Technical considerations in longitudinal multispectral small animal molecular imaging

Journal of Biomedical Optics

Volumn 12, Issue 5, 2007, Pages

  Bouchard, Matthew B ^a   MacLaurin, Sarah A ^b   Dwyer, Peter J ^c   Mansfield, James ^c   Levenson, Richard ^c   Krucker, Thomas ^b  

^a NORTHEASTERN UNIVERSITY   (United States)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^c Cambridge Research & Instrumentation Inc   (United States)

Author keywords

Autofluorescence reduction; Multi spectral imaging; Spectral definition

Indexed keywords

ANIMAL; ARTICLE; ARTIFACT; BIOMEDICAL TECHNOLOGY ASSESSMENT; C57BL MOUSE; COMPUTER ASSISTED DIAGNOSIS; IMAGE ENHANCEMENT; MALE; METHODOLOGY; MOUSE; MULTIPHOTON MICROSCOPY; NUDE MOUSE; WHOLE BODY IMAGING;

ANIMALS; ARTIFACTS; IMAGE ENHANCEMENT; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MALE; MICE; MICE, INBRED C57BL; MICE, NUDE; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; TECHNOLOGY ASSESSMENT, BIOMEDICAL; WHOLE BODY IMAGING;

AUTOFLUORESCENCE REDUCTION; MOLECULAR IMAGING; MOUSE STRAINS; MULTI-SPECTRAL IMAGING; MULTISPECTRAL IMAGING SYSTEMS;

ANIMALS; FLUOROPHORES; IMAGING SYSTEMS; ROBUST CONTROL;

MEDICAL IMAGING;

ANIMALIA; MUS;

EID: 38449092653     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.2799188     Document Type: Article

References (29)

1. J. A. DiMasi, R. W. Hansen, and H. G. Grabowski, "The price of innovation: New estimates of drug development costs," J. Health Econ. 22(2), 151-185 (2003). (Pubitemid 36279392)
2. C. P. Adams and V. V. Brantner, "Estimating the cost of new drug development: Is it really 802 million dollars?," Health Aff (Millwood) 25(2), 420-428 (2006). (Pubitemid 43529550)
3. J. Drews, "Drug discovery: A historical perspective," Science 287(5460), 1960-1964 (2000). (Pubitemid 30158662)
4. C. Debouck and P. N. Goodfellow, "DNA microarrays in drug discovery and development," Nat. Genet. 21(1 Suppl), 48-50 (1999). (Pubitemid 29031492)
5. SMI, "The Society for Molecular Imaging, presented at the Fifth Annual Meeting of the Society for Molecular Imaging 2006, Waikoloa, Hawaii.
6. M. Rudin and R. Weissleder, "Molecular imaging in drug discovery and development," Nat. Rev. Drug Discovery 2(2), 123-131 (2003). (Pubitemid 37361644)
7. X. Gao, Y. Cui, R. M. Levenson, L. W. Chung, and S. Nie, "In vivo cancer targeting and imaging with semiconductor quantum dots," Nat. Biotechnol. 22(8), 969-976 (2004). (Pubitemid 39014473)
8. R. Weissleder and V. Ntziachristos, "Shedding light onto live molecular targets," Nat. Med. 9(1), 123-128 (2003). (Pubitemid 36098273)
9. B. W. Rice, M. D. Cable, and M. B. Nelson, "In vivo imaging of light-emitting probes," J. Biomed. Opt. 6(4), 432-440 (2001). (Pubitemid 34220962)
10. P. R. Contag, I. N. Olomu, D. K. Stevenson, and C. H. Contag, "Bioluminescent indicators in living mammals," Nat. Med. 4(2), 245-247 (1998). (Pubitemid 28137381)
11. D. Huang et al., "Optical coherence tomography," Science 254(5035), 1178-1181 (1991). (Pubitemid 21917444)
12. J. R. Mansfield and R. M. Levenson, "Distinguished photons: The MaestroTM in-vivo Fluorescence Imaging System," BioTechniques Protocol Guide 2006 (2007), pp. 49-62.
13. J. R. Mansfield, C. C. Hoyt, P. J. Miller, and R. M. Levenson, "Distinguished photons: Increased contrast with multispectral in-vivo fluorescence imaging," BioTechniques 39 (Suppl.), S25-S29 (2005).
14. T. Troy, D. Jekic-McMullen, L. Sambucetti, and B. Rice, "Quantitative comparison of the sensitivity of detection of fluorescent and bioluminescent reporters in animal models," Mol. Imaging 3(1), 9-23 (2004).
15. P. J. Miller and C. C. Hoyt, "Multispectral imaging with a liquid crystal tunable filter," Proc. SPIE 2345, 354-365 (1995).
16. G. Bearman and R. Levenson, Biological Imaging Spectroscopy, CRC Press, Boca Raton, FL (2003).
17. G. Zavattini, S. Vecchi, G. Mitchell, U. Weisser, R. M. Leahy, B. J. Pichler, D. J. Smith, and S. R. Cherry, "A hyperspectral fluorescence system for 3D in vivo optical imaging," Phys. Med. Biol. 51(8), 2029-2043 (2006).
18. S. Tominaga, "Spectral imaging by a multichannel camera," J. Electron. Imaging 8(4), 332-341 (1999). (Pubitemid 129512338)
19. J. M. Tam, R. Upadhyay, M. J. Pittet, R. Weissleder, and U. Mahmood, "Improved in vivo whole animal detection limits of GFPexpressing tumor lines by spectral fluorescence imaging," Mol. Imaging 5(3), Abstract 231, 244 (2006).
20. T. Zimmermann, J. Rietdorf, A. Girod, V. Georget, and R. Pepperkok, "Spectral imaging and linear un-mixing enables improved FRET efficiency with a novel GFP2-VFP FRET pair," FEBS Lett. 531(2), 245-249 (2002). (Pubitemid 35341202)
21. R. Lansford, G. Bearman, and S. E. Fraser, "Resolution of multiple green fluorescent protein color variants and dyes using two-photon microscopy and imaging spectroscopy," J. Biomed. Opt. 6(3), 311-318 (2001). (Pubitemid 32863914)
22. D. L. Farkas, C. Du, G. W. Fisher, C. Lau, W. Niu, E. S. Wachman, and R. M. Levenson, "Non-invasive image acquisition and advanced processing in optical bioimaging," Comput. Med. Imaging Graph. 22(2), 89-102 (1998). (Pubitemid 28400198)
23. S. A. MacLaurin, M. Bouchard, P. Dwyer, R. Levenson, J. Mansfield, and T. Krucker, "Reduction of skin and food autofluorescence in different mouse strains through diet changes," Mol. Imaging 5(3), Abstract 523, 252 (2006).
24. G. Weagle, P. E. Paterson, J. Kennedy, and R. Pottier, "The nature of the chromophore responsible for naturally occurring fluorescence in mouse skin," J. Photochem. Photobiol., B 2(3), 313-320 (1988).
25. H. R. Morris, C. C. Hoyt, and P. J. Treado, "Imaging spectrometers for fluorescence and raman microscopy: Acousto-optic and liquid crystal tunable filters," Appl. Spectrosc. 48(7), 857-866 (1994).
26. M. E. Winter, "N-FINDR: An algorithm for fast autonomous spectral end-member determination in hyperspectral data," Proc. SPIE 3753, 266-275 (1999).
27. J. R. Mansfield, K. W. Gossage, C. C. Hoyt, and R. M. Levenson, "Autofluorescence removal, multiplexing, and automated analysis methods for in-vivo fluorescence imaging," J. Biomed. Opt. 10(4), 041207 (2005).
28. M. E. Dickinson, G. Bearman, S. Tille, R. Lansford, and S. E. Fraser, "Multispectral imaging and linear unmixing add a whole new dimension to laser scanning fluorescence microscopy," BioTechniques 31(6), 1272, 1274-1276, 1278, (2001).
29. T. Zimmermann, J. Rietdorf, and R. Pepperkok, "Spectral imaging and its applications in live cell microscopy," FEBS Lett. 546(1), 87-92 (2003). (Pubitemid 36782286)