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Volumn 196, Issue 9, 2007, Pages 1409-1415

A checkpoint in the cell cycle progression as a therapeutic target to inhibit HIV replication

Author keywords

[No Author keywords available]

Indexed keywords

CD24 ANTIGEN; CD28 ANTIGEN; CD69 ANTIGEN; HYDROXYUREA; MYCOPHENOLIC ACID; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; DRUG DERIVATIVE; ENZYME INHIBITOR; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER;

EID: 38449104765     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/521832     Document Type: Article
Times cited : (9)

References (47)
  • 1
    • 0026083131 scopus 로고
    • Cell dysfunction and depletion in AIDS: The programmed cell death hypothesis
    • Ameisen JC, Capron A. Cell dysfunction and depletion in AIDS: the programmed cell death hypothesis. Immunol Today 1991; 12:102-5.
    • (1991) Immunol Today , vol.12 , pp. 102-105
    • Ameisen, J.C.1    Capron, A.2
  • 2
    • 0035912232 scopus 로고    scopus 로고
    • The dynamics of CD4+ T-cell depletion in HIV disease
    • McCune JM. The dynamics of CD4+ T-cell depletion in HIV disease. Nature 2001; 410:974-9.
    • (2001) Nature , vol.410 , pp. 974-979
    • McCune, J.M.1
  • 4
    • 0033624622 scopus 로고    scopus 로고
    • The impact of HIV on naive T-cell homeostasis
    • Grossman Z, Paul WE. The impact of HIV on naive T-cell homeostasis. Nat Med 2000; 6:976-7.
    • (2000) Nat Med , vol.6 , pp. 976-977
    • Grossman, Z.1    Paul, W.E.2
  • 5
    • 0142186676 scopus 로고    scopus 로고
    • Subpopulations of long-lived and short-lived T cells in advanced HIV-1 infection
    • Hellerstein MK, Hoh RA, Hanley MB, et al. Subpopulations of long-lived and short-lived T cells in advanced HIV-1 infection. J Clin Invest 2003; 112:956-66.
    • (2003) J Clin Invest , vol.112 , pp. 956-966
    • Hellerstein, M.K.1    Hoh, R.A.2    Hanley, M.B.3
  • 6
    • 0037373269 scopus 로고    scopus 로고
    • HIV envelope induces virus expression from resting CD4+ T cells isolated from HIV-infected individuals in the absence of markers of cellular activation or apoptosis
    • Kinter AL, Umscheid CA, Arthos J, et al. HIV envelope induces virus expression from resting CD4+ T cells isolated from HIV-infected individuals in the absence of markers of cellular activation or apoptosis. J Immunol 2003; 170:2449-55.
    • (2003) J Immunol , vol.170 , pp. 2449-2455
    • Kinter, A.L.1    Umscheid, C.A.2    Arthos, J.3
  • 7
    • 17844376742 scopus 로고    scopus 로고
    • Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells
    • Li Q, Duan L, Estes JD, et al. Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells. Nature 2005; 434:1148-52.
    • (2005) Nature , vol.434 , pp. 1148-1152
    • Li, Q.1    Duan, L.2    Estes, J.D.3
  • 8
    • 0025238945 scopus 로고
    • HIV-1 replication is controlled at the level of T cell activation and proviral integration
    • Stevenson M, Stanwick TL, Dempsey MP, Lamonica CA. HIV-1 replication is controlled at the level of T cell activation and proviral integration. EMBO J 1990; 9:1551-60.
    • (1990) EMBO J , vol.9 , pp. 1551-1560
    • Stevenson, M.1    Stanwick, T.L.2    Dempsey, M.P.3    Lamonica, C.A.4
  • 9
    • 0025342694 scopus 로고
    • HIV-1 entry into quiescent primary lymphocytes: Molecular analysis reveals a labile, latent viral structure
    • Zack JA, Arrigo SJ, Weitsman SR, Go AS, Haislip A, Chen IS. HIV-1 entry into quiescent primary lymphocytes: molecular analysis reveals a labile, latent viral structure. Cell 1990; 61:213-22.
    • (1990) Cell , vol.61 , pp. 213-222
    • Zack, J.A.1    Arrigo, S.J.2    Weitsman, S.R.3    Go, A.S.4    Haislip, A.5    Chen, I.S.6
  • 10
    • 0031594498 scopus 로고    scopus 로고
    • Progression to the G1b phase of the cell cycle is required for completion of human immunodeficiency virus type 1 reverse transcription in T cells
    • Korin YD, Zack JA. Progression to the G1b phase of the cell cycle is required for completion of human immunodeficiency virus type 1 reverse transcription in T cells. J Virol 1998; 72:3161-8.
    • (1998) J Virol , vol.72 , pp. 3161-3168
    • Korin, Y.D.1    Zack, J.A.2
  • 11
    • 0022629524 scopus 로고
    • Long-term cultures of HTLV-III-infected T cells: A model of cytopathology of T-cell depletion in AIDS
    • Zagury D, Bernard J, Leonard R, et al. Long-term cultures of HTLV-III-infected T cells: a model of cytopathology of T-cell depletion in AIDS. Science 1986; 231:850-3.
    • (1986) Science , vol.231 , pp. 850-853
    • Zagury, D.1    Bernard, J.2    Leonard, R.3
  • 13
    • 15244351478 scopus 로고    scopus 로고
    • Divergent host responses during primary simian immunodeficiency virus SIVsm infection of natural sooty mangabey and nonnatural rhesus macaque hosts
    • Silvestri G, Fedanov A, Germon S, et al. Divergent host responses during primary simian immunodeficiency virus SIVsm infection of natural sooty mangabey and nonnatural rhesus macaque hosts. J Virol 2005; 79:4043-54.
    • (2005) J Virol , vol.79 , pp. 4043-4054
    • Silvestri, G.1    Fedanov, A.2    Germon, S.3
  • 14
    • 0037343278 scopus 로고    scopus 로고
    • Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia
    • Silvestri G, Sodora DL, Koup RA, et al. Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia. Immunity 2003; 18:441-52.
    • (2003) Immunity , vol.18 , pp. 441-452
    • Silvestri, G.1    Sodora, D.L.2    Koup, R.A.3
  • 15
    • 0031957164 scopus 로고    scopus 로고
    • Simian immunodeficiency virus replicates to high levels in sooty mangabeys without inducing disease
    • Rey-Cuille MA, Berthier JL, Bomsel-Demontoy MC, et al. Simian immunodeficiency virus replicates to high levels in sooty mangabeys without inducing disease. J Virol 1998; 72:3872-86.
    • (1998) J Virol , vol.72 , pp. 3872-3886
    • Rey-Cuille, M.A.1    Berthier, J.L.2    Bomsel-Demontoy, M.C.3
  • 16
    • 85047690906 scopus 로고    scopus 로고
    • Turnover of lymphocytes and conceptual paradigms in HIV infection
    • Silvestri G, Feinberg MB. Turnover of lymphocytes and conceptual paradigms in HIV infection. J Clin Invest 2003; 112:821-4.
    • (2003) J Clin Invest , vol.112 , pp. 821-824
    • Silvestri, G.1    Feinberg, M.B.2
  • 17
    • 9144261631 scopus 로고    scopus 로고
    • T-cell subsets that harbor human immunodeficiency virus (HIV) in vivo: Implications for HIV pathogenesis
    • Brenchley JM, Hill BJ, Ambrozak DR, et al. T-cell subsets that harbor human immunodeficiency virus (HIV) in vivo: implications for HIV pathogenesis. J Virol 2004; 78:1160-8.
    • (2004) J Virol , vol.78 , pp. 1160-1168
    • Brenchley, J.M.1    Hill, B.J.2    Ambrozak, D.R.3
  • 18
    • 0025255387 scopus 로고
    • Transmission of signals from the T lymphocyte antigen receptor to the genes responsible for cell proliferation and immune function: The missing link
    • Ullman KS, Northrop JP, Verweij CL, Crabtree GR. Transmission of signals from the T lymphocyte antigen receptor to the genes responsible for cell proliferation and immune function: the missing link. Annu Rev Immunol 1990; 8:421-52.
    • (1990) Annu Rev Immunol , vol.8 , pp. 421-452
    • Ullman, K.S.1    Northrop, J.P.2    Verweij, C.L.3    Crabtree, G.R.4
  • 19
    • 0036886239 scopus 로고    scopus 로고
    • Expansion of activated human naive T-cells precedes effector function
    • Brenchley JM, Douek DC, Ambrozak DR, et al. Expansion of activated human naive T-cells precedes effector function. Clin Exp Immunol 2002; 130:432-40.
    • (2002) Clin Exp Immunol , vol.130 , pp. 432-440
    • Brenchley, J.M.1    Douek, D.C.2    Ambrozak, D.R.3
  • 20
    • 0001585396 scopus 로고    scopus 로고
    • Control of homeostasis of CD8+ memory T cells by opposing cytokines
    • Ku CC, Murakami M, Sakamoto A, Kappler J, Marrack P. Control of homeostasis of CD8+ memory T cells by opposing cytokines. Science 2000; 288:675-8.
    • (2000) Science , vol.288 , pp. 675-678
    • Ku, C.C.1    Murakami, M.2    Sakamoto, A.3    Kappler, J.4    Marrack, P.5
  • 21
    • 18644376988 scopus 로고    scopus 로고
    • Spontaneous and homeostatic proliferation of CD4 T cells are regulated by different mechanisms
    • Min B, Yamane H, Hu-Li J, Paul WE. Spontaneous and homeostatic proliferation of CD4 T cells are regulated by different mechanisms. J Immunol 2005; 174:6039-44.
    • (2005) J Immunol , vol.174 , pp. 6039-6044
    • Min, B.1    Yamane, H.2    Hu-Li, J.3    Paul, W.E.4
  • 22
    • 17844374605 scopus 로고    scopus 로고
    • Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection
    • Mattapallil JJ, Douek DC, Hill B, Nishimura Y, Martin M, Roederer M. Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection. Nature 2005; 434:1093-7.
    • (2005) Nature , vol.434 , pp. 1093-1097
    • Mattapallil, J.J.1    Douek, D.C.2    Hill, B.3    Nishimura, Y.4    Martin, M.5    Roederer, M.6
  • 23
    • 0037032068 scopus 로고    scopus 로고
    • In patients on prolonged HAART, a significant pool of HIV infected CD4 T cells are HIV-specific
    • Demoustier A, Gubler B, Lambotte O, et al. In patients on prolonged HAART, a significant pool of HIV infected CD4 T cells are HIV-specific. AIDS 2002; 16:1749-54.
    • (2002) AIDS , vol.16 , pp. 1749-1754
    • Demoustier, A.1    Gubler, B.2    Lambotte, O.3
  • 24
    • 0037007670 scopus 로고    scopus 로고
    • HIV preferentially infects HIV-specific CD4+ T cells
    • Douek DC, Brenchley JM, Betts MR, et al. HIV preferentially infects HIV-specific CD4+ T cells. Nature 2002; 417:95-8.
    • (2002) Nature , vol.417 , pp. 95-98
    • Douek, D.C.1    Brenchley, J.M.2    Betts, M.R.3
  • 25
    • 0037103201 scopus 로고    scopus 로고
    • Analysis of HIV-1- and CMV-specific memory CD4 T-cell responses during primary and chronic infection
    • Harari A, Rizzardi GP, Ellefsen K, et al. Analysis of HIV-1- and CMV-specific memory CD4 T-cell responses during primary and chronic infection. Blood 2002; 100:1381-7.
    • (2002) Blood , vol.100 , pp. 1381-1387
    • Harari, A.1    Rizzardi, G.P.2    Ellefsen, K.3
  • 26
    • 0033534678 scopus 로고    scopus 로고
    • From TCR engagement to T cell activation: A kinetic view of T cell behavior
    • Lanzavecchia A, Lezzi G, Viola A. From TCR engagement to T cell activation: a kinetic view of T cell behavior. Cell 1999; 96:1-4.
    • (1999) Cell , vol.96 , pp. 1-4
    • Lanzavecchia, A.1    Lezzi, G.2    Viola, A.3
  • 27
    • 0031884839 scopus 로고    scopus 로고
    • The duration of antigenic stimulation determines the fate of naive and effector T cells
    • Iezzi G, Karjalainen K, Lanzavecchia A. The duration of antigenic stimulation determines the fate of naive and effector T cells. Immunity 1998; 8:89-95.
    • (1998) Immunity , vol.8 , pp. 89-95
    • Iezzi, G.1    Karjalainen, K.2    Lanzavecchia, A.3
  • 28
    • 0029851762 scopus 로고    scopus 로고
    • Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression
    • Timmerman LA, Clipstone NA, Ho SN, Northrop JP, Crabtree GR. Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression. Nature 1996; 383:837-40.
    • (1996) Nature , vol.383 , pp. 837-840
    • Timmerman, L.A.1    Clipstone, N.A.2    Ho, S.N.3    Northrop, J.P.4    Crabtree, G.R.5
  • 31
    • 0033942250 scopus 로고    scopus 로고
    • Effects of mycophenolic acid on human immunodeficiency virus infection in vitro and in vivo
    • Chapuis AG, Paolo Rizzardi G, D'Agostino C, et al. Effects of mycophenolic acid on human immunodeficiency virus infection in vitro and in vivo. Nat Med 2000; 6:762-8.
    • (2000) Nat Med , vol.6 , pp. 762-768
    • Chapuis, A.G.1    Paolo Rizzardi, G.2    D'Agostino, C.3
  • 33
    • 0023850621 scopus 로고
    • An in vivo study on the synchronizing effect of hydroxyurea
    • Maurer-Schultze B, Siebert M, Bassukas ID. An in vivo study on the synchronizing effect of hydroxyurea. Exp Cell Res 1988; 174:230-43.
    • (1988) Exp Cell Res , vol.174 , pp. 230-243
    • Maurer-Schultze, B.1    Siebert, M.2    Bassukas, I.D.3
  • 34
    • 0034654108 scopus 로고    scopus 로고
    • Mycophenolic acid-induced GTP depletion also affects ATP and pyrimidine synthesis in mitogen-stimulated primary human T-lymphocytes
    • Qiu Y, Fairbanks LD, Ruckermann K, et al. Mycophenolic acid-induced GTP depletion also affects ATP and pyrimidine synthesis in mitogen-stimulated primary human T-lymphocytes. Transplantation 2000; 69:890-7.
    • (2000) Transplantation , vol.69 , pp. 890-897
    • Qiu, Y.1    Fairbanks, L.D.2    Ruckermann, K.3
  • 35
    • 0031902991 scopus 로고    scopus 로고
    • In vivo pathogenesis of a human immunodeficiency virus type 1 reporter virus
    • Jamieson BD, Zack JA. In vivo pathogenesis of a human immunodeficiency virus type 1 reporter virus. J Virol 1998; 72:6520-6.
    • (1998) J Virol , vol.72 , pp. 6520-6526
    • Jamieson, B.D.1    Zack, J.A.2
  • 36
    • 0029165291 scopus 로고
    • The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2 + M phase of the cell cycle
    • Jowett JB, Planelles V, Poon B, Shah NP, Chen ML, Chen IS. The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2 + M phase of the cell cycle. J Virol 1995; 69:6304-13.
    • (1995) J Virol , vol.69 , pp. 6304-6313
    • Jowett, J.B.1    Planelles, V.2    Poon, B.3    Shah, N.P.4    Chen, M.L.5    Chen, I.S.6
  • 37
    • 0037374765 scopus 로고    scopus 로고
    • Commitment point during G0→G1 that controls entry into the cell cycle
    • Lea NC, Orr SJ, Stoeber K, et al. Commitment point during G0→G1 that controls entry into the cell cycle. Mol Cell Biol 2003; 23:2351-61.
    • (2003) Mol Cell Biol , vol.23 , pp. 2351-2361
    • Lea, N.C.1    Orr, S.J.2    Stoeber, K.3
  • 38
    • 20644439107 scopus 로고    scopus 로고
    • Soluble HIV-1 gp120 enhances HIV-1 replication in non-dividing CD4+ T cells, mediated via cell signaling and Tat cofactor overexpression
    • Misse D, Gajardo J, Oblet C, et al. Soluble HIV-1 gp120 enhances HIV-1 replication in non-dividing CD4+ T cells, mediated via cell signaling and Tat cofactor overexpression. AIDS 2005; 19:897-905.
    • (2005) AIDS , vol.19 , pp. 897-905
    • Misse, D.1    Gajardo, J.2    Oblet, C.3
  • 40
    • 0028880566 scopus 로고
    • Hydroxyurea and AIDS: An old drug finds a new application?
    • Lori F, Gallo RC. Hydroxyurea and AIDS: an old drug finds a new application? AIDS Res Hum Retroviruses 1995; 11:1149-51.
    • (1995) AIDS Res Hum Retroviruses , vol.11 , pp. 1149-1151
    • Lori, F.1    Gallo, R.C.2
  • 41
    • 0030831543 scopus 로고    scopus 로고
    • Combination of a drug targeting the cell with a drug targeting the virus controls human immunodeficiency virus type 1 resistance
    • Lori F, Malykh AG, Foli A, et al. Combination of a drug targeting the cell with a drug targeting the virus controls human immunodeficiency virus type 1 resistance. AIDS Res Hum Retroviruses 1997; 13:1403-9.
    • (1997) AIDS Res Hum Retroviruses , vol.13 , pp. 1403-1409
    • Lori, F.1    Malykh, A.G.2    Foli, A.3
  • 42
    • 0036092039 scopus 로고    scopus 로고
    • Control of HIV during a structured treatment interruption in chronically infected individuals with vigorous T cell responses
    • Lori F, Foli A, Maserati R, et al. Control of HIV during a structured treatment interruption in chronically infected individuals with vigorous T cell responses. HIV Clin Trials 2002; 3:115-24.
    • (2002) HIV Clin Trials , vol.3 , pp. 115-124
    • Lori, F.1    Foli, A.2    Maserati, R.3
  • 43
    • 33746866372 scopus 로고    scopus 로고
    • Immunomodulating Drugs for the Treatment of HIV/AIDS. September 9-10, 2004, Poiano, Italy. Abstracts. J Acquir Immune Defic Syndr 2006; 42(Suppl 1):S1-27.
    • Immunomodulating Drugs for the Treatment of HIV/AIDS. September 9-10, 2004, Poiano, Italy. Abstracts. J Acquir Immune Defic Syndr 2006; 42(Suppl 1):S1-27.
  • 44
    • 3042857765 scopus 로고    scopus 로고
    • Effect of mycophenolate mofetil on immune response and plasma and lymphatic tissue viral load during and after interruption of highly active antiretroviral therapy for patients with chronic HIV infection: A randomized pilot study
    • Garcia F, Plana M, Arnedo M, et al. Effect of mycophenolate mofetil on immune response and plasma and lymphatic tissue viral load during and after interruption of highly active antiretroviral therapy for patients with chronic HIV infection: a randomized pilot study. J Acquir Immune Defic Syndr 2004; 36:823-30.
    • (2004) J Acquir Immune Defic Syndr , vol.36 , pp. 823-830
    • Garcia, F.1    Plana, M.2    Arnedo, M.3
  • 45
    • 0037414987 scopus 로고    scopus 로고
    • A cytostatic drug improves control of HIV-1 replication during structured treatment interruptions: A randomized study
    • Garcia F, Plana M, Arnedo M, et al. A cytostatic drug improves control of HIV-1 replication during structured treatment interruptions: a randomized study. AIDS 2003; 17:43-51.
    • (2003) AIDS , vol.17 , pp. 43-51
    • Garcia, F.1    Plana, M.2    Arnedo, M.3
  • 46
    • 12144290358 scopus 로고    scopus 로고
    • Strategies to decrease viral load rebound, and prevent loss of CD4 and onset of resistance during structured treatment interruptions
    • Foli A, Maserati R, Barasolo G, et al. Strategies to decrease viral load rebound, and prevent loss of CD4 and onset of resistance during structured treatment interruptions. Antivir Ther 2004; 9:123-32.
    • (2004) Antivir Ther , vol.9 , pp. 123-132
    • Foli, A.1    Maserati, R.2    Barasolo, G.3
  • 47
    • 0642317064 scopus 로고    scopus 로고
    • The cell cycle, cyclin-dependent kinases, and viral infections: New horizons and unexpected connections
    • Schang LM. The cell cycle, cyclin-dependent kinases, and viral infections: new horizons and unexpected connections. Prog Cell Cycle Res 2003; 5:103-24.
    • (2003) Prog Cell Cycle Res , vol.5 , pp. 103-124
    • Schang, L.M.1


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