Inhibition of the tumor necrosis factor-α-converting enzyme by its pro domain

Journal of Biological Chemistry

Volumn 279, Issue 30, 2004, Pages 31638-31645

  Gonzales, Patricia E ^a   Solomon, Ariel ^b   Miller, Ann B ^c   Leesnitzer, M Anthony ^c   Sagis, Irit ^c   Milla, Marcos E ^a,d  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^c GLAXOSMITHKLINE   (United States)

^d 242 Anatomy Chemistry Bldg ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; BINDING ENERGY; BIOSYNTHESIS; ENZYME INHIBITION; MICROWAVE ISOLATORS; SPECTROSCOPIC ANALYSIS; TUMORS;

ISOLATION; TUMOR NECROSIS FACTOR-Α-CONVERTING ENZYME (TACE); ZINC CATALYSIS;

ENZYMES;

CYSTEINE; DISINTEGRIN; ENZYME PRECURSOR; METALLOPROTEINASE; PROTEINASE; SULFUR; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME;

ARTICLE; CATALYSIS; CONCENTRATION RESPONSE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; IC 50; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; WILD TYPE; X RAY SPECTROMETRY;

ADAM PROTEINS; AMINO ACID SEQUENCE; ANIMALS; CATALYTIC DOMAIN; CYSTEINE; METALLOENDOPEPTIDASES; MUTAGENESIS, SITE-DIRECTED; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 3843096112     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M401311200     Document Type: Article

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