-
1
-
-
0036189831
-
-
Agerso H, Jensen LB, Elbrond B eL al (2002) The pharmacokinetics, pharmacodynamics, safety and tolerability of NN2211, a new long-acting GLP-1 derivative, in healthy men. Diabetologia 45:195-202
-
Agerso H, Jensen LB, Elbrond B eL al (2002) The pharmacokinetics, pharmacodynamics, safety and tolerability of NN2211, a new long-acting GLP-1 derivative, in healthy men. Diabetologia 45:195-202
-
-
-
-
2
-
-
34447649668
-
DPP-4 Inhibitors - Clinical Data and Clinical Implications
-
Epub ahead of print
-
Ahren B (2007) DPP-4 Inhibitors - Clinical Data and Clinical Implications. Diabetes Care [Epub ahead of print]
-
(2007)
Diabetes Care
-
-
Ahren, B.1
-
3
-
-
33845472504
-
Effect of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy on glycemic control in patients with type 2 diabetes
-
Aschner P, Kipnes MS, Lunceford JK et al (2006) Effect of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy on glycemic control in patients with type 2 diabetes. Diabetes Care 29: 2632-7
-
(2006)
Diabetes Care
, vol.29
, pp. 2632-2637
-
-
Aschner, P.1
Kipnes, M.S.2
Lunceford, J.K.3
-
4
-
-
38349159137
-
DPP-4 inhibition improves insulin resistance (IR) in type 2 diabetes mellitus
-
9-13 June, Washington, DC. Abstract 5-LB
-
Azuma K, Radikova Z, Mancino JM et al (2006) DPP-4 inhibition improves insulin resistance (IR) in type 2 diabetes mellitus. Program and abstracts of the American Diabetes Association 66th Scientific Sessions, 9-13 June 2006, Washington, DC. Abstract 5-LB
-
(2006)
Program and abstracts of the American Diabetes Association 66th Scientific Sessions
-
-
Azuma, K.1
Radikova, Z.2
Mancino, J.M.3
-
5
-
-
7444228521
-
Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulphonylurea treated patients with type 2 diabetes
-
Buse JB, Henry RR, Han J et al (2004) Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulphonylurea treated patients with type 2 diabetes. Diabetes Care 27: 2628-35
-
(2004)
Diabetes Care
, vol.27
, pp. 2628-2635
-
-
Buse, J.B.1
Henry, R.R.2
Han, J.3
-
6
-
-
38349141439
-
Restoration of an acute insulin response to glucose (AIRg) in drug-naïve patients with type 2 diabetes by 3-month treatment with vildagliptin
-
9-13 June, Washington, DC. Abstract 454-P
-
D'Alessio DA, Watson CE, He Y-L et al (2006) Restoration of an acute insulin response to glucose (AIRg) in drug-naïve patients with type 2 diabetes by 3-month treatment with vildagliptin. Program and abstracts of the American Diabetes Association 66th Scientific Sessions, 9-13 June 2006, Washington, DC. Abstract 454-P
-
(2006)
Program and abstracts of the American Diabetes Association 66th Scientific Sessions
-
-
D'Alessio, D.A.1
Watson, C.E.2
He, Y.-L.3
-
7
-
-
4344675057
-
Therapeutic strategies based on glucagon-like peptide 1
-
Deacon CF (2004) Therapeutic strategies based on glucagon-like peptide 1. Diabetes 3: 2181-9
-
(2004)
Diabetes
, vol.3
, pp. 2181-2189
-
-
Deacon, C.F.1
-
8
-
-
18144401971
-
Effects of exenatide (exendin-4) on glycemic control over 30 weeks in metformin-treated patients
-
DeFronzo RA, Ratner RE, Han J (2005) Effects of exenatide (exendin-4) on glycemic control over 30 weeks in metformin-treated patients. Diabetes Care 28:1092-100
-
(2005)
Diabetes Care
, vol.28
, pp. 1092-1100
-
-
DeFronzo, R.A.1
Ratner, R.E.2
Han, J.3
-
10
-
-
0034857141
-
Development of glucagon-like peptide-1-based pharmaceuticals as therapeutic agents for the treatment of diabetes
-
Drucker DJ (2001) Development of glucagon-like peptide-1-based pharmaceuticals as therapeutic agents for the treatment of diabetes. Current Pharmaceutical Design 7:1399-412
-
(2001)
Current Pharmaceutical Design
, vol.7
, pp. 1399-1412
-
-
Drucker, D.J.1
-
11
-
-
0037312818
-
Glucagon-like peptides: Regulators of cell proliferation, differentiation, and apoptosis
-
Drucker DJ (2003) Glucagon-like peptides: regulators of cell proliferation, differentiation, and apoptosis. Molecular Endocrinology 17:161-71
-
(2003)
Molecular Endocrinology
, vol.17
, pp. 161-171
-
-
Drucker, D.J.1
-
13
-
-
0025242054
-
Purification and structure of exendin-3, a new pancreatic secretagogue isolated from Heloderma horridum venom
-
Eng J, Andrews PC, Kleinman WA et al (1990) Purification and structure of exendin-3, a new pancreatic secretagogue isolated from Heloderma horridum venom. Journal of Biological Chemistry 265:20259-62
-
(1990)
Journal of Biological Chemistry
, vol.265
, pp. 20259-20262
-
-
Eng, J.1
Andrews, P.C.2
Kleinman, W.A.3
-
14
-
-
0026648961
-
Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas
-
Eng J, Kleiman WA, Singh L et al (1992) Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas. Journal of Biological Chemistry 267: 7402-5
-
(1992)
Journal of Biological Chemistry
, vol.267
, pp. 7402-7405
-
-
Eng, J.1
Kleiman, W.A.2
Singh, L.3
-
15
-
-
4644300651
-
Effectiveness of progressive dose-escalation of exenatide (exendin-4) in reducing dose-limiting side effects in subjects with type 2 diabetes
-
Fineman MS, Shen LZ, Taylor K et al (2004) Effectiveness of progressive dose-escalation of exenatide (exendin-4) in reducing dose-limiting side effects in subjects with type 2 diabetes. Diabetes/Metabolism Research and Reviews 20:411-17
-
(2004)
Diabetes/Metabolism Research and Reviews
, vol.20
, pp. 411-417
-
-
Fineman, M.S.1
Shen, L.Z.2
Taylor, K.3
-
16
-
-
38349106054
-
Vildagliptin as an add-on to insulin in patients with type 2 diabetes
-
9-13 June, Washington, DC. Abstract 467-P
-
Fonseca V, Dejager S, Albrecht D, Shirt L, Schweizer A (2006) Vildagliptin as an add-on to insulin in patients with type 2 diabetes. Program and abstracts of the American Diabetes Association 66th Scientific Sessions, 9-13 June 2006, Washington, DC. Abstract 467-P
-
(2006)
Program and abstracts of the American Diabetes Association 66th Scientific Sessions
-
-
Fonseca, V.1
Dejager, S.2
Albrecht, D.3
Shirt, L.4
Schweizer, A.5
-
17
-
-
33845468278
-
Dipeptidyl peptidase (DPP-IV) inhibitors: A newly emerging drug class for the treatment of type 2 diabetes
-
Green BD, Flatt PR, Bailey CJ (2006) Dipeptidyl peptidase (DPP-IV) inhibitors: a newly emerging drug class for the treatment of type 2 diabetes. Diabetes and Vascular Disease Research 3: 159-65
-
(2006)
Diabetes and Vascular Disease Research
, vol.3
, pp. 159-165
-
-
Green, B.D.1
Flatt, P.R.2
Bailey, C.J.3
-
18
-
-
26944477362
-
Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: A randomized trial
-
Heine RJ, Van Gaal LF, Johns D et al (2005) Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: a randomized trial. Annals of Internal Medicine 143: 559-69
-
(2005)
Annals of Internal Medicine
, vol.143
, pp. 559-569
-
-
Heine, R.J.1
Van Gaal, L.F.2
Johns, D.3
-
19
-
-
33846844912
-
Dipeptidyl peptidase-IV inhibitors: A major new class of oral antidiabetic drug
-
Idris I, Donnelly R (2007) Dipeptidyl peptidase-IV inhibitors: a major new class of oral antidiabetic drug. Diabetes, Obesity and Metabolism 9: 153-65
-
(2007)
Diabetes, Obesity and Metabolism
, vol.9
, pp. 153-165
-
-
Idris, I.1
Donnelly, R.2
-
20
-
-
0036066641
-
Bedtime administration of NN2211, a long-acting GLP-1 derivative, substantially reduces fasting and postprandial glycemia in type 2 diabetes
-
Juhl CB, Hollingdal M, Sturis J et al (2002) Bedtime administration of NN2211, a long-acting GLP-1 derivative, substantially reduces fasting and postprandial glycemia in type 2 diabetes. Diabetes 51: 424-9
-
(2002)
Diabetes
, vol.51
, pp. 424-429
-
-
Juhl, C.B.1
Hollingdal, M.2
Sturis, J.3
-
21
-
-
17144371646
-
Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients treated with metformin and a sulfonylurea
-
Kendall DM, Riddle MC, Rosenstock J et al (2005) Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients treated with metformin and a sulfonylurea. Diabetes Care 28: 1083-91
-
(2005)
Diabetes Care
, vol.28
, pp. 1083-1091
-
-
Kendall, D.M.1
Riddle, M.C.2
Rosenstock, J.3
-
22
-
-
33645032922
-
Therapeutic intervention in the GLP-1 pathway in type 2 diabetes
-
Levy JC (2006) Therapeutic intervention in the GLP-1 pathway in type 2 diabetes. Diabetic Medicine 23(Suppl 1): 14-19
-
(2006)
Diabetic Medicine
, vol.23
, Issue.SUPPL. 1
, pp. 14-19
-
-
Levy, J.C.1
-
23
-
-
2542451393
-
Improved glycemic control with no weight increase in patients with type 2 diabetes after once-daily treatment with the long-acting glucagon-like peptide 1 analog liraglutide (NN2211): A 12-week, double-blind, randomized, controlled trial
-
Madsbad S, Schmitz O, Ranstam J (2004) Improved glycemic control with no weight increase in patients with type 2 diabetes after once-daily treatment with the long-acting glucagon-like peptide 1 analog liraglutide (NN2211): a 12-week, double-blind, randomized, controlled trial. Diabetes Care 27: 1335-42
-
(2004)
Diabetes Care
, vol.27
, pp. 1335-1342
-
-
Madsbad, S.1
Schmitz, O.2
Ranstam, J.3
-
25
-
-
0022617246
-
Reduced incretin effect in type 2 (non-insulin-dependent) diabetes
-
Nauck M, Stockmann F, Ebert R, Creutzfeldt W (1986) Reduced incretin effect in type 2 (non-insulin-dependent) diabetes. Diabetologia 29: 46-52
-
(1986)
Diabetologia
, vol.29
, pp. 46-52
-
-
Nauck, M.1
Stockmann, F.2
Ebert, R.3
Creutzfeldt, W.4
-
26
-
-
33750288460
-
Five weeks of treatment with the GLP-1 analogue liraglutide improves glycaemic control and lowers body weight in subjects with type 2 diabetes
-
Nauck MA, Hompesch M, Filipczak R et al (2006) Five weeks of treatment with the GLP-1 analogue liraglutide improves glycaemic control and lowers body weight in subjects with type 2 diabetes. Experimental and Clinical Endocrinology and Diabetes 114: 417-23
-
(2006)
Experimental and Clinical Endocrinology and Diabetes
, vol.114
, pp. 417-423
-
-
Nauck, M.A.1
Hompesch, M.2
Filipczak, R.3
-
27
-
-
34147160214
-
Twelve-week efficacy and tolerability of sitagliptin, a dipeptidyl peptidase-IV (DPP-4) inhibitor in Japanese patients with T2DM
-
9-13 June, Washington, DC. Abstract 537-P
-
Nonaka K, Kakikawa T, Sato A et al (2006) Twelve-week efficacy and tolerability of sitagliptin, a dipeptidyl peptidase-IV (DPP-4) inhibitor in Japanese patients with T2DM. Program and abstracts of the American Diabetes Association 66th Scientific Sessions; 9-13 June, Washington, DC. Abstract 537-P
-
(2006)
Program and abstracts of the American Diabetes Association 66th Scientific Sessions
-
-
Nonaka, K.1
Kakikawa, T.2
Sato, A.3
-
28
-
-
0014188893
-
Plasma insulin responses to oral and intravenous glucose: Studies in normal and diabetic subjects
-
Perley MJ, Kipnis DM (1967) Plasma insulin responses to oral and intravenous glucose: studies in normal and diabetic subjects. Journal of Clinical Investigation 46: 1954-62
-
(1967)
Journal of Clinical Investigation
, vol.46
, pp. 1954-1962
-
-
Perley, M.J.1
Kipnis, D.M.2
-
29
-
-
33845489598
-
Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy in patients with type 2 diabetes mellitus
-
Raz I, Hanefeld M, Xu L et at (2006) Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy in patients with type 2 diabetes mellitus. Diabetologia 49: 2564-71
-
(2006)
Diabetologia
, vol.49
, pp. 2564-2571
-
-
Raz, I.1
Hanefeld, M.2
Xu, L.3
et at4
-
30
-
-
0242269000
-
-
Riddle MC, Rosenstock J, Gerich J; Insulin Glargine 4002 Study Investigators (2003) The treat-to-target trial: randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients. Diabetes Care 26: 3080-6
-
Riddle MC, Rosenstock J, Gerich J; Insulin Glargine 4002 Study Investigators (2003) The treat-to-target trial: randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients. Diabetes Care 26: 3080-6
-
-
-
-
31
-
-
33749364478
-
Exenatide elicits sustained glycaemic control and progressive reduction of body weight in patients with type 2 diabetes inadequately controlled by sulphonylureas with or without metformin
-
Riddle MC, Henry RR, Poon TH et al (2006) Exenatide elicits sustained glycaemic control and progressive reduction of body weight in patients with type 2 diabetes inadequately controlled by sulphonylureas with or without metformin. Diabetes Metabolism Research and Reviews 22: 483-91
-
(2006)
Diabetes Metabolism Research and Reviews
, vol.22
, pp. 483-491
-
-
Riddle, M.C.1
Henry, R.R.2
Poon, T.H.3
-
32
-
-
33751557143
-
Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing pioglitazone therapy in patients with type 2 diabetes: A 24-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group study
-
Rosenstock J, Brazg R, Andryuk PJ et al (2006) Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing pioglitazone therapy in patients with type 2 diabetes: a 24-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group study. Clinical Therapeutics 28: 1556-68
-
(2006)
Clinical Therapeutics
, vol.28
, pp. 1556-1568
-
-
Rosenstock, J.1
Brazg, R.2
Andryuk, P.J.3
-
33
-
-
33846694046
-
Comparison of vildagliptin and rosiglitazone monotherapy in patients with type 2 diabetes: A 24-week, double-blind, randomized trial
-
Rosenstock J, Baron MA, Dejager S et al (2007) Comparison of vildagliptin and rosiglitazone monotherapy in patients with type 2 diabetes: a 24-week, double-blind, randomized trial. Diabetes Care 30: 217-23
-
(2007)
Diabetes Care
, vol.30
, pp. 217-223
-
-
Rosenstock, J.1
Baron, M.A.2
Dejager, S.3
-
34
-
-
33749818721
-
Sitagliptin, a DPP-4 inhibitor, does not inhibit the pharmacokinetics of the sulfonylurea glyburide
-
9-13 June, Washington, DC. Abstract 558-P
-
Ruddy MK, Bergman AJ, Zheng W et al (2006) Sitagliptin, a DPP-4 inhibitor, does not inhibit the pharmacokinetics of the sulfonylurea glyburide. Program and abstracts of the American Diabetes Association 66th Scientific Sessions, 9-13 June 2006, Washington, DC. Abstract 558-P
-
(2006)
Program and abstracts of the American Diabetes Association 66th Scientific Sessions
-
-
Ruddy, M.K.1
Bergman, A.J.2
Zheng, W.3
-
35
-
-
34249716522
-
Gastric inhibitory polypeptide receptors are present in human subcutaneous adipose tissue: Effects of central obesity and weight loss
-
12-15 September, Athens, Greece. Abstract 549
-
Rudovich A, Kaiser S, Engeli S, Pfeiffer AFH (2005) Gastric inhibitory polypeptide receptors are present in human subcutaneous adipose tissue: effects of central obesity and weight loss. Program and abstracts of the European Association for the Study of Diabetes 41st Annual Meeting; 12-15 September 2005; Athens, Greece. Abstract 549
-
(2005)
Program and abstracts of the European Association for the Study of Diabetes 41st Annual Meeting
-
-
Rudovich, A.1
Kaiser, S.2
Engeli, S.3
Pfeiffer, A.F.H.4
-
36
-
-
33644676141
-
Incretin mimetics and dipeptidyl peptidase-IV inhibitors: Potential new therapies for type 2 diabetes mellitus
-
Triplitt C, Wright A, Chiquette E (2006) Incretin mimetics and dipeptidyl peptidase-IV inhibitors: potential new therapies for type 2 diabetes mellitus. Pharmacotherapy 26: 360-74
-
(2006)
Pharmacotherapy
, vol.26
, pp. 360-374
-
-
Triplitt, C.1
Wright, A.2
Chiquette, E.3
-
37
-
-
1842855423
-
Incretins, insulin secretion and type 2 diabetes mellitus
-
Vilsboll T, Holst JJ (2004) Incretins, insulin secretion and type 2 diabetes mellitus. Diabetologia 47: 357-66
-
(2004)
Diabetologia
, vol.47
, pp. 357-366
-
-
Vilsboll, T.1
Holst, J.J.2
-
38
-
-
0037045845
-
Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and ß-cell function in type 2 diabetes: A parallel-group study
-
Zander M, Madsbad S, Madsen JL, Holst JJ (2002) Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and ß-cell function in type 2 diabetes: a parallel-group study. Lancet 359: 824-30
-
(2002)
Lancet
, vol.359
, pp. 824-830
-
-
Zander, M.1
Madsbad, S.2
Madsen, J.L.3
Holst, J.J.4
|