Neurotransmitters, neuroendocrine correlates of sensation-seeking temperament in normal humans

Neuropsychobiology

Volumn 39, Issue 4, 1999, Pages 207-213

  Gerra, G ^a,f   Avanzini, P ^b   Zaimovic, A ^a   Sartori, R ^a   Bocchi, C ^a   Timpano, M ^a   Zambelli, U ^a   Delsignore, R ^c   Gardini, F ^d   Talarico, E ^b   Brambilla, F ^e  

^a Az USL di Parma   (Italy)

^b Ospedale di Parma   (Italy)

^c Istituto di Clinica Medica I   (Italy)

^d UNIVERSITY OF PARMA   (Italy)

^e IRCS S Raffaele   (Italy)

^f Servizio Tossicodipendenze   (Italy)

Author keywords

Cortisol; Epinephrine; Norepinephrine; Novelty sensation seeking; Prolactin; Testosterone

Indexed keywords

ADRENALIN; HYDROCORTISONE; NEUROTRANSMITTER; NORADRENALIN; PROLACTIN; TESTOSTERONE;

ADULT; ARTICLE; HORMONE BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; MALE; MONOAMINERGIC SYSTEM; NEUROENDOCRINOLOGY; NORADRENERGIC SYSTEM; NORMAL HUMAN; PERSONALITY; PRIORITY JOURNAL; PSYCHOPHYSIOLOGY; SCORING SYSTEM; SENSATION; STATISTICAL ANALYSIS; TEMPERAMENT;

ADULT; CORTISONE; EPINEPHRINE; EXPLORATORY BEHAVIOR; HUMANS; MALE; MIDDLE AGED; NEUROSECRETORY SYSTEMS; NEUROTRANSMITTER AGENTS; NOREPINEPHRINE; PROLACTIN; RISK-TAKING; TEMPERAMENT; TESTOSTERONE;

EID: 0032906846     PISSN: 0302282X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000026586     Document Type: Article

References (53)

1. Zuckerman M: The psychobiological model for impulsive unsocialized sensation seeking: A comparative approach. Neuropsychobiology 1996;14:125-129.
2. Cloninger CR, Svrakic DM, Przybeck TR: A psychobiological model of temperament and character. Arch Gen Psychiatry 1993;50:975-990.
3. Zuckerman M, Cloninger CR: Relationships between Cloninger's, Zuckerman's, and Eysenck's dimensions of personality. Pers Individ Differences 1996;21:283-285.
4. Cloninger CR: The genetics and psychobiology of the seven-factor model of personality; in Silk KR (ed): Biology of Personality Disorders. Washington, American Psychiatric Press, 1998, pp 63-91.
5. Gelernter J, Vandenbergh D, Kruger SD, et al: The dopamine transporter protein gene (SLC1A3): Primary linkage mapping and linkage studies in Tourette syndrome. Genomics 1995;30:459-463.
6. Ebstein RP, Novick O, Umansky R, et al: Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of novelty seeking. Nat Genet 1996;12: 78-80.
7. Benjamin J, Li L, Patterson C, et al: Population and familial association between the d4 dopamine receptor and measures of novelty seeking. Nat Genet 1996;12:81-84.
8. Tiihonen J, Kuikka J, Bergstrom K, et al: Altered striatal dopamine re-uptake site densities in habitually violent and non-violent alcoholics. Nat Med 1995;1:654-657.
9. Ruegg RG, Gilmore J, Ekstrom RD, et al: Clomipramine challenge responses covary with Tridimensional Personality Questionnaire scores in healthy subjects. Biol Psychiatry 1997;42:1123-1129.
10. Corr PJ, Pickering AD, Gray JA: Personality and reinforcement in associative and instrumental learning. Pers Individ Differences 1995;19:47-71.
11. Zuckerman M: The psychophysiology of sensation seeking. J Pers 1990;58:313-345.
12. Netter P, Henning J, Road IS: Serotonin and dopamine as mediators of sensation seeking behavior. Neuropsychobiology 1996;34:155-165.
13. Dellu F, Piazza PV, Mayo W, et al: Novelty seeking in rats. Biobehavioral characteristics and possible relationship with the sensationseeking trait in man. Neuropsychobiology 1996;34:136-145.
14. D'Angio MD, Serrano A, Driscoll P, Scatton B: Stressful environmental stimuli increase extracellular DOPAC levels in the prefrontal cortex of hypoemotional (Roman high-avoidance) but not hyperemotional (Roman low-avoidance) rats. An in vivo voltametric study. Brain Res 1988;451:237-247.
15. Walker CD, Rivest RW, Meancy MJ, Aubert ML: Differential activation of the pituitaryadrenocortical axis after stress in the rat: Use of two genetically selected tines (Roman low- and high-avoidance rats). J Endocrinol 1989;123: 477-485.
16. Giorgi O, Orlandi M, Escoribuela RM, et al: GABAergic and dopaminergic transmission in the brains of Roman high-avoidance rats. Brain Res 1994;638:133-138.
17. Siegel J, Driscoll P: Recent developments in an animal model of visual evoked potential augmenting/reducing and sensation seeking behavior. Neuropsychobiology 1996;34:130-135.
18. Ballenger JC, Post RM, Jimerson DC, et al: Biochemical correlates of personality traits in normals: An exploratory study. Pers Individ Differences 1983;4:615-625.
19. Arque JM, Beltri R, Torrubia R: Personality, biolectric profile, and platelet monoamine oxidase activity in psychophysiological disorders: Headaches, insomnia, and loss of consciousness due to neurocirculatory dystonia. Psychiatry Psychobiol 1988;3:263-267.
20. Zuckerman M: Behavioral Expressions and Biosocial Bases of Sensation Seeking. Cambridge, Cambridge University Press, 1994.
21. Johansson F, Almay BGL, von Knorring L, Terrenius LA: Personality traits in chronic patients related to endorphin levels in cerebrospinal fluid. Psychiatry Res 1979;1:231-239.
22. Roy A, Adinoff B, Linnoila M: Acting out hostility in normal volunteers: Negative correlation with levels of 5-HIAA in cerebrospinal fluid. Psychiatry Res 1988;24:187-194.
23. Siever LJ, Davis KL: A psychobiologic perspective on the personality disorders. Am J Psychiatry 1991;148:1646-1658.
24. Wang S, Mason J, Charney D, et al: Relationship between hormonal profile and novelty seeking in combat-related posttraumatic stress disorder. Biol Psychiatry 1997;41:145-151.
25. Muller FF, Nisticó G, Scapagnini U: Neurotransmitters and Anterior Pituitary Function. New York, Academic Press, 1977.
26. Balada F, Torrubia R, Arque JM : Gonadal hormones correlates of sensation seeking and anxiety in healthy human females. Neuropsychobiology 1993;27:91-96.
27. Balada F, Torrubia R, Arque JM: Thyroid hormone correlates of sensation seeking and anxiety in healthy human females. Neuropsychobiology 1992;25:208-213.
28. Zuckerman M: Psychobiology of Personality. Cambridge, Cambridge University Press, 1991.
29. Daitzman RJ, Zuckerman M, Sammelwitz P, Ganjam V: Sensation seeking and gonadal hormones. J Biosoc Sci 1978;10:401-408.
30. Daitzman RJ, Zuckerman M: Disinhibitory sensation seeking, personality, and gonadal hormones. Pers Individ Differences 1980;1: 103-110.
31. Dabbs JM Jr, Hopper CH, Jurkovic GJ: Testosterone and personality among college students and military veterans. Pers Individ Differences 1991;11:1263-1269.
32. Garvey MJ, Noyes R Jr, Cook B, Blum N: Preliminary confirmation of the proposed link beween reward-dependences traits and norepinephrine. Psychiatry Res 1996;65:61-64.
33. Spitzer RL, Williams JBW, Gibbon M, First MB: Structured Clinical Interview According ot DSM-III-R. Washington, American Psychiatric Press, 1990.
34. Pfohl B, Blum N, Zimmerman M, Stangl D: Structured Interview for Personality Disorders, revised. Iowa City, University of Iowa, 1989.
35. Hunt C, Andrews G: Measuring personality disorder. The use of self-report questionnaires. J Pers Disord 1992;6:125-133.
36. Holmes TH, Rahe RH: The Social Readjustment Rating Scale. J Psychosom Res 1967;11: 213-218.
37. Zuckerman M: A critical look at three arousal constructs in personality theories: Optimal levels of arousal, strength of the nervous system, and sensitivities to signals of reward and punishment; in Strelau J, Eysenck HJ (ed): Personality Dimensions and Arousal. New York, Plenum Publishing, 1987, pp 217-231.
38. Grossi G, Borgassi A, Lipid A, Battistoni R: A fully automated catecholamines analyzer on cartridge extraction and HPLC separation. Chromatographia 1987;24:842-846.
39. Smedes F, Kraak JK, Poppe H: Simple and fast solvent extraction system for selective and quantitative isolation of adrenaline, noradrenaline and dopamine from plasma and urine. Chromatogr Biomed Appl 1962;231:25-39.
40. Gerra G, Fertonani G, Zaimovic A, et al: Hostility in heroin abusers subtypes: Fluoxetine and naltrexone treatment. Prog Neuropsychopharmacol Biol Psychiatry 1995;19:1225-1237.
41. Cloninger CR: A unified biosocial theory of personality and its role in the development of anxiety states. Psychiatr Dev 1986;3:167-226.
42. Calogero AE, Bagdy G, Szemeredi K, et al: Mechanisms of serotonin receptor agonist-induced activation of the hypothalamic-pituitary-adrenal axis in the rat. Endocrinology 1990;126:1888-1894.
43. Monteleone P, Bortolotti F, Orazzo C, Serino I, Maj M: Differences between morning and afternoon hormonal responses to D-fenfluramine in healthy humans. Psychoneuroendocrinology 1997;22:79-87.
44. Vingerhoets AJ, Ratliff-Crain J, Jabaaij L, et al: Self-reported stressors, symptom complaints and psychobiological functioning-II: Psyehoneuroendocrine variables. J Psychosom Res 1996;40:191-203.
45. Gerra O, Zaimovic A, Avanzini P, et al: Neurotransmitter-neuroendocrine responses to experimentally induced aggression in humans: Influence of personality variable. Psychiatry Res 1997;66:33-43.
46. Gerra G, Terzi C, Delsignore R, et al: Neuroendocrine responses to physical exercise in adolescents with low self esteem and frustration. Neuroendocrinol Lett 1991;13:367-375.
47. Joyce PR, Mulder RT, Cloninger CR: Temperament predicts clomipramine and desipramine response in major depression. J Affective Disord 1994;30:35-46.
48. Vaananen I, Mantysaari M, Huttunen P, Komulainen J, Vihko V: The effects of a 4-day march on the lower extremities and hormonal balance. Milit Med 1997;162:118-122.
49. Urhausen A, Gabriel H, Kindermann W: Blood hormones as markers of training stress and overtraining. Sport Med 1995;4:251-276.
50. Higley JD, Mehlman PT, Poland RE, Taub DM, Vickers J, Suomi SJ, Linnoila M: CST testosterone and 5-HIAA correlate with different types of aggressive behaviors. Biol Psychiatry 1996;11:1067-1082.
51. Virkkunen M, Goldman D, Linnoila M: Serotonin in alcoholic violent offenders. Ciba Found Symp 1996;194:168-182.
52. Gerra G, Avanzini P, Zaimovic A, et al: Neurotransmitter and endocrine modulation of aggressive behavior and its components in normal humans. Behav Brain Res 1996;81:19-24.
53. Howard MO, Kivlahan D, Walker RD: Cloninger's tridimensional theory of personality and psychopathology: Applications to substance use disorders. J Stud Alcohol 1997;58:48-66.