Natural genetic variation in lycopene epsilon cyclase tapped for maize biofortification

Science

Volumn 319, Issue 5861, 2008, Pages 330-333

  Harjes, Carlos E ^a,j   Rocheford, Torbert R ^b   Bai, Ling ^c   Brutnell, Thomas P ^c   Kandianis, Catherine Bermudez ^b   Sowinski, Stephen G ^d   Stapleton, Ann E ^e   Vallabhaneni, Ratnakar ^f,g   Williams, Mark ^d   Wurtzel, Eleanore T ^f,g   Yan, Jianbing ^h   Buckler, Edward S ^a,i  

^a Department of Obstetrics Gynecology   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c United States Department of Agriculture Agricultural Research Service and Boyce Thompson Institute for Plant Research   (United States)

^d DUPONT COMPANY   (United States)

^e UNIVERSITY OF NORTH CAROLINA WILMINGTON   (United States)

^f CITY UNIVERSITY OF NEW YORK   (United States)

^g CITY UNIVERSITY OF NEW YORK   (United States)

^h INTERNATIONAL MAIZE AND WHEAT IMPROVEMENT CENTER CIMMYT   (Mexico)

ⁱ AGRICULTURAL RESEARCH SERVICE   (United States)

^j MONSANTO COMPANY   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CAROTENE; BETA CAROTENE; BETA CRYPTOXANTHIN; BIOLOGICAL MARKER;

DEVELOPING WORLD; DIET; ENZYME ACTIVITY; GENETIC VARIATION; MAIZE; MUTATION; POLYMORPHISM; SELECTIVE BREEDING; VITAMIN;

ARTICLE; DEVELOPING COUNTRY; GENE EXPRESSION; GENE MAPPING; GENETIC ANALYSIS; GENETIC LINKAGE; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HEALTH HAZARD; HUMAN; MAIZE; MUTAGENESIS; PRIORITY JOURNAL; RETINOL DEFICIENCY;

BASE SEQUENCE; BETA CAROTENE; BREEDING; CAROTENOIDS; CROSSES, GENETIC; GENE EXPRESSION REGULATION, PLANT; HAPLOTYPES; INTRAMOLECULAR LYASES; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NUTRITIVE VALUE; POLYMORPHISM, GENETIC; QUANTITATIVE TRAIT LOCI; VARIATION (GENETICS); XANTHOPHYLLS; ZEA MAYS;

AFRICA; SUB-SAHARAN AFRICA;

ZEA MAYS;

EID: 38349114236     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1150255     Document Type: Article

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30. We thank S. Islam, C. Paul, W. Liu, and W. White for running HPLC on samples; H. Yates for support of molecular genetics; and N. Stevens for technical editing of the manuscript. This work was supported by NSF DBI-0321467 (to E.S.B.), U.S. Agency for International Development (to T.R.R.), HarvestPlus (to T.R.R.), NIH (S06-GM08225 to E.T.W.), Professional Staff Congress - CUNY research award (to E.T.W.), New York State (to E.T.W.), NSF DBI-0604923 (to T.R.R), TRIAD Foundation (L.B. and T.P.B.), U.S. Department of Agriculture (USDA) Cooperative State Research, Education, and Extension Service (CSREES), National Research Initiative grant 2003-00745 (to A.E.S.), and USDA - Agricultural Research Service (to E.S.B.). Mention of trade names or commercial products in this publication is solely for the purpose of providing specific information and does not imply recommendation or endorsement by the USDA.