Elevated hydrostatic pressure promotes protein recovery from formalin-fixed, paraffin-embedded tissue surrogates

Laboratory Investigation

Volumn 88, Issue 2, 2008, Pages 185-195

  Fowler, Carol B ^a   Cunningham, Robert E ^a   Waybright, Timothy J ^b   Blonder, Josip ^b   Veenstra, Timothy D ^b   O'Leary, Timothy J ^c   Mason, Jeffrey T ^a  

^a ARMED FORCES INSTITUTE OF PATHOLOGY   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Antigen retrieval; Formalin fixed, paraffin embedded tissue; High pressure protein extraction; Lysozyme; Mass spectrometry; Proteomics

Indexed keywords

AMINO ACID; ASPARTIC ACID; COPPER CHLORIDE; DODECYL SULFATE SODIUM; LYSOZYME;

ANTIGEN RETRIEVAL; ARTICLE; HYDROSTATIC PRESSURE; MASS SPECTROMETRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN MODIFICATION; PROTEOMICS; TEMPERATURE;

BUFFERS; FIXATIVES; FORMALDEHYDE; HYDROGEN-ION CONCENTRATION; HYDROSTATIC PRESSURE; MASS SPECTROMETRY; MURAMIDASE; PARAFFIN EMBEDDING; PROTEINS; TEMPERATURE; TIME FACTORS; TISSUE BANKS;

EID: 38549099794     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.3700708     Document Type: Article

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