An interaction between the norepinephrine transporter and monoamine oxidase A polymorphisms, and novelty-seeking personality traits in Korean females

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 32, Issue 1, 2008, Pages 238-242

  Lee, Boung Chul ^a   Yang, Jae Won ^b   Lee, So Hee ^c   Kim, Seung Hyun ^b   Joe, Sook Haeng ^b   Jung, In Kwa ^b   Choi, Ihn Geun ^a   Ham, Byung Joo ^a  

^a Hallym University Medical Center   (South Korea)

^b Korea University College of Medicine   (South Korea)

^c National Medical Center   (South Korea)

Author keywords

Genes; Monoamine oxidase A; Norepinephrine transporter; Personality; Polymorphism

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; NORADRENALIN TRANSPORTER;

ADRENERGIC SYSTEM; ADULT; ARTICLE; DNA POLYMORPHISM; FEMALE; GENOTYPE; HUMAN; KOREA; NORMAL HUMAN; PERSONALITY; PERSONALITY TEST; POPULATION GENETICS; SCORING SYSTEM; VARIABLE NUMBER OF TANDEM REPEAT; VOLUNTEER;

ADULT; ANALYSIS OF VARIANCE; EXPLORATORY BEHAVIOR; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; KOREA; MINISATELLITE REPEATS; MONOAMINE OXIDASE; NEUROPSYCHOLOGICAL TESTS; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; PERSONALITY; PERSONALITY INVENTORY; POLYMORPHISM, GENETIC;

EID: 38349060172     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2007.08.014     Document Type: Article

References (52)

1. Berridge C.W., and Waterhouse B.D. The locus coeruleus-noradrenergic system: modulation of behavioral state and state-dependent cognitive processes. Brain Res Brain Res Rev 42 (2003) 33-84
2. Brunner H.G., Nelen M.R., van Zandvoort P., Abeling N.G., van Gennip A.H., Wolters E.C., et al. X-linked borderline mental retardation with prominent behavioral disturbance: phenotype, genetic localization, and evidence for disturbed monoamine metabolism. Am J Hum Genet 52 (1993) 1032-1039
3. Bruss M., Kunz J., Lingen B., and Bonisch H. Chromosomal mapping of the human gene for the tricyclic antidepressant-sensitive noradrenaline transporter. Hum Genet 91 (1993) 278-280
4. Cases O., Seif I., Grimsby J., Gaspar P., Chen K., Pournin S., et al. Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA. Science 268 (1995) 1763-1766
5. Cloninger C.R., Bayon C., and Svrakic D.M. Measurement of temperament and character in mood disorders: a model of fundamental states as personality types. J Affect Disord 51 (1998) 21-32
6. Daffner K.R., Mesulam M.M., Holcomb P.J., Calvo V., Acar D., Chabrerie A., et al. Disruption of attention to novel events after frontal lobe injury in humans. J Neurol Neurosurg Psychiatry 68 (2000) 18-24
7. Deckert J., Catalano M., Syagailo Y.V., Bosi M., Okladnova O., Di Bella D., et al. Excess of high activity monoamine oxidase A gene promoter alleles in female patients with panic disorder. Hum Mol Genet 8 (1999) 621-624
8. Dias R., and Honey R.C. Involvement of the rat medial prefrontal cortex in novelty detection. Behav Neurosci 116 (2002) 498-503
9. Diaz-Marsa M., Carrasco J.L., Hollander E., Cesar J., and Saiz-Ruiz. Decreased platelet monoamine oxidase activity in female anorexia nervosa. Acta Psychiatr Scand 101 (2000) 226-230
10. Du L., Bakish D., Ravindran A., and Hrdina P.D. MAO-A gene polymorphisms are associated with major depression and sleep disturbance in males. NeuroReport 15 (2002) 2097-2101
11. Ebstein R.P., Nemanov L., Klotz I., Gritsenko I., and Belmaker R.H. Additional evidence for an association between the dopamine D4 receptor (D4DR) exon III repeat polymorphism and the human personality trait of Novelty Seeking. Mol Psychiatry 2 (1997) 472-477
12. Ebstein R.P., Benjamin J., and Belmaker R.H. Personality and polymorphisms of genes involved in aminergic neurotransmission. Eur J Pharmacol 410 (2000) 205-214
13. Garpenstrand H., Norton N., Damberg M., Rylander G., Forslund K., Mattila-Evenden M., et al. A regulatory monoamine oxidase a promoter polymorphism and personality traits. Neuropsychobiology 46 (2002) 190-193
14. Gebhardt C., Leisch F., Schussler P., Fuchs K., Stompe T., Sieghart W., et al. Non-association of dopamine D4 and D2 receptor genes with personality in healthy individuals. Psychiatr Genet 10 (2000) 131-137
15. Gerra G., Avanzini P., Zaimovic A., Sartori R., Bocchi C., Timpano M., et al. Neurotransmitters, neuroendocrine correlates of sensation-seeking temperament in normal humans. In: Zambelli U., Delsignore R., Gardini F., Talarico E., and Brambilla F. (Eds). Neuropsychobiology vol. 39 (1999) 207-213
16. Gerra G., Zaimovic A., Avanzini P., Chittolini B., Giucastro G., Caccavari R., et al. Neurotransmitter-neuroendocrine responses to experimentally induced aggression in humans: influence of personality variable. Psychiatry Res 66 (1997) 33-43
17. Gerra G., Zaimovic A., Ampollini R., Giusti F., Delsignore R., Raggi M.A., et al. Experimentally induced aggressive behavior in subjects with 3,4-methylenedioxy-methamphetamine ("Ecstasy") use history: psychobiological correlates. J Subst Abuse 13 (2001) 471-491
18. Gerra G., Garofano L., Bosari S., Pellegrini C., Zaimovic A., Moi G., et al. Analysis of monoamine oxidase A (MAO-A) promoter polymorphism in male heroin-dependent subjects: behavioural and personality correlates. J Neural Transm 111 (2004) 611-621
19. Hakamata Y., Takahashi N., Ishihara R., Saito S., Ozaki N., Honjo S., et al. No association between monoamine oxidase A promoter polymorphism and personality traits in Japanese females. Neurosci Lett 389 (2005) 121-123
20. Ham B.J., Choi M.J., Lee H.J., Kang R.H., and Lee M.S. Reward dependence is related to norepinephrine transporter T-182C gene polymorphism in a Korean population. Psychiatr Genet 15 (2005) 145-147
21. Hahn D.W., Lee C.H., and Chon K.K. Korean Adaption of Spielberger's STAI(K-STAI). Korean J Health Psychol 1 (1996) 1-14
22. Han H.M., Yeom T.H., Shin Y.W., Kim K.H., Yoon D.J., and Cheong K.J. Standardization study of Korean version Beck Depression Inventory. J Korean Neuropsychiat Assoc 25 (1986) 487-500
23. Hill S.Y., Zezza N., Wipprecht G., Locke J., and Neiswanger K. Personality traits and dopamine receptors (D2 and D4): linkage studies in families of alcoholics. Am J Med Genet 88 (1999) 634-641
24. Huang Y.Y., Cate S.P., Battistuzzi C., Oquendo M.A., Brent D., and Mann J.J. An association between a functional polymorphism in the monoamine oxidase a gene promoter, impulsive traits and early abuse experiences. Neuropsychopharmacology 29 (2004) 1498-1505
25. Inoue K., Itoh K., Yoshida K., Shimizu T., and Suzuki T. Positive association between T-182C polymorphism in the norepinephrine transporter gene and susceptibility to major depressive disorder in a Japanese population. Neuropsychobiology 50 (2004) 301-304
26. Jorm A.F., Henderson A.S., Jacomb P.A., Christensen H., Korten A.E., Rodgers B., et al. Association of a functional polymorphism of the monoamine oxidase A gene promoter with personality and psychiatric symptoms. Psychiatr Genet 10 (2000) 87-90
27. Kim S.J., Kim Y.S., Kim S.Y., Lee H.S., and Kim C.H. An association study of catechol-O-methyltransferase and monoamine oxidase A polymorphisms and personality traits in Koreans. Neurosci Lett 401 (2006) 154-158
28. Levy E.R., Powell J.F., Buckle V.J., Hsu Y.P., Breakefield X.O., and Craig I.W. Localization of human monoamine oxidase-A gene to Xp11.23-11.4 by in situ hybridization: implications for Norrie disease. Genomics 5 (1989) 368-370
29. Manor I., Tyano S., Mel E., Eisenberg J., Bachner-Melman R., Kotler M., et al. Family-based and association studies of monoamine oxidase A and attention deficit hyperactivity disorder (ADHD): preferential transmission of the long promoter-region repeat and its association with impaired performance on a continuous performance test (TOVA). Mol Psychiatry 7 (2002) 626-632
30. Manuck S.B., Flory J.D., Ferrell R.E., Mann J.J., and Muldoon M.F. A regulatory polymorphism of the monoamine oxidase-A gene may be associated with variability in aggression, impulsivity, and central nervous system serotonergic responsivity. Psychiatry Res 95 (2000) 9-23
31. Manuck S.B., Flory J.D., Muldoon M.F., and Ferrell R.E. Central nervous system serotonergic responsivity and aggressive disposition in men. Physiol Behav 77 (2002) 705-709
32. Meyer J., Wiedemann P., Okladnova O., Bruss M., Staab T., Stober G., et al. Cloning and functional characterization of the human norepinephrine transporter gene promoter. J Neural (1998) 1341-1350
33. Miguita K., Cordeiro Q., Shavitt R.G., Miguel E.C., and Vallada H. Association study between the 1287 A/G exonic polymorphism of the norepinephrine transporter (NET) gene and obsessive-compulsive disorder in a Brazilian sample. Rev Bras Psiquiatr 28 (2006) 158-159
34. Moron J.A., Brockington A., Wise R.A., Rocha B.A., and Hope B.T. Dopamine uptake through the norepinephrine transporter in brain regions with low levels of the dopamine transporter: evidence from knock-out mouse lines. J Neurosci 22 (2002) 389-395
35. Noble E.P., Ozkaragoz T.Z., Ritchie T.L., Zhang X., Belin T.R., and Sparkes R.S. D2 and D4 dopamine receptor polymorphisms and personality. Am J Med Genet 81 (1998) 257-267
36. Noblett K.L., and Coccaro E.F. Molecular genetics of personality. Curr Psychiatry Rep 7 (2005) 73-80
37. Okuyama Y., Ishiguro H., Nankai M., Shibuya H., Watanabe A., and Arinami T. Identification of a polymorphism in the promoter region of DRD4 associated with the human novelty seeking personality trait. Mol Psychiatry 5 (2000) 64-69
38. Rebec G.V., Grabner C.P., Johnson M., Pierce R.C., and Bardo M.T. Transient increases in catecholaminergic activity in medial prefrontal cortex and nucleus accumbens shell during novelty. Neuroscience 76 (1997) 707-714
39. Ryu S.H., Lee S.H., Lee H.J., Cha J.H., Ham B.J., Han C.S., et al. Association between norepinephrine transporter gene polymorphism and major depression. Neuropsychobiology 49 (2004) 174-177
40. Sabol S.Z., Hu S., and Hamer D. A functional polymorphism in the monoamine oxidase A gene promoter. Hum Genet 103 (1998) 273-279
41. Samochowiec J., Lesch K.P., Rottmann M., Smolka M., Syagailo Y.V., Okladnova O., et al. Association of a regulatory polymorphism in the promoter region of the monoamine oxidase A gene with antisocial alcoholism. Psychiatry Res 86 (1999) 67-72
42. Samochowiec J., Rybakowski F., Czerski P., Zakrzewska M., Stepien G., Pelka-Wysiecka, et al. Polymorphisms in the dopamine, serotonin, and norepinephrine transporter genes and their relationship to temperamental dimensions measured by the Temperament and Character Inventory in healthy volunteers. Neuropsychobiology 43 (2001) 248-253
43. Samochowiec J., Kucharska-Mazur J., Rybakowski F., Ostapowicz A., Horodnicki J., Rozpara M., et al. Norepinephrine transporter polymorphism and personality trait of reward dependence in male alcoholics. Pharmacopsychiatry 35 (2002) 195-196
44. Savitz J.B., and Ramesar R.S. Genetic variants implicated in personality: a review of the more promising candidates. Am J Med Genet B Neuropsychiatr Genet 131 (2004) 20-32
45. Serretti A., Mandelli L., Lorenzi C., Landoni S., Calati R., Insacco C., et al. Temperament and character in mood disorders: influence of DRD4, SERTPR, TPH and MAO-A polymorphisms. Neuropsychobiology 53 (2006) 9-16
46. Shiraishi H., Suzuki A., Fukasawa T., Aoshima T., Ujiie Y., Ishii G., et al. Monoamine oxidase A gene promoter polymorphism affects novelty seeking and reward dependence in healthy study participants. Psychiatr Genet 16 (2006) 55-58
47. Sung S.M., Kim J.H., Yang E., Abrams K.Y., and Lyoo I.K. Reliability and validity of the Korean version of the Temperament and Character Inventory. Compr Psychiatry 43 (2002) 235-243
48. Tomitaka M., Tomitaka S., Otuka Y., Kim K., Matuki H., Sakamoto K., et al. Association between novelty seeking and dopamine receptor D4 (DRD4) exon III polymorphism in Japanese subjects. Am J Med Genet 88 (1999) 469-471
49. Tsai S.J., Wang Y.C., and Hong C.J. Allelic variants of the alpha1a adrenoceptor and the promoter region of the alpha2a adrenoceptor and temperament factors. Am J Med Genet 105 (2001) 96-98
50. Tsai S.J., Wang Y.C., and Hong C.J. Norepinephrine transporter and alpha(2c) adrenoceptor allelic variants and personality factors. Am J Med Genet 114 (2002) 649-651
51. Yu Y.W., Yang C.W., Wu H.C., Tsai S.J., Hong C.J., Chen M.C., et al. Association study of a functional MAOA-uVNTR gene polymorphism and personality traits in Chinese young females. Neuropsychobiology 52 (2005) 118-121
52. Zill P., Engel R., Baghai T.C., Juckel G., Frodl T., Muller-Siecheneder F., et al. Identification of a naturally occurring polymorphism in the promoter region of the norepinephrine transporter and analysis in major depression. Neuropsychopharmacology 26 (2002) 489-493