Pre-exposure to heat shock inhibits peroxynitrite-induced activation of poly(ADP) ribosyltransferase and protects against peroxynitrite cytotoxicity in J774 macrophages

European Journal of Pharmacology

Volumn 315, Issue 2, 1996, Pages 221-226

  Szabó, Csaba ^a   Wong, Hector R ^a   Salzman, Andrew L ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Endotoxin; Inflammation; Mitochondrial respiration; Nitric oxide (NO); Shock; Superoxide

Indexed keywords

HEAT SHOCK PROTEIN 70; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PEROXYNITRITE; SUPEROXIDE;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL PROTECTION; CONTROLLED STUDY; ENZYME ACTIVATION; HEAT SHOCK; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; MACROPHAGE; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; CELLS, CULTURED; ENZYME ACTIVATION; HEAT-SHOCK PROTEINS; MACROPHAGES; MICE; MITOCHONDRIA; NITRATES; POLY(ADP-RIBOSE) POLYMERASES;

EID: 0030583715     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(96)00628-0     Document Type: Article

References (39)

1. Bellmann, K., J. Wenz, R. Radons, V. Burkart, R. Kleemann and H. Kolb, 1995, Heat shock induces resistance in rat pancreatic islet cells against nitric oxide, oxygen radicals and streptozotocin toxicity in vitro, J. Clin. Invest. 95, 2840.
2. Berridge, M.V. and A.S. Tan, 1993, Characterization of the cellular reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT): subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction, Arch. Biochem. Biophys. 303, 474.
3. Brunelli, L., J. Crow and J Beckman, 1995, The comparative toxicity of nitric oxide and peroxynitrite to Escherichia coli, 316, 327.
4. Burkart, V., A. Gross-Eick, K. Bellmann, J. Radons and H. Kolb, 1995, Suppression of nitric oxide toxicity in islet cells by alpha-tocopherol, FEBS Lett. 364, 259.
5. Castro, L., M. Rodriguez and R. Radi, 1994, Aconitase is readily inactivated by peroxynitrite, but not by its precursor, nitric oxide, J. Biol. Chem. 269, 29409.
6. Dawson, V.L., 1995, Nitric oxide: role in neurotoxicity, Clin. Exp. Pharmacol. Physiol. 22, 305.
7. Guzman, N.J., M.Z. Fang, S.S. Tang, J.R. Ingelfinger and L.C. Garg, 1995, Autocrine inhibition of Na+ /K(+)-ATPase by nitric oxide in mouse proximal tubule epithelial cells, J. Clin. Invest. 95, 2083.
8. Hausladen, A. and I. Fridovich, 1994, Superoxide and peroxynitrite inactivate aconitases, but nitric oxide does not, J. Biol. Chem. 269, 29405.
9. Hu, P., H. Ischiropoulos, J.S. Beckman and S. Matalon, 1994, Peroxynitrite inhibition of oxygen consumption and sodium transport in alveolar type II cells, Am. J. Physiol. 266, L628.
10. Inoue, S. and S. Kawanishi, 1995, DNA damage induced by simultaneous generation of nitric oxide and superoxide. FEBS Lett. 371, 86.
11. Jaattela, M. and D. Wissing, 1993, Heat-shock proteins protect cells from monocyte cytotoxicity: possible mechanism of self-protection, J. Exp. Med. 177, 231.
12. Kapoor, M. and J. Lewis, 1987, Heat shock induces peroxidase activity in Neurospora crassa and confers tolerance toward oxidative stress, Biochem. Biophys. Res. Commun. 147, 904.
13. Kaur, H. and B. Halliwell, 1994, Evidence for nitric oxide-mediated oxidative damage in chronic inflammation; nitrolyrosine in serum and synovial fluid from rheumatoid patients, FEBS Lett. 350, 9.
14. Leeson, M.C. and D.C. Morrison, 1994, Induction of proinflammatory responses in human monocytes by particulate and soluble forms of lipopolysaccharide, Shock 2, 235.
15. Li, G.C. and Z. Werb, 1982, Correlation between synthesis of heat shock proteins and development of thermotolerance in Chinese hamster fibroblasts, Proc. Natl. Acad. Sci. USA 79, 3218.
16. Li, G.C., L. Li, Y.K. Liu, J.Y. Mak, L. Chen and W.M.F. Lee, 1992, Thermal response of rat fibroblasts stably transfectcd with human 70-kD heat shock protein-encoding gene, Proc. Natl. Acad. Sci. USA 89, 2036.
17. Lindquist, S.C., 1986, The heat-shock response, Annu. Rev. Biochem. 55, 1151.
18. Miller, M.J.S., J.H. Thompson, X.J. Zhang, H. Sadowska-Krowicka, J.L. Kakkis, U.K. Munshi, M. Sandoval, J. Rossi, S. Elobi-Childress, J. Beckman, Y.Z. Ye, C.P. Rodi, P. Manning, M. Currie and D.A. Clark, 1995, Role of inducible nitric oxide synthase expression and peroxynitrite formation in guinea pig ileitis, Gastroenterology 109, 1475.
19. Minowada, G. and J. Welch, 1995, Clinical implications of the stress response, J. Clin. Invest. 95, 3.
20. Phelphs, D.T., T.J. Ferro, P.J. Higgins, R. Shankar, D.M. Parkler and A. Johnson, 1995, TNF-alpha induces peroxynitrite-mediated depletion of lung endothelial glutathione via protein kinase C, Am. J. Physiol. 269, L551.
21. Pryor, W. and G. Squadrito, 1995, The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide, Am. J. Physiol. 268, L699.
22. Radi, R., J.S. Beckman, K.M. Bush and B.A. Freeman, 1991, Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide, Arch. Biochem. Biophys. 288, 481.
23. Salgo, M.G., E. Bermudez, G. Squadrito and W. Pryor, 1995, DNA damage and oxidation of thiols peroxynitrite causes in rat thymocytes, Arch. Biochem. Biophys. 322, 500.
24. Schiller, H.J., P.M. Reilly and G.B. Bulkley, 1993, Tissue perfusion in critical illnesses. Antioxidant therapy, Crit. Care Med. 21, S92.
25. Squadrito, G.L. and W.A. Pryor, 1995, The formation of peroxynitrite in vivo from nitric oxide and superoxide, Chem.-Biol. Interact. 96, 203.
26. Sung, Y.J. and R.R. Dietert, 1994, Nitric oxide-induced mitochondrial injury among chicken NO-generating and target leukocytes, J. Leukocyte Biol. 56, 52.
27. Szabó, C., 1995, Alterations in nitric oxide production in various forms of circulatory shock, New Horizons 3, 2.
28. Szabó, C., 1996, The role of peroxynitrite in the pathophysiology of shock, inflammation and ischemia-reperfusion injury, Shock 6, 77.
29. Szabó, C. and A.L. Salzman, 1995, Endogenous peroxynitrite is involved in the inhibition of cellular respiration in immuno-stimulated J774.2 macrophages, Biochem. Biophys. Res. Commun. 209, 739.
30. Szabó C., G.J. Southan and C. Thiemermann, 1994, Beneficial effects and improved survival in rodent models of septic shock with S-methyl-isothiourea sulfate, a novel, potent and selective inhibitor of inducible nitric oxide synthase, Proc. Natl. Acad. Sci. USA 91, 12472.
31. Szabó, C., A.L. Salzman and H. Ischiropoulos, 1995a, Endotoxin triggers the expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in the rat aorta in vivo, FEBS Lett. 363, 235.
32. Szabó, C., A.L. Salzman and H. Ischiropoulos, 1995b, Peroxynitrite-mediated oxidation of dihydrorhodamine 123 occurs in early stages of endotoxic and hemorrhagic shock and ischemia-reperfusion injury, FEBS Lett. 372, 229.
33. Szabó, C., B. Zingarelli, M. O'Connor and A.L. Salzman, 1996a, DNA strand breakage, activation of poly-ADP ribosyl synthetase, and cellular energy depletion are involved in the cytotoxicity in macrophages and smooth muscle cells exposed to peroxynitrite, Proc. Natl. Acad. Sci. USA 93, 1753.
34. Szabó, C., B. Zingarelli and A.L. Salzman, 1996b, Role of poly-ADP ribosyltransferase activation in the nitric oxide-and peroxynitrite-induced vascular failure, Circ. Res. 78, 1051.
35. Villar, J., S.P. Ribeiro, J.B.M. Mullen, M. Kuliszewski, M. Post and A.S. Slutsky, 1994, Induction of the heat shock response reduces mortality rate and organ damage in a sepsis-induced acute lung injury model, Crit. Care Med. 22, 914.
36. Wizemann, T.M., C.R. Gardner, J.D. Laskin, S. Quinones, S.K. Durham, N.L. Goller, S.T. Ohnishi and D.L. Laskin, 1994, Production of nitric oxide and peroxynitrite in the lung during acute endotoxemia, J. Leukocyte Biol. 56, 759.
37. Wong, H.R., J.D. Finder, K. Wasserloos and B.R. Pitt, 1995, Expression of inducible nitric oxide synthase in cultured rat pulmonary artery smooth muscle cells is inhibited by the heat shock response, Am. J. Physiol. 269, L843.
38. Zingarelli, B., M. O'Connor, H.R. Wong, A.L. Salzman and C. Szabó, 1996a, Peroxynitrite-mediated DNA strand breakage activates poly-ADP ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide, J. Immunol. 156, 350.
39. Zingarelli, B., A.L. Salzman and C. Szabó, 1996b, Protective effects of nicotinamide against nitric oxide-mediated vascular failure in endotoxic shock: potential involvement of poly ADP ribosyl synthetase, Shock 5, 258.