

Indexed keywords

GAMMA SECRETASE INHIBITOR;

ALZHEIMER DISEASE; ARTICLE; DRUG DESIGN; DRUG STRUCTURE; ENZYME STRUCTURE; IC 50; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS;

AMYLOID PRECURSOR PROTEIN SECRETASES; DRUG EVALUATION, PRECLINICAL; ELECTROSTATICS; ENZYME INHIBITORS; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 38549155452     PISSN: 17470277     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2007.00622.x     Document Type: Article

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