-
1
-
-
0034958947
-
Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
-
Angus D.C., Linde-Zwirble W.T., Lidicker J., Clermont G., Carcillo J., Pinsky M.R. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med. 29:2001;1303-1310
-
(2001)
Crit Care Med
, vol.29
, pp. 1303-1310
-
-
Angus, D.C.1
Linde-Zwirble, W.T.2
Lidicker, J.3
Clermont, G.4
Carcillo, J.5
Pinsky, M.R.6
-
2
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak A., He X., Smirnova I., Liu M.Y., Van Huffel C., Du X., et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science. 282:1998;2085-2088
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
Van Huffel, C.5
Du, X.6
-
3
-
-
0033120081
-
Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product
-
Hoshino K., Takeuchi O., Kawai T., Sanjo H., Ogawa T., Takeda Y., et al. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J Immunol. 162:1999;3749-3752
-
(1999)
J Immunol
, vol.162
, pp. 3749-3752
-
-
Hoshino, K.1
Takeuchi, O.2
Kawai, T.3
Sanjo, H.4
Ogawa, T.5
Takeda, Y.6
-
5
-
-
0026016470
-
Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomized, double-blind, placebo-controlled trial. The HA-1A Sepsis Study Group
-
Ziegler E.J., Fisher C.J. Jr., Sprung C.L., Straube R.C., Sadoff J.C., Foulke G.E., et al. Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomized, double-blind, placebo-controlled trial. The HA-1A Sepsis Study Group. N Engl J Med. 324:1991;429-436
-
(1991)
N Engl J Med
, vol.324
, pp. 429-436
-
-
Ziegler, E.J.1
Fisher Jr., C.J.2
Sprung, C.L.3
Straube, R.C.4
Sadoff, J.C.5
Foulke, G.E.6
-
6
-
-
0025917510
-
A controlled clinical trial of E5 murine monoclonal IgM antibody to endotoxin in the treatment of gram-negative sepsis. The XOMA Sepsis Study Group
-
Greenman R.L., Schein R.M., Martin M.A., Wenzel R.P., MacIntyre N.R., Emmanuel G., et al. A controlled clinical trial of E5 murine monoclonal IgM antibody to endotoxin in the treatment of gram-negative sepsis. The XOMA Sepsis Study Group. JAMA. 266:1991;1097-1102
-
(1991)
JAMA
, vol.266
, pp. 1097-1102
-
-
Greenman, R.L.1
Schein, R.M.2
Martin, M.A.3
Wenzel, R.P.4
MacIntyre, N.R.5
Emmanuel, G.6
-
7
-
-
0034675328
-
Recombinant bactericidal/permeability-increasing protein (rBPI21) as adjunctive treatment for children with severe meningococcal sepsis: A randomised trial. rBPI21 Meningococcal Sepsis Study Group
-
Levin M., Quint P.A., Goldstein B., Barton P., Bradley J.S., Shemie S.D., et al. Recombinant bactericidal/permeability-increasing protein (rBPI21) as adjunctive treatment for children with severe meningococcal sepsis: a randomised trial. rBPI21 Meningococcal Sepsis Study Group. Lancet. 356:2000;961-967
-
(2000)
Lancet
, vol.356
, pp. 961-967
-
-
Levin, M.1
Quint, P.A.2
Goldstein, B.3
Barton, P.4
Bradley, J.S.5
Shemie, S.D.6
-
8
-
-
0022655561
-
Physiological effects of a bactericidal protein from human polymorphonuclear leukocytes on Pseudomonas aeruginosa
-
Hovde C.J., Gray B.H. Physiological effects of a bactericidal protein from human polymorphonuclear leukocytes on Pseudomonas aeruginosa. Infect Immun. 52:1986;90-95
-
(1986)
Infect Immun
, vol.52
, pp. 90-95
-
-
Hovde, C.J.1
Gray, B.H.2
-
9
-
-
0032007337
-
Role of the bactericidal/permeability-increasing protein in host defence
-
Elsbach P., Weiss J. Role of the bactericidal/permeability-increasing protein in host defence. Curr Opin Immunol. 10:1998;45-49
-
(1998)
Curr Opin Immunol
, vol.10
, pp. 45-49
-
-
Elsbach, P.1
Weiss, J.2
-
10
-
-
0028225343
-
Bactericidal activity of synthetic peptides based on the structure of the 55-kilodalton bactericidal protein from human neutrophils
-
Gray B.H., Haseman J.R. Bactericidal activity of synthetic peptides based on the structure of the 55-kilodalton bactericidal protein from human neutrophils. Infect Immun. 62:1994;2732-2739
-
(1994)
Infect Immun
, vol.62
, pp. 2732-2739
-
-
Gray, B.H.1
Haseman, J.R.2
-
11
-
-
0030760314
-
Crystal structure of human BPI and two bound phospholipids at 2.4 angstrom resolution
-
Beamer L.J., Carroll S.F., Eisenberg D. Crystal structure of human BPI and two bound phospholipids at 2.4 angstrom resolution. Science. 276:1997;1861-1864
-
(1997)
Science
, vol.276
, pp. 1861-1864
-
-
Beamer, L.J.1
Carroll, S.F.2
Eisenberg, D.3
-
12
-
-
0029087339
-
Peptide derivatives of three distinct lipopolysaccharide binding proteins inhibit lipopolysaccharide-induced tumor necrosis factor-alpha secretion in vitro
-
Battafarano R.J., Dahlberg P.S., Ratz C.A., Johnston J.W., Gray B.H., Haseman J.R., et al. Peptide derivatives of three distinct lipopolysaccharide binding proteins inhibit lipopolysaccharide-induced tumor necrosis factor-alpha secretion in vitro. Surgery. 118:1995;318-324
-
(1995)
Surgery
, vol.118
, pp. 318-324
-
-
Battafarano, R.J.1
Dahlberg, P.S.2
Ratz, C.A.3
Johnston, J.W.4
Gray, B.H.5
Haseman, J.R.6
-
13
-
-
0029044454
-
B/PI-derived synthetic peptides: Synergistic effects in tethered bactericidal and endotoxin neutralizing peptides
-
Gray B.H., Haseman J.R., Mayo K.H. B/PI-derived synthetic peptides: synergistic effects in tethered bactericidal and endotoxin neutralizing peptides. Biochim Biophys Acta. 1244:1995;185-190
-
(1995)
Biochim Biophys Acta
, vol.1244
, pp. 185-190
-
-
Gray, B.H.1
Haseman, J.R.2
Mayo, K.H.3
-
15
-
-
0034620528
-
Rational modification of protein stability by the mutation of charged surface residues
-
Spector, S, Wang M, Carp SA, Robblee J, Hendsch AS, Fairman R, et al. Rational modification of protein stability by the mutation of charged surface residues. Biochemistry 39:872-9.
-
Biochemistry
, vol.39
, pp. 872-879
-
-
Spector, S.1
Wang, M.2
Carp, S.A.3
Robblee, J.4
Hendsch, A.S.5
Fairman, R.6
-
16
-
-
0035281805
-
Anginex, a designed peptide that inhibits angiogenesis
-
Griffioen A.W., van der Schaft D.W.J., Barendsz-Janson A.F., Cox A., Struijker Boudier H.A.J., Hillen H.F.P., et al. Anginex, a designed peptide that inhibits angiogenesis. Biochem J. 354:2001;233-245
-
(2001)
Biochem J
, vol.354
, pp. 233-245
-
-
Griffioen, A.W.1
Van Der Schaft, D.W.J.2
Barendsz-Janson, A.F.3
Cox, A.4
Struijker Boudier, H.A.J.5
Hillen, H.F.P.6
-
17
-
-
0035675008
-
Designed β-sheet peptides that inhibit proliferation and induce apoptosis in endothelial cells
-
Mayo K.H., van der Schaft D.W.J., Griffioen A.W. Designed β-sheet peptides that inhibit proliferation and induce apoptosis in endothelial cells. Angiogenesis. 4:2001;45-51
-
(2001)
Angiogenesis
, vol.4
, pp. 45-51
-
-
Mayo, K.H.1
Van Der Schaft, D.W.J.2
Griffioen, A.W.3
-
18
-
-
0028020765
-
Protective effects of an N-terminal fragment of bactericidal/ permeability-increasing protein in rodent models of gram-negative sepsis: Role of bactericidal properties
-
Ammons W.S., Kohn F.R., Kung A.H. Protective effects of an N-terminal fragment of bactericidal/permeability-increasing protein in rodent models of gram-negative sepsis: role of bactericidal properties. J Infect Dis. 170:1994;1473-1482
-
(1994)
J Infect Dis
, vol.170
, pp. 1473-1482
-
-
Ammons, W.S.1
Kohn, F.R.2
Kung, A.H.3
-
19
-
-
0029385205
-
23) decreases Escherichia coli-induced mortality and organ injury during immunosuppression-related neutropenia
-
23) decreases Escherichia coli-induced mortality and organ injury during immunosuppression-related neutropenia. Shock. 4:1995;298-306
-
(1995)
Shock
, vol.4
, pp. 298-306
-
-
Lechner, A.J.1
Lamprech, K.E.2
Johanns, C.A.3
Matuschak, G.M.4
-
20
-
-
0032538127
-
Designed beta-sheet-forming peptide 33mers with potent human bactericidal/permeability increasing protein-like bactericidal and endotoxin neutralizing activities
-
Mayo K.H., Haseman J., Ilyina E., Gray B. Designed beta-sheet-forming peptide 33mers with potent human bactericidal/permeability increasing protein-like bactericidal and endotoxin neutralizing activities. Biochim Biophys Acta. 1425:1998;81-92
-
(1998)
Biochim Biophys Acta
, vol.1425
, pp. 81-92
-
-
Mayo, K.H.1
Haseman, J.2
Ilyina, E.3
Gray, B.4
-
21
-
-
12644278299
-
Design of a potent novel endotoxin antagonist
-
Uknis M.E., Wasiluk K.R., Acton R.D., Klaerner H.G., Dahlberg P.S., Ilyina E.E., et al. Design of a potent novel endotoxin antagonist. Surgery. 122:1997;380-385
-
(1997)
Surgery
, vol.122
, pp. 380-385
-
-
Uknis, M.E.1
Wasiluk, K.R.2
Acton, R.D.3
Klaerner, H.G.4
Dahlberg, P.S.5
Ilyina, E.E.6
-
22
-
-
0036884619
-
The designer anti-angiogenic peptide anginex targets tumor endothelial cells and inhibits tumor growth in animal models
-
van der Schaft D.W.J., Dings R.P.M., De Lussanet Q.G., van Eijk L.I., Nap A.W., Beets-Tam R.G.H., et al. The designer anti-angiogenic peptide anginex targets tumor endothelial cells and inhibits tumor growth in animal models. FASEB J. 16:2002;1991-1993
-
(2002)
FASEB J
, vol.16
, pp. 1991-1993
-
-
Van Der Schaft, D.W.J.1
Dings, R.P.M.2
De Lussanet, Q.G.3
Van Eijk, L.I.4
Nap, A.W.5
Beets-Tam, R.G.H.6
-
23
-
-
0038343115
-
Beta-sheet is the bioactive conformation of the anti-angiogenic anginex peptide
-
Dings R.P., Arroyo M.M., Lockwood N.A., van Eijk L.I., Haseman J.R., Griffioen A.W., et al. Beta-sheet is the bioactive conformation of the anti-angiogenic anginex peptide. Biochem J. 373:2003;281-288
-
(2003)
Biochem J
, vol.373
, pp. 281-288
-
-
Dings, R.P.1
Arroyo, M.M.2
Lockwood, N.A.3
Van Eijk, L.I.4
Haseman, J.R.5
Griffioen, A.W.6
|