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Potential therapies mimicking the effects of glucagon-like peptide-1 for the treatment of type 2 diabetes
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Rachman J Potential therapies mimicking the effects of glucagon-like peptide-1 for the treatment of type 2 diabetes Diabet Med 2004 21 (Suppl 1) 18 20
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Rachman, J.1
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Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: A parallel-group study
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Zander M Madsbad S Madsen JL Holst JJ Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study Lancet 2002 359 824 830
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0345257136
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Glucagon-like peptide-1 and the islet beta-cell: Augmentation of cell proliferation and inhibition of apoptosis
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Drucker DJ Glucagon-like peptide-1 and the islet beta-cell: augmentation of cell proliferation and inhibition of apoptosis Endocrinology 2003 144 5145 5148
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Endocrinology
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Drucker, D.J.1
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Improved glycemic control with no weight increase in patients with type 2 diabetes after once-daily treatment with the long-acting glucagon-like peptide 1 analog liraglutide (NN2211): A 12-week, double-blind, randomized, controlled trial
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Madsbad S Schmitz O Ranstam J Jakobsen G Matthews DR Improved glycemic control with no weight increase in patients with type 2 diabetes after once-daily treatment with the long-acting glucagon-like peptide 1 analog liraglutide (NN2211): a 12-week, double-blind, randomized, controlled trial Diabetes Care 2004 27 1335 1342
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Development and characterization of a glucagon-like peptide 1-albumin conjugate: The ability to activate the glucagon-like peptide 1 receptor in vivo
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Kim JG Baggio LL Bridon DP Castaigne JP Robitaille MF Jette L et al. Development and characterization of a glucagon-like peptide 1-albumin conjugate: the ability to activate the glucagon-like peptide 1 receptor in vivo Diabetes 2003 52 751 759
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4344667831
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A recombinant human glucagon-like peptide (GLP)-1-albumin protein (albugon) mimics peptidergic activation of GLP-1 receptor-dependent pathways coupled with satiety, gastrointestinal motility, and glucose homeostasis
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Baggio LL Huang Q Brown TJ Drucker DJ A recombinant human glucagon-like peptide (GLP)-1-albumin protein (albugon) mimics peptidergic activation of GLP-1 receptor-dependent pathways coupled with satiety, gastrointestinal motility, and glucose homeostasis Diabetes 2004 53 2492 2500
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2442482515
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Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels, and reduces glucagon levels in type 2 diabetes
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Ahren B Landin-Olsson M Jansson PA Svensson M Holmes D Schweizer A Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels, and reduces glucagon levels in type 2 diabetes J Clin Endocrinol Metab 2004 89 2078 2084
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Twelve- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type 2 diabetes
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Ahren B Gomis R Standl E Mills D Schweizer A Twelve- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type 2 diabetes Diabetes Care 2004 27 2874 2880
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Ahren, B.1
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Vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed {beta}-cell function in patients with type 2 diabetes
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Mari A Sallas WM He YL Watson C Ligueros-Saylan M Dunning BE et al. Vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed {beta}-cell function in patients with type 2 diabetes J Clin Endocrinol Metab 2005 90 4888 4894
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Mari, A.1
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19944427998
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(2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a] pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl) butan-2-amine: A potent, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
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Kim D Wang L Beconi M Eiermann GJ Fisher MH He H et al. (2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H) -yl]-1-(2,4,5-trifluorophenyl) butan-2-amine: a potent, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes J Med Chem 2005 48 141 151
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Kim, D.1
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Fisher, M.H.5
He, H.6
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18144401971
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Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes
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Defronzo RA Ratner RE Han J Kim DD Fineman MS Baron AD Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes Diabetes Care 2005 28 1092 1100
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Defronzo, R.A.1
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Baron, A.D.6
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15
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7444228521
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Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes
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Buse JB Henry RR Han J Kim DD Fineman MS Baron AD for the Exenatide-113 Clinical Study Group Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes Diabetes Care 2004 27 2628 2635
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Buse, J.B.1
Henry, R.R.2
Han, J.3
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17144371646
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Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea
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Kendall DM Riddle MC Rosenstock J Zhuang D Kim DD Fineman MS Baron AD Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea Diabetes Care 2005 28 1083 1091
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Kendall, D.M.1
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Zhuang, D.4
Kim, D.D.5
Fineman, M.S.6
Baron, A.D.7
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17
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26944477362
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Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: A randomized trial
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Heine RJ Van Gaal LF Johns D Mihm MJ Widel MH Brodows RG Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: a randomized trial Ann Intern Med 2005 143 559 569
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Heine, R.J.1
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3342971029
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Additive effects of glucagon-like peptide 1 and pioglitazone in patients with type 2 diabetes
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Zander M Christiansen A Madsbad S Holst JJ Additive effects of glucagon-like peptide 1 and pioglitazone in patients with type 2 diabetes Diabetes Care 2004 27 1910 1914
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Zander, M.1
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33645037183
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Effect of MK-0431, a dipeptidyl peptidase IV (DPP-IV) inhibitor, on glycemic control after 12 weeks in patients with type 2 diabetes
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(Abstract)
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Hanefeld M Herman G Mickel C McGowan A Wu M Zhao P Stein P Effect of MK-0431, a dipeptidyl peptidase IV (DPP-IV) inhibitor, on glycemic control after 12 weeks in patients with type 2 diabetes Diabetologia 2005 48 A287 (Abstract)
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Diabetologia
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Hanefeld, M.1
Herman, G.2
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31144459380
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Twelve-week efficacy and tolerability of MK-0431, a dipeptidyl peptidase IV (DPP-IV) inhibitor, in the treatment of type 2 diabetes
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(Abstract)
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Scott R Herman G Zhao P Yee J De La Cruz J Wu L et al. Twelve-week efficacy and tolerability of MK-0431, a dipeptidyl peptidase IV (DPP-IV) inhibitor, in the treatment of type 2 diabetes Diabetologia 2005 48 A287 (Abstract)
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Scott, R.1
Herman, G.2
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Wu, L.6
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4644300651
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Effectiveness of progressive dose-escalation of exenatide (exendin-4) in reducing dose-limiting side effects in subjects with type 2 diabetes
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Fineman MS Shen LZ Taylor K Kim DD Baron AD Effectiveness of progressive dose-escalation of exenatide (exendin-4) in reducing dose-limiting side effects in subjects with type 2 diabetes Diabetes Metab Res Rev 2004 20 411 417
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Fineman, M.S.1
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23744443103
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Exenatide-induced reductions in A1c and body weight in long-term trials are not explained by gastrointestinal side effects
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(Abstract)
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Maggs D Kim D Holcombe J Han J Shen L Ruggles J Fineman M Exenatide-induced reductions in A1c and body weight in long-term trials are not explained by gastrointestinal side effects Diabetes 2005 54 A120 (Abstract)
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Diabetes
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Maggs, D.1
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23744444000
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Improvements in cardiovascular risk factors accompanied sustained effects on glycemia and weight reduction in patients with type 2 diabetes treated with exenatide for 82 weeks
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(Abstract)
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Kendall DM Kim D Poon T Han J Schnabel C Fineman M et al. Improvements in cardiovascular risk factors accompanied sustained effects on glycemia and weight reduction in patients with type 2 diabetes treated with exenatide for 82 weeks Diabetes 2005 54 A4 (Abstract)
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Kendall, D.M.1
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Han, J.4
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