-
1
-
-
0026508766
-
Measurement of thymidine replacement in patients with high grade gliomas, head and neck tumours, and high grade sarcomas after continuous intravenous infusions of 5-iododeoxyuridine
-
Cook JA, Glass J, Lebovics R, Bobo H, Pass H, DeLaney TF, Oldfield EH, Mitchell JB, Glatstein E, Goffman TE (1992) Measurement of thymidine replacement in patients with high grade gliomas, head and neck tumours, and high grade sarcomas after continuous intravenous infusions of 5-iododeoxyuridine. Cancer Res 52: 719-725
-
(1992)
Cancer Res
, vol.52
, pp. 719-725
-
-
Cook, J.A.1
Glass, J.2
Lebovics, R.3
Bobo, H.4
Pass, H.5
DeLaney, T.F.6
Oldfield, E.H.7
Mitchell, J.B.8
Glatstein, E.9
Goffman, T.E.10
-
2
-
-
0028019247
-
Treatment of locally advanced cancer of the head and neck with 5′-iododeoxyuridine and hyperfractionated radiation therapy: Measurement of cell labelling and thymidine replacement
-
Epstein AH, Lebovics RS, Goffman T, Teague D, Fuetsch ES, Glatstein E, Okunieff P, Cook JA (1994) Treatment of locally advanced cancer of the head and neck with 5′-iododeoxyuridine and hyperfractionated radiation therapy: measurement of cell labelling and thymidine replacement. J Natl Cancer Inst 86: 1775-1780
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 1775-1780
-
-
Epstein, A.H.1
Lebovics, R.S.2
Goffman, T.3
Teague, D.4
Fuetsch, E.S.5
Glatstein, E.6
Okunieff, P.7
Cook, J.A.8
-
3
-
-
0025327622
-
Enhancement of radiation damage in cellular DNA following unifilar substitution with iododeoxyuridine
-
Fornace Jr AJ, Dobson PP, Kinsella TJ (1990) Enhancement of radiation damage in cellular DNA following unifilar substitution with iododeoxyuridine. Int J Radiat Oncol Biol Phys 18: 873-878
-
(1990)
Int J Radiat Oncol Biol Phys
, vol.18
, pp. 873-878
-
-
Fornace Jr., A.J.1
Dobson, P.P.2
Kinsella, T.J.3
-
4
-
-
0029947035
-
The limiting radiosensitization of tumours by S-phase sensitisers
-
Fowler JF, Kinsella TJ (1996) The limiting radiosensitization of tumours by S-phase sensitisers. Br J Cancer 74(Suppl): S294-S298
-
(1996)
Br J Cancer
, vol.74
, Issue.SUPPL.
-
-
Fowler, J.F.1
Kinsella, T.J.2
-
5
-
-
0026530627
-
Long-term follow-up on National Cancer Institute phase I/II study of glioblastoma multiforme treated with iododeoxyuridine and hyperfractionated irradiation
-
Goffman TE, Dachowski LJ, Bobo H, Oldfield EH, Steinberg SM, Cook J, Mitchell JB, Katz D, Smith R, Glatstein E (1992) Long-term follow-up on National Cancer Institute phase I/II study of glioblastoma multiforme treated with iododeoxyuridine and hyperfractionated irradiation. J Clin Oncol 10: 264-268
-
(1992)
J Clin Oncol
, vol.10
, pp. 264-268
-
-
Goffman, T.E.1
Dachowski, L.J.2
Bobo, H.3
Oldfield, E.H.4
Steinberg, S.M.5
Cook, J.6
Mitchell, J.B.7
Katz, D.8
Smith, R.9
Glatstein, E.10
-
6
-
-
0034774382
-
Phase II study of pegylated liposomal doxorubicin (Caelyx™) in patients with inoperable, locally advanced squamous cell cancer of the head and neck
-
Harrington KJ, Lewanski CR, Northcote AD, Whittaker J, Vile RG, Peters AM, Stewart JSW (2001a) Phase II study of pegylated liposomal doxorubicin (Caelyx™) in patients with inoperable, locally advanced squamous cell cancer of the head and neck. Eur J Cancer 37: 2015-2022
-
(2001)
Eur J Cancer
, vol.37
, pp. 2015-2022
-
-
Harrington, K.J.1
Lewanski, C.R.2
Northcote, A.D.3
Whittaker, J.4
Vile, R.G.5
Peters, A.M.6
Stewart, J.S.W.7
-
7
-
-
0034060056
-
Liposomes as vehicles for targeted therapy of cancer. Part 1: Preclinical development
-
Harrington KJ, Lewanski CR, Stewart JSW (2000a) Liposomes as vehicles for targeted therapy of cancer. Part 1: Preclinical development. Clin Oncol (R Coll Radiol) 12: 2-15
-
(2000)
Clin Oncol (R Coll Radiol)
, vol.12
, pp. 2-15
-
-
Harrington, K.J.1
Lewanski, C.R.2
Stewart, J.S.W.3
-
8
-
-
0035127410
-
Effective targeting of solid tumours in patients with locally advanced cancers by radiolabelled pegylated liposomes
-
Harrington KJ, Mohammadtaghi S, Uster PS, Glass DM, Peters AM, Vile RG, Stewart JSW (2001b) Effective targeting of solid tumours in patients with locally advanced cancers by radiolabelled pegylated liposomes. Clin Cancer Res 7: 243-254
-
(2001)
Clin Cancer Res
, vol.7
, pp. 243-254
-
-
Harrington, K.J.1
Mohammadtaghi, S.2
Uster, P.S.3
Glass, D.M.4
Peters, A.M.5
Vile, R.G.6
Stewart, J.S.W.7
-
9
-
-
0034489252
-
Pegylated liposome encapsulated doxorubicin and cisplatin enhance the effect of radiotherapy in a tumour xenograft model
-
Harrington KJ, Rowlinson-Busza G, Syrigos KN, Peters AM, Uster PS, Vile RG, Stewart JSW (2000b) Pegylated liposome encapsulated doxorubicin and cisplatin enhance the effect of radiotherapy in a tumour xenograft model. Clin Cancer Res 6: 4939-4949
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4939-4949
-
-
Harrington, K.J.1
Rowlinson-Busza, G.2
Syrigos, K.N.3
Peters, A.M.4
Uster, P.S.5
Vile, R.G.6
Stewart, J.S.W.7
-
10
-
-
0033624061
-
Biodistribution and pharmacokinetics of 111 In-DTPA-labelled pegylated liposomes in a human tumour xenograft model: Implications for novel targetting strategies
-
Harrington KJ, Rowlinson-Busza G, Syrigos KN, Uster PS, Abra RM, Stewart JSW (2000c) Biodistribution and pharmacokinetics of 111 In-DTPA-labelled pegylated liposomes in a human tumour xenograft model: implications for novel targetting strategies. Br J Cancer 83: 232-238
-
(2000)
Br J Cancer
, vol.83
, pp. 232-238
-
-
Harrington, K.J.1
Rowlinson-Busza, G.2
Syrigos, K.N.3
Uster, P.S.4
Abra, R.M.5
Stewart, J.S.W.6
-
11
-
-
0033934575
-
Pegylated liposome encapsulated doxorubicin and cisplatin in the treatment of head and neck xenograft tumours
-
Harrington KJ, Rowlinson-Busza G, Uster PS, Stewart JS (2000d) Pegylated liposome encapsulated doxorubicin and cisplatin in the treatment of head and neck xenograft tumours. Cancer Chemother Pharmacol 46: 10-18
-
(2000)
Cancer Chemother Pharmacol
, vol.46
, pp. 10-18
-
-
Harrington, K.J.1
Rowlinson-Busza, G.2
Uster, P.S.3
Stewart, J.S.4
-
12
-
-
0030664417
-
Controlled trials of synchronous chemotherapy with radiotherapy in head and neck cancer: Overview of radiation morbidity
-
Henk JM (1997) Controlled trials of synchronous chemotherapy with radiotherapy in head and neck cancer: overview of radiation morbidity. Clin Oncol (R Coll Radiol) 9: 308-312
-
(1997)
Clin Oncol (R Coll Radiol)
, vol.9
, pp. 308-312
-
-
Henk, J.M.1
-
13
-
-
0026733476
-
Microscopic localisation of sterically stabilised liposomes in colon carcinoma-bearing mice
-
Huang SK, Lee K-D, Hong K, Friend DS, Papahadjopoulos D (1992) Microscopic localisation of sterically stabilised liposomes in colon carcinoma-bearing mice. Cancer Res 52: 5135-5143
-
(1992)
Cancer Res
, vol.52
, pp. 5135-5143
-
-
Huang, S.K.1
Lee, K.-D.2
Hong, K.3
Friend, D.S.4
Papahadjopoulos, D.5
-
14
-
-
0024371774
-
Mechanism of radiosensitization by halogenated pyrimidines: Effect of BrdU on radiation induction of DNA and chromosome damage and its correlation with cell killing
-
Iliakis G, Kurtzman S, Pantelias G, Okayasu R (1989) Mechanism of radiosensitization by halogenated pyrimidines: effect of BrdU on radiation induction of DNA and chromosome damage and its correlation with cell killing. Radiat Res 119: 286-304
-
(1989)
Radiat Res
, vol.119
, pp. 286-304
-
-
Iliakis, G.1
Kurtzman, S.2
Pantelias, G.3
Okayasu, R.4
-
16
-
-
0032700799
-
Liposomal doxorubicin and conventionally fractionated radiotherapy in the treatment of locally advanced non-small-cell lung cancer and head and neck cancer
-
Koukourakis MI, Koukouraki S, Giatromanolaki A, Archimandritis SC, Skarlatos J, Beroukas K, Bizakis JG, Retails G, Karkavitsas N, Helidonis ES (1999) Liposomal doxorubicin and conventionally fractionated radiotherapy in the treatment of locally advanced non-small-cell lung cancer and head and neck cancer. J Clin Oncol 17: 3512-3521
-
(1999)
J Clin Oncol
, vol.17
, pp. 3512-3521
-
-
Koukourakis, M.I.1
Koukouraki, S.2
Giatromanolaki, A.3
Archimandritis, S.C.4
Skarlatos, J.5
Beroukas, K.6
Bizakis, J.G.7
Retails, G.8
Karkavitsas, N.9
Helidonis, E.S.10
-
17
-
-
0025325880
-
The dependence of halogenated pyrimidine incorporation and radio-sensitization on the duration of drug exposure
-
Lawrence TS, Davis MA, Maybaum J, Stetson PL, Ensminger WD (1990) The dependence of halogenated pyrimidine incorporation and radio-sensitization on the duration of drug exposure. Int J Radiat Oncol Biol Phys 18: 1393-1398
-
(1990)
Int J Radiat Oncol Biol Phys
, vol.18
, pp. 1393-1398
-
-
Lawrence, T.S.1
Davis, M.A.2
Maybaum, J.3
Stetson, P.L.4
Ensminger, W.D.5
-
18
-
-
0026709880
-
The experimental and clinical rationale for the use of S-phase-specific radiosensitizers to overcome tumour cell repopulation
-
McGinn CJ, Kinsella TJ (1992) The experimental and clinical rationale for the use of S-phase-specific radiosensitizers to overcome tumour cell repopulation. Semin Oncol 4: 21-28
-
(1992)
Semin Oncol
, vol.4
, pp. 21-28
-
-
McGinn, C.J.1
Kinsella, T.J.2
-
19
-
-
0026633463
-
Radiosensitization by halogenated pyrimidines: I. Radiosensitization of human colon cancer cells by iododeoxyuridine
-
Miller EM, Fowler JF, Kinsella TJ (1992) Radiosensitization by halogenated pyrimidines: I. Radiosensitization of human colon cancer cells by iododeoxyuridine. Radiat Res 131: 81-89
-
(1992)
Radiat Res
, vol.131
, pp. 81-89
-
-
Miller, E.M.1
Fowler, J.F.2
Kinsella, T.J.3
-
20
-
-
0031055830
-
Phase II study of liposomal doxorubicin in refractory ovarian cancer: Antitumour activity and toxicity modification by liposomal encapsulation
-
Muggia FM, Hainsworth JD, Jeffers S, Miller P, Groshen S, Tan M, Roman L, Uziely B, Muderspach L, Garcia A, Burnett A, Greco FA, Morrow CP, Paradiso LJ, Liang LJ (1997) Phase II study of liposomal doxorubicin in refractory ovarian cancer: antitumour activity and toxicity modification by liposomal encapsulation. J Clin Oncol 15: 987-993
-
(1997)
J Clin Oncol
, vol.15
, pp. 987-993
-
-
Muggia, F.M.1
Hainsworth, J.D.2
Jeffers, S.3
Miller, P.4
Groshen, S.5
Tan, M.6
Roman, L.7
Uziely, B.8
Muderspach, L.9
Garcia, A.10
Burnett, A.11
Greco, F.A.12
Morrow, C.P.13
Paradiso, L.J.14
Liang, L.J.15
-
21
-
-
0028852938
-
An overview of randomised controlled trials of adjuvant chemotherapy in head and neck cancer
-
Munro AJ (1995) An overview of randomised controlled trials of adjuvant chemotherapy in head and neck cancer. Br J Cancer 71: 83-91
-
(1995)
Br J Cancer
, vol.71
, pp. 83-91
-
-
Munro, A.J.1
-
22
-
-
0031861021
-
Pegylated-liposomal doxorubicin versus doxorubicin, bleomycin and vincristine in the treatment of AIDS-related Kaposi's sarcoma: Results of a randomised phase III clinical trial
-
Northfelt DW, Dezube BJ, Thommes JA, Miller BJ, Fischl MA, Friedman-Kien A, Kaplan LD, Du Mond C, Mamelok RD, Henry DH (1998) Pegylated-liposomal doxorubicin versus doxorubicin, bleomycin and vincristine in the treatment of AIDS-related Kaposi's sarcoma: results of a randomised phase III clinical trial. J Clin Oncol 16: 2445-2451
-
(1998)
J Clin Oncol
, vol.16
, pp. 2445-2451
-
-
Northfelt, D.W.1
Dezube, B.J.2
Thommes, J.A.3
Miller, B.J.4
Fischl, M.A.5
Friedman-Kien, A.6
Kaplan, L.D.7
Du Mond, C.8
Mamelok, R.D.9
Henry, D.H.10
-
23
-
-
0031909654
-
Randomized double-blind phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma. Results of the Danish Head and Neck Cancer Study (DAHANCA) Protocol 5-85
-
Overgaard J, Hansen HS, Overgaard M, Bastholt L, Berthelsen A, Specht L, Lindelov B, Jorgensen KA (1998) Randomized double-blind phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma. Results of the Danish Head and Neck Cancer Study (DAHANCA) Protocol 5-85. Radiother Oncol 46: 135-146
-
(1998)
Radiother Oncol
, vol.46
, pp. 135-146
-
-
Overgaard, J.1
Hansen, H.S.2
Overgaard, M.3
Bastholt, L.4
Berthelsen, A.5
Specht, L.6
Lindelov, B.7
Jorgensen, K.A.8
-
24
-
-
0026352832
-
Sterically stabilised liposomes: Improvements in pharmacokinetics and anti-tumour therapeutic efficacy
-
Papahadjopoulos D, Allen TM, Gabizon A, Mayhew E, Matthay K, Huang SK, Lee KD, Woodle MC, Lasic DD, Redemann C, Martin FJ (1991) Sterically stabilised liposomes: improvements in pharmacokinetics and anti-tumour therapeutic efficacy. Proc Natl Acad Sci USA 88: 11460-11464
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 11460-11464
-
-
Papahadjopoulos, D.1
Allen, T.M.2
Gabizon, A.3
Mayhew, E.4
Matthay, K.5
Huang, S.K.6
Lee, K.D.7
Woodle, M.C.8
Lasic, D.D.9
Redemann, C.10
Martin, F.J.11
-
25
-
-
0034681783
-
Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: Three meta-analyses of updated individual data
-
Pignon JP, Bourhis J, Domengé C, Designé L (2000) Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. Lancet 355: 949-955
-
(2000)
Lancet
, vol.355
, pp. 949-955
-
-
Pignon, J.P.1
Bourhis, J.2
Domengé, C.3
Designé, L.4
-
26
-
-
0030959798
-
Treatment of advanced breast cancer with sterically stabilized liposomal doxorubicin: Results of a multicentre phase II trial
-
Ranson MR, Carmichael J, O'Byrne K, Stewart S, Smith D, Howell A (1997) Treatment of advanced breast cancer with sterically stabilized liposomal doxorubicin: results of a multicentre phase II trial. J Clin Oncol 15: 3185-3191
-
(1997)
J Clin Oncol
, vol.15
, pp. 3185-3191
-
-
Ranson, M.R.1
Carmichael, J.2
O'Byrne, K.3
Stewart, S.4
Smith, D.5
Howell, A.6
-
27
-
-
0028833270
-
Preoperative radiation therapy and iododeoxyuridine for large retroperitoneal sarcomas
-
Robertson JM, Sondak VK, Weiss SA, Sussman JJ, Chang AE, Lawrence TS (1995) Preoperative radiation therapy and iododeoxyuridine for large retroperitoneal sarcomas. Int J Radiat Oncol Biol Phys 31: 87-92
-
(1995)
Int J Radiat Oncol Biol Phys
, vol.31
, pp. 87-92
-
-
Robertson, J.M.1
Sondak, V.K.2
Weiss, S.A.3
Sussman, J.J.4
Chang, A.E.5
Lawrence, T.S.6
-
28
-
-
0029976702
-
Clinical results of hypoxic cell radiosensitization from hyperbaric oxygen to accelerated radiotherapy, carbogen and nicotinamide
-
Saunders M, Dische S (1996) Clinical results of hypoxic cell radiosensitization from hyperbaric oxygen to accelerated radiotherapy, carbogen and nicotinamide. Br J Cancer 74: S271-S278
-
(1996)
Br J Cancer
, vol.74
-
-
Saunders, M.1
Dische, S.2
-
29
-
-
0023815533
-
Selective incorporation of iododeoxyuridine into DNA of hepatic metastases versus normal human liver
-
Speth PA, Kinsella TJ, Chang AE, Klecker RW, Belanger K, Collins JM (1988) Selective incorporation of iododeoxyuridine into DNA of hepatic metastases versus normal human liver. Clin Pharmacol Ther 44: 369-375
-
(1988)
Clin Pharmacol Ther
, vol.44
, pp. 369-375
-
-
Speth, P.A.1
Kinsella, T.J.2
Chang, A.E.3
Klecker, R.W.4
Belanger, K.5
Collins, J.M.6
-
30
-
-
0031941991
-
Randomised comparative trial of pegylated liposomal doxorubicin versus bleomycin and vincristine in the treatment of AIDS-related Kaposi's sarcoma
-
International Pegylated Liposomal Doxorubicin Study Group
-
Stewart S, Jablonowski H, Goebel F-D, Arasteh K, Spittle M, Rios A, Aboulafia D, Galleshaw J, Dezube BJ (1998) Randomised comparative trial of pegylated liposomal doxorubicin versus bleomycin and vincristine in the treatment of AIDS-related Kaposi's sarcoma. International Pegylated Liposomal Doxorubicin Study Group. J Clin Oncol 16: 683-691
-
(1998)
J Clin Oncol
, vol.16
, pp. 683-691
-
-
Stewart, S.1
Jablonowski, H.2
Goebel, F.-D.3
Arasteh, K.4
Spittle, M.5
Rios, A.6
Aboulafia, D.7
Galleshaw, J.8
Dezube, B.J.9
-
31
-
-
0028021915
-
National Cancer Institute (Phase II) study of high-grade glioma treated with accelerated hyperfractionated radiation and iododeoxyuridine: Results in anaplastic astrocytoma
-
Sullivan FJ, Herscher LL, Cook JA, Smith J, Steinberg SM, Epstein AH, Oldfield EH, Goffman TE, Kinsella TJ, Mitchell JB (1994) National Cancer Institute (Phase II) study of high-grade glioma treated with accelerated hyperfractionated radiation and iododeoxyuridine: results in anaplastic astrocytoma. Int J Radiat Oncol Biol Phys 30: 583-590
-
(1994)
Int J Radiat Oncol Biol Phys
, vol.30
, pp. 583-590
-
-
Sullivan, F.J.1
Herscher, L.L.2
Cook, J.A.3
Smith, J.4
Steinberg, S.M.5
Epstein, A.H.6
Oldfield, E.H.7
Goffman, T.E.8
Kinsella, T.J.9
Mitchell, J.B.10
-
32
-
-
0029954120
-
Treatment of cancer with radiation and drugs
-
Tannock IF (1996) Treatment of cancer with radiation and drugs. J Clin Oncol 14: 3156-3174
-
(1996)
J Clin Oncol
, vol.14
, pp. 3156-3174
-
-
Tannock, I.F.1
-
33
-
-
0027490744
-
Iododeoxyuridine (IUdR) combined with radiation in the treatment of malignant glioma: A comparison of short versus long intravenous dose schedules (RTOG 86-12)
-
Urtasun RC, Cosmatos D, DelRowe J, Kinsella TJ, Lester S, Wasserman T, Fulton DS (1993) Iododeoxyuridine (IUdR) combined with radiation in the treatment of malignant glioma: a comparison of short versus long intravenous dose schedules (RTOG 86-12). Int J Radiat Oncol Biol Phys 27: 207-214
-
(1993)
Int J Radiat Oncol Biol Phys
, vol.27
, pp. 207-214
-
-
Urtasun, R.C.1
Cosmatos, D.2
DelRowe, J.3
Kinsella, T.J.4
Lester, S.5
Wasserman, T.6
Fulton, D.S.7
-
34
-
-
17744417493
-
Survival improvement in anaplastic astrocytoma, combining external radiation with halogenated pyrimidines: Final report of RTOG 86-12, phase I-II study
-
Urtasun RC, Kinsella TJ, Farnan N, DelRowe JD, Lester SG, Fulton DS (1996) Survival improvement in anaplastic astrocytoma, combining external radiation with halogenated pyrimidines: final report of RTOG 86-12, phase I-II study. Int J Radiat Oncol Biol Phys 36: 1163-1167
-
(1996)
Int J Radiat Oncol Biol Phys
, vol.36
, pp. 1163-1167
-
-
Urtasun, R.C.1
Kinsella, T.J.2
Farnan, N.3
DelRowe, J.D.4
Lester, S.G.5
Fulton, D.S.6
-
35
-
-
16744368637
-
United Kingdom Co-ordinating Committee on Cancer Research (UKCCCR) Guidelines for the Welfare of Animals in Experimental Neoplasia (2nd edn)
-
Workman P, Twentyman P, Balkwill F, Balmain A, Chaplin D, Double J, Embleton J, Newell D, Raymond R, Stables J, Stephens T, Wallace J (1998) United Kingdom Co-ordinating Committee on Cancer Research (UKCCCR) Guidelines for the Welfare of Animals in Experimental Neoplasia (2nd edn). Br J Cancer 77: 1-10
-
(1998)
Br J Cancer
, vol.77
, pp. 1-10
-
-
Workman, P.1
Twentyman, P.2
Balkwill, F.3
Balmain, A.4
Chaplin, D.5
Double, J.6
Embleton, J.7
Newell, D.8
Raymond, R.9
Stables, J.10
Stephens, T.11
Wallace, J.12
-
36
-
-
0024845413
-
3,4 Dinitrophenyl N-acetyl -β-D-glucosaminide, a synthetic substrate for direct spectrophotometric assay of N-acetyl-β-D-glucosaminidase or N-acetyl-β-D-hexosaminidase
-
Yagi T, Hisada R, Shibata H (1989) 3,4 Dinitrophenyl N-acetyl -β-D-glucosaminide, a synthetic substrate for direct spectrophotometric assay of N-acetyl-β-D-glucosaminidase or N-acetyl-β-D-hexosaminidase. Anal Biochem 183: 245-249
-
(1989)
Anal Biochem
, vol.183
, pp. 245-249
-
-
Yagi, T.1
Hisada, R.2
Shibata, H.3
|