Poly(ADP-ribose) polymerase-1 inhibition increases expression of heat shock proteins and attenuates heat stroke-induced liver injury

Critical Care Medicine

Volumn 36, Issue 2, 2008, Pages 526-534

  Mota, Rubén A ^a   Hernández Espinosa, David ^b   Galbis Martinez, Lilian ^c   Ordoñez, Adriana ^b   Miñano, Antonia ^b   Parrilla, Pascual ^a   Vicente, Vicente ^b   Corral, Javier ^b   Yélamos, José ^a,d  

^a HOSPITAL UNIVERSITARIO VIRGEN DE LA ARRIXACA   (Spain)

^b HOSPITAL UNIVERSITARIO MORALES MESEGUER   (Spain)

^c HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^d HOSPITAL DEL MAR   (Spain)

Author keywords

Heat shock proteins; Heat stroke; Poly(ADP ribose) polymerase; Poly(ADP ribose) polymerase inhibitors

Indexed keywords

3 AMINOBENZAMIDE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70; INTERLEUKIN 1BETA; INTERLEUKIN 6; N (5,6 DIHYDRO 6 OXO 2 PHENANTHRIDINYL) 2 DIMETHYLAMINOACETAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CONTROLLED STUDY; HEAT STROKE; HEAT TOLERANCE; LABORATORY; LIVER HISTOLOGY; LIVER INJURY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECTUM TEMPERATURE; SURVIVAL; WILD TYPE;

EID: 38549127670     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000299735.43699.E9     Document Type: Article

References (39)

1. Bouchama A, Knochel JP: Heat stroke. N Engl J Med 2002; 346:1978-1988
2. Kosatsky T: The 2003 European heat waves. Euro Surveill 2005; 10:148-149
3. Patz JA, Campbell-Lendrum D, Holloway T, et al: Impact of regional climate change on human health. Nature 2005; 438:310-317
4. Kurahashi K, Kajikawa O, Sawa T, et al: Pathogenesis of septic shock in Pseudomonas aeruginosa pneumonia. J Clin Invest 1999; 104:743-750
5. Bouchama A, Parhar RS, el Yazigi A, et al: Endotoxemia and release of tumor necrosis factor and interleukin 1 alpha in acute heatstroke. J Appl Physiol 1991; 70:2640-2644
6. Bouchama A, al Sedairy S, Siddiqui S, et al: Elevated pyrogenic cytokines in heatstroke. Chest 1993; 104:1498-1502
7. Chang DM: The role of cytokines in heat stroke. Immunol Invest 1993; 22:553-561
8. Hassanein T, Razack A, Gavaler JS, et al: Heatstroke: Its clinical and pathological presentation, with particular attention to the liver. Am J Gastroenterol 1992; 87:1382-1389
9. Lee WC, Wen HC, Chang CP, et al: Heat shock protein 72 overexpression protects against hyperthermia, circulatory shock, and cerebral ischemia during heatstroke. J Appl Physiol 2006; 100:2073-2082
10. Singleton KD, Wischmeyer PE: Oral glutamine enhances heat shock protein expression and improves survival following hyperthermia. Shock 2006; 25:295-299
11. Wang ZZ, Wang CL, Wu TC, et al: Autoantibody response to heat shock protein 70 in patients with heatstroke. Am J Med 2001; 111:654-657
12. Schreiber V, Dantzer F, Ame JC, et al: Poly(ADP-ribose): Novel functions for an old molecule. Nat Rev Mol Cell Biol 2006; 7:517-528
13. Corral J, Yelamos J, Hernandez-Espinosa D, et al: Role of lipopolysaccharide and cecal ligation and puncture on blood coagulation and inflammation in sensitive and resistant mice models. Am J Pathol 2005; 166:1089-1098
14. Cuzzocrea S: Shock, inflammation and PARP. Pharmacol Res 2005; 52:72-82
15. Jagtap P, Szabo C: Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors. Nat Rev Drug Discov 2005; 4:421-440
16. Mota RA, Sanchez-Bueno F, Saenz L, et al: Inhibition of poly(ADP-ribose) polymerase attenuates the severity of acute pancreatitis and associated lung injury. Lab Invest 2005; 85:1250-1262
17. Oliver FJ, Menissier-de Murcia J, Nacci C, et al: Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice. EMBO J 1999; 18:4446-4454
18. Gero D, Szabo C: Role of the peroxynitritepoly (ADP-ribose) polymerase pathway in the pathogenesis of liver injury. Curr Pharm Des 2006; 12:2903-2910
19. Menissier-de Murcia J, Niedergang C, Trucco C, et al: Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells. Proc Natl Acad Sci U S A 1997; 94:7303-7307
20. Chatterjee S, Premachandran S, Sharma D, et al: Therapeutic treatment with L-arginine rescues mice from heat stroke-induced death: Physiological and molecular mechanisms. Shock 2005; 24:341-347
21. Carrillo A, Monreal Y, Ramirez P, et al: Transcription regulation of TNF-alpha-early response genes by poly(ADP-ribose) polymerase-1 in murine heart endothelial cells. Nucleic Acids Res 2004; 32:757-766
22. Ouararhni K, Hadj-Slimane R, Ait-Si-Ali S, et al: The histone variant mH2A1.1 interferes with transcription by down-regulating PARP-1 enzymatic activity. Genes Dev 2006; 20:3324-3336
23. Szabo C, Wong HR, Salzman AL: Pre-exposure to heat shock inhibits peroxynitrite-induced activation of poly(ADP) ribosyl-transferase and protects against peroxynitrite cytotoxicity in J774 macrophages. Eur J Pharmacol 1996; 315:221-226
24. Leon LR, DuBose DA, Mason CW: Heat stress induces a biphasic thermoregulatory response in mice. Am J Physiol Regul Integr Comp Physiol 2005; 288:R197-R204
25. Yuan QX, Marceau N, French BA, et al: Heat shock in vivo induces Mallory body formation in drug primed mouse liver. Exp Mol Pathol 1995; 63:63-76
26. De Maio A: Heat shock proteins: Facts, thoughts, and dreams. Shock 1999; 11:1-12
27. Konishi T, Karasaki Y, Nomoto M, et al: Induction of heat shock protein 70 and nucleolin and their intracellular distribution during early stage of liver regeneration. J Biochem (Tokyo) 1995; 117:1170-1177
28. Ohtsuka K, Laszlo A: The relationship between hsp 70 localization and heat resistance. Exp Cell Res 1992; 202:507-518
29. Sun JZ, Tang XL, Knowlton AA, et al: Late preconditioning against myocardial stunning: An endogenous protective mechanism that confers resistance to postischemic dysfunction 24 h after brief ischemia in conscious pigs. J Clin Invest 1995; 95:388-403
30. Tanonaka K, Toga W, Takahashi M, et al: Hsp70 attenuates hypoxia/reoxygenation-induced activation of poly(ADP-ribose) synthetase in the nucleus of adult rat cardiomyocytes. Mol Cell Biochem 2003; 248:149-155
31. Virag L, Szabo C: The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol Rev 2002; 54:375-429
32. Leon LR, Blaha MD, DuBose DA: Time course of cytokine, corticosterone, and tissue injury responses in mice during heat strain recovery. J Appl Physiol 2006; 100:1400-1409
33. Sevigny M, Garnier P, Kauppinen T, et al: Heat shock-induced Hsp70 expression in murine astrocytes does not require poly(ADP-ribose) polymerase activity. Cell Physiol Biochem 2003; 13:297-300
34. Tulin A, Spradling A: Chromatin loosening by poly(ADP)-ribose polymerase (PARP) at Drosophila puff loci. Science 2003; 299:560-562
35. Fossati S, Formentini L, Wang ZQ, et al: Poly(ADP-ribosyl)ation regulates heat shock factor-1 activity and the heat shock response in murine fibroblasts. Biochem Cell Biol 2006; 84:703-712
36. Zingarelli B, Hake PW, O'Connor M, et al: Differential regulation of activator protein-1 and heat shock factor-1 in myocardial ischemia and reperfusion injury: Role of poly(ADP-ribose) polymerase-1. Am J Physiol Heart Circ Physiol 2004; 286:H1408-H1415
37. Yang YL, and Lin MT: Heat shock protein expression protects against cerebral ischemia and monoamine overload in rat heatstroke. Am J Physiol 1999; 276:H1961-H1967
38. Banasik M, Komura H, Shimoyama M, et al: Specific inhibitors of poly (ADP-ribose) synthetase and mono(ADP-ribosyl) transferase. J Biol Chem 1992; 267:1569-1575
39. Iwashita A, Tojo N, Matsuura S, et al: A novel and potent poly(ADP-ribose) polymerase-1 inhibitor, FR247304 (5-chloro-2-[3-(4-phenyl-3,6- dihydro-1(2H)-pyridinyl)propyl]-4(3H)-quinazo linone), attenuates neuronal damage in in vitro and in vivo models of cerebral ischemia. J Pharmacol Exp Ther 2004; 310:425-436