Importance of raw material attributes for modeling ribbon and granule properties in roller compaction: Multivariate analysis on roll gap and NIR spectral slope as process critical control parameters

Journal of Pharmaceutical Innovation

Volumn 2, Issue 3-4, 2007, Pages 106-124

  Soh, Josephine L P ^a   Boersen, Nathan ^a   Carvajal, M Teresa ^a   Morris, Kenneth R ^a   Peck, Garnet E ^a   Pinal, Rodolfo ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

Material characterization; Microcrystalline cellulose; Multivariate data analysis; Near infrared spectroscopy; Process analytical technology; Roller compaction

Indexed keywords

BIOMATERIAL; DRUG;

ARTICLE; DRUG MANUFACTURE; MATERIAL STATE; MULTIVARIATE ANALYSIS; NEAR INFRARED SPECTROSCOPY; PARTICLE SIZE; PHYSICAL CHEMISTRY; PREDICTION; PRIORITY JOURNAL; PROCESS CONTROL; PROCESS MODEL; PROCESS MONITORING; PROCESS OPTIMIZATION; TABLET PROPERTY;

EID: 38349080040     PISSN: 18725120     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12247-007-9013-z     Document Type: Article

References (17)

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