Novel GSK-3β inhibitors from sequential virtual screening

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 2, 2008, Pages 636-643

  Kim, Hye Jung ^a,b   Choo, Hyunah ^a   Cho, Yong Seo ^a   No, Kyoung Tai ^b   Pae, Ae Nim ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Yonsei University   (South Korea)

Author keywords

GSK 3 (glycogen synthase kinase 3) inhibitors; HipHop; RP (recursive partitioning); SQSP (sequential virtual screening)

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; GLYCOGEN SYNTHASE KINASE 3BETA; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; DRUG ACTIVITY; DRUG BINDING; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG TARGETING; PHARMACOPHORE; THREE DIMENSIONAL IMAGING; CHEMICAL STRUCTURE; COMBINATORIAL CHEMISTRY; CONFORMATION; DRUG ANTAGONISM; DRUG DESIGN; FACTUAL DATABASE; HUMAN; X RAY CRYSTALLOGRAPHY;

COMBINATORIAL CHEMISTRY TECHNIQUES; CRYSTALLOGRAPHY, X-RAY; DATABASES, FACTUAL; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE;

EID: 38549128330     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.10.047     Document Type: Article

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